JPS60141293A - 新規制癌性抗生物質81−484およびその製造法 - Google Patents

新規制癌性抗生物質81−484およびその製造法

Info

Publication number
JPS60141293A
JPS60141293A JP58245572A JP24557283A JPS60141293A JP S60141293 A JPS60141293 A JP S60141293A JP 58245572 A JP58245572 A JP 58245572A JP 24557283 A JP24557283 A JP 24557283A JP S60141293 A JPS60141293 A JP S60141293A
Authority
JP
Japan
Prior art keywords
antibiotic
methanol
culture
negative
positive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP58245572A
Other languages
English (en)
Japanese (ja)
Inventor
Iwao Umezawa
梅沢 巖
Hiroki Komiyama
寛機 小宮山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Priority to JP58245572A priority Critical patent/JPS60141293A/ja
Priority to GB08412289A priority patent/GB2152028B/en
Priority to DE19843419076 priority patent/DE3419076A1/de
Priority to FR8408539A priority patent/FR2557455B1/fr
Priority to US06/617,470 priority patent/US4550021A/en
Publication of JPS60141293A publication Critical patent/JPS60141293A/ja
Priority to GB08710389A priority patent/GB2188624B/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP58245572A 1983-12-28 1983-12-28 新規制癌性抗生物質81−484およびその製造法 Pending JPS60141293A (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP58245572A JPS60141293A (ja) 1983-12-28 1983-12-28 新規制癌性抗生物質81−484およびその製造法
GB08412289A GB2152028B (en) 1983-12-28 1984-05-14 Antitumor antibiotic
DE19843419076 DE3419076A1 (de) 1983-12-28 1984-05-22 Neues antitumor-antibiotikum 81-484 und seine herstellung
FR8408539A FR2557455B1 (fr) 1983-12-28 1984-05-30 Antibiotique nouveau 81-484 antitumeur et sa production
US06/617,470 US4550021A (en) 1983-12-28 1984-06-05 Antitumor antibiotic 81-484 and process for its production
GB08710389A GB2188624B (en) 1983-12-28 1987-05-01 Preparation of antitumor antibiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58245572A JPS60141293A (ja) 1983-12-28 1983-12-28 新規制癌性抗生物質81−484およびその製造法

Publications (1)

Publication Number Publication Date
JPS60141293A true JPS60141293A (ja) 1985-07-26

Family

ID=17135710

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58245572A Pending JPS60141293A (ja) 1983-12-28 1983-12-28 新規制癌性抗生物質81−484およびその製造法

Country Status (5)

Country Link
US (1) US4550021A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS60141293A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3419076A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2557455B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB2152028B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918100A (en) * 1983-09-12 1990-04-17 Warner-Lambert Company CL-1957B antibiotic compound and its production
US7288396B2 (en) * 2003-09-11 2007-10-30 Kosan Biosciences Incorporated Biosynthetic gene cluster for leptomycins
US7952306B2 (en) * 2007-06-01 2011-05-31 Progress Rail Services Corp Power system with multiple generator units
US7876061B2 (en) * 2007-06-01 2011-01-25 Progress Rail Services Corp. Power system with multiple generator units
CN103789221B (zh) * 2013-04-28 2016-05-04 北京农学院 具有广谱抑菌活性的放线菌及其筛选方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-06-08 1974-02-08
ZW13679A1 (en) * 1978-08-03 1981-02-18 Ici Ltd Streptomyces metabolite
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4283390A (en) * 1979-11-01 1981-08-11 Eli Lilly And Company Antibiotics and process for production thereof
CA1232852A (en) * 1983-09-12 1988-02-16 Gerard C. Hokanson Cl-1957b antibiotic compound and its production

Also Published As

Publication number Publication date
GB2188624B (en) 1988-07-13
DE3419076A1 (de) 1985-07-11
GB8710389D0 (en) 1987-06-03
GB2152028A (en) 1985-07-31
DE3419076C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-08-20
FR2557455A1 (fr) 1985-07-05
GB2188624A (en) 1987-10-07
FR2557455B1 (fr) 1987-08-21
GB8412289D0 (en) 1984-06-20
GB2152028B (en) 1988-09-28
US4550021A (en) 1985-10-29

Similar Documents

Publication Publication Date Title
JPH04352783A (ja) 12員環マクロライド系化合物
JPS61148189A (ja) Cl−1577dおよびcl−1577e抗生/抗腫瘍化合物およびそれらの製法
JPS60141293A (ja) 新規制癌性抗生物質81−484およびその製造法
JPS58111689A (ja) 新抗生物質ピロロマイシンeおよびその製造法
JPS625990A (ja) 抗生物質およびその製造方法
EP0294491A1 (en) Antibiotic yi-hu3 and process for its preparation
JPH0398591A (ja) 抗腫瘍活性を有する新規抗生物質およびその製造方法
JPH05310766A (ja) 新規抗生物質mi481−42f4−a及びその製造方法
JPH0625095B2 (ja) 抗生物質sf−2415物質およびその製造法
KR810000686B1 (ko) 피페리딘 유도체의 제조법
US3021259A (en) Antibiotics pa-1033a and pa-1033b
JPS61170396A (ja) 新規な制癌性抗生物質83−16−aおよびその製造法
JPS61251670A (ja) 新規抗生物質83−16b、cおよびそれらの製造法
JPH0272183A (ja) 抗生物質wk−2057およびその製造方法
JPS5995891A (ja) 新規な制癌性抗生物質80−217およびその製造法
JPS62277378A (ja) カズサマイシンb、その製造法およびその用途
JPH02191291A (ja) 抗生物質ko―3988a並びにko―3988b及びその製造方法
JPS58201990A (ja) 新規抗生物質80−258およびその製造法
JPS58154598A (ja) 新規抗生物質マイシナミシン6およびその製造法
JPS59213398A (ja) 抗生物質メガロミシンc↓1の製造法
JPS63201195A (ja) 抗生物質tm−611b
JPH0398588A (ja) 抗生物質ko―3599aおよびその製造方法
JPS61126092A (ja) 抗生物質tm−591
JPS63107993A (ja) 抗生物質tm−611
JPS61139394A (ja) 新規な抗生物質ss43405d及びその製造法