JPS5524117A - Preparation of 2-(3-benzoylphenyl) propionic acid - Google Patents
Preparation of 2-(3-benzoylphenyl) propionic acidInfo
- Publication number
- JPS5524117A JPS5524117A JP9646378A JP9646378A JPS5524117A JP S5524117 A JPS5524117 A JP S5524117A JP 9646378 A JP9646378 A JP 9646378A JP 9646378 A JP9646378 A JP 9646378A JP S5524117 A JPS5524117 A JP S5524117A
- Authority
- JP
- Japan
- Prior art keywords
- benzoylphenyl
- novel
- dialkyl ester
- formula
- methylmalonic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To obtain the title compound for analgesics and antiphlogistics in high yield, by hydrolyzing and decarboxylating a novel intermediate 2-(3-benzoyl phenyl) -2-methylmalonic dialkyl ester, prepared from a novel material through methylation.
CONSTITUTION: A 2-(3-benzoylphenyl)-2-methylmalonic dialkyl ester of formula I: (R is alkyl group) is hydrolyzed and decarboxlated to give a 2-(3-benzoylphenyl) propionic acid of formula II. The novel 2-(3-benzoylphenyl)-2- methylmalonic dialkyl ester of formula I can be obtained by methylating the novel 2- (3-benzoylphenyl) malonic dialkyl ester. The raw material of the compound of formula III is obtained by reacting 2-(3-benzoylphenyl)-2-carboalkoxyacetonitrile with an alcohol and water in the presence of an acid catalyst.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9646378A JPS5524117A (en) | 1978-08-08 | 1978-08-08 | Preparation of 2-(3-benzoylphenyl) propionic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9646378A JPS5524117A (en) | 1978-08-08 | 1978-08-08 | Preparation of 2-(3-benzoylphenyl) propionic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5524117A true JPS5524117A (en) | 1980-02-21 |
Family
ID=14165713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9646378A Pending JPS5524117A (en) | 1978-08-08 | 1978-08-08 | Preparation of 2-(3-benzoylphenyl) propionic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5524117A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5734145A (en) * | 1980-08-07 | 1982-02-24 | Mitsui Petrochem Ind Ltd | Ethylene-alpha-olefin copolymer composition |
-
1978
- 1978-08-08 JP JP9646378A patent/JPS5524117A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5734145A (en) * | 1980-08-07 | 1982-02-24 | Mitsui Petrochem Ind Ltd | Ethylene-alpha-olefin copolymer composition |
JPS6210532B2 (en) * | 1980-08-07 | 1987-03-06 | Mitsui Petrochemical Ind |
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