JPS5827790B2 - 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類 - Google Patents

置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類

Info

Publication number
JPS5827790B2
JPS5827790B2 JP56100724A JP10072481A JPS5827790B2 JP S5827790 B2 JPS5827790 B2 JP S5827790B2 JP 56100724 A JP56100724 A JP 56100724A JP 10072481 A JP10072481 A JP 10072481A JP S5827790 B2 JPS5827790 B2 JP S5827790B2
Authority
JP
Japan
Prior art keywords
compound
formula
solution
mol
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56100724A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5745162A (en
Inventor
ボラ・ビタル・ジエツテイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pennwalt Corp
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR7204829A priority Critical patent/FR2171879A1/fr
Priority to DE2207430A priority patent/DE2207430C3/de
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Priority to JP56100724A priority patent/JPS5827790B2/ja
Publication of JPS5745162A publication Critical patent/JPS5745162A/ja
Publication of JPS5827790B2 publication Critical patent/JPS5827790B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP56100724A 1972-02-14 1981-06-30 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類 Expired JPS5827790B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7204829A FR2171879A1 (en) 1972-02-14 1972-02-14 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
DE2207430A DE2207430C3 (de) 1972-02-14 1972-02-14 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
JP56100724A JPS5827790B2 (ja) 1972-02-14 1981-06-30 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7204829A FR2171879A1 (en) 1972-02-14 1972-02-14 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
DE2207430A DE2207430C3 (de) 1972-02-14 1972-02-14 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
JP56100724A JPS5827790B2 (ja) 1972-02-14 1981-06-30 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類

Publications (2)

Publication Number Publication Date
JPS5745162A JPS5745162A (en) 1982-03-13
JPS5827790B2 true JPS5827790B2 (ja) 1983-06-11

Family

ID=27184114

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56100724A Expired JPS5827790B2 (ja) 1972-02-14 1981-06-30 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類

Country Status (3)

Country Link
JP (1) JPS5827790B2 ( )
DE (1) DE2207430C3 ( )
FR (1) FR2171879A1 ( )

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284556A (en) * 1980-01-31 1981-08-18 Smithkline Corporation 7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
KR20010113006A (ko) * 2000-06-15 2001-12-24 주정호 항암제로서 유용한 ｎ-치환된 벤즈아제피닐우레아 유도체및 그의 제조방법
JPWO2002074746A1 (ja) * 2001-03-16 2004-07-08 山之内製薬株式会社 ベンゾアゼピン誘導体
BR0317483A (pt) 2002-12-20 2005-11-16 Glaxo Group Ltd Derivados de benzodiazepina para o tratamento de desordens neurológicas
WO2007149728A2 (en) * 2006-06-20 2007-12-27 Alcon Research, Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1921861A1 (de) * 1968-04-29 1969-11-20 American Home Prod 3-Benzazepine,Verfahren zu ihrer Herstellung und ihre Verwendung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2520264A (en) * 1947-08-26 1950-08-29 Maltbie Lab Inc Substituted 3, 1-benz-2, 3, 4, 5-tetrahydroazepines
GB822506A (en) * 1956-11-29 1959-10-28 Ici Ltd 2:3:4:5-tetrahydrobenzazepinium salts
FR1473840A (fr) * 1965-04-02 1967-03-24 Alphachimie Nouveaux dérivés de la 2, 3, 4, 5-tétrahydro-(1h)-3-benzazépine et leurs procédés de fabrication
US3542760A (en) * 1966-04-25 1970-11-24 American Home Prod 7-alkoxy-2,3,4,5-tetrahydro-1h-1-benzazepine and derivatives thereof
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH498122A (de) * 1968-02-09 1970-10-31 Geigy Ag J R Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1921861A1 (de) * 1968-04-29 1969-11-20 American Home Prod 3-Benzazepine,Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
FR2171879B1 ( ) 1975-04-25
DE2207430A1 (de) 1973-08-23
DE2207430C3 (de) 1982-05-13
DE2207430B2 (de) 1981-07-23
JPS5745162A (en) 1982-03-13
FR2171879A1 (en) 1973-09-28

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