JPS6125356B2 - - Google Patents

Info

Publication number
JPS6125356B2
JPS6125356B2 JP54011560A JP1156079A JPS6125356B2 JP S6125356 B2 JPS6125356 B2 JP S6125356B2 JP 54011560 A JP54011560 A JP 54011560A JP 1156079 A JP1156079 A JP 1156079A JP S6125356 B2 JPS6125356 B2 JP S6125356B2
Authority
JP
Japan
Prior art keywords
water
antibiotic
soluble
culture
methanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54011560A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55104296A (en
Inventor
Satoru Imada
Setsuo Harada
Mitsuko Asai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP1156079A priority Critical patent/JPS55104296A/ja
Priority to AU54518/80A priority patent/AU534530B2/en
Priority to DK12580A priority patent/DK12580A/da
Priority to GR60953A priority patent/GR73818B/el
Priority to US06/113,132 priority patent/US4518529A/en
Priority to PT70710A priority patent/PT70710A/pt
Priority to CH67680A priority patent/CH646432A5/de
Priority to HU80180A priority patent/HU181721B/hu
Priority to ZA00800496A priority patent/ZA80496B/xx
Priority to NL8000628A priority patent/NL8000628A/nl
Priority to FR8002162A priority patent/FR2447922A1/fr
Priority to ES488836A priority patent/ES488836A0/es
Priority to SU802878699A priority patent/SU1075984A3/ru
Priority to GB8003402A priority patent/GB2042532B/en
Priority to BE0/199232A priority patent/BE881509A/fr
Priority to PH23567A priority patent/PH14316A/en
Priority to IT19645/80A priority patent/IT1130246B/it
Priority to DE19803003624 priority patent/DE3003624A1/de
Priority to SE8000842A priority patent/SE8000842L/xx
Publication of JPS55104296A publication Critical patent/JPS55104296A/ja
Publication of JPS6125356B2 publication Critical patent/JPS6125356B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP1156079A 1979-02-02 1979-02-02 Antibiotic substance c-19393s2 and its preparation Granted JPS55104296A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
JP1156079A JPS55104296A (en) 1979-02-02 1979-02-02 Antibiotic substance c-19393s2 and its preparation
AU54518/80A AU534530B2 (en) 1979-02-02 1980-01-10 5-aza-(3.2.0)-heptane derivatives
DK12580A DK12580A (da) 1979-02-02 1980-01-11 Antibiotika c-19393s2 og h2
GR60953A GR73818B (enExample) 1979-02-02 1980-01-14
US06/113,132 US4518529A (en) 1979-02-02 1980-01-17 Antibiotics C-19393S2
PT70710A PT70710A (en) 1979-02-02 1980-01-18 Antibiotics c-19393 s2 and h2
CH67680A CH646432A5 (de) 1979-02-02 1980-01-28 Beta-lactam-antibiotika.
HU80180A HU181721B (en) 1979-02-02 1980-01-28 Process for preparing antibiotics c-19393sdown 2 and c-1939hdown 2
ZA00800496A ZA80496B (en) 1979-02-02 1980-01-28 Antibiotics c-19393s2 and h2
NL8000628A NL8000628A (nl) 1979-02-02 1980-01-31 Antibiotica c-19393s2 en h2.
FR8002162A FR2447922A1 (fr) 1979-02-02 1980-01-31 Antibiotiques c-19393 s2 et c-19393 h2 et leurs sels, leur procede de preparation a partir de micro-organismes du genre streptomyces et leur utilisation dans des preparations medicinales
ES488836A ES488836A0 (es) 1979-02-02 1980-01-31 Metodo de producir antibioticos del tipo basado en streptomyces.
SU802878699A SU1075984A3 (ru) 1979-02-02 1980-02-01 Способ получени антибиотика @ -19393 @ и/или @ -19393 @
GB8003402A GB2042532B (en) 1979-02-02 1980-02-01 Antibiotics c-19393 s2 and 'i
BE0/199232A BE881509A (fr) 1979-02-02 1980-02-01 Antibiotiques c-19393 s2 et c-19393 h2 et leurs sels, leur procede de preparation a partir de micro-organismes et leur utilisation
PH23567A PH14316A (en) 1979-02-02 1980-02-01 Antibiotics c-19393 s2 and h2 and method of preparation thereof
IT19645/80A IT1130246B (it) 1979-02-02 1980-02-01 Antibiotico e procedimento microbiologico per produrlo
DE19803003624 DE3003624A1 (de) 1979-02-02 1980-02-01 Antibiotica c-19393 s tief 2 und h tief 2
SE8000842A SE8000842L (sv) 1979-02-02 1980-02-01 Nya antibiotika

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1156079A JPS55104296A (en) 1979-02-02 1979-02-02 Antibiotic substance c-19393s2 and its preparation

Publications (2)

Publication Number Publication Date
JPS55104296A JPS55104296A (en) 1980-08-09
JPS6125356B2 true JPS6125356B2 (enExample) 1986-06-14

Family

ID=11781312

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1156079A Granted JPS55104296A (en) 1979-02-02 1979-02-02 Antibiotic substance c-19393s2 and its preparation

Country Status (3)

Country Link
JP (1) JPS55104296A (enExample)
BE (1) BE881509A (enExample)
ZA (1) ZA80496B (enExample)

Also Published As

Publication number Publication date
JPS55104296A (en) 1980-08-09
BE881509A (fr) 1980-08-01
ZA80496B (en) 1981-02-25

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