JPS57136581A - Preparation of 1,5-benzothiazepin derivative - Google Patents
Preparation of 1,5-benzothiazepin derivativeInfo
- Publication number
- JPS57136581A JPS57136581A JP2141281A JP2141281A JPS57136581A JP S57136581 A JPS57136581 A JP S57136581A JP 2141281 A JP2141281 A JP 2141281A JP 2141281 A JP2141281 A JP 2141281A JP S57136581 A JPS57136581 A JP S57136581A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- benzothiazepin
- compound
- alumina
- silica gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KJFRSZASZNLCDF-UHFFFAOYSA-N 1,5-benzothiazepine Chemical class S1C=CC=NC2=CC=CC=C12 KJFRSZASZNLCDF-UHFFFAOYSA-N 0.000 title abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002798 polar solvent Substances 0.000 abstract 2
- 239000000741 silica gel Substances 0.000 abstract 2
- 229910002027 silica gel Inorganic materials 0.000 abstract 2
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 210000004351 coronary vessel Anatomy 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910000104 sodium hydride Inorganic materials 0.000 abstract 1
- 239000012312 sodium hydride Substances 0.000 abstract 1
- HXJUTPCZVOIRIF-UHFFFAOYSA-N sulfolane Chemical compound O=S1(=O)CCCC1 HXJUTPCZVOIRIF-UHFFFAOYSA-N 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2141281A JPS57136581A (en) | 1981-02-18 | 1981-02-18 | Preparation of 1,5-benzothiazepin derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2141281A JPS57136581A (en) | 1981-02-18 | 1981-02-18 | Preparation of 1,5-benzothiazepin derivative |
Related Child Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6868984A Division JPS59231074A (ja) | 1984-04-05 | 1984-04-05 | １，５−ベンゾチアゼピン誘導体の製法 |
| JP6869184A Division JPS59231075A (ja) | 1984-04-05 | 1984-04-05 | １，５−ベンゾチアゼピン誘導体の製法 |
| JP6869084A Division JPS59231065A (ja) | 1984-04-05 | 1984-04-05 | プロピオン酸誘導体の光学分割方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57136581A true JPS57136581A (en) | 1982-08-23 |
| JPS6317831B2 JPS6317831B2 (enrdf_load_stackoverflow) | 1988-04-15 |
Family
ID=12054302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2141281A Granted JPS57136581A (en) | 1981-02-18 | 1981-02-18 | Preparation of 1,5-benzothiazepin derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57136581A (enrdf_load_stackoverflow) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985000810A1 (en) * | 1983-08-12 | 1985-02-28 | Takeda Chemical Industries, Ltd. | Fused 7-membered ring compounds and process for their preparation |
| WO1985001730A1 (en) * | 1983-10-13 | 1985-04-25 | Takeda Chemical Industries, Ltd. | Fused 7-membered ring compounds and process for their preparation |
| JPS60155168A (ja) * | 1984-01-24 | 1985-08-15 | Toubishi Yakuhin Kogyo Kk | １，５−ベンゾチアゼピン誘導体の製造法 |
| US4552695A (en) * | 1983-04-21 | 1985-11-12 | Shionogi & Co., Ltd. | Process for production of diltiazem hydrochloride |
| JPS6133164A (ja) * | 1984-07-25 | 1986-02-17 | Nippon Chemiphar Co Ltd | プロピオン酸誘導体の光学分割方法 |
| JPS6165875A (ja) * | 1984-09-06 | 1986-04-04 | Toubishi Yakuhin Kogyo Kk | １，５−ベンゾチアゼピン誘導体の製法 |
| JPS61145159A (ja) * | 1984-12-20 | 1986-07-02 | Nippon Chemiphar Co Ltd | 新規な光学活性プロピオン酸エステル誘導体およびその製造法 |
| JPS61145160A (ja) * | 1984-12-20 | 1986-07-02 | Nippon Chemiphar Co Ltd | 光学活性なプロピオン酸誘導体の製造法 |
| JPH021466A (ja) * | 1988-01-28 | 1990-01-05 | Ind Chim Profarmaco Spa | ラセミ酸の光学的分割方法 |
-
1981
- 1981-02-18 JP JP2141281A patent/JPS57136581A/ja active Granted
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4552695A (en) * | 1983-04-21 | 1985-11-12 | Shionogi & Co., Ltd. | Process for production of diltiazem hydrochloride |
| WO1985000810A1 (en) * | 1983-08-12 | 1985-02-28 | Takeda Chemical Industries, Ltd. | Fused 7-membered ring compounds and process for their preparation |
| WO1985001730A1 (en) * | 1983-10-13 | 1985-04-25 | Takeda Chemical Industries, Ltd. | Fused 7-membered ring compounds and process for their preparation |
| JPS60155168A (ja) * | 1984-01-24 | 1985-08-15 | Toubishi Yakuhin Kogyo Kk | １，５−ベンゾチアゼピン誘導体の製造法 |
| JPS6133164A (ja) * | 1984-07-25 | 1986-02-17 | Nippon Chemiphar Co Ltd | プロピオン酸誘導体の光学分割方法 |
| JPS6165875A (ja) * | 1984-09-06 | 1986-04-04 | Toubishi Yakuhin Kogyo Kk | １，５−ベンゾチアゼピン誘導体の製法 |
| JPS61145159A (ja) * | 1984-12-20 | 1986-07-02 | Nippon Chemiphar Co Ltd | 新規な光学活性プロピオン酸エステル誘導体およびその製造法 |
| JPS61145160A (ja) * | 1984-12-20 | 1986-07-02 | Nippon Chemiphar Co Ltd | 光学活性なプロピオン酸誘導体の製造法 |
| JPH021466A (ja) * | 1988-01-28 | 1990-01-05 | Ind Chim Profarmaco Spa | ラセミ酸の光学的分割方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6317831B2 (enrdf_load_stackoverflow) | 1988-04-15 |
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