JPS6420096A - Mutein and its production - Google Patents

Mutein and its production

Info

Publication number
JPS6420096A
JPS6420096A JP63058544A JP5854488A JPS6420096A JP S6420096 A JPS6420096 A JP S6420096A JP 63058544 A JP63058544 A JP 63058544A JP 5854488 A JP5854488 A JP 5854488A JP S6420096 A JPS6420096 A JP S6420096A
Authority
JP
Japan
Prior art keywords
interleukin
muteins
mutein
production
substitued
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63058544A
Other languages
English (en)
Inventor
Efu Maaku Debitsuto
Esu Rin Reo
Yu Ru Shida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27030446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS6420096(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of JPS6420096A publication Critical patent/JPS6420096A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP63058544A 1982-10-19 1988-03-14 Mutein and its production Pending JPS6420096A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43515482A 1982-10-19 1982-10-19
US48616283A 1983-04-15 1983-04-15

Publications (1)

Publication Number Publication Date
JPS6420096A true JPS6420096A (en) 1989-01-24

Family

ID=27030446

Family Applications (2)

Application Number Title Priority Date Filing Date
JP18730184A Granted JPS6128392A (ja) 1982-10-19 1984-09-08 変形されたインターフェロン―β及びその製造方法
JP63058544A Pending JPS6420096A (en) 1982-10-19 1988-03-14 Mutein and its production

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP18730184A Granted JPS6128392A (ja) 1982-10-19 1984-09-08 変形されたインターフェロン―β及びその製造方法

Country Status (23)

Country Link
EP (4) EP0192811B1 (ja)
JP (2) JPS6128392A (ja)
KR (1) KR910009900B1 (ja)
AT (4) ATE33503T1 (ja)
AU (1) AU563962B2 (ja)
BE (1) BE898016A (ja)
CA (1) CA1340861C (ja)
CH (1) CH669395A5 (ja)
DE (4) DE3382528D1 (ja)
DK (2) DK168767B1 (ja)
ES (4) ES8505717A1 (ja)
FI (1) FI82266C (ja)
FR (1) FR2534594B1 (ja)
GB (1) GB2130219B (ja)
GR (1) GR79408B (ja)
IE (1) IE56026B1 (ja)
IL (1) IL69970A (ja)
LU (3) LU88761I2 (ja)
NL (2) NL930119I2 (ja)
NO (1) NO173740C (ja)
NZ (1) NZ205922A (ja)
PH (2) PH20343A (ja)
PT (1) PT77512B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH069690A (ja) * 1991-07-01 1994-01-18 Quest Internatl Bv ラクトコッカスラクチス亜種ラクチス由来の新規のバクテリオシン
JP2007527242A (ja) * 2004-03-05 2007-09-27 カイロン コーポレーション 治療剤の患者耐容性を予測するためのインビトロ試験システム

Families Citing this family (116)

* Cited by examiner, † Cited by third party
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JP2008509651A (ja) * 2004-03-05 2008-04-03 カイロン コーポレーション 組み合わせのインターロイキン−２ムテイン

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FI833681A (fi) 1984-04-20
FR2534594A1 (fr) 1984-04-20
AU563962B2 (en) 1987-07-30
IE56026B1 (en) 1991-03-27
FI82266B (fi) 1990-10-31
PH20343A (en) 1986-12-04
JPH0568480B2 (ja) 1993-09-29
ATE33503T1 (de) 1988-04-15
IL69970A0 (en) 1984-01-31
NL930119I1 (nl) 1993-11-01
DK105892A (da) 1992-08-26
GR79408B (ja) 1984-10-22
EP0234599A1 (en) 1987-09-02
EP0192811A1 (en) 1986-09-03
CA1340861C (en) 1999-12-28
GB2130219A (en) 1984-05-31
ES8506089A1 (es) 1985-06-16
DK481383D0 (da) 1983-10-19
DE3376271D1 (en) 1988-05-19
CH669395A5 (ja) 1989-03-15
NO173740C (no) 1994-01-26
LU90413I2 (fr) 1999-09-07
FI82266C (fi) 1991-02-11
PT77512B (en) 1987-11-24
PT77512A (en) 1983-11-01
EP0234599B1 (en) 1992-03-11
NL960013I2 (nl) 1997-03-03
DE3380598D1 (en) 1989-10-26
BE898016A (fr) 1984-02-15
NO173740B (no) 1993-10-18
LU88761I2 (fr) 1996-11-05
PH23702A (en) 1989-09-27
EP0218825A1 (en) 1987-04-22
ES526541A0 (es) 1985-04-01
ATE61407T1 (de) 1991-03-15
LU88357I2 (fr) 1994-05-04
EP0218825B1 (en) 1989-09-20
AU2008683A (en) 1984-05-03
ATE73493T1 (de) 1992-03-15
ES533054A0 (es) 1985-08-01
NL930119I2 (nl) 1995-01-16
DK105892D0 (da) 1992-08-26
DE3382197D1 (de) 1991-04-11
KR910009900B1 (ko) 1991-12-03
NZ205922A (en) 1987-11-27
IL69970A (en) 1991-05-12
DK168767B1 (da) 1994-06-06
ES8506801A1 (es) 1985-08-01
GB2130219B (en) 1986-01-29
FR2534594B1 (fr) 1987-06-19
ES542829A0 (es) 1986-06-01
ES533053A0 (es) 1985-06-16
FI833681A0 (fi) 1983-10-10
JPS6128392A (ja) 1986-02-08
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DK481383A (da) 1984-04-20
EP0109748A1 (en) 1984-05-30
NO833793L (no) 1984-04-24
DK171681B1 (da) 1997-03-10
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IE832380L (en) 1984-04-19
EP0192811B1 (en) 1991-03-06
ES8608043A1 (es) 1986-06-01
DE3382528D1 (de) 1992-04-16
ES8505717A1 (es) 1985-04-01
ATE46539T1 (de) 1989-10-15
KR840006369A (ko) 1984-11-29
NL960013I1 (nl) 1996-10-01

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