JPS58225091A - ペニシリン誘導体及びその製造法 - Google Patents

ペニシリン誘導体及びその製造法

Info

Publication number
JPS58225091A
JPS58225091A JP57107171A JP10717182A JPS58225091A JP S58225091 A JPS58225091 A JP S58225091A JP 57107171 A JP57107171 A JP 57107171A JP 10717182 A JP10717182 A JP 10717182A JP S58225091 A JPS58225091 A JP S58225091A
Authority
JP
Japan
Prior art keywords
general formula
group
reaction
acid
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57107171A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6124396B2 (enExample
Inventor
Jiyooji Miketeitsushiyu Ronarudo
ロナルド・ジヨ−ジ・ミケテイツシユ
Shigeru Yamabe
山辺　茂
Tomio Yamazaki
山崎　富生
Naofumi Ishida
石田　直文
Takeshi Ishizawa
石沢　武
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Priority to JP57107171A priority Critical patent/JPS58225091A/ja
Priority to AU15403/83A priority patent/AU541028B2/en
Priority to US06/501,560 priority patent/US4529592A/en
Priority to EP19830303268 priority patent/EP0097446B1/en
Priority to DE8383303268T priority patent/DE3362277D1/de
Priority to CA000429938A priority patent/CA1212939A/en
Priority to KR1019830002737A priority patent/KR900008677B1/ko
Priority to ES523701A priority patent/ES523701A0/es
Publication of JPS58225091A publication Critical patent/JPS58225091A/ja
Priority to ES538020A priority patent/ES8600765A1/es
Priority to CA000507098A priority patent/CA1222951A/en
Publication of JPS6124396B2 publication Critical patent/JPS6124396B2/ja
Priority to NL930140C priority patent/NL930140I2/nl
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57107171A 1982-06-21 1982-06-21 ペニシリン誘導体及びその製造法 Granted JPS58225091A (ja)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP57107171A JPS58225091A (ja) 1982-06-21 1982-06-21 ペニシリン誘導体及びその製造法
AU15403/83A AU541028B2 (en) 1982-06-21 1983-06-06 6-unsubstituted penicillin derivatives
US06/501,560 US4529592A (en) 1982-06-21 1983-06-06 Penicillin derivatives
EP19830303268 EP0097446B1 (en) 1982-06-21 1983-06-07 Penicillin derivatives and process for preparation of the same
DE8383303268T DE3362277D1 (en) 1982-06-21 1983-06-07 Penicillin derivatives and process for preparation of the same
CA000429938A CA1212939A (en) 1982-06-21 1983-06-08 Penicillin derivatives and process for preparation of the same
KR1019830002737A KR900008677B1 (ko) 1982-06-21 1983-06-18 페니실린 유도체의 제조방법
ES523701A ES523701A0 (es) 1982-06-21 1983-06-20 Procedimiento de preparar derivados de penicilina.
ES538020A ES8600765A1 (es) 1982-06-21 1984-11-27 Procedimiento de preparar derivados de penicilina
CA000507098A CA1222951A (en) 1982-06-21 1986-04-18 Pencillin derivatives and process for preparation of the same
NL930140C NL930140I2 (nl) 1982-06-21 1993-09-23 Penicillinederivaten en werkwijze voor de bereiding daarvan.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57107171A JPS58225091A (ja) 1982-06-21 1982-06-21 ペニシリン誘導体及びその製造法

Publications (2)

Publication Number Publication Date
JPS58225091A true JPS58225091A (ja) 1983-12-27
JPS6124396B2 JPS6124396B2 (enExample) 1986-06-10

Family

ID=14452274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57107171A Granted JPS58225091A (ja) 1982-06-21 1982-06-21 ペニシリン誘導体及びその製造法

Country Status (4)

Country Link
US (1) US4529592A (enExample)
JP (1) JPS58225091A (enExample)
KR (1) KR900008677B1 (enExample)
CA (1) CA1212939A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61126087A (ja) * 1984-11-26 1986-06-13 Taiho Yakuhin Kogyo Kk ２α−メチル−２β−（１，２，３−トリアゾ−ル−１−イル）メチルペナム−３α−カルボン酸誘導体の製造法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof
JP2602685B2 (ja) * 1988-03-01 1997-04-23 大鵬薬品工業株式会社 ２α−メチル−２β―（１，２，３−トリアゾール−１−イル）メチルペナム−３α−カルボン酸誘導体の製造法
JP2599610B2 (ja) * 1988-03-01 1997-04-09 大鵬薬品工業株式会社 ２β―置換メチルペニシリン誘導体の製造法
US4958020A (en) * 1989-05-12 1990-09-18 American Cyanamid Company Process for producing β-lactamase inhibitor
KR100431052B1 (ko) * 2001-10-08 2004-05-12 주식회사 네오텍리서치 표면 굴곡에 의하여 형성된 다중 영역 효과를 가지는 액정표시 장치
BR0215776A (pt) * 2002-06-07 2005-03-01 Orchid Chemicals & Pharm Ltd Processo para a preparação de derivados de pename a partir de derivados de cefame
US20060173177A1 (en) 2005-01-28 2006-08-03 Gego Csaba L Process for preparation of penam derivatives
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
PL2893929T3 (pl) 2013-03-15 2025-07-21 Merck Sharp & Dohme Llc Kompozycje antybiotykowe ceftolozanu
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
EP3043797B1 (en) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT365594B (de) * 1978-11-24 1982-01-25 Erba Farmitalia Verfahren zur herstellung von neuen 7-oxo-4-thia1-aza-bicyclo-(3,2,0)heptanderivaten

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61126087A (ja) * 1984-11-26 1986-06-13 Taiho Yakuhin Kogyo Kk ２α−メチル−２β−（１，２，３−トリアゾ−ル−１−イル）メチルペナム−３α−カルボン酸誘導体の製造法

Also Published As

Publication number Publication date
KR840005148A (ko) 1984-11-03
US4529592A (en) 1985-07-16
CA1212939A (en) 1986-10-21
KR900008677B1 (ko) 1990-11-26
JPS6124396B2 (enExample) 1986-06-10

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