JPS5995231A - 光学活性化合物の製造方法 - Google Patents

光学活性化合物の製造方法

Info

Publication number
JPS5995231A
JPS5995231A JP58197725A JP19772583A JPS5995231A JP S5995231 A JPS5995231 A JP S5995231A JP 58197725 A JP58197725 A JP 58197725A JP 19772583 A JP19772583 A JP 19772583A JP S5995231 A JPS5995231 A JP S5995231A
Authority
JP
Japan
Prior art keywords
compound
formula
general formula
ether
tocopherol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58197725A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0428248B2 (enExample
Inventor
リチヤ−ド・バ−ナ−
ヨゼフ・ヒユプシヤ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5995231A publication Critical patent/JPS5995231A/ja
Publication of JPH0428248B2 publication Critical patent/JPH0428248B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Optical Integrated Circuits (AREA)
  • Glass Compositions (AREA)
JP58197725A 1982-10-27 1983-10-24 光学活性化合物の製造方法 Granted JPS5995231A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH6270/82-1 1982-10-27
CH627082 1982-10-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3302776A Division JPH0639468B2 (ja) 1982-10-27 1991-10-23 ヒドロキノン誘導体

Publications (2)

Publication Number Publication Date
JPS5995231A true JPS5995231A (ja) 1984-06-01
JPH0428248B2 JPH0428248B2 (enExample) 1992-05-13

Family

ID=4306940

Family Applications (2)

Application Number Title Priority Date Filing Date
JP58197725A Granted JPS5995231A (ja) 1982-10-27 1983-10-24 光学活性化合物の製造方法
JP3302776A Expired - Lifetime JPH0639468B2 (ja) 1982-10-27 1991-10-23 ヒドロキノン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3302776A Expired - Lifetime JPH0639468B2 (ja) 1982-10-27 1991-10-23 ヒドロキノン誘導体

Country Status (6)

Country Link
US (1) US4559407A (enExample)
EP (1) EP0107806B1 (enExample)
JP (2) JPS5995231A (enExample)
AT (1) ATE43339T1 (enExample)
DE (1) DE3379904D1 (enExample)
DK (1) DK449983A (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170773B1 (da) * 1983-06-21 1996-01-15 Hoffmann La Roche Fremgangsmåde til fremstilling af d-alfa-tocopherol
DK354085A (da) * 1984-08-28 1986-03-01 Hoffmann La Roche Fremgangsmaade til fremstilling af optisk aktive forbindelser
US5034546A (en) * 1986-11-28 1991-07-23 Hoffmann-La Roche Inc. Novel vitamin E intermediates and a process for their manufacture and conversion into vitamin E
DK559887A (da) * 1986-11-28 1988-05-29 Hoffmann La Roche Fremgangsmaade til fremstilling af carbinolderivater
US5600029A (en) * 1994-03-09 1997-02-04 Takeda Chemical Industries, Ltd. Process for producing DL-tocopherols and intermediates therefor
EA035619B1 (ru) 2005-06-01 2020-07-16 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Композиции для использования в способе лечения митохондриальных нарушений
EP2332534B1 (en) * 2006-02-22 2018-11-14 Bioelectron Technology Corporation Phenol and benzoquinone derivatives for use in the treatment of mitochondrial diseases and modulation of energy biomarkers
EP1986636B1 (en) 2006-02-22 2013-04-24 Edison Pharmaceuticals, Inc. Phenol and 1,4-benzoquinone derivatives for use in the treatment of mitochondrial diseases
EP2344142B1 (en) 2008-09-10 2024-06-26 PTC Therapeutics, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
EP3389646A1 (en) 2015-12-17 2018-10-24 BioElectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57136582A (en) * 1981-02-19 1982-08-23 Eisai Co Ltd Preparation of optically active alpha-tocopherol

Also Published As

Publication number Publication date
JPH054981A (ja) 1993-01-14
EP0107806B1 (de) 1989-05-24
DE3379904D1 (en) 1989-06-29
EP0107806A1 (de) 1984-05-09
JPH0428248B2 (enExample) 1992-05-13
DK449983D0 (da) 1983-09-29
DK449983A (da) 1984-04-28
US4559407A (en) 1985-12-17
ATE43339T1 (de) 1989-06-15
JPH0639468B2 (ja) 1994-05-25

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