FR2511871A1 - Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus - Google Patents

Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus Download PDF

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Publication number
FR2511871A1
FR2511871A1 FR8116478A FR8116478A FR2511871A1 FR 2511871 A1 FR2511871 A1 FR 2511871A1 FR 8116478 A FR8116478 A FR 8116478A FR 8116478 A FR8116478 A FR 8116478A FR 2511871 A1 FR2511871 A1 FR 2511871A1
Authority
FR
France
Prior art keywords
compounds
acid
tribromo
product
benzene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8116478A
Other languages
English (en)
French (fr)
Other versions
FR2511871B1 (enExample
Inventor
Ioana Dimo
Bruno Bonnemain
Jean-Charles Hardouin
Jean-Francois Lautrou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guerbet SA
Original Assignee
Guerbet SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet SA filed Critical Guerbet SA
Priority to FR8116478A priority Critical patent/FR2511871A1/fr
Priority to US06/409,291 priority patent/US4474747A/en
Priority to ZA826033A priority patent/ZA826033B/xx
Priority to AU87474/82A priority patent/AU8747482A/en
Priority to EP82401580A priority patent/EP0074309A1/fr
Priority to DK383782A priority patent/DK383782A/da
Priority to FI822979A priority patent/FI822979L/fi
Priority to NO822908A priority patent/NO822908L/no
Priority to JP57149833A priority patent/JPS5874620A/ja
Publication of FR2511871A1 publication Critical patent/FR2511871A1/fr
Application granted granted Critical
Publication of FR2511871B1 publication Critical patent/FR2511871B1/fr
Granted legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/90—In vivo diagnostic or in vivo test agent which contains an additional ingredient to reduce the toxicity or side effects of the active ingredient

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Table Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR8116478A 1981-08-28 1981-08-28 Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus Granted FR2511871A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR8116478A FR2511871A1 (fr) 1981-08-28 1981-08-28 Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus
US06/409,291 US4474747A (en) 1981-08-28 1982-08-18 Process for increasing the tolerance of X-ray contrast media, and contrast media obtained thereby
ZA826033A ZA826033B (en) 1981-08-28 1982-08-19 Process for increasing the tolerance of x-ray contrast media,and contrast media obtained thereby
AU87474/82A AU8747482A (en) 1981-08-28 1982-08-20 X-ray contrast media comprising iodobenzene and bromo- benzene compounds
EP82401580A EP0074309A1 (fr) 1981-08-28 1982-08-25 Procédé pour augmenter la tolérance des produits opacifiants et produits opacifiants ainsi obtenus
DK383782A DK383782A (da) 1981-08-28 1982-08-27 Fremgangsmaade til foroegelse af tolerancen af roentgenstraalekontrastmedier og derved opnaaede kontrastmedier
FI822979A FI822979L (fi) 1981-08-28 1982-08-27 Foerfarande foer foerbaettring av toleransen av roentgenkontrastmedel och genom foerfarandet erhaolkontrastmedel
NO822908A NO822908L (no) 1981-08-28 1982-08-27 Roentgenkonstrastmidler.
JP57149833A JPS5874620A (ja) 1981-08-28 1982-08-28 Ｘ線造影剤の耐性を増加する方法、およびそれによつて得られる造影剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8116478A FR2511871A1 (fr) 1981-08-28 1981-08-28 Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus

Publications (2)

Publication Number Publication Date
FR2511871A1 true FR2511871A1 (fr) 1983-03-04
FR2511871B1 FR2511871B1 (enExample) 1983-12-23

Family

ID=9261753

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8116478A Granted FR2511871A1 (fr) 1981-08-28 1981-08-28 Procede pour augmenter la tolerance des produits opacifiants et produits opacifiants ainsi obtenus

Country Status (9)

Country Link
US (1) US4474747A (enExample)
EP (1) EP0074309A1 (enExample)
JP (1) JPS5874620A (enExample)
AU (1) AU8747482A (enExample)
DK (1) DK383782A (enExample)
FI (1) FI822979L (enExample)
FR (1) FR2511871A1 (enExample)
NO (1) NO822908L (enExample)
ZA (1) ZA826033B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204086A (en) * 1982-10-01 1993-04-20 Nycomed Imaging As X-ray contrast agent
JPS59104352A (ja) * 1982-11-08 1984-06-16 ニユエガ−ド・アンド・コンパニ−・アクシエ・セルカペト Ｘ線造影剤
JPH0625094B2 (ja) * 1988-03-01 1994-04-06 マリンクロット，インコーポレイテッド 非イオン性ｘ線コントラスト剤、組成物及び方法
US5043152A (en) * 1988-06-02 1991-08-27 Guerbet S.A. Novel iodinated non-ionic triiodobenzene compounds and contrast media containing them
US5143715A (en) * 1990-03-28 1992-09-01 Molecular Biosystems, Inc. Organic contrast agent analog and method of making same
US5250283A (en) * 1990-03-28 1993-10-05 Molecular Biosystems, Inc. Organic contrast agent analog and method of making same
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5622687A (en) * 1994-11-15 1997-04-22 Molecular Biosystems, Inc. Calixarene conjugates useful as MRI and CT diagnostic imaging agents
US5668196A (en) * 1995-08-10 1997-09-16 Nanosystems Llc 3-amido-triiodophenyl esters as x-ray contrast agents
US6751290B2 (en) 1998-09-08 2004-06-15 Veritas Pharmaceuticals, Inc. Radiographic assessment of tissue after exposure to a compound
US20010038682A1 (en) * 1998-09-08 2001-11-08 Jesse Salb Radiographic assessment of tissue response to compounds
US6723746B2 (en) 1998-09-08 2004-04-20 Veritas Pharmaceuticals, Inc. Functional radiographic imaging methods and agents
US6226352B1 (en) * 1998-09-08 2001-05-01 Veritas Pharmaceuticals, Inc. System and method for radiographic imaging of tissue
US6265610B1 (en) 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
ATE450201T1 (de) 2000-03-16 2009-12-15 Veritas Pharmaceuticals Radiographische bewertung von gewebereaktionen auf chemische verbindungen
EP1186305A1 (en) * 2000-09-07 2002-03-13 Schering Aktiengesellschaft New brominated compounds as contrast media for X-ray mammography
US7378081B2 (en) 2003-01-29 2008-05-27 Vincon Research Enterprises, Llc Composition and method for direct visualization of the human appendix
EP2253332B1 (en) * 2004-03-11 2012-10-10 Mallinckrodt LLC Low osmolar x-ray contrast media formulations
WO2006100731A1 (ja) * 2005-03-18 2006-09-28 Manac Inc. ５−アミノ−２，４，６−トリヨードイソフタル酸誘導体のアセチル化方法
MX2014001623A (es) 2011-08-10 2015-03-09 Digna Biotech Sl Uso de la cardiotofina-1 para el tratamiento de enfermedades renales.
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR820E (fr) * 1900-03-26 1903-04-02 Denayrouze Louis Briquette de chauffage à l'alcool et autres liquides volatils combustibles, à charge renouvelable
FR2162E (fr) * 1904-01-14 Andre Louis Veluard Dispositifs permettant la fabrication mécanique et continue du plumetis sur métiers à tisser de tous systèmes et pour tous genres de tissus
FR1088590A (fr) * 1952-08-16 1955-03-08 Schering Ag Agents de contraste pour rayons x et leur préparation
GB1033695A (en) * 1963-03-06 1966-06-22 Mallinckrodt Chemical Works Dibasic acid derivatives of 5-amino-n-alkyl-2,4,6-triiodoisophthalamic acids and preparation thereof
FR2074734A1 (en) * 1970-01-22 1971-10-08 Guerbet Lab Andre 3-(n-2-hydroxyethylcarbamyl)-5-(n-methylacetamido)2,4,6-triiodo- benz - acid - radiographic contrast agent
FR2085636A1 (enExample) * 1970-04-15 1971-12-31 Guerbet Lab Andre
FR2253509A1 (enExample) * 1973-12-07 1975-07-04 Guerbet Lab Andre
FR2272640A1 (enExample) * 1974-05-31 1975-12-26 Guerbet Lab Andre

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1870203A (en) * 1930-03-26 1932-08-02 Firm Schering Kahlbaum A G Compounds of the pyridine series
US2580459A (en) * 1946-11-27 1952-01-01 Schering Corp Production of halogenated aryl fatty acids
US2524827A (en) * 1948-05-13 1950-10-10 Schering Corp Halogen substituted polycyclic aryl aliphatic acids
NL74787C (enExample) * 1950-11-13
US2813118A (en) * 1953-07-16 1957-11-12 American Cystoscope Makers Inc X-ray contrast compounds
US3076024A (en) * 1954-02-19 1963-01-29 Sterling Drug Inc Acylated 3, 5-diaminopolyhalobenzoic acids
US2890244A (en) * 1956-09-07 1959-06-09 Endopharm Frankfurter Arzneimi 2, 4, 6-tribromo-3-acetylaminobenzoic acid and salts thereof
US3009952A (en) * 1957-04-17 1961-11-21 Sterling Drug Inc Preparation of halogenated isophthalic acids
BR6024559D0 (pt) * 1959-12-08 1973-05-31 Nyegaard & Co As Processo para preparacao de novos derivados de acido 3 5-diamino-2 4 6-triiodo benzoico ou semi sais nao toxicos bem como de agentes ou meios de contraste para raios x baseados nos mesmos
FR2162M (fr) * 1961-02-28 1963-11-25 Nyegaard & Co As Dérivés de n-alkylacylanilides, utiles, notamment comme agents de contraste pour rayons x.
US4073879A (en) * 1974-08-26 1978-02-14 University Of Illinois Foundation Brominated perfluorocarbon radiopaque agents

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2162E (fr) * 1904-01-14 Andre Louis Veluard Dispositifs permettant la fabrication mécanique et continue du plumetis sur métiers à tisser de tous systèmes et pour tous genres de tissus
FR820E (fr) * 1900-03-26 1903-04-02 Denayrouze Louis Briquette de chauffage à l'alcool et autres liquides volatils combustibles, à charge renouvelable
FR1088590A (fr) * 1952-08-16 1955-03-08 Schering Ag Agents de contraste pour rayons x et leur préparation
GB1033695A (en) * 1963-03-06 1966-06-22 Mallinckrodt Chemical Works Dibasic acid derivatives of 5-amino-n-alkyl-2,4,6-triiodoisophthalamic acids and preparation thereof
FR2074734A1 (en) * 1970-01-22 1971-10-08 Guerbet Lab Andre 3-(n-2-hydroxyethylcarbamyl)-5-(n-methylacetamido)2,4,6-triiodo- benz - acid - radiographic contrast agent
FR2085636A1 (enExample) * 1970-04-15 1971-12-31 Guerbet Lab Andre
FR2253509A1 (enExample) * 1973-12-07 1975-07-04 Guerbet Lab Andre
FR2272640A1 (enExample) * 1974-05-31 1975-12-26 Guerbet Lab Andre

Also Published As

Publication number Publication date
FI822979A7 (fi) 1983-03-01
JPS5874620A (ja) 1983-05-06
US4474747A (en) 1984-10-02
FR2511871B1 (enExample) 1983-12-23
AU8747482A (en) 1983-03-03
NO822908L (no) 1983-03-01
EP0074309A1 (fr) 1983-03-16
FI822979L (fi) 1983-03-01
ZA826033B (en) 1984-03-28
DK383782A (da) 1983-03-01
FI822979A0 (fi) 1982-08-27

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