CA3105328A1 - Method for producing diarylpyridine derivatives - Google Patents

Method for producing diarylpyridine derivatives Download PDF

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Publication number
CA3105328A1
CA3105328A1 CA3105328A CA3105328A CA3105328A1 CA 3105328 A1 CA3105328 A1 CA 3105328A1 CA 3105328 A CA3105328 A CA 3105328A CA 3105328 A CA3105328 A CA 3105328A CA 3105328 A1 CA3105328 A1 CA 3105328A1
Authority
CA
Canada
Prior art keywords
formula
added
contents
compound represented
stirred
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3105328A
Other languages
English (en)
French (fr)
Inventor
Yuichi Aki
Fumihiko Toriyama
Natsuki Sakurai
Ai Kameda
Tomokazu OGURA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of CA3105328A1 publication Critical patent/CA3105328A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/121,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00Other general methods
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3105328A 2018-07-04 2019-07-03 Method for producing diarylpyridine derivatives Pending CA3105328A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018-127197 2018-07-04
JP2018127197 2018-07-04
PCT/JP2019/026395 WO2020009132A1 (ja) 2018-07-04 2019-07-03 ジアリールピリジン誘導体の製造方法

Publications (1)

Publication Number Publication Date
CA3105328A1 true CA3105328A1 (en) 2020-01-09

Family

ID=69059540

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3105328A Pending CA3105328A1 (en) 2018-07-04 2019-07-03 Method for producing diarylpyridine derivatives

Country Status (10)

Country Link
US (1) US11999724B2 (enExample)
EP (1) EP3819296B1 (enExample)
JP (2) JP7337058B2 (enExample)
CN (1) CN112368271A (enExample)
AU (1) AU2019299152A1 (enExample)
CA (1) CA3105328A1 (enExample)
ES (1) ES2925365T3 (enExample)
IL (1) IL279070B2 (enExample)
TW (1) TWI840378B (enExample)
WO (1) WO2020009132A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250019362A1 (en) 2021-11-19 2025-01-16 Nippon Soda Co., Ltd. Method for producing 2-heteroarylpyridine compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY165215A (en) * 2012-01-31 2018-03-09 Daiichi Sankyo Co Ltd Pyridone derivatives
TWI690525B (zh) 2014-07-07 2020-04-11 日商第一三共股份有限公司 具有四氫吡喃基甲基之吡啶酮衍生物及其用途
TWI796326B (zh) 2017-03-24 2023-03-21 日商第一三共股份有限公司 含有axl抑制劑與egfr酪胺酸激酶抑制藥的醫藥品及其用途

Also Published As

Publication number Publication date
WO2020009132A1 (ja) 2020-01-09
EP3819296A4 (en) 2021-06-09
ES2925365T3 (es) 2022-10-17
AU2019299152A1 (en) 2021-03-04
EP3819296A1 (en) 2021-05-12
JPWO2020009132A1 (ja) 2021-07-08
CN112368271A (zh) 2021-02-12
EP3819296B1 (en) 2022-06-29
IL279070B2 (en) 2024-05-01
TW202005962A (zh) 2020-02-01
US20210188823A1 (en) 2021-06-24
JP7337058B2 (ja) 2023-09-01
US11999724B2 (en) 2024-06-04
IL279070A (en) 2021-01-31
JP2023159297A (ja) 2023-10-31
IL279070B1 (en) 2024-01-01
TWI840378B (zh) 2024-05-01
AU2019299152A2 (en) 2021-03-11

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220923

B12 Application deemed to be withdrawn, abandoned or lapsed

Free format text: ST27 STATUS EVENT CODE: N-2-6-B10-B12-B303 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DEEMED ABANDONED - FAILURE TO RESPOND TO AN EXAMINER'S REQUISITION

Effective date: 20240807