JPWO2019178085A5 - - Google Patents

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Publication number
JPWO2019178085A5
JPWO2019178085A5 JP2020549002A JP2020549002A JPWO2019178085A5 JP WO2019178085 A5 JPWO2019178085 A5 JP WO2019178085A5 JP 2020549002 A JP2020549002 A JP 2020549002A JP 2020549002 A JP2020549002 A JP 2020549002A JP WO2019178085 A5 JPWO2019178085 A5 JP WO2019178085A5
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Japan
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cell
nucleic acid
cells
amino acid
composition
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JP2020549002A
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English (en)
Japanese (ja)
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JP2021518111A5 (https=
JP7314161B2 (ja
JP2021518111A (ja
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Priority claimed from PCT/US2019/021833 external-priority patent/WO2019178085A1/en
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Publication of JPWO2019178085A5 publication Critical patent/JPWO2019178085A5/ja
Publication of JP2021518111A5 publication Critical patent/JP2021518111A5/ja
Priority to JP2023114641A priority Critical patent/JP7696958B2/ja
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JP2020549002A 2018-03-14 2019-03-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法 Active JP7314161B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023114641A JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862643139P 2018-03-14 2018-03-14
US62/643,139 2018-03-14
PCT/US2019/021833 WO2019178085A1 (en) 2018-03-14 2019-03-12 Il-13 receptor alpha 2 targeted, zetakine directed t cell immunotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023114641A Division JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Publications (4)

Publication Number Publication Date
JP2021518111A JP2021518111A (ja) 2021-08-02
JPWO2019178085A5 true JPWO2019178085A5 (https=) 2022-03-18
JP2021518111A5 JP2021518111A5 (https=) 2022-03-18
JP7314161B2 JP7314161B2 (ja) 2023-07-25

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ID=67907266

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020549002A Active JP7314161B2 (ja) 2018-03-14 2019-03-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法
JP2023114641A Active JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023114641A Active JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Country Status (13)

Country Link
US (1) US12606603B2 (https=)
EP (2) EP4491718A3 (https=)
JP (2) JP7314161B2 (https=)
KR (2) KR20260021083A (https=)
CN (1) CN112088165A (https=)
AU (2) AU2019234580B2 (https=)
BR (1) BR112020018534A2 (https=)
CA (1) CA3093791A1 (https=)
EA (1) EA202091984A1 (https=)
IL (1) IL277268A (https=)
MX (2) MX2020009464A (https=)
SG (1) SG11202008926RA (https=)
WO (1) WO2019178085A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019178078A1 (en) 2018-03-14 2019-09-19 Seattle Children's Hospital (dba Seattle Children's Research Institute) Il-13 receptor alpha 2 (il13ra2) chimeric antigen receptor for tumor specific t cell immunotherapy
CN119654345A (zh) * 2022-08-25 2025-03-18 南京传奇生物科技有限公司 靶向白介素13受体亚基α2的嵌合抗原受体及其使用方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090257994A1 (en) * 2001-04-30 2009-10-15 City Of Hope Chimeric immunoreceptor useful in treating human cancers
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
EP2220117A2 (en) 2007-11-30 2010-08-25 Kalobios Pharmaceuticals, Inc. Antibodies to the pcrv antigen of pseudomonas aeruginosa
EP4032552B1 (en) 2008-08-26 2023-10-04 City of Hope Method and compositions for enhanced anti-tumor effector functioning of t cells
DK2496698T3 (en) * 2009-11-03 2019-04-15 Hope City TRUNCATED EPIDERIMAL GROWTH FACTOR RECEPTOR (EGFRt) FOR TRUNCATED T-CELL SELECTION
JP6850528B2 (ja) 2012-02-13 2021-03-31 シアトル チルドレンズ ホスピタル ドゥーイング ビジネス アズ シアトル チルドレンズ リサーチ インスティテュート 二重特異性キメラ抗原受容体およびその治療的使用
CA2881981A1 (en) 2012-08-20 2014-02-27 Fred Hutchinson Cancer Research Center Method and compositions for cellular immunotherapy
CN104936621A (zh) 2012-11-07 2015-09-23 辉瑞公司 抗IL-13受体α2抗体和抗体-药物缀合物
JP6345688B2 (ja) 2012-12-05 2018-06-20 ソラ・バイオサイエンシズ・エルエルシー タンパク質発現増強ポリペプチド
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
EP3783098A1 (en) * 2013-05-14 2021-02-24 Board Of Regents, The University Of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
TWI805109B (zh) 2014-08-28 2023-06-11 美商奇諾治療有限公司 對cd19具專一性之抗體及嵌合抗原受體
CN107002084B (zh) * 2014-09-19 2021-09-10 希望之城公司 靶向IL13Rα2的共刺激嵌合抗原受体T细胞
JP7264592B2 (ja) 2015-01-26 2023-04-25 ザ ユニバーシティー オブ シカゴ IL13Rα2結合剤及び癌治療におけるその使用
EP3324984A4 (en) 2015-07-21 2019-03-27 City of Hope T-LYMPHOCYTES FOR THE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS
JP6905163B2 (ja) * 2015-09-03 2021-07-21 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア サイトカイン放出症候群を予測するバイオマーカー
ES2879700T3 (es) * 2016-02-05 2021-11-22 Hope City Administración de células T genomanipuladas para el tratamiento de cánceres en el sistema nervioso central
WO2017172981A2 (en) 2016-03-29 2017-10-05 University Of Southern California Chimeric antigen receptors targeting cancer
MX2018014950A (es) 2016-06-07 2019-04-25 Macrogenics Inc Terapia de combinacion.
MA45779A (fr) * 2016-07-29 2019-06-05 Juno Therapeutics Inc Polypeptides immunomdulateurs et compositions et procédés associés
JP2019530440A (ja) * 2016-09-02 2019-10-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア インターロイキン6受容体α結合単鎖可変断片を含む方法および組成物
WO2018156711A1 (en) 2017-02-22 2018-08-30 H. Lee Moffitt Cancer Center And Research Institute, Inc. Il13ra2-binding chimeric antigen receptors
WO2019178078A1 (en) 2018-03-14 2019-09-19 Seattle Children's Hospital (dba Seattle Children's Research Institute) Il-13 receptor alpha 2 (il13ra2) chimeric antigen receptor for tumor specific t cell immunotherapy

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