JPS5785338A - Fluoromalonic acid derivative and its production - Google Patents

Fluoromalonic acid derivative and its production

Info

Publication number
JPS5785338A
JPS5785338A JP16018280A JP16018280A JPS5785338A JP S5785338 A JPS5785338 A JP S5785338A JP 16018280 A JP16018280 A JP 16018280A JP 16018280 A JP16018280 A JP 16018280A JP S5785338 A JPS5785338 A JP S5785338A
Authority
JP
Japan
Prior art keywords
production
acid derivative
fluoro
formula
fluoromalonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16018280A
Other languages
Japanese (ja)
Other versions
JPS6034940B2 (en
Inventor
Nobuo Ishikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daikin Industries Ltd
Original Assignee
Daikin Industries Ltd
Daikin Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daikin Industries Ltd, Daikin Kogyo Co Ltd filed Critical Daikin Industries Ltd
Priority to JP16018280A priority Critical patent/JPS6034940B2/en
Publication of JPS5785338A publication Critical patent/JPS5785338A/en
Publication of JPS6034940B2 publication Critical patent/JPS6034940B2/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:2-Fluoro-2-substituted malonic dialkyl ester of formula I (R, R' are lower alkyl; R" is 1W10C hydrocarbon group).
EXAMPLE: Dimethyl 2-fluoro-2-methylmalonate.
USE: Synthetic intermediate of a physiologically active substance such as hypnotic.
PREPARATION: The reaction of dialkyl 2-fluoromalonate of formula II with a halide of R"X(X is halogen) is effected in the presence of an alkali metal alkoxide, preferably in a solvent such as alcohol.
COPYRIGHT: (C)1982,JPO&Japio
JP16018280A 1980-11-13 1980-11-13 Fluoromalonic acid derivatives and their production method Expired JPS6034940B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16018280A JPS6034940B2 (en) 1980-11-13 1980-11-13 Fluoromalonic acid derivatives and their production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16018280A JPS6034940B2 (en) 1980-11-13 1980-11-13 Fluoromalonic acid derivatives and their production method

Publications (2)

Publication Number Publication Date
JPS5785338A true JPS5785338A (en) 1982-05-28
JPS6034940B2 JPS6034940B2 (en) 1985-08-12

Family

ID=15709596

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16018280A Expired JPS6034940B2 (en) 1980-11-13 1980-11-13 Fluoromalonic acid derivatives and their production method

Country Status (1)

Country Link
JP (1) JPS6034940B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578503A (en) * 1982-08-31 1986-03-25 Daikin Kogyo Co., Ltd. Alkylated or alkenylated malonic acid or its derivatives having a fluorine
EP1729820A2 (en) * 2004-01-15 2006-12-13 NST Neurosurvival Technologies Ltd. Perturbed membrane-binding compounds and methods of using the same
US7947253B2 (en) * 2004-01-15 2011-05-24 Aposense Ltd. Perturbed membrane-binding compounds and methods of using the same
US20120157296A1 (en) * 2010-12-21 2012-06-21 Linfeng Chen Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same
JP2020526504A (en) * 2017-06-30 2020-08-31 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Substituted quinolinyl cyclohexylpropanamide compound and improved method for its production

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578503A (en) * 1982-08-31 1986-03-25 Daikin Kogyo Co., Ltd. Alkylated or alkenylated malonic acid or its derivatives having a fluorine
EP1729820A2 (en) * 2004-01-15 2006-12-13 NST Neurosurvival Technologies Ltd. Perturbed membrane-binding compounds and methods of using the same
EP1729820A4 (en) * 2004-01-15 2009-11-11 Nst Neurosurvival Technologies Perturbed membrane-binding compounds and methods of using the same
US7947253B2 (en) * 2004-01-15 2011-05-24 Aposense Ltd. Perturbed membrane-binding compounds and methods of using the same
US20120157296A1 (en) * 2010-12-21 2012-06-21 Linfeng Chen Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same
US8383540B2 (en) * 2010-12-21 2013-02-26 Dow Global Technologies Llc Catalyst composition with halo-malonate internal electron donor and polymer from same
JP2020526504A (en) * 2017-06-30 2020-08-31 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Substituted quinolinyl cyclohexylpropanamide compound and improved method for its production
US11919863B2 (en) 2017-06-30 2024-03-05 Bristol-Myers Squibb Company Substituted quinolinylcyclohexylpropanamide compounds and improved methods for their preparation

Also Published As

Publication number Publication date
JPS6034940B2 (en) 1985-08-12

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