FR2171879A1 - 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc - Google Patents

1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc

Info

Publication number
FR2171879A1
FR2171879A1 FR7204829A FR7204829A FR2171879A1 FR 2171879 A1 FR2171879 A1 FR 2171879A1 FR 7204829 A FR7204829 A FR 7204829A FR 7204829 A FR7204829 A FR 7204829A FR 2171879 A1 FR2171879 A1 FR 2171879A1
Authority
FR
France
Prior art keywords
lower alkyl
alkyl
opt
phenyl
analgesics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7204829A
Other languages
English (en)
Other versions
FR2171879B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pennwalt Corp
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Priority to FR7204829A priority Critical patent/FR2171879A1/fr
Priority to DE2207430A priority patent/DE2207430C3/de
Publication of FR2171879A1 publication Critical patent/FR2171879A1/fr
Application granted granted Critical
Publication of FR2171879B1 publication Critical patent/FR2171879B1/fr
Priority to JP56100724A priority patent/JPS5827790B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FR7204829A 1972-02-14 1972-02-14 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc Granted FR2171879A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7204829A FR2171879A1 (en) 1972-02-14 1972-02-14 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
DE2207430A DE2207430C3 (de) 1972-02-14 1972-02-14 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
JP56100724A JPS5827790B2 (ja) 1972-02-14 1981-06-30 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7204829A FR2171879A1 (en) 1972-02-14 1972-02-14 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
DE2207430A DE2207430C3 (de) 1972-02-14 1972-02-14 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
JP56100724A JPS5827790B2 (ja) 1972-02-14 1981-06-30 置換１，２，４，５−テトラヒドロ−３ｈ，３−ベンゾアゼピン類

Publications (2)

Publication Number Publication Date
FR2171879A1 true FR2171879A1 (en) 1973-09-28
FR2171879B1 FR2171879B1 (fr) 1975-04-25

Family

ID=27184114

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7204829A Granted FR2171879A1 (en) 1972-02-14 1972-02-14 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc

Country Status (3)

Country Link
JP (1) JPS5827790B2 (fr)
DE (1) DE2207430C3 (fr)
FR (1) FR2171879A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007149728A2 (fr) * 2006-06-20 2007-12-27 Alcon Research, Ltd. Dérivés d'aryl et d'hétéroaryl tétrahydrobenzazépine et leur utilisation pour traiter le glaucome
EP2133340A1 (fr) 2002-12-20 2009-12-16 Glaxo Group Limited Nouveaux dérivés de benzazépine

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284556A (en) * 1980-01-31 1981-08-18 Smithkline Corporation 7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
KR20010113006A (ko) * 2000-06-15 2001-12-24 주정호 항암제로서 유용한 ｎ-치환된 벤즈아제피닐우레아 유도체및 그의 제조방법
JPWO2002074746A1 (ja) * 2001-03-16 2004-07-08 山之内製薬株式会社 ベンゾアゼピン誘導体

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1473840A (fr) * 1965-04-02 1967-03-24 Alphachimie Nouveaux dérivés de la 2, 3, 4, 5-tétrahydro-(1h)-3-benzazépine et leurs procédés de fabrication
FR1560654A (fr) * 1967-02-17 1969-03-21

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2520264A (en) * 1947-08-26 1950-08-29 Maltbie Lab Inc Substituted 3, 1-benz-2, 3, 4, 5-tetrahydroazepines
GB822506A (en) * 1956-11-29 1959-10-28 Ici Ltd 2:3:4:5-tetrahydrobenzazepinium salts
US3542760A (en) * 1966-04-25 1970-11-24 American Home Prod 7-alkoxy-2,3,4,5-tetrahydro-1h-1-benzazepine and derivatives thereof
CH498122A (de) * 1968-02-09 1970-10-31 Geigy Ag J R Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
GB1268943A (en) * 1968-04-29 1972-03-29 American Home Prod Benzazepines
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1473840A (fr) * 1965-04-02 1967-03-24 Alphachimie Nouveaux dérivés de la 2, 3, 4, 5-tétrahydro-(1h)-3-benzazépine et leurs procédés de fabrication
FR1560654A (fr) * 1967-02-17 1969-03-21

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2133340A1 (fr) 2002-12-20 2009-12-16 Glaxo Group Limited Nouveaux dérivés de benzazépine
US7696193B2 (en) 2002-12-20 2010-04-13 Glaxo Group Limited Benzazepine derivatives for the treatment of neurological disorders
US7704994B2 (en) 2002-12-20 2010-04-27 Glaxo Group Limited Benzazepine derivatives for the treatment of neurological disorders
EP2186516A1 (fr) 2002-12-20 2010-05-19 Glaxo Group Limited Nouveau dérivé de benzazépine
US7799773B2 (en) 2002-12-20 2010-09-21 Glaxo Group Limited Benzazepine derivatives for the treatment of neurological disorders
US8207331B2 (en) 2002-12-20 2012-06-26 Glaxo Group Limited Benzazepine derivatives for the treatment of neurological disorders
WO2007149728A2 (fr) * 2006-06-20 2007-12-27 Alcon Research, Ltd. Dérivés d'aryl et d'hétéroaryl tétrahydrobenzazépine et leur utilisation pour traiter le glaucome
WO2007149728A3 (fr) * 2006-06-20 2008-07-03 Alcon Res Ltd Dérivés d'aryl et d'hétéroaryl tétrahydrobenzazépine et leur utilisation pour traiter le glaucome

Also Published As

Publication number Publication date
FR2171879B1 (fr) 1975-04-25
DE2207430A1 (de) 1973-08-23
DE2207430C3 (de) 1982-05-13
JPS5827790B2 (ja) 1983-06-11
DE2207430B2 (de) 1981-07-23
JPS5745162A (en) 1982-03-13

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