JPS6022711B2 - トランス−デカハイドロキノリン誘導体，その製造法，及びそれを含む医薬 - Google Patents

トランス−デカハイドロキノリン誘導体，その製造法，及びそれを含む医薬

Info

Publication number
JPS6022711B2
JPS6022711B2 JP51151456A JP15145676A JPS6022711B2 JP S6022711 B2 JPS6022711 B2 JP S6022711B2 JP 51151456 A JP51151456 A JP 51151456A JP 15145676 A JP15145676 A JP 15145676A JP S6022711 B2 JPS6022711 B2 JP S6022711B2
Authority
JP
Japan
Prior art keywords
trans
decahydroquinoline
general formula
group
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51151456A
Other languages
English (en)
Japanese (ja)
Other versions
JPS52102284A (en
Inventor
モ−リス・プロス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of JPS52102284A publication Critical patent/JPS52102284A/ja
Publication of JPS6022711B2 publication Critical patent/JPS6022711B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP51151456A 1975-12-16 1976-12-15 トランス−デカハイドロキノリン誘導体，その製造法，及びそれを含む医薬 Expired JPS6022711B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB51507/75A GB1515540A (en) 1975-12-16 1975-12-16 4-amino-trans-decahydroquinoline derivatives
GB51507/75 1975-12-16

Publications (2)

Publication Number Publication Date
JPS52102284A JPS52102284A (en) 1977-08-27
JPS6022711B2 true JPS6022711B2 (ja) 1985-06-03

Family

ID=10460296

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51151456A Expired JPS6022711B2 (ja) 1975-12-16 1976-12-15 トランス−デカハイドロキノリン誘導体，その製造法，及びそれを含む医薬

Country Status (28)

Country Link
JP (1) JPS6022711B2 (nl)
AR (1) AR214988A1 (nl)
AT (1) AT357535B (nl)
AU (1) AU509897B2 (nl)
BE (1) BE849431A (nl)
CA (1) CA1077040A (nl)
CH (1) CH618970A5 (nl)
DD (1) DD128709A5 (nl)
DE (1) DE2656678C2 (nl)
DK (1) DK564876A (nl)
ES (1) ES454285A1 (nl)
FI (1) FI63023C (nl)
FR (1) FR2335224A1 (nl)
GB (1) GB1515540A (nl)
HU (1) HU175391B (nl)
IE (1) IE44355B1 (nl)
IT (1) IT1065969B (nl)
MX (1) MX5798E (nl)
NL (1) NL7613629A (nl)
NO (1) NO145916C (nl)
NZ (1) NZ182758A (nl)
OA (1) OA05515A (nl)
PL (1) PL101143B1 (nl)
PT (1) PT65970B (nl)
SE (1) SE434396B (nl)
SU (1) SU633476A3 (nl)
YU (1) YU39980B (nl)
ZA (1) ZA767112B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2592879B1 (fr) * 1986-01-13 1988-04-29 Roussel Uclaf Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant
JP2007530550A (ja) 2004-03-26 2007-11-01 イーライ リリー アンド カンパニー 異脂肪血症を治療するための化合物および方法

Also Published As

Publication number Publication date
AU2032876A (en) 1978-06-15
YU39980B (en) 1985-06-30
FI63023B (fi) 1982-12-31
NZ182758A (en) 1979-03-28
PT65970A (fr) 1977-01-01
AT357535B (de) 1980-07-10
OA05515A (fr) 1981-04-30
ZA767112B (en) 1978-07-26
IT1065969B (it) 1985-03-04
NO145916C (no) 1982-06-23
MX5798E (es) 1984-07-25
BE849431A (fr) 1977-06-15
JPS52102284A (en) 1977-08-27
ES454285A1 (es) 1977-11-16
IE44355B1 (en) 1981-11-04
AU509897B2 (en) 1980-05-29
PT65970B (fr) 1978-06-16
FI763603A (nl) 1977-06-17
NL7613629A (nl) 1977-06-20
HU175391B (hu) 1980-07-28
NO145916B (no) 1982-03-15
CA1077040A (en) 1980-05-06
ATA932076A (de) 1979-12-15
CH618970A5 (en) 1980-08-29
DE2656678C2 (de) 1986-12-04
FR2335224B1 (nl) 1980-03-14
SE7614105L (sv) 1977-06-17
DD128709A5 (de) 1977-12-07
GB1515540A (en) 1978-06-28
YU307176A (en) 1982-08-31
FI63023C (fi) 1983-04-11
IE44355L (en) 1977-06-16
DE2656678A1 (de) 1977-06-30
SE434396B (sv) 1984-07-23
AR214988A1 (es) 1979-08-31
DK564876A (da) 1977-06-17
FR2335224A1 (fr) 1977-07-15
SU633476A3 (ru) 1978-11-15
PL101143B1 (pl) 1978-12-30
NO764251L (nl) 1977-06-17

Similar Documents

Publication Publication Date Title
US4355040A (en) Hypotensive imidazole-5-acetic acid derivatives
RU2067975C1 (ru) 1,2-дигидро-2-оксопиридины, их физиологически приемлемые соли и фармацевтическая композиция
RU2167152C2 (ru) N-замещенные азагетероциклические карбоновые кислоты или их фармацевтически приемлемые соли, способ их получения, фармацевтическая композиция на их основе и способ ингибирования нейрогенного воспаления
EP0170213B1 (en) Glutarimide antianxiety and antihypertensive agents
US4423044A (en) 3,4-Dihydro-5H-2,3-benzodiazepine derivatives and pharmaceutical use thereof
JPH03173867A (ja) 環状アミン化合物
JPH01104069A (ja) １−［（２−ピリミジニアル）アミノアルキル］ピペリジン類、その製造方法およびその医薬への応用
JP4199668B2 (ja) Ｓｓｔ１アンタゴニスト活性を有するピペラジン誘導体
JPH01197469A (ja) ピペリジニル化合物類
JPH0987282A (ja) チアゾール誘導体
HU185422B (en) Process for producing phenyl-azacycloalkanes
JPH0567150B2 (nl)
US4134991A (en) Derivatives of 2-(3-phenyl-2-aminopropionyloxy)-acetic acid
NZ243337A (en) 1-piperidyl substituted quinoline derivatives and pharmaceutical compositions
CS214796B2 (en) Method of making the new derivatives of 4-amino-2-piperidinochinazoline
IE45051B1 (en) 2-substituted-4-amino-6,7-dimethoxy-quinazolines
JPS63295566A (ja) キノキサリノン誘導体
JP2001511798A (ja) オキシド−スクアレンシクラーゼ抑制剤として有用な複素環化合物
TW204347B (nl)
US5753678A (en) Heterocyclic compounds
JPS6022711B2 (ja) トランス−デカハイドロキノリン誘導体，その製造法，及びそれを含む医薬
JPS6399057A (ja) グリシン誘導体
US4173636A (en) Decahydroquinolines, pharmaceutical compositions and methods of use
US6949656B2 (en) Cyclic amine derivatives and use thereof
JPS6130588A (ja) ベンゾ〔ｃ〕〔１，８〕ナフチリジン、その製造方法及びその使用、並びにこれらの化合物を含有する調製剤