JPS5823380B2 - ホルミルキノ ダツリホウ - Google Patents

ホルミルキノ ダツリホウ

Info

Publication number
JPS5823380B2
JPS5823380B2 JP49140646A JP14064674A JPS5823380B2 JP S5823380 B2 JPS5823380 B2 JP S5823380B2 JP 49140646 A JP49140646 A JP 49140646A JP 14064674 A JP14064674 A JP 14064674A JP S5823380 B2 JPS5823380 B2 JP S5823380B2
Authority
JP
Japan
Prior art keywords
formyl
ester
hydroxylamine
groups
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP49140646A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5168520A (en
Inventor
柿崎房義
竹本正
野田一郎
有吉安男
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP49140646A priority Critical patent/JPS5823380B2/ja
Priority to CA240,016A priority patent/CA1042875A/en
Priority to GB48458/75A priority patent/GB1496980A/en
Priority to US05/635,746 priority patent/US4021418A/en
Priority to DE2554421A priority patent/DE2554421C2/de
Priority to CH1578675A priority patent/CH599115A5/xx
Publication of JPS5168520A publication Critical patent/JPS5168520A/ja
Publication of JPS5823380B2 publication Critical patent/JPS5823380B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP49140646A 1974-12-05 1974-12-05 ホルミルキノ ダツリホウ Expired JPS5823380B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP49140646A JPS5823380B2 (ja) 1974-12-05 1974-12-05 ホルミルキノ ダツリホウ
CA240,016A CA1042875A (en) 1974-12-05 1975-11-19 Method of removing formyl groups from n-formyl-amino acid-n-formyl-peptide esters
GB48458/75A GB1496980A (en) 1974-12-05 1975-11-25 Process for removing formyl groups from n-formyl protected esters
US05/635,746 US4021418A (en) 1974-12-05 1975-11-26 Method of removing formyl groups from N-formyl-amino acid and N-formyl-peptide esters
DE2554421A DE2554421C2 (de) 1974-12-05 1975-12-03 Verfahren zur Abspaltung der Formylgruppe aus Estern von N-α-Formylaminosäuren oder N-α-Formylpeptiden mit primären oder sekundären Alkoholen
CH1578675A CH599115A5 (enExample) 1974-12-05 1975-12-04

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49140646A JPS5823380B2 (ja) 1974-12-05 1974-12-05 ホルミルキノ ダツリホウ

Publications (2)

Publication Number Publication Date
JPS5168520A JPS5168520A (en) 1976-06-14
JPS5823380B2 true JPS5823380B2 (ja) 1983-05-14

Family

ID=15273490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49140646A Expired JPS5823380B2 (ja) 1974-12-05 1974-12-05 ホルミルキノ ダツリホウ

Country Status (6)

Country Link
US (1) US4021418A (enExample)
JP (1) JPS5823380B2 (enExample)
CA (1) CA1042875A (enExample)
CH (1) CH599115A5 (enExample)
DE (1) DE2554421C2 (enExample)
GB (1) GB1496980A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61502983A (ja) * 1984-07-02 1986-12-18 バロ−ス・コ−ポレ−ション 表示端末装置の取付配置

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
IT1194795B (it) * 1981-05-13 1988-09-28 Pierrel Spa Procedimento per la eliminazione del gruppo n-formile da peptidi n-formilati e da esteri di peptidi n-formilati
JPH07636B2 (ja) * 1984-12-17 1995-01-11 三井東圧化学株式会社 Ｎ−ホルミル−α−アスパルチルフエニルアラニンの製造法
ES8703487A1 (es) * 1984-12-27 1987-03-01 Mitsui Toatsu Chemicals Procedimiento para la preparacion de a-l-aspartil-l-fenila- lanina metil ester
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
IT1190395B (it) * 1985-09-30 1988-02-16 Lark Spa Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido
US4730076A (en) * 1985-12-18 1988-03-08 Nippon Kayaku Kabushiki Kaisha Process for producing α-aspartyl-phenylalanine ester
DE3780585T2 (de) * 1986-12-05 1993-03-18 Mitsui Toatsu Chemicals Herstellung von alpha-l-aspartyl-l-phenylalanin-methylester oder deren hydrohalide.
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
US5017690A (en) * 1989-08-11 1991-05-21 W. R. Grace & Co.-Conn. Deblocking N-formyl aspartame compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1543610A1 (de) * 1966-08-27 1969-07-31 Hoechst Ag Verfahren zur Herstellung von Aminosaeuren und Peptiden und deren Derivaten

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61502983A (ja) * 1984-07-02 1986-12-18 バロ−ス・コ−ポレ−ション 表示端末装置の取付配置

Also Published As

Publication number Publication date
US4021418A (en) 1977-05-03
DE2554421A1 (de) 1976-06-10
DE2554421C2 (de) 1984-10-11
JPS5168520A (en) 1976-06-14
CH599115A5 (enExample) 1978-05-12
CA1042875A (en) 1978-11-21
GB1496980A (en) 1978-01-05

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