JPS54122220A - Preparation of high purity isoprenyl acetic acid - Google Patents
Preparation of high purity isoprenyl acetic acidInfo
- Publication number
- JPS54122220A JPS54122220A JP2778978A JP2778978A JPS54122220A JP S54122220 A JPS54122220 A JP S54122220A JP 2778978 A JP2778978 A JP 2778978A JP 2778978 A JP2778978 A JP 2778978A JP S54122220 A JPS54122220 A JP S54122220A
- Authority
- JP
- Japan
- Prior art keywords
- isoprenyl
- acetic acid
- formula
- compound containing
- high purity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To obtain a high purity isoprenyl acetic acid useful as a synthetic intermediate of isoprenyl acetic acid ester which is an antiulcerative, in high yield without side reactions, by the decarboxylation of isoprenyl malonic acid in the presence of a compound containing a basic metal.
CONSTITUTION: Isoprenyl acetic acid of formula II is obtained by the thermal decarboxylation of isoprenyl malonic acid of formula I (R is sioprenyl which means terpenehydrocarbon residue, e.g. formula III, formula IV, etc.) at 90W150°C in the presence of a compound containing a basic metal (preferably alkali metal alcoholate). The compound containing a basic metal is used in an amount of 0.001W0.5 times mol, preferably 0.003W0.05 times mol, based on the starting material. The compound of formula I is obtained by brominating isoprenyl alcohol, condensing the product with a sodium salt of dialkyl malonate, and hydrolyzing the condensate.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2778978A JPS54122220A (en) | 1978-03-13 | 1978-03-13 | Preparation of high purity isoprenyl acetic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2778978A JPS54122220A (en) | 1978-03-13 | 1978-03-13 | Preparation of high purity isoprenyl acetic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54122220A true JPS54122220A (en) | 1979-09-21 |
JPS6139933B2 JPS6139933B2 (en) | 1986-09-06 |
Family
ID=12230729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2778978A Granted JPS54122220A (en) | 1978-03-13 | 1978-03-13 | Preparation of high purity isoprenyl acetic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54122220A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57120546A (en) * | 1980-11-29 | 1982-07-27 | Dynamit Nobel Ag | Manufacture of substituted acetic acid and/or its ester or substituted acetonitrile |
WO2005028410A1 (en) * | 2003-09-19 | 2005-03-31 | Ube Industries, Ltd. | Method for producing nitrile compound, carboxylic acid compound or carboxylate compound |
JP2007119352A (en) * | 2005-10-25 | 2007-05-17 | Ube Ind Ltd | Method for producing 2-aryl- or heteroarylacetic acid compound |
CN100432038C (en) * | 2003-09-19 | 2008-11-12 | 宇部兴产株式会社 | Method for producing nitrile compound, carboxylic acid compound or carboxylate compound |
-
1978
- 1978-03-13 JP JP2778978A patent/JPS54122220A/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57120546A (en) * | 1980-11-29 | 1982-07-27 | Dynamit Nobel Ag | Manufacture of substituted acetic acid and/or its ester or substituted acetonitrile |
JPH0261445B2 (en) * | 1980-11-29 | 1990-12-20 | Dynamit Nobel Ag | |
WO2005028410A1 (en) * | 2003-09-19 | 2005-03-31 | Ube Industries, Ltd. | Method for producing nitrile compound, carboxylic acid compound or carboxylate compound |
US7300953B2 (en) | 2003-09-19 | 2007-11-27 | Ube Industries, Ltd | Process for preparing nitrile compound, carboxylic acid compound or carboxylic acid ester compound |
CN100432038C (en) * | 2003-09-19 | 2008-11-12 | 宇部兴产株式会社 | Method for producing nitrile compound, carboxylic acid compound or carboxylate compound |
JP2007119352A (en) * | 2005-10-25 | 2007-05-17 | Ube Ind Ltd | Method for producing 2-aryl- or heteroarylacetic acid compound |
Also Published As
Publication number | Publication date |
---|---|
JPS6139933B2 (en) | 1986-09-06 |
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