JPS5731930A - Production of cytotoxic substance-bound reactive polymer - Google Patents
Production of cytotoxic substance-bound reactive polymerInfo
- Publication number
- JPS5731930A JPS5731930A JP10637680A JP10637680A JPS5731930A JP S5731930 A JPS5731930 A JP S5731930A JP 10637680 A JP10637680 A JP 10637680A JP 10637680 A JP10637680 A JP 10637680A JP S5731930 A JPS5731930 A JP S5731930A
- Authority
- JP
- Japan
- Prior art keywords
- reactive polymer
- cytotoxic substance
- amino
- group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 231100000433 cytotoxic Toxicity 0.000 title abstract 4
- 230000001472 cytotoxic effect Effects 0.000 title abstract 4
- 229920013730 reactive polymer Polymers 0.000 title abstract 4
- 239000000126 substance Substances 0.000 title abstract 4
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical compound C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 238000006116 polymerization reaction Methods 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000002228 disulfide group Chemical group 0.000 abstract 1
- 229960004857 mitomycin Drugs 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polyamides (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10637680A JPS5731930A (en) | 1980-08-04 | 1980-08-04 | Production of cytotoxic substance-bound reactive polymer |
| DE8181302118T DE3175151D1 (en) | 1980-05-21 | 1981-05-13 | Reactive polymer and process for the preparation thereof |
| EP81302118A EP0040506B1 (en) | 1980-05-21 | 1981-05-13 | Reactive polymer and process for the preparation thereof |
| US06/265,924 US4385169A (en) | 1980-05-21 | 1981-05-21 | Reactive alpha amino acid polymer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10637680A JPS5731930A (en) | 1980-08-04 | 1980-08-04 | Production of cytotoxic substance-bound reactive polymer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5731930A true JPS5731930A (en) | 1982-02-20 |
| JPS6219770B2 JPS6219770B2 (enrdf_load_stackoverflow) | 1987-05-01 |
Family
ID=14431989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10637680A Granted JPS5731930A (en) | 1980-05-21 | 1980-08-04 | Production of cytotoxic substance-bound reactive polymer |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5731930A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59116232A (ja) * | 1982-12-24 | 1984-07-05 | Teijin Ltd | 細胞毒性複合体及びその製造法 |
| JPS59159827A (ja) * | 1983-03-02 | 1984-09-10 | Teijin Ltd | 細胞毒性物質を結合した反応性重合体の製造法 |
| JPS62275128A (ja) * | 1986-02-14 | 1987-11-30 | Nippon Mejifuijitsukusu Kk | アミノ基と２官能性配位子を有する反応性高分子化合物とその利用 |
| JPS63302909A (ja) * | 1987-06-01 | 1988-12-09 | Kurita Mach Mfg Co Ltd | フイルタプレス |
-
1980
- 1980-08-04 JP JP10637680A patent/JPS5731930A/ja active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59116232A (ja) * | 1982-12-24 | 1984-07-05 | Teijin Ltd | 細胞毒性複合体及びその製造法 |
| JPS59159827A (ja) * | 1983-03-02 | 1984-09-10 | Teijin Ltd | 細胞毒性物質を結合した反応性重合体の製造法 |
| JPS62275128A (ja) * | 1986-02-14 | 1987-11-30 | Nippon Mejifuijitsukusu Kk | アミノ基と２官能性配位子を有する反応性高分子化合物とその利用 |
| JPS63302909A (ja) * | 1987-06-01 | 1988-12-09 | Kurita Mach Mfg Co Ltd | フイルタプレス |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6219770B2 (enrdf_load_stackoverflow) | 1987-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5429400A (en) | Polymer comprising polyalkylpiperidine and its use as stabilizers | |
| JPS5731930A (en) | Production of cytotoxic substance-bound reactive polymer | |
| JPS51146466A (en) | A process for preparing 1,3-dithiolan-2- iridenmalonate derivatives an d their use | |
| JPS5747304A (en) | Novel tris bipyridyl ruthenium high polymeric complex and its preparation | |
| JPS57183768A (en) | 4-methyl-5-(o-carboxyphenyl)carbamoylthiazole derivative and its preparation | |
| IL42590A (en) | 3-alkyl-4-sulphamoyl-aniline derivatives and processes for the preparation thereof | |
| JPS5655438A (en) | Stabilized polymer composition | |
| GB1255588A (en) | Aromatic linear copolythioethers | |
| IE41471L (en) | Preparing moulded articles or coatings | |
| JPS5742717A (en) | Polycarbonate-urea and its production | |
| JPS5688422A (en) | Poly (n-alkyl-3,6-carbazolediyl) and production thereof | |
| JPS5731918A (en) | Production of polyacetal polymer | |
| IE40728B1 (en) | 2,3,8,12b-tetrahydro-1h-3a,8-methanodibenzo(3,4:6,7)cyclohepta-(1,2-c)pyrrole and derivatives thereof | |
| JPS5464600A (en) | Preparation of polyaluminoxane chelate compound | |
| JPS5455522A (en) | Acylated 2-3-(2-chloroethyl)ureido-2- deoxyglucopyranosides derivatives | |
| JPS5721400A (en) | Novel fortimicin derivative | |
| JPS5473758A (en) | Asymmetric synthesis of chrysanthemumic acid derivative ester | |
| JPS57102957A (en) | Dye-dissolving aid | |
| JPS54106481A (en) | Novel 2,3-dioxopiperazine derivative and its preparation | |
| CA2022607A1 (en) | Additive for production of paper | |
| JPS5632472A (en) | Preparation of chemotherapeutically useful salicylic acid double salt | |
| GB1278517A (en) | Thermostable heterocyclic polymers consisting of poly 2-quinoxalinones and similar cyclic compounds and their process of manufacture | |
| JPS57126823A (en) | Silyl-terminated polymer and its production | |
| JPS5616465A (en) | Novel polydithiocarbamate, its preparation and agricultural and industrial chemical containing the same | |
| JPS56108777A (en) | Novel guanidinothiazole derivative and its preparation |