JPS5762275A - Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid - Google Patents

Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid

Info

Publication number
JPS5762275A
JPS5762275A JP13709580A JP13709580A JPS5762275A JP S5762275 A JPS5762275 A JP S5762275A JP 13709580 A JP13709580 A JP 13709580A JP 13709580 A JP13709580 A JP 13709580A JP S5762275 A JPS5762275 A JP S5762275A
Authority
JP
Japan
Prior art keywords
thenoyl
compound
phenyl
preparation
propionic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13709580A
Other languages
Japanese (ja)
Inventor
Makoto Takeda
Eiji Taniyama
Hiroshi Iwane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Petrochemical Co Ltd
Original Assignee
Mitsubishi Petrochemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Petrochemical Co Ltd filed Critical Mitsubishi Petrochemical Co Ltd
Priority to JP13709580A priority Critical patent/JPS5762275A/en
Publication of JPS5762275A publication Critical patent/JPS5762275A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound useful as an analgesic and anti-inflammatory agent in an easy operation industrially and advantageously, by reacting an easily preparable novel p-(2-thenoyl)styrene as a raw material with carbon monoxide in the presence of water.
CONSTITUTION: A p-(2-thenoyl)styrene of formulaI(X is H, halogen or 1W4C lower alkyl) as a raw material is reacted with carbon monoxide in the presence of water or in the presence of an alcohol of the formula R-OH (R is 1W6C alkyl or 7W9C aralkyl) to give a compound of formula II. The compound of formulaIis a novel compound and obtained by reacting a Grignard reagent obtained from a p- halostyrene and magnesium with a 2-cyanothiophene, and hydrolyzing the resultant reaction product.
COPYRIGHT: (C)1982,JPO&Japio
JP13709580A 1980-10-01 1980-10-01 Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid Pending JPS5762275A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13709580A JPS5762275A (en) 1980-10-01 1980-10-01 Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13709580A JPS5762275A (en) 1980-10-01 1980-10-01 Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid

Publications (1)

Publication Number Publication Date
JPS5762275A true JPS5762275A (en) 1982-04-15

Family

ID=15190748

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13709580A Pending JPS5762275A (en) 1980-10-01 1980-10-01 Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid

Country Status (1)

Country Link
JP (1) JPS5762275A (en)

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