JPS60253455A - 骨形成因子を含有する生体材料とその製造方法 - Google Patents
骨形成因子を含有する生体材料とその製造方法Info
- Publication number
- JPS60253455A JPS60253455A JP59109020A JP10902084A JPS60253455A JP S60253455 A JPS60253455 A JP S60253455A JP 59109020 A JP59109020 A JP 59109020A JP 10902084 A JP10902084 A JP 10902084A JP S60253455 A JPS60253455 A JP S60253455A
- Authority
- JP
- Japan
- Prior art keywords
- bone
- collagen
- biomaterial
- living body
- material containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59109020A JPS60253455A (ja) | 1984-05-28 | 1984-05-28 | 骨形成因子を含有する生体材料とその製造方法 |
GB08513390A GB2164042B (en) | 1984-05-28 | 1985-05-28 | Artificial bone forming composition |
DE19853519073 DE3519073A1 (de) | 1984-05-28 | 1985-05-28 | Kuenstliches knochenerzeugendes biomaterial und verfahren zu seiner herstellung |
CH2249/85A CH667394A5 (de) | 1984-05-28 | 1985-05-28 | Kuenstliches knochenbildendes biomaterial und dieses enthaltendes implantationsmaterial. |
FR858507991A FR2564732B1 (fr) | 1984-05-28 | 1985-05-28 | Biomatiere osteoformatrice artificielle et son procede de fabrication |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59109020A JPS60253455A (ja) | 1984-05-28 | 1984-05-28 | 骨形成因子を含有する生体材料とその製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS60253455A true JPS60253455A (ja) | 1985-12-14 |
JPH0575425B2 JPH0575425B2 (de) | 1993-10-20 |
Family
ID=14499552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59109020A Granted JPS60253455A (ja) | 1984-05-28 | 1984-05-28 | 骨形成因子を含有する生体材料とその製造方法 |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS60253455A (de) |
CH (1) | CH667394A5 (de) |
DE (1) | DE3519073A1 (de) |
FR (1) | FR2564732B1 (de) |
GB (1) | GB2164042B (de) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6216421A (ja) * | 1984-10-24 | 1987-01-24 | コラ−ゲン・コ−ポレイシヨン | 誘導性コラ−ゲン・ベ−ス骨修復調製物 |
JPS62135431A (ja) * | 1985-12-07 | 1987-06-18 | Katsuyuki Fujii | 液状骨形成剤からなる注射液 |
JPS6365872A (ja) * | 1986-09-08 | 1988-03-24 | 新田ゼラチン株式会社 | 骨形成用注入材料 |
JPS63105765A (ja) * | 1986-10-24 | 1988-05-11 | 株式会社 アドバンス | インプラント |
JPS63238867A (ja) * | 1987-03-27 | 1988-10-04 | 柳沢 定勝 | 生体の補填補綴材料 |
JPS6434371A (en) * | 1987-07-31 | 1989-02-03 | Nitta Gelatin Kk | Periosteal bone forming material |
JPH01158964A (ja) * | 1987-09-25 | 1989-06-22 | Collagn Corp | 改良された誘導性コラーゲンを主成分とする骨修復調製物 |
JPH0824710B2 (ja) * | 1989-02-23 | 1996-03-13 | ストライカー・コーポレーション | 移植用骨コラーゲンマトリックス |
WO1996010426A1 (fr) * | 1994-09-30 | 1996-04-11 | Yamanouchi Pharmaceutical Co., Ltd. | Greffon osteoplastique |
WO2004098540A1 (ja) * | 1993-09-16 | 2004-11-18 | Hiroyuki Kitamura | 歯周病治療材 |
US6989033B1 (en) | 1992-09-17 | 2006-01-24 | Karlheinz Schmidt | Implant for recreating verterbrae and tubular bones |
US7214654B1 (en) | 1994-12-07 | 2007-05-08 | Karlheinz Schmidt | Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex |
JP2008231091A (ja) * | 2006-12-14 | 2008-10-02 | Johnson & Johnson Regenerative Therapeutics Llc | タンパク質安定化調合物 |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5001169A (en) * | 1984-10-24 | 1991-03-19 | Collagen Corporation | Inductive collagen-based bone repair preparations |
JPS61259675A (ja) * | 1985-05-15 | 1986-11-17 | 三菱マテリアル株式会社 | 骨欠損部及び空隙部充てん材 |
DE3521684A1 (de) * | 1985-06-18 | 1986-12-18 | Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg | Verfahren zur beschichtung von polymeren |
JPH0662679B2 (ja) * | 1985-06-21 | 1994-08-17 | 新田ゼラチン株式会社 | 組織親和性コラ−ゲンとその製法 |
DE3612643A1 (de) * | 1985-12-05 | 1987-06-11 | Mueller Lierheim Kg Biolog Lab | Traegerkoerper, der durch kovalent an seine oberflaeche gebundene antikoerper bioaktiviert ist |
US5154931A (en) * | 1986-10-22 | 1992-10-13 | Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) | Growth-stimulating material derived from porcine bone therefor and a manufacturing process |
US5258029A (en) * | 1988-09-29 | 1993-11-02 | Collagen Corporation | Method for improving implant fixation |
US5108436A (en) * | 1988-09-29 | 1992-04-28 | Collagen Corporation | Implant fixation |
US5207710A (en) * | 1988-09-29 | 1993-05-04 | Collagen Corporation | Method for improving implant fixation |
FR2637502A1 (fr) * | 1988-10-12 | 1990-04-13 | Duroselle Patrick | Materiau de xenogreffe osseuse et procede d'obtention |
EP0366029B1 (de) * | 1988-10-25 | 1994-09-07 | Takao Yamamuro | Knochenersatzmaterial und Knochenzement |
JPH03151877A (ja) * | 1989-06-02 | 1991-06-28 | Chiron Corp | 骨カルシウム沈着因子 |
CA2020729A1 (en) * | 1989-07-19 | 1991-01-20 | Michael C. Kiefer | Bone morphogenetic protein |
US5288628A (en) * | 1992-06-24 | 1994-02-22 | The Procter & Gamble Company | Rat osteosarcoma cell line OSR4TR1 |
US5286645A (en) * | 1992-06-24 | 1994-02-15 | The Procter & Gamble Company | Rat osteosarcoma cell line osr3tr1 |
US5264358A (en) * | 1992-06-24 | 1993-11-23 | The Procter & Gamble Company | Rat osteosarcoma cell line OSR9TR1 |
US5286643A (en) * | 1992-06-24 | 1994-02-15 | The Procter & Gamble Company | Rat osteosarcoma cell line OSR-8 |
US5286644A (en) * | 1992-06-24 | 1994-02-15 | The Procter & Gamble Company | Rat osteosarcoma cell line OSR-2 |
US5292656A (en) * | 1992-06-24 | 1994-03-08 | The Procter & Gamble Company | Rat osteosarcoma cell line OSR-6 |
DE19917696A1 (de) | 1999-04-20 | 2000-10-26 | Karlheinz Schmidt | Mittel für die Herstellung biologischer Teile mit einem Wirkstoffkomplex und für diesen geeigneten Trägermaterialien |
ATE239514T1 (de) * | 1997-02-07 | 2003-05-15 | Stryker Corp | Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung |
US20040081704A1 (en) | 1998-02-13 | 2004-04-29 | Centerpulse Biologics Inc. | Implantable putty material |
DE19962248A1 (de) * | 1999-12-22 | 2001-06-28 | Tutogen Medical Gmbh | Verfahren zur Herstellung eines mit Knochenwachstumsfaktoren angereicherten Knochenmaterials |
DE10054857B4 (de) * | 2000-11-06 | 2005-02-17 | Bohmann, Anton, Dr.med., Dipl.-Ing. (FH) | System zur Herstellung von individuell formbarem Knochenersatz |
US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
US7166133B2 (en) | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
CN103313733A (zh) | 2010-11-15 | 2013-09-18 | 捷迈整形外科生物材料有限公司 | 骨空隙填充剂 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4218255A (en) * | 1976-08-30 | 1980-08-19 | University Of Dayton | Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/or other mamillian species and method |
DE2807132C2 (de) * | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
CS216992B1 (en) * | 1980-07-21 | 1982-12-31 | Miroslav Stol | Composite polymere material for the biological and medicinal utilitation and method of preparation thereof |
US4294753A (en) * | 1980-08-04 | 1981-10-13 | The Regents Of The University Of California | Bone morphogenetic protein process |
US4430760A (en) * | 1981-12-18 | 1984-02-14 | Collagen Corporation | Nonstress-bearing implantable bone prosthesis |
US4394370A (en) * | 1981-09-21 | 1983-07-19 | Jefferies Steven R | Bone graft material for osseous defects and method of making same |
US4440750A (en) * | 1982-02-12 | 1984-04-03 | Collagen Corporation | Osteogenic composition and method |
IL68218A (en) * | 1983-03-23 | 1985-12-31 | Univ Ramot | Compositions for cartilage repair comprising embryonal chondrocytes |
US4434094A (en) * | 1983-04-12 | 1984-02-28 | Collagen Corporation | Partially purified osteogenic factor and process for preparing same from demineralized bone |
-
1984
- 1984-05-28 JP JP59109020A patent/JPS60253455A/ja active Granted
-
1985
- 1985-05-28 GB GB08513390A patent/GB2164042B/en not_active Expired
- 1985-05-28 CH CH2249/85A patent/CH667394A5/de not_active IP Right Cessation
- 1985-05-28 FR FR858507991A patent/FR2564732B1/fr not_active Expired - Fee Related
- 1985-05-28 DE DE19853519073 patent/DE3519073A1/de active Granted
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0555149B2 (de) * | 1984-10-24 | 1993-08-16 | Collagen Corp | |
JPS6216421A (ja) * | 1984-10-24 | 1987-01-24 | コラ−ゲン・コ−ポレイシヨン | 誘導性コラ−ゲン・ベ−ス骨修復調製物 |
JPS62135431A (ja) * | 1985-12-07 | 1987-06-18 | Katsuyuki Fujii | 液状骨形成剤からなる注射液 |
JPS6365872A (ja) * | 1986-09-08 | 1988-03-24 | 新田ゼラチン株式会社 | 骨形成用注入材料 |
JPS63105765A (ja) * | 1986-10-24 | 1988-05-11 | 株式会社 アドバンス | インプラント |
JPS63238867A (ja) * | 1987-03-27 | 1988-10-04 | 柳沢 定勝 | 生体の補填補綴材料 |
JPS6434371A (en) * | 1987-07-31 | 1989-02-03 | Nitta Gelatin Kk | Periosteal bone forming material |
JPH01158964A (ja) * | 1987-09-25 | 1989-06-22 | Collagn Corp | 改良された誘導性コラーゲンを主成分とする骨修復調製物 |
JPH0553139B2 (de) * | 1987-09-25 | 1993-08-09 | Collagen Corp | |
JPH0824710B2 (ja) * | 1989-02-23 | 1996-03-13 | ストライカー・コーポレーション | 移植用骨コラーゲンマトリックス |
US6989033B1 (en) | 1992-09-17 | 2006-01-24 | Karlheinz Schmidt | Implant for recreating verterbrae and tubular bones |
WO2004098540A1 (ja) * | 1993-09-16 | 2004-11-18 | Hiroyuki Kitamura | 歯周病治療材 |
WO1996010426A1 (fr) * | 1994-09-30 | 1996-04-11 | Yamanouchi Pharmaceutical Co., Ltd. | Greffon osteoplastique |
US7214654B1 (en) | 1994-12-07 | 2007-05-08 | Karlheinz Schmidt | Agent for the manufacture of biological parts including an active ingredient complex and carrying materials suitable for the active ingredient complex |
JP2008231091A (ja) * | 2006-12-14 | 2008-10-02 | Johnson & Johnson Regenerative Therapeutics Llc | タンパク質安定化調合物 |
US8895506B2 (en) | 2006-12-14 | 2014-11-25 | DePuy Synthes Products, LLC | Protein stabilization formulations |
Also Published As
Publication number | Publication date |
---|---|
DE3519073A1 (de) | 1985-12-19 |
GB2164042A (en) | 1986-03-12 |
FR2564732A1 (fr) | 1985-11-29 |
GB8513390D0 (en) | 1985-07-03 |
CH667394A5 (de) | 1988-10-14 |
DE3519073C2 (de) | 1989-11-23 |
GB2164042B (en) | 1987-10-14 |
FR2564732B1 (fr) | 1990-09-07 |
JPH0575425B2 (de) | 1993-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXPY | Cancellation because of completion of term |