JPS5524117A - Preparation of 2-(3-benzoylphenyl) propionic acid - Google Patents

Preparation of 2-(3-benzoylphenyl) propionic acid

Info

Publication number
JPS5524117A
JPS5524117A JP9646378A JP9646378A JPS5524117A JP S5524117 A JPS5524117 A JP S5524117A JP 9646378 A JP9646378 A JP 9646378A JP 9646378 A JP9646378 A JP 9646378A JP S5524117 A JPS5524117 A JP S5524117A
Authority
JP
Japan
Prior art keywords
benzoylphenyl
novel
dialkyl ester
formula
methylmalonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9646378A
Other languages
Japanese (ja)
Inventor
Takeo Soga
Hirosuke Hane
Mitsuo Iwamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIKKEN KAGAKU KK
Nikken Chemicals Co Ltd
Original Assignee
NIKKEN KAGAKU KK
Nikken Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIKKEN KAGAKU KK, Nikken Chemicals Co Ltd filed Critical NIKKEN KAGAKU KK
Priority to JP9646378A priority Critical patent/JPS5524117A/en
Publication of JPS5524117A publication Critical patent/JPS5524117A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the title compound for analgesics and antiphlogistics in high yield, by hydrolyzing and decarboxylating a novel intermediate 2-(3-benzoyl phenyl) -2-methylmalonic dialkyl ester, prepared from a novel material through methylation.
CONSTITUTION: A 2-(3-benzoylphenyl)-2-methylmalonic dialkyl ester of formula I: (R is alkyl group) is hydrolyzed and decarboxlated to give a 2-(3-benzoylphenyl) propionic acid of formula II. The novel 2-(3-benzoylphenyl)-2- methylmalonic dialkyl ester of formula I can be obtained by methylating the novel 2- (3-benzoylphenyl) malonic dialkyl ester. The raw material of the compound of formula III is obtained by reacting 2-(3-benzoylphenyl)-2-carboalkoxyacetonitrile with an alcohol and water in the presence of an acid catalyst.
COPYRIGHT: (C)1980,JPO&Japio
JP9646378A 1978-08-08 1978-08-08 Preparation of 2-(3-benzoylphenyl) propionic acid Pending JPS5524117A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9646378A JPS5524117A (en) 1978-08-08 1978-08-08 Preparation of 2-(3-benzoylphenyl) propionic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9646378A JPS5524117A (en) 1978-08-08 1978-08-08 Preparation of 2-(3-benzoylphenyl) propionic acid

Publications (1)

Publication Number Publication Date
JPS5524117A true JPS5524117A (en) 1980-02-21

Family

ID=14165713

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9646378A Pending JPS5524117A (en) 1978-08-08 1978-08-08 Preparation of 2-(3-benzoylphenyl) propionic acid

Country Status (1)

Country Link
JP (1) JPS5524117A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5734145A (en) * 1980-08-07 1982-02-24 Mitsui Petrochem Ind Ltd Ethylene-alpha-olefin copolymer composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5734145A (en) * 1980-08-07 1982-02-24 Mitsui Petrochem Ind Ltd Ethylene-alpha-olefin copolymer composition
JPS6210532B2 (en) * 1980-08-07 1987-03-06 Mitsui Petrochemical Ind

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