JPS6357440B2 - - Google Patents
Info
- Publication number
- JPS6357440B2 JPS6357440B2 JP58195931A JP19593183A JPS6357440B2 JP S6357440 B2 JPS6357440 B2 JP S6357440B2 JP 58195931 A JP58195931 A JP 58195931A JP 19593183 A JP19593183 A JP 19593183A JP S6357440 B2 JPS6357440 B2 JP S6357440B2
- Authority
- JP
- Japan
- Prior art keywords
- interleukin
- ifn
- dna
- amino acid
- cysteine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43515482A | 1982-10-19 | 1982-10-19 | |
| US435154 | 1982-10-19 | ||
| US486162 | 1983-04-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5993093A JPS5993093A (ja) | 1984-05-29 |
| JPS6357440B2 true JPS6357440B2 (cs) | 1988-11-11 |
Family
ID=23727220
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58195931A Granted JPS5993093A (ja) | 1982-10-19 | 1983-10-19 | 変形されたインターロイキン―２及びその製造方法 |
| JP18730384A Granted JPS6128384A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
| JP18730484A Pending JPS6128394A (ja) | 1982-10-19 | 1984-09-08 | 部位特定突然変異用オリゴヌクレオチド |
| JP18730284A Granted JPS6128393A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP18730384A Granted JPS6128384A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
| JP18730484A Pending JPS6128394A (ja) | 1982-10-19 | 1984-09-08 | 部位特定突然変異用オリゴヌクレオチド |
| JP18730284A Granted JPS6128393A (ja) | 1982-10-19 | 1984-09-08 | 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 |
Country Status (4)
| Country | Link |
|---|---|
| JP (4) | JPS5993093A (cs) |
| IL (1) | IL90047A (cs) |
| IN (1) | IN161992B (cs) |
| ZA (1) | ZA837789B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL76360A0 (en) | 1984-09-26 | 1986-01-31 | Takeda Chemical Industries Ltd | Mutual separation of proteins |
| JP2675294B2 (ja) * | 1984-10-15 | 1997-11-12 | カイロン コーポレイション | ヒト腫瘍壊死因子 |
| EP0200748B1 (en) * | 1984-10-15 | 1991-02-06 | Cetus Corporation | Human tumor necrosis factor |
| US4572798A (en) * | 1984-12-06 | 1986-02-25 | Cetus Corporation | Method for promoting disulfide bond formation in recombinant proteins |
| JP2583753B2 (ja) * | 1984-12-21 | 1997-02-19 | 大塚製薬株式会社 | 抗腫瘍活性物質およびその製造法 |
| JP2721854B2 (ja) * | 1984-12-21 | 1998-03-04 | 大塚製薬株式会社 | 抗腫瘍活性物質 |
| PT82429B (pt) * | 1985-04-22 | 1988-03-03 | Genentech Inc | Novos mutantes do activador de plasmionogenio de tecido humano |
| US4818698A (en) * | 1985-08-23 | 1989-04-04 | Toyo Jozo Co., Ltd. | Polypeptides and preparation process thereof |
| NZ226543A (en) * | 1987-10-22 | 1992-02-25 | Merck & Co Inc | Recombinant mutant acidic fibroblast growth factor |
| DK0383599T3 (da) * | 1989-02-17 | 1996-08-05 | Merck & Co Inc | Protein-anticancermiddel |
| NZ232900A (en) * | 1989-03-22 | 1993-08-26 | Merck & Co Inc | Pseudomonas exotoxin a, pe 40 domain derivatives |
| US6207798B1 (en) | 1989-08-03 | 2001-03-27 | Merck & Co., Inc. | Modified PE40 toxin fusion proteins |
| JPH0751621A (ja) * | 1993-08-12 | 1995-02-28 | Kansei Kogyo Kk | 静電吸着による管内面更生工法 |
| UY27373A1 (es) * | 2001-07-09 | 2003-02-28 | Schering Ag | Formulaciones de interferón beta-humano |
| KR20060034286A (ko) * | 2003-07-11 | 2006-04-21 | 쉐링 악티엔게젤샤프트 | 개량된 재조합 인간 인터페론-베타-1ｂ 폴리펩티드 |
| WO2021221470A1 (ko) * | 2020-04-29 | 2021-11-04 | (주) 제노팜 | 인터페론-베타 변이체와 항체가 융합된 재조합 단백질 및 이를 포함하는 약학 조성물 |
-
1983
- 1983-10-14 IL IL90047A patent/IL90047A/xx not_active IP Right Cessation
- 1983-10-19 JP JP58195931A patent/JPS5993093A/ja active Granted
- 1983-10-19 IN IN1282/CAL/83A patent/IN161992B/en unknown
- 1983-10-19 ZA ZA837789A patent/ZA837789B/xx unknown
-
1984
- 1984-09-08 JP JP18730384A patent/JPS6128384A/ja active Granted
- 1984-09-08 JP JP18730484A patent/JPS6128394A/ja active Pending
- 1984-09-08 JP JP18730284A patent/JPS6128393A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6128394A (ja) | 1986-02-08 |
| JPH0380475B2 (cs) | 1991-12-25 |
| IL90047A (en) | 1992-12-01 |
| JPS6128384A (ja) | 1986-02-08 |
| IN161992B (cs) | 1988-03-12 |
| JPS6128393A (ja) | 1986-02-08 |
| JPH057996B2 (cs) | 1993-01-29 |
| JPS5993093A (ja) | 1984-05-29 |
| ZA837789B (en) | 1984-11-28 |
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