JPS5762275A - Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid - Google Patents
Preparation of 2-(p-(2-thenoyl)phenyl)propionic acidInfo
- Publication number
- JPS5762275A JPS5762275A JP13709580A JP13709580A JPS5762275A JP S5762275 A JPS5762275 A JP S5762275A JP 13709580 A JP13709580 A JP 13709580A JP 13709580 A JP13709580 A JP 13709580A JP S5762275 A JPS5762275 A JP S5762275A
- Authority
- JP
- Japan
- Prior art keywords
- thenoyl
- compound
- phenyl
- preparation
- propionic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To obtain the titled compound useful as an analgesic and anti-inflammatory agent in an easy operation industrially and advantageously, by reacting an easily preparable novel p-(2-thenoyl)styrene as a raw material with carbon monoxide in the presence of water.
CONSTITUTION: A p-(2-thenoyl)styrene of formulaI(X is H, halogen or 1W4C lower alkyl) as a raw material is reacted with carbon monoxide in the presence of water or in the presence of an alcohol of the formula R-OH (R is 1W6C alkyl or 7W9C aralkyl) to give a compound of formula II. The compound of formulaIis a novel compound and obtained by reacting a Grignard reagent obtained from a p- halostyrene and magnesium with a 2-cyanothiophene, and hydrolyzing the resultant reaction product.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13709580A JPS5762275A (en) | 1980-10-01 | 1980-10-01 | Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13709580A JPS5762275A (en) | 1980-10-01 | 1980-10-01 | Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5762275A true JPS5762275A (en) | 1982-04-15 |
Family
ID=15190748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13709580A Pending JPS5762275A (en) | 1980-10-01 | 1980-10-01 | Preparation of 2-(p-(2-thenoyl)phenyl)propionic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5762275A (en) |
-
1980
- 1980-10-01 JP JP13709580A patent/JPS5762275A/en active Pending
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