JPS61146191A - (S)−γ−ハロ−β−ヒドロキシ酪酸エステルの製造法 - Google Patents
(S)−γ−ハロ−β−ヒドロキシ酪酸エステルの製造法Info
- Publication number
- JPS61146191A JPS61146191A JP27027284A JP27027284A JPS61146191A JP S61146191 A JPS61146191 A JP S61146191A JP 27027284 A JP27027284 A JP 27027284A JP 27027284 A JP27027284 A JP 27027284A JP S61146191 A JPS61146191 A JP S61146191A
- Authority
- JP
- Japan
- Prior art keywords
- halo
- genus
- acid ester
- group
- asymmetric reduction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27027284A JPS61146191A (ja) | 1984-12-20 | 1984-12-20 | (S)−γ−ハロ−β−ヒドロキシ酪酸エステルの製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27027284A JPS61146191A (ja) | 1984-12-20 | 1984-12-20 | (S)−γ−ハロ−β−ヒドロキシ酪酸エステルの製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61146191A true JPS61146191A (ja) | 1986-07-03 |
| JPH047195B2 JPH047195B2 (enExample) | 1992-02-10 |
Family
ID=17483936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP27027284A Granted JPS61146191A (ja) | 1984-12-20 | 1984-12-20 | (S)−γ−ハロ−β−ヒドロキシ酪酸エステルの製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61146191A (enExample) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06153969A (ja) * | 1991-11-07 | 1994-06-03 | Asahi Breweries Ltd | ω−ケト脂肪酸エステル還元法 |
| US5413921A (en) * | 1992-05-28 | 1995-05-09 | Ajinomoto Co., Ltd. | Method of the production of (s)-gamma-halogenated-γ-hydroxybutyric acid esters |
| US5430171A (en) * | 1992-06-02 | 1995-07-04 | Takasago International Corporation | T-butyl (R)-(-)-4-cyano-3-hydroxybutyrate and process for preparing the same |
| EP0606899A3 (en) * | 1993-01-12 | 1995-07-05 | Daicel Chem | Processes for the preparation of optically active 4-halo-3-hydroxy butyric acid esters. |
| WO1998035025A1 (en) * | 1997-02-07 | 1998-08-13 | Kaneka Corporation | Novel carbonyl reductase, gene that encodes the same, and method of utilizing these |
| US6001618A (en) * | 1997-12-25 | 1999-12-14 | Daicel Chemical Industries, Ltd. | Haloacetoacetate reductase, method for producing said enzyme, and method for producing alcohols using said enzyme |
| US6168935B1 (en) | 1998-02-25 | 2001-01-02 | Daicel Chemical Industries, Ltd. | Preparation of optically active alcohol substituted with one or more halogen atoms |
| EP1408107A2 (en) | 2002-10-07 | 2004-04-14 | Daiso Co., Ltd. | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene |
| KR100461561B1 (ko) * | 1998-07-24 | 2005-04-06 | 삼성정밀화학 주식회사 | (s)-3-카르복시-4-브로모부티르산의 제조방법 |
| US7879585B2 (en) | 2006-10-02 | 2011-02-01 | Codexis, Inc. | Ketoreductase enzymes and uses thereof |
-
1984
- 1984-12-20 JP JP27027284A patent/JPS61146191A/ja active Granted
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06153969A (ja) * | 1991-11-07 | 1994-06-03 | Asahi Breweries Ltd | ω−ケト脂肪酸エステル還元法 |
| US5413921A (en) * | 1992-05-28 | 1995-05-09 | Ajinomoto Co., Ltd. | Method of the production of (s)-gamma-halogenated-γ-hydroxybutyric acid esters |
| US5430171A (en) * | 1992-06-02 | 1995-07-04 | Takasago International Corporation | T-butyl (R)-(-)-4-cyano-3-hydroxybutyrate and process for preparing the same |
| EP0606899A3 (en) * | 1993-01-12 | 1995-07-05 | Daicel Chem | Processes for the preparation of optically active 4-halo-3-hydroxy butyric acid esters. |
| US5559030A (en) * | 1993-01-12 | 1996-09-24 | Daicel Chemical Industries, Ltd. | Processes for production of optically active 4-halo-3-hydroxybutyric acid esters |
| US6218156B1 (en) | 1997-02-07 | 2001-04-17 | Kaneka Corporation | Gene encoding carbonyl reductase, and methods for its use |
| WO1998035025A1 (en) * | 1997-02-07 | 1998-08-13 | Kaneka Corporation | Novel carbonyl reductase, gene that encodes the same, and method of utilizing these |
| US6448052B2 (en) | 1997-02-07 | 2002-09-10 | Kaneka Corporation | Carbonyl reductase enzyme and methods for its use |
| US6001618A (en) * | 1997-12-25 | 1999-12-14 | Daicel Chemical Industries, Ltd. | Haloacetoacetate reductase, method for producing said enzyme, and method for producing alcohols using said enzyme |
| US6218157B1 (en) | 1997-12-25 | 2001-04-17 | Daicel Chemical Industries, Ltd. | Haloacetoacetate reductase, method for producing said enzyme, and method for producing alcohols using said enzyme |
| US6168935B1 (en) | 1998-02-25 | 2001-01-02 | Daicel Chemical Industries, Ltd. | Preparation of optically active alcohol substituted with one or more halogen atoms |
| KR100461561B1 (ko) * | 1998-07-24 | 2005-04-06 | 삼성정밀화학 주식회사 | (s)-3-카르복시-4-브로모부티르산의 제조방법 |
| EP1408107A2 (en) | 2002-10-07 | 2004-04-14 | Daiso Co., Ltd. | Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene |
| US7879585B2 (en) | 2006-10-02 | 2011-02-01 | Codexis, Inc. | Ketoreductase enzymes and uses thereof |
| US8273547B2 (en) | 2006-10-02 | 2012-09-25 | Codexis, Inc. | Engineered ketoreductases and methods for producing stereoisomerically pure statins |
| US8617864B2 (en) | 2006-10-02 | 2013-12-31 | Codexis, Inc. | Polynucleotides encoding ketoreductases for producing stereoisomerically pure statins and synthetic intermediates therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH047195B2 (enExample) | 1992-02-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS61146191A (ja) | (S)−γ−ハロ−β−ヒドロキシ酪酸エステルの製造法 | |
| JPS63284184A (ja) | 光学活性化合物およびその製造方法 | |
| US5773240A (en) | Optically active α-substituted carboxylic acid derivatives and method for producing the same | |
| JPH01132399A (ja) | 光学活性な不飽和アルコール及びそのエステル体の製造法 | |
| JPH01281098A (ja) | 光学活性カルボン酸及び光学活性カルボン酸エステルの製造方法 | |
| JPH02104295A (ja) | 光学活性アミン及びその誘導体の製造方法 | |
| JP3217301B2 (ja) | 光学活性グリシド酸エステル及び光学活性グリセリン酸エステルの製造方法 | |
| JPS63245694A (ja) | 光学活性含硫カルボン酸およびその対掌体エステルの製法 | |
| JPS63202398A (ja) | 光学活性シアノヒドリン誘導体の製造方法 | |
| JPH0614876B2 (ja) | 光学活性α−ヒドロキシケトンおよびそのカルボン酸エステルの製造法 | |
| US5177007A (en) | Process for producing optically active r-(+)-2,3-dichloro-1-propanol using microorganism | |
| JPS63293A (ja) | 光学活性な4−ヒドロキシ−2−シクロペンテノンの製造方法 | |
| JP3747640B2 (ja) | 光学活性1,2−ジオール環状炭酸エステルの製造法 | |
| JP2981250B2 (ja) | D―パントテノニトリルの製造法 | |
| JP3893721B2 (ja) | 光学活性化合物の製造方法 | |
| JP2828729B2 (ja) | 光学活性1,3―ブタンジオールの製造法 | |
| JPS5953838B2 (ja) | β−ヒドロキシ吉草酸の製造方法 | |
| JPS6225997A (ja) | 光学活性シアノヒドリン誘導体の製造方法 | |
| JPS58126792A (ja) | 微生物による光学活性物質の製法 | |
| JPS6363387A (ja) | (R)―γ―ブチロラクトン―γ―プロピオン酸エステルの製造方法 | |
| JPH06277078A (ja) | パラヒドロキシベンズアルデヒドの製造方法 | |
| JPH0593A (ja) | 光学活性3−メチルアジピン酸の製造方法 | |
| JPH02203796A (ja) | 酵素または微生物による光学分割方法 | |
| JPS60153797A (ja) | メバロン酸の発酵生産法 | |
| JPS63109797A (ja) | 光学活性なシクロペンテノン類の製法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |