JPWO2019180051A5 - - Google Patents
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- Publication number
- JPWO2019180051A5 JPWO2019180051A5 JP2020550823A JP2020550823A JPWO2019180051A5 JP WO2019180051 A5 JPWO2019180051 A5 JP WO2019180051A5 JP 2020550823 A JP2020550823 A JP 2020550823A JP 2020550823 A JP2020550823 A JP 2020550823A JP WO2019180051 A5 JPWO2019180051 A5 JP WO2019180051A5
- Authority
- JP
- Japan
- Prior art keywords
- bacterial strain
- cell
- composition
- composition according
- heterologous antigens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000001580 bacterial Effects 0.000 claims 6
- 239000000427 antigen Substances 0.000 claims 4
- 102000038129 antigens Human genes 0.000 claims 4
- 108091007172 antigens Proteins 0.000 claims 4
- 229960005486 vaccines Drugs 0.000 claims 3
- 229920001670 16S ribosomal RNA Polymers 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 241000194033 Enterococcus Species 0.000 claims 1
- 241000194030 Enterococcus gallinarum Species 0.000 claims 1
- 210000000987 Immune System Anatomy 0.000 claims 1
- 102000003777 Interleukin-1 beta Human genes 0.000 claims 1
- 108090000193 Interleukin-1 beta Proteins 0.000 claims 1
- 108010065637 Interleukin-23 Proteins 0.000 claims 1
- 108090001005 Interleukin-6 Proteins 0.000 claims 1
- 108090001007 Interleukin-8 Proteins 0.000 claims 1
- 108010057466 NF-kappa B Proteins 0.000 claims 1
- 102100002692 NFKB1 Human genes 0.000 claims 1
- 102100009534 TNF Human genes 0.000 claims 1
- 108010001801 Tumor Necrosis Factor-alpha Proteins 0.000 claims 1
- 230000000240 adjuvant Effects 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 238000002659 cell therapy Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002708 enhancing Effects 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000000546 pharmaceutic aid Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 230000004936 stimulating Effects 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
- 230000001225 therapeutic Effects 0.000 claims 1
Applications Claiming Priority (27)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1804384.4 | 2018-03-19 | ||
| GBGB1804384.4A GB201804384D0 (en) | 2018-03-19 | 2018-03-19 | Compositions |
| GB1809953.1 | 2018-06-18 | ||
| GBGB1809953.1A GB201809953D0 (en) | 2018-06-18 | 2018-06-18 | Compositions |
| EP18178350.7 | 2018-06-18 | ||
| EP18178350 | 2018-06-18 | ||
| GB1811900.8 | 2018-07-20 | ||
| GBGB1811900.8A GB201811900D0 (en) | 2018-07-20 | 2018-07-20 | Compositions comprising bacterial strains |
| GB1812378.6 | 2018-07-30 | ||
| GBGB1812378.6A GB201812378D0 (en) | 2018-07-30 | 2018-07-30 | Compositions comprising bacterial strains |
| GB1813444.5 | 2018-08-17 | ||
| GBGB1813444.5A GB201813444D0 (en) | 2018-08-17 | 2018-08-17 | Compositions |
| GBGB1813423.9A GB201813423D0 (en) | 2018-08-17 | 2018-08-17 | Compositions comprising bacterial strains |
| GB1813423.9 | 2018-08-17 | ||
| GBGB1816834.4A GB201816834D0 (en) | 2018-10-16 | 2018-10-16 | Compositions |
| GB1816834.4 | 2018-10-16 | ||
| GB1817641.2 | 2018-10-29 | ||
| GBGB1817641.2A GB201817641D0 (en) | 2018-10-29 | 2018-10-29 | Compositions comprising bacterial strains |
| GB1901199.8 | 2019-01-29 | ||
| GB1901218.6 | 2019-01-29 | ||
| GBGB1901199.8A GB201901199D0 (en) | 2019-01-29 | 2019-01-29 | Compositions comprising bacterial strains |
| GBGB1901218.6A GB201901218D0 (en) | 2019-01-29 | 2019-01-29 | Compositions |
| GBGB1901993.4A GB201901993D0 (en) | 2019-02-13 | 2019-02-13 | Compositions |
| GB1901993.4 | 2019-02-13 | ||
| GB1901992.6 | 2019-02-13 | ||
| GBGB1901992.6A GB201901992D0 (en) | 2019-02-13 | 2019-02-13 | Compositions comprising bacterial strains |
| PCT/EP2019/056894 WO2019180051A1 (en) | 2018-03-19 | 2019-03-19 | Compositions comprising bacterial strains |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021518414A JP2021518414A (ja) | 2021-08-02 |
| JPWO2019180051A5 true JPWO2019180051A5 (zh) | 2022-03-18 |
Family
ID=65955185
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550598A Pending JP2021518129A (ja) | 2018-03-19 | 2019-03-19 | 組成物 |
| JP2020550823A Pending JP2021518414A (ja) | 2018-03-19 | 2019-03-19 | 細菌株を含む組成物 |
| JP2023072015A Pending JP2023100747A (ja) | 2018-03-19 | 2023-04-26 | 組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550598A Pending JP2021518129A (ja) | 2018-03-19 | 2019-03-19 | 組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023072015A Pending JP2023100747A (ja) | 2018-03-19 | 2023-04-26 | 組成物 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US11419931B2 (zh) |
| EP (3) | EP3768284B1 (zh) |
| JP (3) | JP2021518129A (zh) |
| KR (2) | KR102578117B1 (zh) |
| CN (2) | CN112004543A (zh) |
| AU (2) | AU2019238358A1 (zh) |
| BR (2) | BR112020018818A2 (zh) |
| CA (2) | CA3094139A1 (zh) |
| CY (1) | CY1125104T1 (zh) |
| DK (1) | DK3768284T3 (zh) |
| ES (1) | ES2908826T3 (zh) |
| HR (1) | HRP20220368T1 (zh) |
| HU (1) | HUE058151T2 (zh) |
| IL (2) | IL277421B (zh) |
| LT (1) | LT3768284T (zh) |
| MA (1) | MA52128A (zh) |
| MD (1) | MD3768284T2 (zh) |
| MX (2) | MX2020009736A (zh) |
| PL (1) | PL3768284T3 (zh) |
| RS (1) | RS63090B1 (zh) |
| SG (2) | SG11202009259VA (zh) |
| SI (1) | SI3768284T1 (zh) |
| TW (2) | TW202003000A (zh) |
| WO (2) | WO2019180000A1 (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019180000A1 (en) | 2018-03-19 | 2019-09-26 | 4D Pharma Research Limited | Compositions |
| WO2021113500A2 (en) * | 2019-12-03 | 2021-06-10 | Board Of Regents, The University Of Texas System | Combination therapies for the treatment of cancer |
| WO2021252632A2 (en) * | 2020-06-09 | 2021-12-16 | Flagship Pioneering, Inc. | Physiologically acceptable compositions containing microorganisms or microbial products |
| US20230111960A1 (en) * | 2021-10-08 | 2023-04-13 | Iowa State University Research Foundation, Inc. | Use of dopamine producing products to increase vaccine efficacy |
| CN113999923B (zh) * | 2021-11-25 | 2024-05-14 | 上海金翌生物科技有限公司 | 小柳-原田综合症标志微生物及其应用 |
| CN115287243B (zh) * | 2022-04-15 | 2023-06-06 | 集美大学 | 一株变形假单胞菌flgK基因沉默菌株及其构建方法 |
| WO2024096122A1 (ja) * | 2022-11-04 | 2024-05-10 | 株式会社バイオパレット | Ｔｏｌｌ－Ｌｉｋｅ Ｒｅｃｅｐｔｏｒ ５（ＴＬＲ５）の活性化能を調節する微生物およびその生産方法 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US5132418A (en) | 1980-02-29 | 1992-07-21 | University Patents, Inc. | Process for preparing polynucleotides |
| US4500707A (en) | 1980-02-29 | 1985-02-19 | University Patents, Inc. | Nucleosides useful in the preparation of polynucleotides |
| US4973679A (en) | 1981-03-27 | 1990-11-27 | University Patents, Inc. | Process for oligonucleo tide synthesis using phosphormidite intermediates |
| US4668777A (en) | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
| US4373071A (en) | 1981-04-30 | 1983-02-08 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
| US5153319A (en) | 1986-03-31 | 1992-10-06 | University Patents, Inc. | Process for preparing polynucleotides |
| US5262530A (en) | 1988-12-21 | 1993-11-16 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
| US5047524A (en) | 1988-12-21 | 1991-09-10 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
| JPH08259450A (ja) | 1995-03-17 | 1996-10-08 | Nichinichi Seiyaku Kk | インターフェロン産生増強剤 |
| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| EP0904784A1 (en) | 1997-09-22 | 1999-03-31 | N.V. Nutricia | Probiotic nutritional preparation |
| GB0127916D0 (en) | 2001-11-21 | 2002-01-16 | Rowett Res Inst | Method |
| US20040009937A1 (en) * | 2002-01-31 | 2004-01-15 | Wei Chen | Methods and composition for delivering nucleic acids and/or proteins to the respiratory system |
| US20080025977A1 (en) | 2003-04-14 | 2008-01-31 | Arius Research, Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD59 |
| US20060228369A1 (en) | 2005-04-11 | 2006-10-12 | Program For Appropriate Technology In Health | Stabilization and preservation of temperature-sensitive vaccines |
| JP2007116991A (ja) | 2005-10-28 | 2007-05-17 | Eternal Light General Institute Inc | 機能性食品 |
| ES2895666T3 (es) | 2006-10-27 | 2022-02-22 | Capsugel Belgium Nv | Cápsulas duras de hidroxipropilmetilcelulosa y proceso de fabricación |
| EP1958647A1 (en) | 2007-02-15 | 2008-08-20 | Helmholtz-Zentrum für Infektionsforschung GmbH | Pharmaceutical composition with bacteria for tumor treatment |
| US8758760B2 (en) | 2007-03-19 | 2014-06-24 | Morishita Jintan Co., Ltd. | Oral vaccine |
| US20090297552A1 (en) * | 2008-04-25 | 2009-12-03 | Aderem Alan A | Flagellin polypeptide vaccines |
| ES2457518T3 (es) * | 2009-10-06 | 2014-04-28 | Panacela Labs, Inc. | Uso de receptores semejantes a Toll y agonista para tratar cáncer |
| AU2012205681B2 (en) | 2011-01-10 | 2016-07-28 | Cleveland Biolabs, Inc. | Use of toll-like receptor agonist for treating cancer |
| EP2731572B1 (en) | 2011-07-13 | 2021-04-07 | Pharmaxis Ltd. | Improvements relating to delivery devices |
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| ES2408279B1 (es) | 2011-12-15 | 2014-09-09 | Universidad De Las Palmas De Gran Canaria | Bacteria acido láctica probiótica |
| FR2989002B1 (fr) | 2012-04-10 | 2015-05-15 | Beepratte Lab | Compositions a base de probiotiques et d'un complexe beepollen/argile, leur preparation et leurs utilisations en nutrition et therapeutique |
| WO2014043593A2 (en) | 2012-09-13 | 2014-03-20 | Massachusetts Institute Of Technology | Programmable drug delivery profiles of tumor-targeted bacteria |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| WO2015121863A1 (en) * | 2014-02-12 | 2015-08-20 | Transalgae Israel Ltd. | Algal based edible vaccines |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520502D0 (en) * | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| MA41013B1 (fr) | 2015-11-20 | 2018-07-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MA41708A (fr) * | 2017-05-24 | 2020-04-08 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| AU2018298087A1 (en) | 2017-07-05 | 2020-01-23 | Evelo Biosciences, Inc. | Compositions and methods of treating cancer using bifidobacterium animalis ssp. lactis |
| KR20200038970A (ko) * | 2017-08-10 | 2020-04-14 | 4디 파마 리서치 리미티드 | 박테리아 균주를 포함하는 조성물 |
| WO2019180000A1 (en) | 2018-03-19 | 2019-09-26 | 4D Pharma Research Limited | Compositions |
-
2019
- 2019-03-19 WO PCT/EP2019/056809 patent/WO2019180000A1/en active Search and Examination
- 2019-03-19 CN CN201980026687.7A patent/CN112004543A/zh active Pending
- 2019-03-19 MD MDE20210096T patent/MD3768284T2/ro unknown
- 2019-03-19 AU AU2019238358A patent/AU2019238358A1/en not_active Abandoned
- 2019-03-19 AU AU2019239048A patent/AU2019239048B2/en active Active
- 2019-03-19 ES ES19714132T patent/ES2908826T3/es active Active
- 2019-03-19 BR BR112020018818-2A patent/BR112020018818A2/pt not_active IP Right Cessation
- 2019-03-19 HU HUE19714132A patent/HUE058151T2/hu unknown
- 2019-03-19 MX MX2020009736A patent/MX2020009736A/es unknown
- 2019-03-19 PL PL19714132T patent/PL3768284T3/pl unknown
- 2019-03-19 WO PCT/EP2019/056894 patent/WO2019180051A1/en unknown
- 2019-03-19 CN CN201980020532.2A patent/CN111886018A/zh active Pending
- 2019-03-19 EP EP19714132.8A patent/EP3768284B1/en active Active
- 2019-03-19 CA CA3094139A patent/CA3094139A1/en not_active Abandoned
- 2019-03-19 KR KR1020207029431A patent/KR102578117B1/ko active IP Right Grant
- 2019-03-19 SG SG11202009259VA patent/SG11202009259VA/en unknown
- 2019-03-19 HR HRP20220368TT patent/HRP20220368T1/hr unknown
- 2019-03-19 KR KR1020207028232A patent/KR20210003096A/ko unknown
- 2019-03-19 EP EP22150203.2A patent/EP4046644A1/en active Pending
- 2019-03-19 SG SG11202009254YA patent/SG11202009254YA/en unknown
- 2019-03-19 SI SI201930190T patent/SI3768284T1/sl unknown
- 2019-03-19 JP JP2020550598A patent/JP2021518129A/ja active Pending
- 2019-03-19 BR BR112020019008-0A patent/BR112020019008A2/pt not_active Application Discontinuation
- 2019-03-19 TW TW108109387A patent/TW202003000A/zh unknown
- 2019-03-19 RS RS20220288A patent/RS63090B1/sr unknown
- 2019-03-19 JP JP2020550823A patent/JP2021518414A/ja active Pending
- 2019-03-19 LT LTEPPCT/EP2019/056809T patent/LT3768284T/lt unknown
- 2019-03-19 MX MX2020009733A patent/MX2020009733A/es unknown
- 2019-03-19 TW TW108109417A patent/TW202003001A/zh unknown
- 2019-03-19 DK DK19714132.8T patent/DK3768284T3/da active
- 2019-03-19 MA MA052128A patent/MA52128A/fr unknown
- 2019-03-19 EP EP19714136.9A patent/EP3768285A1/en active Pending
- 2019-03-19 CA CA3094297A patent/CA3094297A1/en active Pending
-
2020
- 2020-09-16 IL IL277421A patent/IL277421B/en unknown
- 2020-09-16 IL IL277422A patent/IL277422A/en unknown
- 2020-09-17 US US17/024,628 patent/US11419931B2/en active Active
- 2020-09-18 US US17/025,706 patent/US11857614B2/en active Active
-
2022
- 2022-02-24 US US17/679,243 patent/US20220257745A1/en not_active Abandoned
- 2022-03-23 CY CY20221100232T patent/CY1125104T1/el unknown
-
2023
- 2023-04-26 JP JP2023072015A patent/JP2023100747A/ja active Pending
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