JPS6353823B2 - - Google Patents
Info
- Publication number
- JPS6353823B2 JPS6353823B2 JP56133224A JP13322481A JPS6353823B2 JP S6353823 B2 JPS6353823 B2 JP S6353823B2 JP 56133224 A JP56133224 A JP 56133224A JP 13322481 A JP13322481 A JP 13322481A JP S6353823 B2 JPS6353823 B2 JP S6353823B2
- Authority
- JP
- Japan
- Prior art keywords
- contents
- container
- final container
- magnetic material
- freeze
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 claims description 12
- 239000000696 magnetic material Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 8
- 108090000623 proteins and genes Proteins 0.000 claims description 8
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims description 5
- 229910001220 stainless steel Inorganic materials 0.000 claims description 5
- 239000010935 stainless steel Substances 0.000 claims description 5
- 102000003839 Human Proteins Human genes 0.000 claims description 4
- 108090000144 Human Proteins Proteins 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 4
- 238000004090 dissolution Methods 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 2
- 230000001737 promoting effect Effects 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims 1
- 238000009472 formulation Methods 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 239000006260 foam Substances 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 2
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 1
- 102000008946 Fibrinogen Human genes 0.000 description 1
- 108010049003 Fibrinogen Proteins 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000012738 dissolution medium Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000001516 effect on protein Effects 0.000 description 1
- 229940012952 fibrinogen Drugs 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F21/00—Dissolving
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/90—Heating or cooling systems
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0428980A AT371719B (de) | 1980-08-25 | 1980-08-25 | Verfahren und vorrichtung zur beschleunigung des aufloesens von schwerloeslichen lyophilisierten arzneimitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5789863A JPS5789863A (en) | 1982-06-04 |
| JPS6353823B2 true JPS6353823B2 (enrdf_load_stackoverflow) | 1988-10-25 |
Family
ID=3562079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56133224A Granted JPS5789863A (en) | 1980-08-25 | 1981-08-24 | Method for promoting dissolution of hardly soluble freeze dried drug |
Country Status (14)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3308892A1 (de) * | 1983-03-12 | 1984-09-13 | Vereinigte Aluminium-Werke AG, 1000 Berlin und 5300 Bonn | Heizbarer magnetruehrer fuer hochtemperaturaufschluesse |
| DE3439654C2 (de) * | 1984-10-30 | 1987-02-26 | Brauerei Beck GmbH & Co, 2800 Bremen | Vorrichtung zum gleichmäßigen Verteilen von Hefeteilchen in hefehaltigem Bier |
| AT382783B (de) * | 1985-06-20 | 1987-04-10 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes |
| AT397203B (de) * | 1988-05-31 | 1994-02-25 | Immuno Ag | Gewebeklebstoff |
| DE4017868A1 (de) * | 1990-06-02 | 1990-10-31 | Siegfried Dipl Phys Stiller | Mischkammer zur verduennung und haemolyse von blut |
| JPH06312009A (ja) * | 1993-04-28 | 1994-11-08 | Daiichi Rajio Isotope Kenkyusho:Kk | 放射性医薬品加熱装置 |
| DE4406217C2 (de) * | 1994-02-25 | 1997-04-17 | Janke & Kunkel Kg | Magnetrührer mit einem Gehäuse |
| US5529391A (en) * | 1994-09-22 | 1996-06-25 | Duke University | Magnetic stirring and heating/cooling apparatus |
| US5549382A (en) * | 1995-04-27 | 1996-08-27 | Correia, Ii; Bernard A. | Stirrer for food preparation |
| DE19617369A1 (de) * | 1996-04-30 | 1997-11-06 | Immuno Ag | Lagerstabile Fibrinogen-Präparate |
| US5899567A (en) * | 1997-09-23 | 1999-05-04 | Morris, Jr.; Joseph E. | Magnetic synchronized stirring and heating test apparatus |
| US6382827B1 (en) * | 2000-11-01 | 2002-05-07 | Dade Behring Inc. | Method and apparatus for mixing liquid solutions using a rotating magnet to generate a stirring vortex action |
| US6467946B1 (en) * | 2001-04-24 | 2002-10-22 | Dade Microscan Inc. | Method and apparatus for mixing liquid samples in a container using rotating magnetic fields |
| JP2005502861A (ja) | 2001-08-10 | 2005-01-27 | サイミックス テクノロジーズ， インコーポレイテッド | 事前処方物を作製および試験するための装置および方法ならびにそのためのシステム |
| EP2130549B1 (en) | 2007-03-22 | 2014-07-16 | The Chemo-Sero-Therapeutic Research Institute | Solid fibrinogen preparation |
| CA3078563A1 (en) | 2011-12-29 | 2013-07-04 | Omrix Biopharmaceuticals Ltd. | Method and device for fast dissolution of solid protein composition |
| TWI590817B (zh) * | 2015-10-14 | 2017-07-11 | 鈺邦科技股份有限公司 | 含浸設備及含浸方法 |
| CN113576756A (zh) * | 2021-07-15 | 2021-11-02 | 伊索曼(中山)医疗器械有限公司 | 提升冻干敷料结构均匀性的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE498056A (enrdf_load_stackoverflow) * | 1949-03-25 | |||
| FR1200467A (fr) * | 1958-06-25 | 1959-12-22 | Rech S Et De Controle Du Caout | Dispositif d'agitation et de régulation thermique, applicable notamment dans les laboratoires |
| GB921719A (en) * | 1960-05-06 | 1963-03-20 | Nat Res Dev | Improvement in magnetic stirrers |
| US3356346A (en) * | 1966-01-03 | 1967-12-05 | Landsberger Kurt | Test tube stirring support |
| CA1072538A (en) * | 1975-07-03 | 1980-02-26 | Leonard E. Brown | Bottom supported magnetic stirring element |
| US3997272A (en) * | 1975-12-15 | 1976-12-14 | Varian Associates | Magnetic stirrer improvement |
| SE397637B (sv) * | 1976-03-09 | 1977-11-14 | Wik G | Magnetomrorare |
-
1980
- 1980-08-25 AT AT0428980A patent/AT371719B/de not_active IP Right Cessation
-
1981
- 1981-07-24 SE SE8104544A patent/SE8104544L/xx unknown
- 1981-07-29 DE DE3129995A patent/DE3129995C2/de not_active Expired
- 1981-08-04 CA CA000383132A patent/CA1182444A/en not_active Expired
- 1981-08-05 NL NLAANVRAGE8103695,A patent/NL189799C/xx not_active IP Right Cessation
- 1981-08-07 DK DK351481A patent/DK157331C/da not_active IP Right Cessation
- 1981-08-12 GB GB8124601A patent/GB2082929B/en not_active Expired
- 1981-08-18 BE BE0/205701A patent/BE890002A/fr not_active IP Right Cessation
- 1981-08-20 FR FR8116002A patent/FR2488802A1/fr active Granted
- 1981-08-20 ES ES504858A patent/ES504858A0/es active Granted
- 1981-08-24 IT IT23609/81A patent/IT1137641B/it active
- 1981-08-24 AR AR286518A patent/AR224086A1/es active
- 1981-08-24 CH CH5442/81A patent/CH659394A5/de not_active IP Right Cessation
- 1981-08-24 JP JP56133224A patent/JPS5789863A/ja active Granted
-
1991
- 1991-11-14 SE SE9103372A patent/SE510742C2/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL8103695A (nl) | 1982-03-16 |
| NL189799B (nl) | 1993-03-01 |
| IT1137641B (it) | 1986-09-10 |
| FR2488802B1 (enrdf_load_stackoverflow) | 1985-01-04 |
| AT371719B (de) | 1983-07-25 |
| NL189799C (nl) | 1993-08-02 |
| IT8123609A0 (it) | 1981-08-24 |
| GB2082929A (en) | 1982-03-17 |
| ATA428980A (de) | 1982-12-15 |
| AR224086A1 (es) | 1981-10-15 |
| DK157331C (da) | 1990-05-14 |
| BE890002A (fr) | 1981-12-16 |
| FR2488802A1 (fr) | 1982-02-26 |
| SE510742C2 (sv) | 1999-06-21 |
| DK351481A (da) | 1982-02-26 |
| DE3129995A1 (de) | 1982-05-27 |
| SE8104544L (sv) | 1982-02-26 |
| ES8303111A1 (es) | 1983-02-01 |
| GB2082929B (en) | 1985-02-27 |
| CA1182444A (en) | 1985-02-12 |
| SE9103372D0 (sv) | 1991-11-14 |
| CH659394A5 (de) | 1987-01-30 |
| JPS5789863A (en) | 1982-06-04 |
| DE3129995C2 (de) | 1987-01-15 |
| ES504858A0 (es) | 1983-02-01 |
| DK157331B (da) | 1989-12-18 |
| SE9103372L (sv) | 1991-11-14 |
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