JPS5896095A - １１−ｏ−アルキルエリスロマイシンａ誘導体 - Google Patents

１１−ｏ−アルキルエリスロマイシンａ誘導体

Info

Publication number
JPS5896095A
JPS5896095A JP56192294A JP19229481A JPS5896095A JP S5896095 A JPS5896095 A JP S5896095A JP 56192294 A JP56192294 A JP 56192294A JP 19229481 A JP19229481 A JP 19229481A JP S5896095 A JPS5896095 A JP S5896095A
Authority
JP
Japan
Prior art keywords
compound
erythromycin
solvent
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56192294A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6360031B2 (en, 2012
Inventor
Shigeo Morimoto
森本　繁夫
Yoko Takahashi
洋子 高橋
Yoshiaki Watanabe
渡辺　慶昭
Sadafumi Omura
大村　貞文
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Priority to JP56192294A priority Critical patent/JPS5896095A/ja
Priority to DE8282306036T priority patent/DE3261977D1/de
Priority to EP82306036A priority patent/EP0080819B1/en
Publication of JPS5896095A publication Critical patent/JPS5896095A/ja
Publication of JPS6360031B2 publication Critical patent/JPS6360031B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56192294A 1981-11-30 1981-11-30 １１−ｏ−アルキルエリスロマイシンａ誘導体 Granted JPS5896095A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP56192294A JPS5896095A (ja) 1981-11-30 1981-11-30 １１−ｏ−アルキルエリスロマイシンａ誘導体
DE8282306036T DE3261977D1 (en) 1981-11-30 1982-11-12 11-0-alkylerythromycin a derivatives
EP82306036A EP0080819B1 (en) 1981-11-30 1982-11-12 11-0-alkylerythromycin a derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56192294A JPS5896095A (ja) 1981-11-30 1981-11-30 １１−ｏ−アルキルエリスロマイシンａ誘導体

Publications (2)

Publication Number Publication Date
JPS5896095A true JPS5896095A (ja) 1983-06-07
JPS6360031B2 JPS6360031B2 (en, 2012) 1988-11-22

Family

ID=16288878

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56192294A Granted JPS5896095A (ja) 1981-11-30 1981-11-30 １１−ｏ−アルキルエリスロマイシンａ誘導体

Country Status (3)

Country Link
EP (1) EP0080819B1 (en, 2012)
JP (1) JPS5896095A (en, 2012)
DE (1) DE3261977D1 (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007502857A (ja) * 2003-05-30 2007-02-15 プリヴァ−イストラジヴァキ・インスティトゥ・ディー・オー・オー Ｏ−アルキルマクロライドおよびｏ−アルキルアザリド誘導体、およびそれらを調製するためのレギオ選択的方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60120895A (ja) * 1983-12-02 1985-06-28 Taisho Pharmaceut Co Ltd ６−０−メチル−２′−０，ν−ビス（ベンジルオキシカルボニル）−ν−デメチルエリスロマイシンａの製法
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
IL75908A0 (en) * 1984-08-31 1985-12-31 Abbott Lab Macrolide alkylation process
US4847242A (en) 1985-03-12 1989-07-11 Beecham Group P.L.C. 11-ether derivatives of erythromycins
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−ｎ−メチルエリスロマイシン誘導体
US4640910A (en) * 1985-11-12 1987-02-03 Abbott Laboratories Erythromycin A silylated compounds and method of use
DE3782994T2 (de) 1986-09-18 1993-04-08 Taisho Pharma Co Ltd Erythromycin-a-derivate und verfahren zu ihrer herstellung.
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5929219A (en) 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
AU2003267675A1 (en) * 2003-09-02 2005-03-16 Pliva - Istrazivacki Institut D.O.O. O-alkyl macrolide and azalide derivatives and regioselective process for their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3884904A (en) * 1973-06-21 1975-05-20 Abbott Lab 11-Substituted erythromycin B derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007502857A (ja) * 2003-05-30 2007-02-15 プリヴァ−イストラジヴァキ・インスティトゥ・ディー・オー・オー Ｏ−アルキルマクロライドおよびｏ−アルキルアザリド誘導体、およびそれらを調製するためのレギオ選択的方法

Also Published As

Publication number Publication date
EP0080819B1 (en) 1985-01-16
DE3261977D1 (en) 1985-02-28
JPS6360031B2 (en, 2012) 1988-11-22
EP0080819A1 (en) 1983-06-08

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