JPS61119189A - プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法 - Google Patents

プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法

Info

Publication number
JPS61119189A
JPS61119189A JP59241457A JP24145784A JPS61119189A JP S61119189 A JPS61119189 A JP S61119189A JP 59241457 A JP59241457 A JP 59241457A JP 24145784 A JP24145784 A JP 24145784A JP S61119189 A JPS61119189 A JP S61119189A
Authority
JP
Japan
Prior art keywords
precursor
cells
plasminogen activator
medium
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59241457A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0558709B2 (cg-RX-API-DMAC7.html
Inventor
Kazumi Mizumoto
水本 一美
Takahiro Kawakami
川上 隆弘
Hirobumi Arimura
有村 博文
Tatsukage Mori
森 樹蔭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Priority to JP59241457A priority Critical patent/JPS61119189A/ja
Publication of JPS61119189A publication Critical patent/JPS61119189A/ja
Publication of JPH0558709B2 publication Critical patent/JPH0558709B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP59241457A 1984-11-15 1984-11-15 プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法 Granted JPS61119189A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP59241457A JPS61119189A (ja) 1984-11-15 1984-11-15 プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59241457A JPS61119189A (ja) 1984-11-15 1984-11-15 プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法

Publications (2)

Publication Number Publication Date
JPS61119189A true JPS61119189A (ja) 1986-06-06
JPH0558709B2 JPH0558709B2 (cg-RX-API-DMAC7.html) 1993-08-27

Family

ID=17074595

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59241457A Granted JPS61119189A (ja) 1984-11-15 1984-11-15 プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法

Country Status (1)

Country Link
JP (1) JPS61119189A (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6384490A (ja) * 1986-09-29 1988-04-15 Green Cross Corp:The プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法
WO2001085945A1 (fr) * 2000-05-10 2001-11-15 Suntory Limited Procede permettant d'inhiber la formation de produits secondaires dans la production d'un polypeptide genetiquement modifie

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOCHIMICA ET BIOPHYSICA ACTA=1977 *
J.AM.MED.ASSOC=1976 *
JOURNAL OF BIOLOGICAL CHEMISTRY=1982 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6384490A (ja) * 1986-09-29 1988-04-15 Green Cross Corp:The プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法
WO2001085945A1 (fr) * 2000-05-10 2001-11-15 Suntory Limited Procede permettant d'inhiber la formation de produits secondaires dans la production d'un polypeptide genetiquement modifie
US7547529B1 (en) 2000-05-10 2009-06-16 Asubio Pharma Co., Ltd. Methods for reducing the formation of by-products in the production of recombinant polypeptides

Also Published As

Publication number Publication date
JPH0558709B2 (cg-RX-API-DMAC7.html) 1993-08-27

Similar Documents

Publication Publication Date Title
FI81377B (fi) Foerfarande foer framstaellning av maenniskocellinje och dess anvaendning vid produktion av tpa och pro-tpa.
JPH0638743A (ja) 抗プロテインcモノクローナル抗体およびそれを産生するハイブリドーマ
CA2452767C (en) Genetic recombinant ecarin and process for preparing the same
JP2824430B2 (ja) 血液凝固第▲vii▼因子または活性型血液凝固第▲vii▼因子の調製方法
JPS61119189A (ja) プラスミノ−ゲンアクチベ−タ−前駆体の産生増強方法
EP0139447B1 (en) A process for preparing urokinase zymogen
EP0342931B1 (en) Method for the production of human tissue type plasminogen activator
Misaki et al. Studies on the Protease Constitution of Aspergillus oryzae Part I. Systematic Separation and Purification of Proteases
EP0151996B1 (en) Process for the preparation of a double-chain plasminogen activator
EP0363712A2 (en) Hybrid monoclonal antibodies, their production and use
JPH02142494A (ja) 抗ウロキナーゼモノクローナル抗体
JPS6119486A (ja) 組織プラスミノ−ゲンアクチベ−タ−、その製法及びその利用
JPH0736755B2 (ja) プラスミノーゲン・アクチベーター前駆体含有組成物
EP0196226A2 (en) Method for preparing a monoclonal antibody against plasminogen-activating factor
US5139939A (en) Process for the production of human tissue plasminogen activator and cell strain useful therefor
KR980009454A (ko) 바실러스속 균주 유래의 혈전용해효소
JPS61246131A (ja) 新しいタイプのプラスミノ−ゲン活性化因子及びその調製方法
JPH05260969A (ja) モノクローナル抗体によるプラスミノーゲン活性化因子の精製法
JPH01256385A (ja) 組織型プラスミノーゲン活性化因子の製造法
JPH03277294A (ja) 組換え型ヒトアンジオテンシノーゲンの製造方法
CA2095577A1 (en) Purification of plasminogen activator inhibitor 2 by immunoaffinity chromatography
FENTON II PART L STRUCTURE OF THROMBIN AND THROMBiN DERIVATIVES
JPH04218368A (ja) プラスミノーゲン・アクチベーター前駆体の製造法
JPH05310795A (ja) ヒト細胞性フィブロネクチン、 その製造法及び細胞株
JPS6379593A (ja) tPAを精製する方法

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term