JPS57150688A - Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing same - Google Patents
Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing sameInfo
- Publication number
- JPS57150688A JPS57150688A JP57019038A JP1903882A JPS57150688A JP S57150688 A JPS57150688 A JP S57150688A JP 57019038 A JP57019038 A JP 57019038A JP 1903882 A JP1903882 A JP 1903882A JP S57150688 A JPS57150688 A JP S57150688A
- Authority
- JP
- Japan
- Prior art keywords
- furo
- manufacture
- composition containing
- medicinal composition
- containing same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8104072 | 1981-02-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57150688A true JPS57150688A (en) | 1982-09-17 |
JPH0261477B2 JPH0261477B2 (US07902200-20110308-C00112.png) | 1990-12-20 |
Family
ID=10519587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP57019038A Granted JPS57150688A (en) | 1981-02-10 | 1982-02-10 | Furo(3,4-c)pyridine derivative, manufacture and medicinal composition containing same |
Country Status (34)
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59193888A (ja) * | 1983-04-05 | 1984-11-02 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカ−シヨン・シヤンテイフイツク・(エス.セ−.エ−ル.ア−.エス) | フロ−(3,4−c)−ピリジン誘導体、その製造法及びそれを含有する医薬 |
JPS60104090A (ja) * | 1983-10-18 | 1985-06-08 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・(エス.セー.エール.アー.エス) | 4―クロロ―フロ―(3,4―c)―ピリジン誘導体、その製造法並びに利尿及び降圧組成物 |
JPH02504394A (ja) * | 1988-04-06 | 1990-12-13 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・(エス.セー.エール.アー.エス) | フロ〔3,4‐c〕ピリジン鏡像体の立体特異的製造方法、かくして得られた化合物及びこれの製薬組成物 |
JP2011529892A (ja) * | 2008-07-29 | 2011-12-15 | メルク・シャープ・エンド・ドーム・コーポレイション | フロセミドのニトロ誘導体及び利尿剤としてのその使用 |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4735950A (en) * | 1983-04-05 | 1988-04-05 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) | Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same |
GB8330517D0 (en) * | 1983-11-16 | 1983-12-21 | Scras | 6-vinyl-furo-(3,4-c)pyridine derivatives |
GB8330658D0 (en) * | 1983-11-17 | 1983-12-29 | Scras | 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives |
GB8402740D0 (en) * | 1984-02-02 | 1984-03-07 | Scras | Furo-(3 4-c)-pyridine derivatives |
GB8414559D0 (en) * | 1984-06-07 | 1984-07-11 | Scras | Pyridine derivatives |
GB8422379D0 (en) * | 1984-09-05 | 1984-10-10 | Scras | Derivatives |
GB8427218D0 (en) * | 1984-10-27 | 1984-12-05 | Scras | Pyridine derivatives |
DE3519693A1 (de) * | 1985-06-01 | 1987-01-02 | Basf Ag | Pyridin-derivate, ihre herstellung und verwendung |
DE3990349T1 (de) * | 1988-04-06 | 1990-04-26 | Scras | Stereospezifisches verfahren zur herstellung von enantiomeren von furo(3,4-c)pyridin, so erhaltene verbindungen und therapeutische zusammensetzungen auf basis dieser verbindungen |
GB8907480D0 (en) * | 1989-04-03 | 1989-05-17 | Scaras Societe De Conseils De | Separation of insomers of furo(3,4-c)pyridine derivatives |
GB8917168D0 (en) * | 1989-07-27 | 1989-09-13 | Scras | Asymmetric synthesis of furo(3,4-c)pyridine derivatives |
US5130252A (en) * | 1990-05-14 | 1992-07-14 | Synthetech, Inc. | Resolution of furopyridine enantiomers and synthetic precursors thereof |
GB0221494D0 (en) * | 2002-09-16 | 2002-10-23 | Generics Uk Ltd | Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives |
HUP0300990A2 (hu) * | 2003-04-15 | 2005-05-30 | SynoSens Kutató és Fejlesztő Kft. | Szinergista gyógyszer-kombináció a diabetesz megelőzésére vagy kezelésére |
US20060089374A1 (en) * | 2003-07-17 | 2006-04-27 | Glenn Cornett | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
CA2532807A1 (en) * | 2003-07-17 | 2005-02-03 | Cotherix, Inc. | Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome |
US20060154959A1 (en) * | 2005-01-13 | 2006-07-13 | Navitas Pharma | Combination therapies of cicletanine and carvedilol |
EP1804795A4 (en) * | 2004-09-22 | 2007-11-07 | Cornett Glen | ENANTIOMERIC COMPOSITIONS OF CICLETANINE, ALONE OR COMBINED WITH OTHER AGENTS, USED FOR THERAPEUTIC PURPOSES |
US20060153934A1 (en) * | 2005-01-13 | 2006-07-13 | Navitas Pharma | Combination therapies of cicletanine and magnesium |
US20070141174A1 (en) * | 2005-01-13 | 2007-06-21 | Navitas Pharma, Inc. | Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension |
US20080096915A1 (en) * | 2005-01-13 | 2008-04-24 | Greenberg Traurig LLP | Compositions for the treatment of metabolic disorders |
US20070105817A1 (en) * | 2005-11-09 | 2007-05-10 | Jim Page | Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension |
WO2008085872A1 (en) * | 2007-01-03 | 2008-07-17 | Cornett Glenn V | Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders |
US8214941B2 (en) | 2008-10-02 | 2012-07-10 | Kohler Co. | Slip-fit clamping system for mounting a fitting on a wall |
WO2011043914A1 (en) * | 2009-10-09 | 2011-04-14 | Merck Sharp & Dohme Corp. | Diuretics |
WO2011053519A1 (en) * | 2009-10-29 | 2011-05-05 | Merck Sharp & Dohme Corp. | Diuretics |
WO2015103445A1 (en) * | 2013-12-31 | 2015-07-09 | Rockey Don C | Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA786269B (en) * | 1977-11-25 | 1979-10-31 | Scras | New pyridine derivative,its preparation and use |
-
1982
- 1982-01-06 IN IN11/DEL/82A patent/IN156817B/en unknown
- 1982-01-08 US US06/338,140 patent/US4383998A/en not_active Expired - Lifetime
- 1982-01-11 ZA ZA82158A patent/ZA82158B/xx unknown
- 1982-01-11 IL IL64759A patent/IL64759A/xx unknown
- 1982-01-12 GR GR66981A patent/GR75905B/el unknown
- 1982-01-15 BE BE0/207069A patent/BE891797A/fr not_active IP Right Cessation
- 1982-01-19 NL NLAANVRAGE8200180,A patent/NL186697C/xx not_active IP Right Cessation
- 1982-01-20 NZ NZ199528A patent/NZ199528A/en unknown
- 1982-01-21 LU LU83886A patent/LU83886A1/fr unknown
- 1982-01-21 AR AR288193A patent/AR230284A1/es active
- 1982-01-28 NO NO820253A patent/NO156373C/no not_active IP Right Cessation
- 1982-01-28 CH CH508/82A patent/CH649554A5/fr not_active IP Right Cessation
- 1982-01-28 OA OA57599A patent/OA07003A/xx unknown
- 1982-02-01 MA MA19583A patent/MA19378A1/fr unknown
- 1982-02-04 FI FI820353A patent/FI75347C/fi not_active IP Right Cessation
- 1982-02-05 YU YU253/82A patent/YU44000B/xx unknown
- 1982-02-07 DZ DZ826443A patent/DZ376A1/fr active
- 1982-02-08 GB GB8203522A patent/GB2092586B/en not_active Expired
- 1982-02-08 IT IT19502/82A patent/IT1157252B/it active
- 1982-02-09 PT PT74408A patent/PT74408B/pt unknown
- 1982-02-09 MX MX829909U patent/MX6983E/es unknown
- 1982-02-09 AU AU80294/82A patent/AU545876B2/en not_active Expired
- 1982-02-09 IE IE288/82A patent/IE52376B1/en not_active IP Right Cessation
- 1982-02-09 SE SE8200744A patent/SE456994B/sv not_active IP Right Cessation
- 1982-02-09 DK DK054382A patent/DK157551C/da not_active IP Right Cessation
- 1982-02-09 ES ES509449A patent/ES509449A0/es active Granted
- 1982-02-09 KR KR8200536A patent/KR870000206B1/ko active
- 1982-02-09 CA CA000395857A patent/CA1175837A/en not_active Expired
- 1982-02-10 FR FR8202136A patent/FR2499406A1/fr active Granted
- 1982-02-10 FR FR8202137A patent/FR2499574A1/fr active Granted
- 1982-02-10 DE DE19823204596 patent/DE3204596A1/de active Granted
- 1982-02-10 HU HU82405A patent/HU185088B/hu unknown
- 1982-02-10 JP JP57019038A patent/JPS57150688A/ja active Granted
-
1984
- 1984-11-29 SG SG853/84A patent/SG85384G/en unknown
-
1985
- 1985-03-21 HK HK224/85A patent/HK22485A/xx not_active IP Right Cessation
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59193888A (ja) * | 1983-04-05 | 1984-11-02 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカ−シヨン・シヤンテイフイツク・(エス.セ−.エ−ル.ア−.エス) | フロ−(3,4−c)−ピリジン誘導体、その製造法及びそれを含有する医薬 |
JPH0556353B2 (US07902200-20110308-C00112.png) * | 1983-04-05 | 1993-08-19 | Scras | |
JPS60104090A (ja) * | 1983-10-18 | 1985-06-08 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・(エス.セー.エール.アー.エス) | 4―クロロ―フロ―(3,4―c)―ピリジン誘導体、その製造法並びに利尿及び降圧組成物 |
JPH0339513B2 (US07902200-20110308-C00112.png) * | 1983-10-18 | 1991-06-14 | Konseiyu Do Rusherushu E Dapurikashion Shianteifuiiku Scras Soc | |
JPH02504394A (ja) * | 1988-04-06 | 1990-12-13 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・(エス.セー.エール.アー.エス) | フロ〔3,4‐c〕ピリジン鏡像体の立体特異的製造方法、かくして得られた化合物及びこれの製薬組成物 |
JP2680456B2 (ja) * | 1988-04-06 | 1997-11-19 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・(エス.セー.エール.アー.エス) | フロ〔3,4―c〕ピリジン鏡像体の立体特異的製造方法 |
JP2011529892A (ja) * | 2008-07-29 | 2011-12-15 | メルク・シャープ・エンド・ドーム・コーポレイション | フロセミドのニトロ誘導体及び利尿剤としてのその使用 |
Also Published As
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