JPS6015616B2 - Ｎ−２−（ピロリジニルメチル）置換ベンズアミド誘導体またはその塩類の製造法 - Google Patents

Ｎ−２−（ピロリジニルメチル）置換ベンズアミド誘導体またはその塩類の製造法

Info

Publication number
JPS6015616B2
JPS6015616B2 JP50027573A JP2757375A JPS6015616B2 JP S6015616 B2 JPS6015616 B2 JP S6015616B2 JP 50027573 A JP50027573 A JP 50027573A JP 2757375 A JP2757375 A JP 2757375A JP S6015616 B2 JPS6015616 B2 JP S6015616B2
Authority
JP
Japan
Prior art keywords
pyrrolidinylmethyl
group
formula
hydrogen atom
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP50027573A
Other languages
English (en)
Japanese (ja)
Other versions
JPS50123668A (xx
Inventor
ビユルト− ジエラ−ル
アシエ ジヤツク
クロ−ド モニエ ジヤン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DECHUUDO SHIANTEIFUIIKU E IND DO RIRU DO FURANSU SOC
Original Assignee
DECHUUDO SHIANTEIFUIIKU E IND DO RIRU DO FURANSU SOC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7407535A external-priority patent/FR2262966A1/fr
Priority claimed from FR7503800A external-priority patent/FR2299863B1/fr
Application filed by DECHUUDO SHIANTEIFUIIKU E IND DO RIRU DO FURANSU SOC filed Critical DECHUUDO SHIANTEIFUIIKU E IND DO RIRU DO FURANSU SOC
Publication of JPS50123668A publication Critical patent/JPS50123668A/ja
Publication of JPS6015616B2 publication Critical patent/JPS6015616B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP50027573A 1974-03-05 1975-03-05 Ｎ−２−（ピロリジニルメチル）置換ベンズアミド誘導体またはその塩類の製造法 Expired JPS6015616B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7407535 1974-03-05
FR7407535A FR2262966A1 (en) 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity
FR7503800A FR2299863B1 (fr) 1975-02-07 1975-02-07 Nouveaux N-(Z-pyrrolidiny alkyl) benzamides substitués, leurs dérivés et leur procédé de préparation
FR7503800 1975-02-07

Publications (2)

Publication Number Publication Date
JPS50123668A JPS50123668A (xx) 1975-09-29
JPS6015616B2 true JPS6015616B2 (ja) 1985-04-20

Family

ID=26218210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50027573A Expired JPS6015616B2 (ja) 1974-03-05 1975-03-05 Ｎ−２−（ピロリジニルメチル）置換ベンズアミド誘導体またはその塩類の製造法

Country Status (27)

Country Link
JP (1) JPS6015616B2 (xx)
AR (1) AR206621A1 (xx)
AT (1) AT358570B (xx)
BG (1) BG24666A3 (xx)
CA (1) CA1047504A (xx)
CH (1) CH605794A5 (xx)
CS (1) CS189692B2 (xx)
DD (1) DD119420A5 (xx)
DE (1) DE2507989A1 (xx)
DK (1) DK145377C (xx)
EG (1) EG12577A (xx)
ES (1) ES435274A1 (xx)
FI (1) FI750620A (xx)
GB (1) GB1466822A (xx)
HK (1) HK14078A (xx)
HU (1) HU170637B (xx)
IE (1) IE40818B1 (xx)
IL (1) IL46696A (xx)
LU (1) LU71949A1 (xx)
NL (1) NL7502608A (xx)
NO (1) NO750713L (xx)
OA (1) OA04966A (xx)
PH (1) PH14197A (xx)
PL (1) PL97091B1 (xx)
RO (2) RO72844A (xx)
SE (1) SE411754B (xx)
SU (1) SU609464A3 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186175A (en) * 1977-01-27 1980-03-05 Shionogi & Co Meta-sulphonamidobenzamide derivatives
SE8503054D0 (sv) * 1985-06-19 1985-06-19 Astra Laekemedel Ab Catecholcarboxamides
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
EP0314483A1 (en) * 1987-10-29 1989-05-03 Erbamont, Inc. Preparation of benzamides
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078497A (en) * 1960-12-29 1963-02-26 Leeds And Mieallef Dispensing containers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078497A (en) * 1960-12-29 1963-02-26 Leeds And Mieallef Dispensing containers

Also Published As

Publication number Publication date
SU609464A3 (ru) 1978-05-30
OA04966A (fr) 1980-10-31
AT358570B (de) 1980-09-25
CA1047504A (en) 1979-01-30
ATA160775A (de) 1980-02-15
DK145377B (da) 1982-11-08
SE7502342L (xx) 1975-09-08
ES435274A1 (es) 1976-12-16
CS189692B2 (en) 1979-04-30
DK145377C (da) 1983-04-11
FI750620A (xx) 1975-09-06
JPS50123668A (xx) 1975-09-29
AR206621A1 (es) 1976-08-06
NO750713L (xx) 1975-09-08
IE40818B1 (en) 1979-08-29
IE40818L (en) 1975-09-05
HU170637B (xx) 1977-07-28
DE2507989A1 (de) 1975-09-11
RO72844A (ro) 1981-09-24
BG24666A3 (en) 1978-04-12
DD119420A5 (xx) 1976-04-20
EG12577A (en) 1979-09-30
PH14197A (en) 1981-03-26
DK86975A (xx) 1975-11-03
RO70647A (ro) 1980-04-15
NL7502608A (nl) 1975-09-09
AU7874075A (en) 1976-09-09
PL97091B1 (pl) 1978-02-28
SU609464A1 (xx) 1978-05-30
LU71949A1 (xx) 1976-02-04
IL46696A (en) 1978-07-31
HK14078A (en) 1978-03-23
CH605794A5 (xx) 1978-10-13
SE411754B (sv) 1980-02-04
IL46696A0 (en) 1975-04-25
GB1466822A (en) 1977-03-09

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