JPS5422995B2 - - Google Patents

Info

Publication number
JPS5422995B2
JPS5422995B2 JP1336078A JP1336078A JPS5422995B2 JP S5422995 B2 JPS5422995 B2 JP S5422995B2 JP 1336078 A JP1336078 A JP 1336078A JP 1336078 A JP1336078 A JP 1336078A JP S5422995 B2 JPS5422995 B2 JP S5422995B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP1336078A
Other versions
JPS53116386A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS53116386A publication Critical patent/JPS53116386A/ja
Publication of JPS5422995B2 publication Critical patent/JPS5422995B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP1336078A 1971-10-29 1978-02-08 Method of producing novel hydroxypyrimidines Granted JPS53116386A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (2)

Publication Number Publication Date
JPS53116386A JPS53116386A (en) 1978-10-11
JPS5422995B2 true JPS5422995B2 (ja) 1979-08-10

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10279972A Expired JPS5337870B2 (ja) 1971-10-29 1972-10-16
JP1336078A Granted JPS53116386A (en) 1971-10-29 1978-02-08 Method of producing novel hydroxypyrimidines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP10279972A Expired JPS5337870B2 (ja) 1971-10-29 1972-10-16

Country Status (25)

Country Link
JP (2) JPS5337870B2 (ja)
AR (2) AR198798A1 (ja)
AT (2) AT320656B (ja)
AU (1) AU467600B2 (ja)
BE (1) BE790125A (ja)
CA (1) CA980778A (ja)
CH (2) CH555832A (ja)
DE (3) DE2248741C3 (ja)
DK (1) DK131465B (ja)
EG (1) EG11013A (ja)
ES (2) ES407730A1 (ja)
FI (1) FI55503C (ja)
FR (1) FR2157865B1 (ja)
GB (2) GB1377308A (ja)
IE (1) IE37043B1 (ja)
IL (2) IL40458A (ja)
LU (1) LU66304A1 (ja)
NL (1) NL166470C (ja)
NO (1) NO136574C (ja)
PH (2) PH10129A (ja)
PL (2) PL84634B1 (ja)
SE (2) SE393376B (ja)
SU (2) SU498908A3 (ja)
YU (2) YU35125B (ja)
ZA (1) ZA727362B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (ja) * 1979-04-17 1980-11-01
JPS5752409Y2 (ja) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 ｐ−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
JP5113752B2 (ja) 2005-08-22 2013-01-09 メリオール・ファーマスーティカルズ・ワン・インコーポレイテッド Ｌｙｎキナーゼの活性を調節し、関連する疾患を治療するための方法および製剤
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
MX2019012170A (es) 2017-04-10 2020-01-20 Melior Pharmaceuticals I Inc Tratamiento de adipocitos.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
NL7213959A (ja) 1973-05-02
NO136574B (ja) 1977-06-20
ES436624A1 (es) 1977-02-01
DE2264657C2 (de) 1982-09-16
YU36295B (en) 1982-06-18
BE790125A (fr) 1973-04-16
AU467600B2 (en) 1975-12-04
DE2248741C3 (de) 1975-06-26
FI55503B (fi) 1979-04-30
AT321308B (de) 1975-03-25
DE2264374C3 (de) 1981-07-23
PL89852B1 (ja) 1976-12-31
IE37043B1 (en) 1977-04-27
SU505362A3 (ru) 1976-02-28
YU255172A (en) 1980-03-15
EG11013A (en) 1976-11-30
AT320656B (de) 1975-02-25
JPS5337870B2 (ja) 1978-10-12
SE397090B (sv) 1977-10-17
SE7505279L (sv) 1975-05-06
NO136574C (no) 1977-09-28
IL40458A (en) 1976-05-31
DE2264374B2 (de) 1980-08-07
YU35125B (en) 1980-09-25
IL48790A0 (en) 1976-03-31
ZA727362B (en) 1973-11-28
YU99179A (en) 1981-08-31
LU66304A1 (ja) 1973-05-03
GB1377720A (en) 1974-12-18
FI55503C (fi) 1979-08-10
PL84634B1 (ja) 1976-04-30
CH555832A (fr) 1974-11-15
IL48790A (en) 1976-05-31
DE2264657A1 (de) 1974-06-20
AU4722872A (en) 1974-04-04
IL40458A0 (en) 1972-11-28
DK131465B (da) 1975-07-21
FR2157865A1 (ja) 1973-06-08
PH10129A (en) 1976-09-02
ES407730A1 (es) 1976-01-16
NL166470C (nl) 1981-08-17
GB1377308A (en) 1974-12-11
CA980778A (en) 1975-12-30
JPS4852780A (ja) 1973-07-24
PH11594A (en) 1978-03-31
CH549579A (fr) 1974-05-31
DE2248741B2 (de) 1974-11-14
SU498908A3 (ru) 1976-01-05
IE37043L (en) 1973-04-29
FR2157865B1 (ja) 1975-10-31
AR198798A1 (es) 1974-07-24
DE2264374A1 (de) 1973-05-24
AR196263A1 (es) 1973-12-10
DK131465C (ja) 1975-12-08
NL166470B (nl) 1981-03-16
SE393376B (sv) 1977-05-09
DE2248741A1 (de) 1973-05-03
JPS53116386A (en) 1978-10-11

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