JPWO2020009132A5 - - Google Patents
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- Publication number
- JPWO2020009132A5 JPWO2020009132A5 JP2020529019A JP2020529019A JPWO2020009132A5 JP WO2020009132 A5 JPWO2020009132 A5 JP WO2020009132A5 JP 2020529019 A JP2020529019 A JP 2020529019A JP 2020529019 A JP2020529019 A JP 2020529019A JP WO2020009132 A5 JPWO2020009132 A5 JP WO2020009132A5
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- JP
- Japan
- Prior art keywords
- salt
- formula
- compound represented
- compound
- equation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000001875 compounds Chemical class 0.000 claims description 40
- 150000003839 salts Chemical class 0.000 claims description 20
- 238000000034 method Methods 0.000 claims description 16
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 9
- 239000003153 chemical reaction reagent Substances 0.000 claims description 7
- WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 claims description 6
- 239000012320 chlorinating reagent Substances 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- OISVCGZHLKNMSJ-UHFFFAOYSA-N 2,6-dimethylpyridine Chemical group CC1=CC=CC(C)=N1 OISVCGZHLKNMSJ-UHFFFAOYSA-N 0.000 claims 6
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical group CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims 6
- CTSLXHKWHWQRSH-UHFFFAOYSA-N oxalyl chloride Chemical group ClC(=O)C(Cl)=O CTSLXHKWHWQRSH-UHFFFAOYSA-N 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- XWKFPIODWVPXLX-UHFFFAOYSA-N 2-methyl-5-methylpyridine Natural products CC1=CC=C(C)N=C1 XWKFPIODWVPXLX-UHFFFAOYSA-N 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 2
- 239000003054 catalyst Substances 0.000 claims 2
- UKVIEHSSVKSQBA-UHFFFAOYSA-N methane;palladium Chemical compound C.[Pd] UKVIEHSSVKSQBA-UHFFFAOYSA-N 0.000 claims 2
- 150000001299 aldehydes Chemical class 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023134392A JP2023159297A (ja) | 2018-07-04 | 2023-08-22 | ジアリールピリジン誘導体の製造方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018127197 | 2018-07-04 | ||
| JP2018127197 | 2018-07-04 | ||
| PCT/JP2019/026395 WO2020009132A1 (ja) | 2018-07-04 | 2019-07-03 | ジアリールピリジン誘導体の製造方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023134392A Division JP2023159297A (ja) | 2018-07-04 | 2023-08-22 | ジアリールピリジン誘導体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020009132A1 JPWO2020009132A1 (ja) | 2021-07-08 |
| JPWO2020009132A5 true JPWO2020009132A5 (enExample) | 2022-07-01 |
| JP7337058B2 JP7337058B2 (ja) | 2023-09-01 |
Family
ID=69059540
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020529019A Active JP7337058B2 (ja) | 2018-07-04 | 2019-07-03 | ジアリールピリジン誘導体の製造方法 |
| JP2023134392A Pending JP2023159297A (ja) | 2018-07-04 | 2023-08-22 | ジアリールピリジン誘導体の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023134392A Pending JP2023159297A (ja) | 2018-07-04 | 2023-08-22 | ジアリールピリジン誘導体の製造方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11999724B2 (enExample) |
| EP (1) | EP3819296B1 (enExample) |
| JP (2) | JP7337058B2 (enExample) |
| CN (1) | CN112368271A (enExample) |
| AU (1) | AU2019299152A1 (enExample) |
| CA (1) | CA3105328A1 (enExample) |
| ES (1) | ES2925365T3 (enExample) |
| IL (1) | IL279070B2 (enExample) |
| TW (1) | TWI840378B (enExample) |
| WO (1) | WO2020009132A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250019362A1 (en) | 2021-11-19 | 2025-01-16 | Nippon Soda Co., Ltd. | Method for producing 2-heteroarylpyridine compound |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY165215A (en) * | 2012-01-31 | 2018-03-09 | Daiichi Sankyo Co Ltd | Pyridone derivatives |
| TWI690525B (zh) | 2014-07-07 | 2020-04-11 | 日商第一三共股份有限公司 | 具有四氫吡喃基甲基之吡啶酮衍生物及其用途 |
| TWI796326B (zh) | 2017-03-24 | 2023-03-21 | 日商第一三共股份有限公司 | 含有ａｘｌ抑制劑與ｅｇｆｒ酪胺酸激酶抑制藥的醫藥品及其用途 |
-
2019
- 2019-07-01 TW TW108123125A patent/TWI840378B/zh not_active IP Right Cessation
- 2019-07-03 CN CN201980043226.0A patent/CN112368271A/zh active Pending
- 2019-07-03 US US17/252,469 patent/US11999724B2/en active Active
- 2019-07-03 CA CA3105328A patent/CA3105328A1/en active Pending
- 2019-07-03 EP EP19831009.6A patent/EP3819296B1/en active Active
- 2019-07-03 AU AU2019299152A patent/AU2019299152A1/en not_active Abandoned
- 2019-07-03 ES ES19831009T patent/ES2925365T3/es active Active
- 2019-07-03 IL IL279070A patent/IL279070B2/en unknown
- 2019-07-03 JP JP2020529019A patent/JP7337058B2/ja active Active
- 2019-07-03 WO PCT/JP2019/026395 patent/WO2020009132A1/ja not_active Ceased
-
2023
- 2023-08-22 JP JP2023134392A patent/JP2023159297A/ja active Pending
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