JPS59163390A - (1,2−ジフエニル−エチレンジアミン)−白金(2)−錯化合物、その製法および該化合物を含有する抗腫瘍作用を有する医薬 - Google Patents
(1,2−ジフエニル−エチレンジアミン)−白金(2)−錯化合物、その製法および該化合物を含有する抗腫瘍作用を有する医薬Info
- Publication number
- JPS59163390A JPS59163390A JP59027402A JP2740284A JPS59163390A JP S59163390 A JPS59163390 A JP S59163390A JP 59027402 A JP59027402 A JP 59027402A JP 2740284 A JP2740284 A JP 2740284A JP S59163390 A JPS59163390 A JP S59163390A
- Authority
- JP
- Japan
- Prior art keywords
- group
- platinum
- groups
- acid
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3305636.6 | 1983-02-18 | ||
DE3305636 | 1983-02-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS59163390A true JPS59163390A (ja) | 1984-09-14 |
JPH047356B2 JPH047356B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-02-10 |
Family
ID=6191190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59027402A Granted JPS59163390A (ja) | 1983-02-18 | 1984-02-17 | (1,2−ジフエニル−エチレンジアミン)−白金(2)−錯化合物、その製法および該化合物を含有する抗腫瘍作用を有する医薬 |
Country Status (11)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61194095A (ja) * | 1985-02-23 | 1986-08-28 | アスタ・メディカ・アクチエンゲゼルシャフト | (1,2‐ジフエニル‐エチレンジアミン)‐白金(2)錯体、その製法及び該化合物を含有する抗腫瘍剤 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA86704B (en) * | 1985-02-23 | 1986-10-29 | Asta Werke Ag Chem Fab | Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes |
US4737589A (en) * | 1985-08-27 | 1988-04-12 | Nippon Kayaku Kabushiki Kaisha | Platinum Complexes |
JPH0665648B2 (ja) * | 1985-09-25 | 1994-08-24 | 塩野義製薬株式会社 | 白金系抗癌物質の安定な凍結真空乾燥製剤 |
JPS63203692A (ja) * | 1987-02-19 | 1988-08-23 | Nippon Kayaku Co Ltd | 新規白金錯体 |
US20050070872A1 (en) * | 2001-12-28 | 2005-03-31 | Kenichi Sato | Blood bag system and method of inactivating pathogenic microorganisms |
US9446393B2 (en) | 2012-07-27 | 2016-09-20 | The Texas A&M University System | Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4339437A (en) * | 1976-12-27 | 1982-07-13 | Research Corporation | Anti-tumor method |
GB2019399A (en) * | 1978-04-04 | 1979-10-31 | Johnson Matthey Co Ltd | Compositions Containing Platinum |
SE7903361L (sv) * | 1978-04-20 | 1979-10-21 | Johnson Matthey Co Ltd | Kompositioner innehallande platina |
NL7807334A (nl) * | 1978-07-06 | 1980-01-08 | Tno | Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel. |
CA1154785A (en) * | 1979-06-20 | 1983-10-04 | Eric W. Stern | Cis-platinum(ii) amine ascorbate complexes |
US4271085A (en) * | 1979-06-20 | 1981-06-02 | Engelhard Minerals & Chemicals Corporation | Cis-platinum (II) amine lactate complexes |
NL181434C (nl) * | 1980-01-03 | 1987-08-17 | Tno | Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing. |
JPS56103192A (en) * | 1980-01-18 | 1981-08-18 | Yoshinori Kitani | Novel platinum complex |
FR2473946A1 (fr) * | 1980-01-21 | 1981-07-24 | Sanson Joseph | Procede de fabrication de sieges ou de coussins en mousse de matiere plastique a housse integree et a ossature prefabriquee incorporee, et installation pour la mise en oeuvre de ce procede |
JPS5716895A (en) * | 1980-07-05 | 1982-01-28 | Otsuka Chem Co Ltd | Platinum 2 complex and antitumor agent containing the same as active principle |
JPS57156416A (en) * | 1981-03-24 | 1982-09-27 | Otsuka Chem Co Ltd | Platinum (2) complex and antitumor agent comprising it as active ingredient |
-
1984
- 1984-02-15 US US06/580,238 patent/US4598091A/en not_active Expired - Fee Related
- 1984-02-16 DE DE8484101581T patent/DE3463771D1/de not_active Expired
- 1984-02-16 EP EP84101581A patent/EP0116955B1/de not_active Expired
- 1984-02-16 AT AT84101581T patent/ATE27279T1/de active
- 1984-02-17 DK DK075584A patent/DK167764B1/da not_active IP Right Cessation
- 1984-02-17 JP JP59027402A patent/JPS59163390A/ja active Granted
- 1984-02-17 HU HU84635A patent/HU192977B/hu unknown
- 1984-02-17 FI FI840660A patent/FI840660A7/fi not_active Application Discontinuation
- 1984-02-17 NO NO840599A patent/NO840599L/no unknown
- 1984-02-17 CA CA000447679A patent/CA1230604A/en not_active Expired
- 1984-02-17 ES ES529810A patent/ES529810A0/es active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61194095A (ja) * | 1985-02-23 | 1986-08-28 | アスタ・メディカ・アクチエンゲゼルシャフト | (1,2‐ジフエニル‐エチレンジアミン)‐白金(2)錯体、その製法及び該化合物を含有する抗腫瘍剤 |
Also Published As
Publication number | Publication date |
---|---|
DK75584A (da) | 1984-08-19 |
NO840599L (no) | 1984-08-20 |
HUT34213A (en) | 1985-02-28 |
FI840660L (fi) | 1984-08-19 |
DK167764B1 (da) | 1993-12-13 |
CA1230604A (en) | 1987-12-22 |
EP0116955A3 (en) | 1984-10-17 |
DK75584D0 (da) | 1984-02-17 |
JPH047356B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-02-10 |
DE3463771D1 (en) | 1987-06-25 |
EP0116955A2 (de) | 1984-08-29 |
US4598091A (en) | 1986-07-01 |
ES8500883A1 (es) | 1984-11-01 |
HU192977B (en) | 1987-08-28 |
ES529810A0 (es) | 1984-11-01 |
EP0116955B1 (de) | 1987-05-20 |
FI840660A0 (fi) | 1984-02-17 |
ATE27279T1 (de) | 1987-06-15 |
FI840660A7 (fi) | 1984-08-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0324154B1 (de) | 1,2-Bis(aminomethyl)cyclobutan-Platin-Komplexe | |
CN105452265B (zh) | 用于治疗肿瘤性疾病尤其具有高her2蛋白水平的肿瘤性疾病的他莫昔芬衍生物 | |
US5275827A (en) | Cis-platinum complexes with chelating amines and sulphinyl carboxylates | |
JPS60209595A (ja) | 抗腫瘍性白金錯体 | |
HU206220B (en) | Process for producing platinum(ii) complexes and pharmaceutical compositions comprising such compounds as active ingredient | |
KR950008372B1 (ko) | 항 종양성 백금 착체, 그의 제법 및 치료에의 이용 | |
JPS59163390A (ja) | (1,2−ジフエニル−エチレンジアミン)−白金(2)−錯化合物、その製法および該化合物を含有する抗腫瘍作用を有する医薬 | |
JPS62246589A (ja) | 〔2,2−ビス(アミノメチル)−1,3−プロパンジオ−ル−n,n’〕白金錯塩 | |
DE69105859T2 (de) | Thioharnstoffderivate und sie enthaltendes antimikrobielles Mittel und sie enthaltendes Mittel gegen Magengeschwüre. | |
CN103214422A (zh) | 一类新型取代胺基咪唑酮衍生物的制备方法及抗癌作用 | |
JPH04501263A (ja) | 新規な4―メチル―5―[2―(4―フェニルピペラジン―1―イル)エチル]チアゾール誘導体、それらの製造法およびそれらを含有する医薬組成物 | |
JPH07112994A (ja) | 白金錯体(iiおよびiv)、置換フェニルアルキル−エチレン−ジアミン、白金錯体(iiおよびiv)の製造方法、置換フェニルアルキル−エチレン−ジアミンの製造方法、この錯体を含有する抗腫瘍作用を有する医薬ならびにこれを含有する溶液、エマルションおよび懸濁液、および、その製造方法 | |
US6001872A (en) | Water soluble transplatinum complexes with anti-cancer activity and method of using same | |
US5130308A (en) | Method of treating hormone dependent tumors with diamine-platinum (ii) complex compounds | |
US7390915B1 (en) | Phosphine transition metal complex having ferrocene skeleton, process for making the same, and anti-cancer agent | |
DE3405611A1 (de) | (1,2-diphenyl-ethylendiamin)-platin(ii)-komplexverbindungen | |
CN112585149B (zh) | 膦过渡金属配位化合物、其制造方法和抗癌剂 | |
JPS6147452A (ja) | エチレンジアミン誘導体及びその製造方法 | |
US4996227A (en) | 3-(heteroarylalkyene)- and 3-(arylalkylene)-2,4(3H,5H)-heterocyclic diones as cancer chemotherapy drugs | |
Seebacher et al. | Tetrahydropyridinylidene ammonium salts with arylalkyl and diarylalkyl substitution and their antiprotozoal activity | |
JPWO2016208481A1 (ja) | 新規白金(iv)錯体 | |
Kabuloglu Karayusuf | Cisplatin analogues containing 4, 4'-bis [alkyl]-2, 2'-bipyridine derivatives | |
CN111269182A (zh) | 3-氮杂双环[5.2.0]类化合物及其合成方法和应用 | |
TWI278455B (en) | Novel xanthone compounds, their preparation and use as medicament | |
JP2007308437A (ja) | フェロセン骨格を有するホスフィン遷移金属錯体、その製造方法及び抗癌剤 |