JPS60130523A - アルギン酸カルシウムを有効成分とする経口医療補助組成物 - Google Patents
アルギン酸カルシウムを有効成分とする経口医療補助組成物Info
- Publication number
- JPS60130523A JPS60130523A JP58238529A JP23852983A JPS60130523A JP S60130523 A JPS60130523 A JP S60130523A JP 58238529 A JP58238529 A JP 58238529A JP 23852983 A JP23852983 A JP 23852983A JP S60130523 A JPS60130523 A JP S60130523A
- Authority
- JP
- Japan
- Prior art keywords
- food
- calcium alginate
- calcium
- group
- alginate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000013305 food Nutrition 0.000 title claims abstract description 30
- 235000013373 food additive Nutrition 0.000 title claims abstract description 8
- 239000002778 food additive Substances 0.000 title claims abstract description 8
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims abstract description 34
- 239000000648 calcium alginate Substances 0.000 claims abstract description 30
- 235000010410 calcium alginate Nutrition 0.000 claims abstract description 30
- 229960002681 calcium alginate Drugs 0.000 claims abstract description 30
- 206010020772 Hypertension Diseases 0.000 claims abstract description 24
- 239000011734 sodium Substances 0.000 abstract description 17
- 229910052708 sodium Inorganic materials 0.000 abstract description 17
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract description 16
- 230000029142 excretion Effects 0.000 abstract description 13
- 235000005911 diet Nutrition 0.000 abstract description 11
- 230000037213 diet Effects 0.000 abstract description 9
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 7
- 239000011575 calcium Substances 0.000 abstract description 6
- 229910052791 calcium Inorganic materials 0.000 abstract description 6
- 235000015110 jellies Nutrition 0.000 abstract description 5
- 239000008274 jelly Substances 0.000 abstract description 5
- 239000000654 additive Substances 0.000 abstract description 4
- 230000000996 additive effect Effects 0.000 abstract description 4
- 239000000843 powder Substances 0.000 abstract description 3
- 230000009291 secondary effect Effects 0.000 abstract description 3
- 239000003381 stabilizer Substances 0.000 abstract description 3
- 239000002562 thickening agent Substances 0.000 abstract description 3
- 239000002775 capsule Substances 0.000 abstract description 2
- 230000000378 dietary effect Effects 0.000 abstract description 2
- 239000002552 dosage form Substances 0.000 abstract 1
- 235000014106 fortified food Nutrition 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 14
- 239000000737 potassium alginate Substances 0.000 description 13
- 235000010408 potassium alginate Nutrition 0.000 description 13
- MZYRDLHIWXQJCQ-YZOKENDUSA-L potassium alginate Chemical compound [K+].[K+].O1[C@@H](C([O-])=O)[C@@H](OC)[C@H](O)[C@H](O)[C@@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@@H](O)[C@H]1O MZYRDLHIWXQJCQ-YZOKENDUSA-L 0.000 description 13
- 235000002639 sodium chloride Nutrition 0.000 description 12
- 241000700159 Rattus Species 0.000 description 10
- 230000036772 blood pressure Effects 0.000 description 10
- 235000019640 taste Nutrition 0.000 description 10
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- 230000004531 blood pressure lowering effect Effects 0.000 description 8
- 229910052500 inorganic mineral Inorganic materials 0.000 description 8
- 235000010755 mineral Nutrition 0.000 description 8
- 239000011707 mineral Substances 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 210000003608 fece Anatomy 0.000 description 6
- 235000021050 feed intake Nutrition 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 6
- 239000011780 sodium chloride Substances 0.000 description 6
- 229910001415 sodium ion Inorganic materials 0.000 description 6
- 210000002700 urine Anatomy 0.000 description 6
- 239000004480 active ingredient Substances 0.000 description 5
- 235000010443 alginic acid Nutrition 0.000 description 5
- 229920000615 alginic acid Polymers 0.000 description 5
- 230000037396 body weight Effects 0.000 description 5
- 235000012054 meals Nutrition 0.000 description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 4
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 4
- 229910001424 calcium ion Inorganic materials 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 235000013402 health food Nutrition 0.000 description 4
- 229910001414 potassium ion Inorganic materials 0.000 description 4
- 235000015598 salt intake Nutrition 0.000 description 4
- 229920001284 acidic polysaccharide Polymers 0.000 description 3
- 150000004805 acidic polysaccharides Chemical class 0.000 description 3
- 238000001467 acupuncture Methods 0.000 description 3
- 235000019658 bitter taste Nutrition 0.000 description 3
- 230000002550 fecal effect Effects 0.000 description 3
- 230000037406 food intake Effects 0.000 description 3
- 238000005342 ion exchange Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 230000004580 weight loss Effects 0.000 description 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 2
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 2
- 108091006629 SLC13A2 Proteins 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- 229940072056 alginate Drugs 0.000 description 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 238000001479 atomic absorption spectroscopy Methods 0.000 description 2
- 239000005018 casein Substances 0.000 description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 2
- 235000021240 caseins Nutrition 0.000 description 2
- 230000001364 causal effect Effects 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000010411 cooking Methods 0.000 description 2
- 235000021185 dessert Nutrition 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 description 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 description 2
- 229960005135 eicosapentaenoic acid Drugs 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 235000015243 ice cream Nutrition 0.000 description 2
- 229910001425 magnesium ion Inorganic materials 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 235000011962 puddings Nutrition 0.000 description 2
- 238000011699 spontaneously hypertensive rat Methods 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- -1 thorium ions Chemical class 0.000 description 2
- WEQHQGJDZLDFID-UHFFFAOYSA-J thorium(iv) chloride Chemical compound Cl[Th](Cl)(Cl)Cl WEQHQGJDZLDFID-UHFFFAOYSA-J 0.000 description 2
- 230000002485 urinary effect Effects 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- 235000016068 Berberis vulgaris Nutrition 0.000 description 1
- 241000335053 Beta vulgaris Species 0.000 description 1
- 208000031648 Body Weight Changes Diseases 0.000 description 1
- 235000011293 Brassica napus Nutrition 0.000 description 1
- 240000008100 Brassica rapa Species 0.000 description 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 235000019687 Lamb Nutrition 0.000 description 1
- 229910052776 Thorium Inorganic materials 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- LFYJSSARVMHQJB-QIXNEVBVSA-N bakuchiol Chemical compound CC(C)=CCC[C@@](C)(C=C)\C=C\C1=CC=C(O)C=C1 LFYJSSARVMHQJB-QIXNEVBVSA-N 0.000 description 1
- 230000004579 body weight change Effects 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000020939 nutritional additive Nutrition 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 235000000891 standard diet Nutrition 0.000 description 1
- 230000036325 urinary excretion Effects 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
Landscapes
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58238529A JPS60130523A (ja) | 1983-12-16 | 1983-12-16 | アルギン酸カルシウムを有効成分とする経口医療補助組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58238529A JPS60130523A (ja) | 1983-12-16 | 1983-12-16 | アルギン酸カルシウムを有効成分とする経口医療補助組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60130523A true JPS60130523A (ja) | 1985-07-12 |
| JPH0338253B2 JPH0338253B2 (OSRAM) | 1991-06-10 |
Family
ID=17031605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58238529A Granted JPS60130523A (ja) | 1983-12-16 | 1983-12-16 | アルギン酸カルシウムを有効成分とする経口医療補助組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60130523A (OSRAM) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983582A (en) * | 1987-02-13 | 1991-01-08 | Kao Corporation | Preventive and therapeutic method for hypertension |
| WO1991010436A1 (en) * | 1990-01-09 | 1991-07-25 | Kabushiki Kaisha Advance | Salt eliminant composition |
| JP2019013244A (ja) * | 2017-07-03 | 2019-01-31 | トイメディカル株式会社 | ナトリウム排出を目的とした食品組成物 |
| JPWO2020241650A1 (OSRAM) * | 2019-05-28 | 2020-12-03 | ||
| JP2023149652A (ja) * | 2022-03-31 | 2023-10-13 | 博也 古田 | ナトリウム吸着性固形状物の製造方法及び該固形状物を含む排塩用食品組成物 |
| JP2025078039A (ja) * | 2023-11-06 | 2025-05-19 | 一般社団法人健大トランスレーショナルリサーチセンター | アルギン酸カルシウム粉末を含む血中へのナトリウムイオン吸収抑制剤、及びそれを用いた経口摂取製品 |
-
1983
- 1983-12-16 JP JP58238529A patent/JPS60130523A/ja active Granted
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983582A (en) * | 1987-02-13 | 1991-01-08 | Kao Corporation | Preventive and therapeutic method for hypertension |
| WO1991010436A1 (en) * | 1990-01-09 | 1991-07-25 | Kabushiki Kaisha Advance | Salt eliminant composition |
| JP2019013244A (ja) * | 2017-07-03 | 2019-01-31 | トイメディカル株式会社 | ナトリウム排出を目的とした食品組成物 |
| JP2019013221A (ja) * | 2017-07-03 | 2019-01-31 | トイメディカル株式会社 | ナトリウム排出を目的とした食品組成物 |
| JP2019013220A (ja) * | 2017-07-03 | 2019-01-31 | トイメディカル株式会社 | ナトリウム排出を目的とした食品組成物 |
| JPWO2020241650A1 (OSRAM) * | 2019-05-28 | 2020-12-03 | ||
| WO2020241650A1 (ja) * | 2019-05-28 | 2020-12-03 | トイメディカル株式会社 | ナトリウム排出粒子 |
| EP3977865A4 (en) * | 2019-05-28 | 2023-02-01 | Toymedical Co., Ltd. | SODIUM EXCRETION PARTICLES |
| JP2023149652A (ja) * | 2022-03-31 | 2023-10-13 | 博也 古田 | ナトリウム吸着性固形状物の製造方法及び該固形状物を含む排塩用食品組成物 |
| JP2025078039A (ja) * | 2023-11-06 | 2025-05-19 | 一般社団法人健大トランスレーショナルリサーチセンター | アルギン酸カルシウム粉末を含む血中へのナトリウムイオン吸収抑制剤、及びそれを用いた経口摂取製品 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0338253B2 (OSRAM) | 1991-06-10 |
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