JPS60253455A - 骨形成因子を含有する生体材料とその製造方法 - Google Patents

骨形成因子を含有する生体材料とその製造方法

Info

Publication number
JPS60253455A
JPS60253455A JP59109020A JP10902084A JPS60253455A JP S60253455 A JPS60253455 A JP S60253455A JP 59109020 A JP59109020 A JP 59109020A JP 10902084 A JP10902084 A JP 10902084A JP S60253455 A JPS60253455 A JP S60253455A
Authority
JP
Japan
Prior art keywords
bone
collagen
biomaterial
living body
material containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59109020A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0575425B2 (de
Inventor
邦夫 高岡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyocera Corp
Nitta Gelatin Inc
Original Assignee
Kyocera Corp
Nitta Gelatin Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyocera Corp, Nitta Gelatin Inc filed Critical Kyocera Corp
Priority to JP59109020A priority Critical patent/JPS60253455A/ja
Priority to GB08513390A priority patent/GB2164042B/en
Priority to DE19853519073 priority patent/DE3519073A1/de
Priority to CH2249/85A priority patent/CH667394A5/de
Priority to FR858507991A priority patent/FR2564732B1/fr
Publication of JPS60253455A publication Critical patent/JPS60253455A/ja
Publication of JPH0575425B2 publication Critical patent/JPH0575425B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
JP59109020A 1984-05-28 1984-05-28 骨形成因子を含有する生体材料とその製造方法 Granted JPS60253455A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP59109020A JPS60253455A (ja) 1984-05-28 1984-05-28 骨形成因子を含有する生体材料とその製造方法
GB08513390A GB2164042B (en) 1984-05-28 1985-05-28 Artificial bone forming composition
DE19853519073 DE3519073A1 (de) 1984-05-28 1985-05-28 Kuenstliches knochenerzeugendes biomaterial und verfahren zu seiner herstellung
CH2249/85A CH667394A5 (de) 1984-05-28 1985-05-28 Kuenstliches knochenbildendes biomaterial und dieses enthaltendes implantationsmaterial.
FR858507991A FR2564732B1 (fr) 1984-05-28 1985-05-28 Biomatiere osteoformatrice artificielle et son procede de fabrication

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59109020A JPS60253455A (ja) 1984-05-28 1984-05-28 骨形成因子を含有する生体材料とその製造方法

Publications (2)

Publication Number Publication Date
JPS60253455A true JPS60253455A (ja) 1985-12-14
JPH0575425B2 JPH0575425B2 (de) 1993-10-20

Family

ID=14499552

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59109020A Granted JPS60253455A (ja) 1984-05-28 1984-05-28 骨形成因子を含有する生体材料とその製造方法

Country Status (5)

Country Link
JP (1) JPS60253455A (de)
CH (1) CH667394A5 (de)
DE (1) DE3519073A1 (de)
FR (1) FR2564732B1 (de)
GB (1) GB2164042B (de)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6216421A (ja) * 1984-10-24 1987-01-24 コラ−ゲン・コ−ポレイシヨン 誘導性コラ−ゲン・ベ−ス骨修復調製物
JPS62135431A (ja) * 1985-12-07 1987-06-18 Katsuyuki Fujii 液状骨形成剤からなる注射液
JPS6365872A (ja) * 1986-09-08 1988-03-24 新田ゼラチン株式会社 骨形成用注入材料
JPS63105765A (ja) * 1986-10-24 1988-05-11 株式会社 アドバンス インプラント
JPS63238867A (ja) * 1987-03-27 1988-10-04 柳沢 定勝 生体の補填補綴材料
JPS6434371A (en) * 1987-07-31 1989-02-03 Nitta Gelatin Kk Periosteal bone forming material
JPH01158964A (ja) * 1987-09-25 1989-06-22 Collagn Corp 改良された誘導性コラーゲンを主成分とする骨修復調製物
JPH0824710B2 (ja) * 1989-02-23 1996-03-13 ストライカー・コーポレーション 移植用骨コラーゲンマトリックス
WO1996010426A1 (fr) * 1994-09-30 1996-04-11 Yamanouchi Pharmaceutical Co., Ltd. Greffon osteoplastique
WO2004098540A1 (ja) * 1993-09-16 2004-11-18 Hiroyuki Kitamura 歯周病治療材
US6989033B1 (en) 1992-09-17 2006-01-24 Karlheinz Schmidt Implant for recreating verterbrae and tubular bones
US7214654B1 (en) 1994-12-07 2007-05-08 Karlheinz Schmidt Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex
JP2008231091A (ja) * 2006-12-14 2008-10-02 Johnson & Johnson Regenerative Therapeutics Llc タンパク質安定化調合物

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001169A (en) * 1984-10-24 1991-03-19 Collagen Corporation Inductive collagen-based bone repair preparations
JPS61259675A (ja) * 1985-05-15 1986-11-17 三菱マテリアル株式会社 骨欠損部及び空隙部充てん材
DE3521684A1 (de) * 1985-06-18 1986-12-18 Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg Verfahren zur beschichtung von polymeren
JPH0662679B2 (ja) * 1985-06-21 1994-08-17 新田ゼラチン株式会社 組織親和性コラ−ゲンとその製法
DE3612643A1 (de) * 1985-12-05 1987-06-11 Mueller Lierheim Kg Biolog Lab Traegerkoerper, der durch kovalent an seine oberflaeche gebundene antikoerper bioaktiviert ist
US5154931A (en) * 1986-10-22 1992-10-13 Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) Growth-stimulating material derived from porcine bone therefor and a manufacturing process
US5258029A (en) * 1988-09-29 1993-11-02 Collagen Corporation Method for improving implant fixation
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
US5207710A (en) * 1988-09-29 1993-05-04 Collagen Corporation Method for improving implant fixation
FR2637502A1 (fr) * 1988-10-12 1990-04-13 Duroselle Patrick Materiau de xenogreffe osseuse et procede d'obtention
EP0366029B1 (de) * 1988-10-25 1994-09-07 Takao Yamamuro Knochenersatzmaterial und Knochenzement
JPH03151877A (ja) * 1989-06-02 1991-06-28 Chiron Corp 骨カルシウム沈着因子
CA2020729A1 (en) * 1989-07-19 1991-01-20 Michael C. Kiefer Bone morphogenetic protein
US5288628A (en) * 1992-06-24 1994-02-22 The Procter & Gamble Company Rat osteosarcoma cell line OSR4TR1
US5286645A (en) * 1992-06-24 1994-02-15 The Procter & Gamble Company Rat osteosarcoma cell line osr3tr1
US5264358A (en) * 1992-06-24 1993-11-23 The Procter & Gamble Company Rat osteosarcoma cell line OSR9TR1
US5286643A (en) * 1992-06-24 1994-02-15 The Procter & Gamble Company Rat osteosarcoma cell line OSR-8
US5286644A (en) * 1992-06-24 1994-02-15 The Procter & Gamble Company Rat osteosarcoma cell line OSR-2
US5292656A (en) * 1992-06-24 1994-03-08 The Procter & Gamble Company Rat osteosarcoma cell line OSR-6
DE19917696A1 (de) 1999-04-20 2000-10-26 Karlheinz Schmidt Mittel für die Herstellung biologischer Teile mit einem Wirkstoffkomplex und für diesen geeigneten Trägermaterialien
ATE239514T1 (de) * 1997-02-07 2003-05-15 Stryker Corp Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
DE19962248A1 (de) * 1999-12-22 2001-06-28 Tutogen Medical Gmbh Verfahren zur Herstellung eines mit Knochenwachstumsfaktoren angereicherten Knochenmaterials
DE10054857B4 (de) * 2000-11-06 2005-02-17 Bohmann, Anton, Dr.med., Dipl.-Ing. (FH) System zur Herstellung von individuell formbarem Knochenersatz
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218255A (en) * 1976-08-30 1980-08-19 University Of Dayton Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/or other mamillian species and method
DE2807132C2 (de) * 1978-02-20 1983-11-03 Battelle-Institut E.V., 6000 Frankfurt Implantierbares Pharmaka-Depot
CS216992B1 (en) * 1980-07-21 1982-12-31 Miroslav Stol Composite polymere material for the biological and medicinal utilitation and method of preparation thereof
US4294753A (en) * 1980-08-04 1981-10-13 The Regents Of The University Of California Bone morphogenetic protein process
US4430760A (en) * 1981-12-18 1984-02-14 Collagen Corporation Nonstress-bearing implantable bone prosthesis
US4394370A (en) * 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4440750A (en) * 1982-02-12 1984-04-03 Collagen Corporation Osteogenic composition and method
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US4434094A (en) * 1983-04-12 1984-02-28 Collagen Corporation Partially purified osteogenic factor and process for preparing same from demineralized bone

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0555149B2 (de) * 1984-10-24 1993-08-16 Collagen Corp
JPS6216421A (ja) * 1984-10-24 1987-01-24 コラ−ゲン・コ−ポレイシヨン 誘導性コラ−ゲン・ベ−ス骨修復調製物
JPS62135431A (ja) * 1985-12-07 1987-06-18 Katsuyuki Fujii 液状骨形成剤からなる注射液
JPS6365872A (ja) * 1986-09-08 1988-03-24 新田ゼラチン株式会社 骨形成用注入材料
JPS63105765A (ja) * 1986-10-24 1988-05-11 株式会社 アドバンス インプラント
JPS63238867A (ja) * 1987-03-27 1988-10-04 柳沢 定勝 生体の補填補綴材料
JPS6434371A (en) * 1987-07-31 1989-02-03 Nitta Gelatin Kk Periosteal bone forming material
JPH01158964A (ja) * 1987-09-25 1989-06-22 Collagn Corp 改良された誘導性コラーゲンを主成分とする骨修復調製物
JPH0553139B2 (de) * 1987-09-25 1993-08-09 Collagen Corp
JPH0824710B2 (ja) * 1989-02-23 1996-03-13 ストライカー・コーポレーション 移植用骨コラーゲンマトリックス
US6989033B1 (en) 1992-09-17 2006-01-24 Karlheinz Schmidt Implant for recreating verterbrae and tubular bones
WO2004098540A1 (ja) * 1993-09-16 2004-11-18 Hiroyuki Kitamura 歯周病治療材
WO1996010426A1 (fr) * 1994-09-30 1996-04-11 Yamanouchi Pharmaceutical Co., Ltd. Greffon osteoplastique
US7214654B1 (en) 1994-12-07 2007-05-08 Karlheinz Schmidt Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex
JP2008231091A (ja) * 2006-12-14 2008-10-02 Johnson & Johnson Regenerative Therapeutics Llc タンパク質安定化調合物
US8895506B2 (en) 2006-12-14 2014-11-25 DePuy Synthes Products, LLC Protein stabilization formulations

Also Published As

Publication number Publication date
DE3519073A1 (de) 1985-12-19
GB2164042A (en) 1986-03-12
FR2564732A1 (fr) 1985-11-29
GB8513390D0 (en) 1985-07-03
CH667394A5 (de) 1988-10-14
DE3519073C2 (de) 1989-11-23
GB2164042B (en) 1987-10-14
FR2564732B1 (fr) 1990-09-07
JPH0575425B2 (de) 1993-10-20

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