JPS5731615A - Remedy for skin disease with keratinization - Google Patents

Remedy for skin disease with keratinization

Info

Publication number
JPS5731615A
JPS5731615A JP10442080A JP10442080A JPS5731615A JP S5731615 A JPS5731615 A JP S5731615A JP 10442080 A JP10442080 A JP 10442080A JP 10442080 A JP10442080 A JP 10442080A JP S5731615 A JPS5731615 A JP S5731615A
Authority
JP
Japan
Prior art keywords
keratinization
remedy
skin disease
hexadecapentaenic
tetramethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10442080A
Other languages
English (en)
Other versions
JPH0131484B2 (ja
Inventor
Takumi Yamatsu
Yuichi Inai
Shinya Abe
Takeshi Suzuki
Yoshikazu Suzuki
Osamu Tagaya
Nozomi Koyanagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP10442080A priority Critical patent/JPS5731615A/ja
Priority to US06/249,290 priority patent/US4346109A/en
Priority to GB8110160A priority patent/GB2073750B/en
Priority to NL8101630A priority patent/NL191744C/xx
Priority to DE19813113149 priority patent/DE3113149A1/de
Priority to PH25463A priority patent/PH15861A/en
Priority to SE8102161A priority patent/SE447243B/sv
Priority to CH231781A priority patent/CH646682A5/fr
Priority to FR8106874A priority patent/FR2479807A1/fr
Priority to ES501124A priority patent/ES8205190A1/es
Priority to DK155081A priority patent/DK158457C/da
Priority to CA000374715A priority patent/CA1179370A/en
Priority to AU69159/81A priority patent/AU537402B2/en
Priority to KR1019810001169A priority patent/KR840001518B1/ko
Priority to IT20967/81A priority patent/IT1194141B/it
Publication of JPS5731615A publication Critical patent/JPS5731615A/ja
Priority to ES509913A priority patent/ES8304058A1/es
Priority to KR1019830005299A priority patent/KR850000019B1/ko
Publication of JPH0131484B2 publication Critical patent/JPH0131484B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
JP10442080A 1980-04-07 1980-07-31 Remedy for skin disease with keratinization Granted JPS5731615A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
JP10442080A JPS5731615A (en) 1980-07-31 1980-07-31 Remedy for skin disease with keratinization
US06/249,290 US4346109A (en) 1980-07-31 1981-03-30 Method of treating keratotic skin disease
GB8110160A GB2073750B (en) 1980-04-07 1981-04-01 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
NL8101630A NL191744C (nl) 1980-04-07 1981-04-01 Farmaceutisch preparaat met werking tegen epitheelletsels.
DE19813113149 DE3113149A1 (de) 1980-04-07 1981-04-01 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaensaeure, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und ihre verwendung als antikrebsmittel und therapeutisches mittel fuer die behandlung von hauterkrankungen
PH25463A PH15861A (en) 1980-07-31 1981-04-02 Method of treating skin disease with keratinization
SE8102161A SE447243B (sv) 1980-04-07 1981-04-03 3,7,11,15-tetrametyl-2,4,6,10,14-hexadekapentaensyra samt farmaceutisk komposition innehallande denna
ES501124A ES8205190A1 (es) 1980-04-07 1981-04-06 Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10-14-hexadecapentaenoico.
FR8106874A FR2479807A1 (fr) 1980-04-07 1981-04-06 Acide 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoique, procedes pour sa preparation et composition therapeutique le contenant
CH231781A CH646682A5 (fr) 1980-04-07 1981-04-06 Acide tetramethyl-hexadecapentaenoique, procedes pour sa preparation et composition pharmaceutique contenant cet acide.
DK155081A DK158457C (da) 1980-04-07 1981-04-06 Analogifremgangsmaade til fremstilling af 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaensyre eller salte heraf
CA000374715A CA1179370A (en) 1980-04-07 1981-04-06 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
AU69159/81A AU537402B2 (en) 1980-04-07 1981-04-07 3,7,11,15-tetra methyl-2-4,6,10,14-hexadecapenta enoic acid
KR1019810001169A KR840001518B1 (ko) 1980-07-31 1981-04-07 3,7,11,15-테트라메틸-2,4,6,10,14-헥사데카펜타엔산(酸)의 제조방법
IT20967/81A IT1194141B (it) 1980-04-07 1981-04-07 Acido 3, 7, 11, 15-tetrametil-2, 4, 6, 10, 14-esadecapentaenoico
ES509913A ES8304058A1 (es) 1980-04-07 1982-02-25 Un procedimiento para la preparacion del acido 3,7,11,15-tetrametil-2,4,6,10,14-hexadecapentaenoico.
KR1019830005299A KR850000019B1 (ko) 1980-07-31 1983-11-08 3,7,11,15-테트라메틸-2,4,6,10,14-헥사데카펜타엔산(酸)의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10442080A JPS5731615A (en) 1980-07-31 1980-07-31 Remedy for skin disease with keratinization

Publications (2)

Publication Number Publication Date
JPS5731615A true JPS5731615A (en) 1982-02-20
JPH0131484B2 JPH0131484B2 (ja) 1989-06-26

Family

ID=14380194

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10442080A Granted JPS5731615A (en) 1980-04-07 1980-07-31 Remedy for skin disease with keratinization

Country Status (4)

Country Link
US (1) US4346109A (ja)
JP (1) JPS5731615A (ja)
KR (2) KR840001518B1 (ja)
PH (1) PH15861A (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468458A (en) * 1980-01-12 1984-08-28 Eisai Co., Ltd. Two-functional-group-containing terpenoids, processes for the preparation of the same, and anti-ulcer agents containing the same
JPS56140949A (en) * 1980-04-07 1981-11-04 Eisai Co Ltd 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
JPS57106618A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Anticancer agent consisting of polyprenyl compound
JPS5815940A (ja) * 1981-07-23 1983-01-29 Eisai Co Ltd ポリプレニル系化合物およびその製造方法ならびにそれを含有する医薬
JPS5973516A (ja) * 1982-10-21 1984-04-25 Eisai Co Ltd 抗炎症剤
JPS59101448A (ja) * 1982-11-30 1984-06-12 Eisai Co Ltd ポリプレニルカルボン酸アミドおよびその製造方法ならびにそれを含有する医薬
FR2563431B1 (fr) * 1984-04-26 1987-03-06 Roussel Uclaf Nouvelles compositions cosmetiques renfermant des extraits lyses d'hafnia
GB2216003B (en) * 1988-02-18 1992-06-10 Toyama Chemical Co Ltd Hair restorer
US5175190A (en) * 1991-02-15 1992-12-29 The University Of British Columbia Medium chain fatty acids of C8-10 for the treatment of skin lesions
US20050250671A1 (en) * 2000-04-24 2005-11-10 Yoshihiro Shidoji Activators of peroxisome proliferator-activated receptor
KR20100041891A (ko) * 2002-05-17 2010-04-22 코와소야쿠 가부시키가이샤 간염세포 및/또는 간경변 세포의 형질전환을 억제하는 간암 예방제
EP1547588B1 (en) * 2002-08-20 2013-12-11 Kowa Company, Ltd. Soft capsule preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966967A (en) * 1973-03-21 1976-06-29 The Regents Of The University Of California Compositions and methods of treating psoriasis with vinyligs of desmethyl retinoic acid
US3934028A (en) * 1974-04-22 1976-01-20 The Regents Of The University Of California Acne and psoriasis treatment with retinoic acid analogs
JPS5257107A (en) * 1975-10-30 1977-05-11 Hoffmann La Roche Polyene compound and method of producing same
JPS52144614A (en) * 1976-05-27 1977-12-02 Eisai Co Ltd Polyprenyl carboxylic acid compounds and hypo-tensor containing same

Also Published As

Publication number Publication date
KR840004667A (ko) 1984-10-22
PH15861A (en) 1983-04-13
KR850000019B1 (ko) 1985-02-11
US4346109A (en) 1982-08-24
JPH0131484B2 (ja) 1989-06-26
KR840001518B1 (ko) 1984-09-29
KR830005090A (ko) 1983-07-23

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