JPS6219278B2 - - Google Patents
Info
- Publication number
- JPS6219278B2 JPS6219278B2 JP54089407A JP8940779A JPS6219278B2 JP S6219278 B2 JPS6219278 B2 JP S6219278B2 JP 54089407 A JP54089407 A JP 54089407A JP 8940779 A JP8940779 A JP 8940779A JP S6219278 B2 JPS6219278 B2 JP S6219278B2
- Authority
- JP
- Japan
- Prior art keywords
- lubricant
- mortar
- punch
- powder
- tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000314 lubricant Substances 0.000 claims description 34
- 239000004570 mortar (masonry) Substances 0.000 claims description 18
- 239000000843 powder Substances 0.000 claims description 15
- 239000006185 dispersion Substances 0.000 claims description 9
- 239000003826 tablet Substances 0.000 description 26
- 238000000034 method Methods 0.000 description 11
- 238000007906 compression Methods 0.000 description 6
- 238000005507 spraying Methods 0.000 description 6
- 230000006835 compression Effects 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 3
- 239000008116 calcium stearate Substances 0.000 description 3
- 235000013539 calcium stearate Nutrition 0.000 description 3
- 238000000748 compression moulding Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000005461 lubrication Methods 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- MANKSFVECICGLK-UHFFFAOYSA-K aloxiprin Chemical compound [OH-].[Al+3].CC(=O)OC1=CC=CC=C1C([O-])=O.CC(=O)OC1=CC=CC=C1C([O-])=O MANKSFVECICGLK-UHFFFAOYSA-K 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000007891 compressed tablet Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/0005—Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses
- B30B15/0011—Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses lubricating means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/005—Control arrangements
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8940779A JPS5614098A (en) | 1979-07-13 | 1979-07-13 | Externally lubricating tablet making machine |
| US06/165,399 US4373888A (en) | 1979-07-13 | 1980-07-02 | Apparatus for mass-producing medical tablets |
| CH518080A CH639843A5 (fr) | 1979-07-13 | 1980-07-07 | Procede pour la fabrication en serie de comprimes a usage medical et appareil pour sa mise en oeuvre. |
| DE19803026058 DE3026058A1 (de) | 1979-07-13 | 1980-07-09 | Verfahren und vorrichtung zum herstellen medizinischer tabletten |
| IT68105/80A IT1141602B (it) | 1979-07-13 | 1980-07-11 | Dispositivo e procedimento per la produzione in massa di compresse medicinali |
| GB8022804A GB2053787B (en) | 1979-07-13 | 1980-07-11 | Apparatus and method for mass-producing medical tablets |
| FR8015459A FR2460662B1 (fr) | 1979-07-13 | 1980-07-11 | Appareil et procede pour la production en grande serie de comprimes medicaux |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8940779A JPS5614098A (en) | 1979-07-13 | 1979-07-13 | Externally lubricating tablet making machine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5614098A JPS5614098A (en) | 1981-02-10 |
| JPS6219278B2 true JPS6219278B2 (enrdf_load_stackoverflow) | 1987-04-27 |
Family
ID=13969782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8940779A Granted JPS5614098A (en) | 1979-07-13 | 1979-07-13 | Externally lubricating tablet making machine |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4373888A (enrdf_load_stackoverflow) |
| JP (1) | JPS5614098A (enrdf_load_stackoverflow) |
| CH (1) | CH639843A5 (enrdf_load_stackoverflow) |
| DE (1) | DE3026058A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2460662B1 (enrdf_load_stackoverflow) |
| GB (1) | GB2053787B (enrdf_load_stackoverflow) |
| IT (1) | IT1141602B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6410857U (enrdf_load_stackoverflow) * | 1987-07-07 | 1989-01-20 |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3131402A1 (de) * | 1981-08-07 | 1983-02-24 | Kilian & Co GmbH, 5000 Köln | Verfahren und tablettenpresse zum aufeinanderfolgenden herstellen einer vielzahl von tabletten mit gleichem gewicht |
| FR2575406B1 (fr) * | 1984-12-28 | 1987-04-10 | Pont A Mousson | Machine pour la fabrication de bouteilles en matiere plastique avec mise en place de coupelles stabilisatrices et pressurisation interne au moyen d'un gaz |
| DE3520203A1 (de) * | 1985-06-05 | 1986-12-11 | Wilhelm Fette Gmbh, 2053 Schwarzenbek | Rundlaeufer-tablettiermaschine und verfahren zur steuerung ihrer druckrollen |
| GB8530365D0 (en) * | 1985-12-10 | 1986-01-22 | Univ Bath | Manufacture of moulded products |
| DE3930127A1 (de) * | 1989-09-09 | 1991-03-21 | Fette Wilhelm Gmbh | Rundlauf-tablettiermaschine |
| US5158728A (en) * | 1991-04-12 | 1992-10-27 | Elizabeth-Hata International, Inc. | Multi-layer medicinal tablet forming machine and method for using the same |
| JP2681601B2 (ja) * | 1993-11-01 | 1997-11-26 | 協和醗酵工業株式会社 | 外部滑沢式打錠機 |
| DE4412117A1 (de) * | 1994-04-08 | 1995-10-12 | Fette Wilhelm Gmbh | Verfahren und Vorrichtung zum Aufbringen von pulverförmigem Schmier- oder Trennmittel auf die Preßwerkzeuge in Tablettiermaschinen |
| US5838571A (en) * | 1996-01-29 | 1998-11-17 | Alza Corporation | Tablet press monitoring and controlling method and apparatus |
| ATE477793T1 (de) * | 1996-06-14 | 2010-09-15 | Kyowa Hakko Kirin Co Ltd | Eine im mund schnell zerfallende tablette |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| DE19647089A1 (de) * | 1996-11-14 | 1998-05-28 | Bayer Ag | Vorrichtung zum kontrollierten Aufsprühen von pulverförmigen Schmiermitteln auf Stempel und Matrizen von Tablettenpressen |
| JPH11169437A (ja) | 1997-12-03 | 1999-06-29 | Kyowa Hakko Kogyo Co Ltd | 錠剤の製造方法 |
| JP4568426B2 (ja) * | 1998-04-08 | 2010-10-27 | 協和発酵キリン株式会社 | 錠剤の製造方法及び錠剤 |
| WO1999052492A1 (fr) | 1998-04-10 | 1999-10-21 | Kyowa Hakko Kogyo Co., Ltd. | Comprime et procedes de fabrication de comprime |
| CA2587022A1 (en) | 1998-05-18 | 1999-11-25 | Takeda Pharmaceutical Company Limited | Orally disintegrable tablets |
| AU6006899A (en) * | 1998-10-13 | 2000-05-01 | Kyowa Hakko Kogyo Co. Ltd. | Method of applying powder material, tablet production method, powder material application device for upper punch, powder material application device for lower punch, powder material application device, and external lubrication compressing machine |
| US6482349B1 (en) | 1998-11-02 | 2002-11-19 | Sumitomo Special Metals Co., Ltd. | Powder pressing apparatus and powder pressing method |
| JP3737331B2 (ja) * | 1999-03-31 | 2006-01-18 | Ｓｐｓシンテックス株式会社 | 粉体の自動充填方法及び装置 |
| CA2367406A1 (en) * | 1999-04-19 | 2000-10-26 | Shuji Morimoto | Rotary type powder compression molding machine |
| GB2361453B (en) * | 2000-01-27 | 2003-10-15 | Victor Ken Seng Wu | Lubrication device adapted to be used in a punching machine |
| DE60142853D1 (enrdf_load_stackoverflow) | 2000-12-08 | 2010-09-30 | Kyowa Hakko Kirin Co Ltd | |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| JP4108605B2 (ja) * | 2001-11-13 | 2008-06-25 | 協和醗酵工業株式会社 | アミノ酸含有口腔内速崩壊錠及びその製造方法 |
| US20040056375A1 (en) * | 2002-07-19 | 2004-03-25 | Gary Bubb | Method and apparatus for making miniature tablets |
| US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| EP1944007A3 (en) * | 2004-09-24 | 2008-07-23 | BioProgress Technology Limited | Additional improvements in powder compaction and enrobing |
| EP1807040A1 (en) * | 2004-09-24 | 2007-07-18 | BioProgress Technology Limited | Additional improvements in powder compaction and enrobing |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| ES2409347T3 (es) | 2004-10-21 | 2013-06-26 | Aptalis Pharmatech, Inc. | Composiciones farmacéuticas de sabor enmascarado con agentes porogénicos gastrosolubles |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| CN103585127A (zh) * | 2008-02-28 | 2014-02-19 | Abbvie公司 | 片剂和其制备方法 |
| CN102958515A (zh) | 2009-12-02 | 2013-03-06 | 阿普塔利斯制药有限公司 | 非索非那定微胶囊及含有非索非那定微胶囊的组合物 |
| CN102582111A (zh) * | 2012-01-18 | 2012-07-18 | 金坛市威克压片机械制造有限公司 | 一种压片机装料深度微调装置 |
| DE102016123279B4 (de) * | 2016-12-01 | 2019-02-21 | Fette Compacting Gmbh | Verfahren und System zum Zuführen eines Schmier- oder Trennmittels zu Presswerkzeugen einer Tablettenpresse |
| JP2019111565A (ja) * | 2017-12-25 | 2019-07-11 | 株式会社菊水製作所 | 制御装置、制御方法 |
| EP3662898A1 (en) * | 2018-12-07 | 2020-06-10 | Tillotts Pharma AG | Solid composition comprising mesalazine |
| USD947406S1 (en) | 2020-03-18 | 2022-03-29 | Laura Patricia Matamoros Vargas | Mold for vaginal ovules |
| USD959696S1 (en) | 2020-03-18 | 2022-08-02 | Laura Patricia Matamoros Vargas | Mold for vaginal ovules |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE265970C (enrdf_load_stackoverflow) * | ||||
| US3158111A (en) * | 1962-06-06 | 1964-11-24 | Smith Kline French Lab | Method and apparatus for forming tablets |
| US3255716A (en) * | 1962-12-10 | 1966-06-14 | Upjohn Co | Measurement of forces within a tableting machine |
| US3332367A (en) * | 1965-07-15 | 1967-07-25 | Upjohn Co | Apparatus for making tablets |
| GB1335153A (en) * | 1971-09-02 | 1973-10-24 | Purex Corp | Method of tabletting halocyanuric acid |
| DE2520662C3 (de) * | 1975-05-09 | 1983-11-03 | Wilhelm Fette Gmbh, 2053 Schwarzenbek | Einrichtung zum Überwachen der Preßkräfte der Stempel einer Tablettenpresse |
| US4047866A (en) * | 1976-11-22 | 1977-09-13 | The Dow Chemical Company | Automatic self-lubricating rotary tablet press |
| DD136026A5 (de) * | 1977-04-20 | 1979-06-13 | Thomae Gmbh Dr K | Verfahren zum bespruehen der verdichtungswerkzeuge mit schmiermitteln |
| DE2742572B1 (de) * | 1977-09-22 | 1979-03-29 | Fette Wilhelm Gmbh | Verfahren zum Herstellen von Tabletten und Tablettenpresse |
-
1979
- 1979-07-13 JP JP8940779A patent/JPS5614098A/ja active Granted
-
1980
- 1980-07-02 US US06/165,399 patent/US4373888A/en not_active Expired - Lifetime
- 1980-07-07 CH CH518080A patent/CH639843A5/fr not_active IP Right Cessation
- 1980-07-09 DE DE19803026058 patent/DE3026058A1/de active Granted
- 1980-07-11 IT IT68105/80A patent/IT1141602B/it active
- 1980-07-11 GB GB8022804A patent/GB2053787B/en not_active Expired
- 1980-07-11 FR FR8015459A patent/FR2460662B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6410857U (enrdf_load_stackoverflow) * | 1987-07-07 | 1989-01-20 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2053787B (en) | 1983-10-19 |
| IT8068105A0 (it) | 1980-07-11 |
| FR2460662A1 (fr) | 1981-01-30 |
| IT1141602B (it) | 1986-10-01 |
| US4373888A (en) | 1983-02-15 |
| DE3026058A1 (de) | 1981-06-04 |
| FR2460662B1 (fr) | 1985-10-04 |
| CH639843A5 (fr) | 1983-12-15 |
| JPS5614098A (en) | 1981-02-10 |
| GB2053787A (en) | 1981-02-11 |
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