JPS61227520A - マイクロスフエア - Google Patents
マイクロスフエアInfo
- Publication number
- JPS61227520A JPS61227520A JP60068410A JP6841085A JPS61227520A JP S61227520 A JPS61227520 A JP S61227520A JP 60068410 A JP60068410 A JP 60068410A JP 6841085 A JP6841085 A JP 6841085A JP S61227520 A JPS61227520 A JP S61227520A
- Authority
- JP
- Japan
- Prior art keywords
- porous
- powder
- substance
- microspheres
- fine powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000004005 microsphere Substances 0.000 title claims abstract description 30
- 239000000843 powder Substances 0.000 claims abstract description 54
- 239000000126 substance Substances 0.000 claims abstract description 34
- 238000000576 coating method Methods 0.000 claims abstract description 9
- 239000011248 coating agent Substances 0.000 claims abstract description 8
- 239000011148 porous material Substances 0.000 claims description 19
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract description 18
- 239000002245 particle Substances 0.000 abstract description 13
- 239000002904 solvent Substances 0.000 abstract description 10
- 239000001913 cellulose Substances 0.000 abstract description 8
- 229920002678 cellulose Polymers 0.000 abstract description 8
- 239000003814 drug Substances 0.000 abstract description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract description 6
- 229940079593 drug Drugs 0.000 abstract description 6
- 239000004677 Nylon Substances 0.000 abstract description 5
- 238000002156 mixing Methods 0.000 abstract description 5
- 229920001778 nylon Polymers 0.000 abstract description 5
- 239000004698 Polyethylene Substances 0.000 abstract description 4
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract description 4
- 239000003905 agrochemical Substances 0.000 abstract description 3
- 239000003337 fertilizer Substances 0.000 abstract description 3
- 235000013305 food Nutrition 0.000 abstract description 3
- -1 polyethylene Polymers 0.000 abstract description 3
- 229920000573 polyethylene Polymers 0.000 abstract description 3
- 239000000377 silicon dioxide Substances 0.000 abstract description 3
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract description 2
- 235000012216 bentonite Nutrition 0.000 abstract description 2
- 238000004090 dissolution Methods 0.000 abstract description 2
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 abstract description 2
- 239000011347 resin Substances 0.000 abstract description 2
- 229920005989 resin Polymers 0.000 abstract description 2
- 238000007864 suspending Methods 0.000 abstract description 2
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 abstract description 2
- 230000001276 controlling effect Effects 0.000 abstract 1
- 238000004945 emulsification Methods 0.000 abstract 1
- 238000012856 packing Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 16
- 239000007788 liquid Substances 0.000 description 10
- 239000010419 fine particle Substances 0.000 description 8
- 229960001047 methyl salicylate Drugs 0.000 description 8
- 239000004408 titanium dioxide Substances 0.000 description 8
- 238000010828 elution Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 5
- 239000004926 polymethyl methacrylate Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 239000004570 mortar (masonry) Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 238000007922 dissolution test Methods 0.000 description 2
- 239000003822 epoxy resin Substances 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 229920000647 polyepoxide Polymers 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000013268 sustained release Methods 0.000 description 2
- 239000012730 sustained-release form Substances 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 229920013716 polyethylene resin Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- CMDGQTVYVAKDNA-UHFFFAOYSA-N propane-1,2,3-triol;hydrate Chemical compound O.OCC(O)CO CMDGQTVYVAKDNA-UHFFFAOYSA-N 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fertilizers (AREA)
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60068410A JPS61227520A (ja) | 1985-04-02 | 1985-04-02 | マイクロスフエア |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60068410A JPS61227520A (ja) | 1985-04-02 | 1985-04-02 | マイクロスフエア |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61227520A true JPS61227520A (ja) | 1986-10-09 |
| JPH0530499B2 JPH0530499B2 (enrdf_load_stackoverflow) | 1993-05-10 |
Family
ID=13372874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60068410A Granted JPS61227520A (ja) | 1985-04-02 | 1985-04-02 | マイクロスフエア |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61227520A (enrdf_load_stackoverflow) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01106817A (ja) * | 1987-10-21 | 1989-04-24 | Kiteii:Kk | 多孔質内封入体及びその製造方法 |
| JPH01316302A (ja) * | 1988-03-03 | 1989-12-21 | Hokko Chem Ind Co Ltd | 農薬の徐放性付与剤、徐放性農薬およびその製法 |
| JPH04210239A (ja) * | 1990-12-13 | 1992-07-31 | Osaka Gas Co Ltd | 吸着剤およびその製造方法 |
| JPH05309260A (ja) * | 1991-04-22 | 1993-11-22 | L'oreal Sa | 被覆多孔質微小球及びこれを含有する化粧料組成物 |
| WO2004096281A1 (ja) * | 2003-04-29 | 2004-11-11 | Kowa Co., Ltd. | 溶出性に優れた超難水溶性薬物含有組成物及びその製造法 |
| WO2004096280A1 (ja) * | 2003-04-29 | 2004-11-11 | Kowa Co., Ltd. | 超難水溶性薬物含有組成物及びその製造法 |
| EP1964875A4 (en) * | 2005-12-14 | 2009-11-11 | Ube Industries | POWDER OF POROUS POLYAMIDE PARTICULARLY LOADED WITH INORGANIC COMPOUND |
| WO2010108211A1 (en) * | 2009-03-27 | 2010-09-30 | Australian Nuclear Science And Technology Organisation | Triggered release |
| WO2015078318A1 (zh) * | 2013-11-29 | 2015-06-04 | 海尔集团公司 | 抗菌保鲜组件及其制备方法，以及冰箱 |
| JP2015110637A (ja) * | 2008-09-04 | 2015-06-18 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 非水性担体を用いた徐放性製剤 |
| CN105565969A (zh) * | 2015-12-10 | 2016-05-11 | 深圳市芭田生态工程股份有限公司 | 双包膜缓释微球钙肥及其制备方法和应用 |
| JP2016155866A (ja) * | 2010-04-28 | 2016-09-01 | シンジェンタ パーティシペーションズ アーゲー | 安定化された農薬組成物 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6394063B2 (ja) | 2014-05-22 | 2018-09-26 | 株式会社村田製作所 | 組電池、蓄電装置、蓄電システム、電子機器、電動車両および電力システム |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5630055A (en) * | 1979-08-21 | 1981-03-26 | Daiwa Seisakusho:Kk | Preparation of mold of pasted shell |
| JPS57136513A (en) * | 1981-02-18 | 1982-08-23 | Nitto Electric Ind Co Ltd | Material for controlling release of physiologically active substance |
-
1985
- 1985-04-02 JP JP60068410A patent/JPS61227520A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5630055A (en) * | 1979-08-21 | 1981-03-26 | Daiwa Seisakusho:Kk | Preparation of mold of pasted shell |
| JPS57136513A (en) * | 1981-02-18 | 1982-08-23 | Nitto Electric Ind Co Ltd | Material for controlling release of physiologically active substance |
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01106817A (ja) * | 1987-10-21 | 1989-04-24 | Kiteii:Kk | 多孔質内封入体及びその製造方法 |
| JPH01316302A (ja) * | 1988-03-03 | 1989-12-21 | Hokko Chem Ind Co Ltd | 農薬の徐放性付与剤、徐放性農薬およびその製法 |
| JPH04210239A (ja) * | 1990-12-13 | 1992-07-31 | Osaka Gas Co Ltd | 吸着剤およびその製造方法 |
| JPH05309260A (ja) * | 1991-04-22 | 1993-11-22 | L'oreal Sa | 被覆多孔質微小球及びこれを含有する化粧料組成物 |
| US8101207B2 (en) * | 2003-04-29 | 2012-01-24 | Kowa Co., Ltd. | Composition containing medicine extremely slightly soluble in water and method for preparation thereof |
| WO2004096281A1 (ja) * | 2003-04-29 | 2004-11-11 | Kowa Co., Ltd. | 溶出性に優れた超難水溶性薬物含有組成物及びその製造法 |
| WO2004096280A1 (ja) * | 2003-04-29 | 2004-11-11 | Kowa Co., Ltd. | 超難水溶性薬物含有組成物及びその製造法 |
| JPWO2004096281A1 (ja) * | 2003-04-29 | 2006-07-13 | 興和株式会社 | 溶出性に優れた超難水溶性薬物含有組成物及びその製造法 |
| US8105630B2 (en) | 2003-04-29 | 2012-01-31 | Kowa Co., Ltd. | Composition containing medicine extremely slightly soluble in water being excellent in eluting property and method for preparation thereof |
| JP4579825B2 (ja) * | 2003-04-29 | 2010-11-10 | 興和株式会社 | 溶出性に優れた超難水溶性薬物含有組成物及びその製造法 |
| JP5262112B2 (ja) * | 2005-12-14 | 2013-08-14 | 宇部興産株式会社 | 無機化合物担持ポリアミド多孔質粒子からなる粉末が分散されている化粧品組成物 |
| EP1964875A4 (en) * | 2005-12-14 | 2009-11-11 | Ube Industries | POWDER OF POROUS POLYAMIDE PARTICULARLY LOADED WITH INORGANIC COMPOUND |
| JP2015110637A (ja) * | 2008-09-04 | 2015-06-18 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 非水性担体を用いた徐放性製剤 |
| WO2010108211A1 (en) * | 2009-03-27 | 2010-09-30 | Australian Nuclear Science And Technology Organisation | Triggered release |
| AU2009342893B2 (en) * | 2009-03-27 | 2014-03-06 | Australian Nuclear Science And Technology Organisation | Triggered release |
| US9222060B2 (en) | 2009-03-27 | 2015-12-29 | Australian Nuclear Science And Technology Organisation | Triggered release |
| JP2016155866A (ja) * | 2010-04-28 | 2016-09-01 | シンジェンタ パーティシペーションズ アーゲー | 安定化された農薬組成物 |
| WO2015078318A1 (zh) * | 2013-11-29 | 2015-06-04 | 海尔集团公司 | 抗菌保鲜组件及其制备方法，以及冰箱 |
| CN105565969A (zh) * | 2015-12-10 | 2016-05-11 | 深圳市芭田生态工程股份有限公司 | 双包膜缓释微球钙肥及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0530499B2 (enrdf_load_stackoverflow) | 1993-05-10 |
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