JPS6429399A - Method for separating human lymphotoxin - Google Patents
Method for separating human lymphotoxinInfo
- Publication number
- JPS6429399A JPS6429399A JP18496987A JP18496987A JPS6429399A JP S6429399 A JPS6429399 A JP S6429399A JP 18496987 A JP18496987 A JP 18496987A JP 18496987 A JP18496987 A JP 18496987A JP S6429399 A JPS6429399 A JP S6429399A
- Authority
- JP
- Japan
- Prior art keywords
- human lymphotoxin
- lymphotoxin
- adsorbed
- sulfate
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE:To separate the titled compound useful as an antitumor agent as a single component, by adsorbing a mixture consisting of human lymphotoxin and a partial hydrolyzate thereof on specific polysaccharides and desorbing the adsorbed lymphotoxin with an aqueous solution of an inorganic salt. CONSTITUTION:A mixture consisting of human lymphotoxin and a partial hydrolyzate thereof is adsorbed on water-insoluble polysaccharides (e.g. cellulose sulfate, agarose sulfate or crosslinked dextran sulfate) having linked sulfuric acid groups. The adsorbed human lymphotoxin is then desorbed with an aqueous solution of an inorganic salt to separate the aimed human lymphotoxin.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18496987A JPS6429399A (en) | 1987-07-24 | 1987-07-24 | Method for separating human lymphotoxin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18496987A JPS6429399A (en) | 1987-07-24 | 1987-07-24 | Method for separating human lymphotoxin |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6429399A true JPS6429399A (en) | 1989-01-31 |
Family
ID=16162521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18496987A Pending JPS6429399A (en) | 1987-07-24 | 1987-07-24 | Method for separating human lymphotoxin |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6429399A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0592989A2 (en) * | 1992-10-12 | 1994-04-20 | B. Braun Melsungen Ag | Process of the selective and quantitative removal or preparation of tumor necrosis factor (TNF) and/or lipopolysaccharides (LPS) of aqueous solutions |
-
1987
- 1987-07-24 JP JP18496987A patent/JPS6429399A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0592989A2 (en) * | 1992-10-12 | 1994-04-20 | B. Braun Melsungen Ag | Process of the selective and quantitative removal or preparation of tumor necrosis factor (TNF) and/or lipopolysaccharides (LPS) of aqueous solutions |
EP0592989A3 (en) * | 1992-10-12 | 1995-12-13 | Braun Melsungen Ag | Process of the selective and quantitative removal or preparation of tumor necrosis factor (tnf) and/or lipopolysaccharides (lps) of aqueous solutions |
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