JP2021518111A5 - - Google Patents

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Publication number
JP2021518111A5
JP2021518111A5 JP2020549002A JP2020549002A JP2021518111A5 JP 2021518111 A5 JP2021518111 A5 JP 2021518111A5 JP 2020549002 A JP2020549002 A JP 2020549002A JP 2020549002 A JP2020549002 A JP 2020549002A JP 2021518111 A5 JP2021518111 A5 JP 2021518111A5
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JP
Japan
Prior art keywords
cells
nucleic acid
cell
amino acid
cancer
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Granted
Application number
JP2020549002A
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English (en)
Japanese (ja)
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JP2021518111A (ja
JP7314161B2 (ja
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Priority claimed from PCT/US2019/021833 external-priority patent/WO2019178085A1/en
Publication of JP2021518111A publication Critical patent/JP2021518111A/ja
Publication of JP2021518111A5 publication Critical patent/JP2021518111A5/ja
Priority to JP2023114641A priority Critical patent/JP7696958B2/ja
Application granted granted Critical
Publication of JP7314161B2 publication Critical patent/JP7314161B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020549002A 2018-03-14 2019-03-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法 Active JP7314161B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023114641A JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862643139P 2018-03-14 2018-03-14
US62/643,139 2018-03-14
PCT/US2019/021833 WO2019178085A1 (en) 2018-03-14 2019-03-12 Il-13 receptor alpha 2 targeted, zetakine directed t cell immunotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023114641A Division JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Publications (3)

Publication Number Publication Date
JP2021518111A JP2021518111A (ja) 2021-08-02
JP2021518111A5 true JP2021518111A5 (https=) 2022-03-18
JP7314161B2 JP7314161B2 (ja) 2023-07-25

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ID=67907266

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020549002A Active JP7314161B2 (ja) 2018-03-14 2019-03-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法
JP2023114641A Active JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Family Applications After (1)

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JP2023114641A Active JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Country Status (13)

Country Link
US (1) US12606603B2 (https=)
EP (2) EP4491718A3 (https=)
JP (2) JP7314161B2 (https=)
KR (2) KR102917671B1 (https=)
CN (1) CN112088165A (https=)
AU (2) AU2019234580B2 (https=)
BR (1) BR112020018534A2 (https=)
CA (1) CA3093791A1 (https=)
EA (1) EA202091984A1 (https=)
IL (1) IL277268A (https=)
MX (2) MX2020009464A (https=)
SG (1) SG11202008926RA (https=)
WO (1) WO2019178085A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3765041A4 (en) 2018-03-14 2021-12-22 Seattle Children's Hospital (DBA Seattle Children's Research Institute) IL-13 CHIMERIC RECEPTOR ALPHA 2 (IL13RA2) ANTIGEN RECEPTOR FOR T-CELL T-CELL IMMUNOTHERAPY
EP4577575A1 (en) * 2022-08-25 2025-07-02 Nanjing Legend Biotech Co., Ltd. Chimeric antigen receptors targeting interleukin 13 receptor subunit alpha 2 and methods of use thereof

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US20090257994A1 (en) * 2001-04-30 2009-10-15 City Of Hope Chimeric immunoreceptor useful in treating human cancers
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
BRPI0819598A2 (pt) 2007-11-30 2017-05-09 Kalobios Pharmaceuticals Inc anticorpos para o antígeno pcrv da pseudomonas aeruginosa
EP2331566B1 (en) 2008-08-26 2015-10-07 City of Hope Method and compositions for enhanced anti-tumor effector functioning of t cells
TR201904484T4 (tr) 2009-11-03 2019-05-21 Hope City Transdüse T hücre seçimine yönelik kesik epiderimal büyüme faktörü reseptörü (EGFRt).
CA2861491C (en) 2012-02-13 2020-08-25 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
BR122020002986A8 (pt) 2012-08-20 2023-04-18 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Método e composições para imunoterapia celular
KR101763499B1 (ko) 2012-11-07 2017-07-31 화이자 인코포레이티드 항-il-13 수용체 알파 2 항체 및 항체-약물 접합체
US9758807B2 (en) 2012-12-05 2017-09-12 SOLA Biosciences, LLC Protein expression enhancing polypeptides
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
EP3783098A1 (en) 2013-05-14 2021-02-24 Board Of Regents, The University Of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
TWI751102B (zh) 2014-08-28 2022-01-01 美商奇諾治療有限公司 對cd19具專一性之抗體及嵌合抗原受體
BR112017005631A2 (pt) 2014-09-19 2018-06-26 City Of Hope células t com receptor de antígeno coestimulador quimérico direcionadas à il13ra2
CN107683289B (zh) 2015-01-26 2021-08-06 芝加哥大学 IL13Rα2结合剂和其在癌症治疗中的用途
CA2992989A1 (en) 2015-07-21 2017-01-26 City Of Hope T cells for expression of chimeric antigen receptors and other receptors
WO2017040930A2 (en) * 2015-09-03 2017-03-09 The Trustees Of The University Of Pennsylvania Biomarkers predictive of cytokine release syndrome
IL287889B2 (en) * 2016-02-05 2024-03-01 Hope City Administration of engineered t cells for treatment of cancers in the central nervous system
KR20230148844A (ko) 2016-03-29 2023-10-25 유니버시티 오브 써던 캘리포니아 암을 표적하는 키메라 항원 수용체
MX2018014950A (es) 2016-06-07 2019-04-25 Macrogenics Inc Terapia de combinacion.
US12304935B2 (en) * 2016-07-29 2025-05-20 Juno Therapeutics, Inc. Immunomodulatory polypeptides and related compositions and methods
AU2017319702B2 (en) 2016-09-02 2024-11-14 The Regents Of The University Of California Methods and compositions involving interleukin-6 receptor alpha-binding single chain variable fragments
US12083148B2 (en) 2017-02-22 2024-09-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. IL13Ra2-binding chimeric antigen receptors
EP3765041A4 (en) 2018-03-14 2021-12-22 Seattle Children's Hospital (DBA Seattle Children's Research Institute) IL-13 CHIMERIC RECEPTOR ALPHA 2 (IL13RA2) ANTIGEN RECEPTOR FOR T-CELL T-CELL IMMUNOTHERAPY

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