JPS5874620A - Ｘ線造影剤の耐性を増加する方法、およびそれによつて得られる造影剤 - Google Patents

Ｘ線造影剤の耐性を増加する方法、およびそれによつて得られる造影剤

Info

Publication number
JPS5874620A
JPS5874620A JP57149833A JP14983382A JPS5874620A JP S5874620 A JPS5874620 A JP S5874620A JP 57149833 A JP57149833 A JP 57149833A JP 14983382 A JP14983382 A JP 14983382A JP S5874620 A JPS5874620 A JP S5874620A
Authority
JP
Japan
Prior art keywords
group
formula
compound
iodine
bromine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57149833A
Other languages
English (en)
Japanese (ja)
Inventor
イオアナ・デイモ
ブルノ・ボンマイン
ミシエル・ジヤン−シヤルル・アルドウイン
ジヤン・ロウトロウ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guerbet SA
Original Assignee
Guerbet SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet SA filed Critical Guerbet SA
Publication of JPS5874620A publication Critical patent/JPS5874620A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/90—In vivo diagnostic or in vivo test agent which contains an additional ingredient to reduce the toxicity or side effects of the active ingredient

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Table Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP57149833A 1981-08-28 1982-08-28 Ｘ線造影剤の耐性を増加する方法、およびそれによつて得られる造影剤 Pending JPS5874620A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8116478A FR2511871A1 (fr) 1981-08-28 1981-08-28 Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus
FR8116478 1981-08-28

Publications (1)

Publication Number Publication Date
JPS5874620A true JPS5874620A (ja) 1983-05-06

Family

ID=9261753

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57149833A Pending JPS5874620A (ja) 1981-08-28 1982-08-28 Ｘ線造影剤の耐性を増加する方法、およびそれによつて得られる造影剤

Country Status (9)

Country Link
US (1) US4474747A (enExample)
EP (1) EP0074309A1 (enExample)
JP (1) JPS5874620A (enExample)
AU (1) AU8747482A (enExample)
DK (1) DK383782A (enExample)
FI (1) FI822979L (enExample)
FR (1) FR2511871A1 (enExample)
NO (1) NO822908L (enExample)
ZA (1) ZA826033B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4801661B2 (ja) * 2005-03-18 2011-10-26 マナック株式会社 ５−アミノ−２，４，６−トリヨードイソフタル酸誘導体のアセチル化方法

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204086A (en) * 1982-10-01 1993-04-20 Nycomed Imaging As X-ray contrast agent
JPS59104352A (ja) * 1982-11-08 1984-06-16 ニユエガ−ド・アンド・コンパニ−・アクシエ・セルカペト Ｘ線造影剤
JPH0625094B2 (ja) * 1988-03-01 1994-04-06 マリンクロット，インコーポレイテッド 非イオン性ｘ線コントラスト剤、組成物及び方法
US5043152A (en) * 1988-06-02 1991-08-27 Guerbet S.A. Novel iodinated non-ionic triiodobenzene compounds and contrast media containing them
US5143715A (en) * 1990-03-28 1992-09-01 Molecular Biosystems, Inc. Organic contrast agent analog and method of making same
US5250283A (en) * 1990-03-28 1993-10-05 Molecular Biosystems, Inc. Organic contrast agent analog and method of making same
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5622687A (en) * 1994-11-15 1997-04-22 Molecular Biosystems, Inc. Calixarene conjugates useful as MRI and CT diagnostic imaging agents
US5668196A (en) * 1995-08-10 1997-09-16 Nanosystems Llc 3-amido-triiodophenyl esters as x-ray contrast agents
US6751290B2 (en) 1998-09-08 2004-06-15 Veritas Pharmaceuticals, Inc. Radiographic assessment of tissue after exposure to a compound
US20010038682A1 (en) * 1998-09-08 2001-11-08 Jesse Salb Radiographic assessment of tissue response to compounds
US6723746B2 (en) 1998-09-08 2004-04-20 Veritas Pharmaceuticals, Inc. Functional radiographic imaging methods and agents
US6226352B1 (en) * 1998-09-08 2001-05-01 Veritas Pharmaceuticals, Inc. System and method for radiographic imaging of tissue
US6265610B1 (en) 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
ATE450201T1 (de) 2000-03-16 2009-12-15 Veritas Pharmaceuticals Radiographische bewertung von gewebereaktionen auf chemische verbindungen
EP1186305A1 (en) * 2000-09-07 2002-03-13 Schering Aktiengesellschaft New brominated compounds as contrast media for X-ray mammography
US7378081B2 (en) 2003-01-29 2008-05-27 Vincon Research Enterprises, Llc Composition and method for direct visualization of the human appendix
EP2253332B1 (en) * 2004-03-11 2012-10-10 Mallinckrodt LLC Low osmolar x-ray contrast media formulations
MX2014001623A (es) 2011-08-10 2015-03-09 Digna Biotech Sl Uso de la cardiotofina-1 para el tratamiento de enfermedades renales.
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2162E (fr) * 1904-01-14 Andre Louis Veluard Dispositifs permettant la fabrication mécanique et continue du plumetis sur métiers à tisser de tous systèmes et pour tous genres de tissus
FR820E (fr) * 1900-03-26 1903-04-02 Denayrouze Louis Briquette de chauffage à l'alcool et autres liquides volatils combustibles, à charge renouvelable
US1870203A (en) * 1930-03-26 1932-08-02 Firm Schering Kahlbaum A G Compounds of the pyridine series
US2580459A (en) * 1946-11-27 1952-01-01 Schering Corp Production of halogenated aryl fatty acids
US2524827A (en) * 1948-05-13 1950-10-10 Schering Corp Halogen substituted polycyclic aryl aliphatic acids
NL74787C (enExample) * 1950-11-13
FR1088590A (fr) * 1952-08-16 1955-03-08 Schering Ag Agents de contraste pour rayons x et leur préparation
US2813118A (en) * 1953-07-16 1957-11-12 American Cystoscope Makers Inc X-ray contrast compounds
US3076024A (en) * 1954-02-19 1963-01-29 Sterling Drug Inc Acylated 3, 5-diaminopolyhalobenzoic acids
US2890244A (en) * 1956-09-07 1959-06-09 Endopharm Frankfurter Arzneimi 2, 4, 6-tribromo-3-acetylaminobenzoic acid and salts thereof
US3009952A (en) * 1957-04-17 1961-11-21 Sterling Drug Inc Preparation of halogenated isophthalic acids
BR6024559D0 (pt) * 1959-12-08 1973-05-31 Nyegaard & Co As Processo para preparacao de novos derivados de acido 3 5-diamino-2 4 6-triiodo benzoico ou semi sais nao toxicos bem como de agentes ou meios de contraste para raios x baseados nos mesmos
FR2162M (fr) * 1961-02-28 1963-11-25 Nyegaard & Co As Dérivés de n-alkylacylanilides, utiles, notamment comme agents de contraste pour rayons x.
US3290366A (en) * 1963-03-06 1966-12-06 Mallinckrodt Chemical Works 5-amino-nu-alkyl-2, 4, 6-triiodoisophthalamic acid derivatives
FR2074734A1 (en) * 1970-01-22 1971-10-08 Guerbet Lab Andre 3-(n-2-hydroxyethylcarbamyl)-5-(n-methylacetamido)2,4,6-triiodo- benz - acid - radiographic contrast agent
FR2085636B1 (enExample) * 1970-04-15 1973-06-08 Guerbet Lab Andre
GB1436357A (en) * 1973-12-07 1976-05-19 Laboraoires Andre Guerbet Tri-iodo benzene derivatives and their use as x-ray contrast
AR207465A1 (es) * 1974-05-31 1976-10-08 Guerbet Lab Andre Procedimiento de preparacion de derivados de acido triiodoi2,4,6-(triiodo-2,4,6-benzoil)-amino-alcanoilaminobenzoico de acido triiodo-2,4,6-(triiodo-2,4,6-(triiodo-2,4,6-benzoil)-aminoalcanoilaminobenzoil)-amino-alcanoil-aminobenzoico y de acido triiodo-2,4,6-bis((triiodo-2,4,6-fenil)-carbamoil-metil)-aminoalcanoil-aminobenzoico
US4073879A (en) * 1974-08-26 1978-02-14 University Of Illinois Foundation Brominated perfluorocarbon radiopaque agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4801661B2 (ja) * 2005-03-18 2011-10-26 マナック株式会社 ５−アミノ−２，４，６−トリヨードイソフタル酸誘導体のアセチル化方法

Also Published As

Publication number Publication date
FI822979A7 (fi) 1983-03-01
US4474747A (en) 1984-10-02
FR2511871B1 (enExample) 1983-12-23
AU8747482A (en) 1983-03-03
FR2511871A1 (fr) 1983-03-04
NO822908L (no) 1983-03-01
EP0074309A1 (fr) 1983-03-16
FI822979L (fi) 1983-03-01
ZA826033B (en) 1984-03-28
DK383782A (da) 1983-03-01
FI822979A0 (fi) 1982-08-27

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