|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
US6794390B2
(en)
*
|
1996-08-02 |
2004-09-21 |
Cv Therapeutics, Inc. |
Purine inhibitors of cyclin dependent kinase 2 & ikappabalpha
|
|
US6790958B2
(en)
*
|
1996-08-02 |
2004-09-14 |
Robert T. Lum |
Purine inhibitors of cyclin dependent kinase 2 & IKBA
|
|
US5866702A
(en)
*
|
1996-08-02 |
1999-02-02 |
Cv Therapeutics, Incorporation |
Purine inhibitors of cyclin dependent kinase 2
|
|
AU4920397A
(en)
*
|
1996-10-11 |
1998-05-11 |
Chiron Corporation |
Purine inhibitors of glycogen synthase kinase 3 (gsk3)
|
|
US6432947B1
(en)
*
|
1997-02-19 |
2002-08-13 |
Berlex Laboratories, Inc. |
N-heterocyclic derivatives as NOS inhibitors
|
|
CA2297967A1
(en)
|
1997-08-07 |
1999-02-18 |
The Regents Of The University Of California |
Purine inhibitor of protein kinases, g proteins and polymerases
|
|
US6573044B1
(en)
|
1997-08-07 |
2003-06-03 |
The Regents Of The University Of California |
Methods of using chemical libraries to search for new kinase inhibitors
|
|
NZ503788A
(en)
|
1997-10-27 |
2002-11-26 |
Agouron Pharma |
4-aminothiazole derivatives and their use as inhibitors of cyclin-dependent kinases
|
|
AU1631699A
(en)
*
|
1997-12-18 |
1999-07-05 |
E.I. Du Pont De Nemours And Company |
Cyclohexylamine arthropodicides and fungicides
|
|
US6642231B2
(en)
*
|
1998-02-26 |
2003-11-04 |
Aventis Pharmaceuticals Inc. |
6,9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
|
|
DE69912248T2
(de)
*
|
1998-02-26 |
2004-04-22 |
Aventis Pharmaceuticals Inc. |
6,9-disubstituierte 2-[trans-(4-aminocyclohexyl)amino] purine
|
|
US6479487B1
(en)
*
|
1998-02-26 |
2002-11-12 |
Aventis Pharmaceuticals Inc. |
6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
|
|
US6413974B1
(en)
*
|
1998-02-26 |
2002-07-02 |
Aventis Pharmaceuticals Inc. |
6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
|
|
IL138044A0
(en)
*
|
1998-02-26 |
2001-10-31 |
Aventis Pharma Inc |
6,9-disubstituted 2-[trans- 4-aminocyclohexyl) amino] purines
|
|
CZ27399A3
(cs)
*
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
|
GB9903762D0
(en)
*
|
1999-02-18 |
1999-04-14 |
Novartis Ag |
Organic compounds
|
|
US7125875B2
(en)
|
1999-04-15 |
2006-10-24 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
|
FR2793794B1
(fr)
*
|
1999-05-21 |
2001-07-27 |
Hoechst Marion Roussel Inc |
Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
|
|
GB9918035D0
(en)
*
|
1999-07-30 |
1999-09-29 |
Novartis Ag |
Organic compounds
|
|
ATE322494T1
(de)
*
|
2000-01-07 |
2006-04-15 |
Universitaire Instelling Antwe |
Purin derivate, ihre herstellung und verwendung
|
|
WO2001082967A1
(fr)
*
|
2000-04-28 |
2001-11-08 |
Yamanouchi Pharmaceutical Co., Ltd. |
Compositions medicinales destinees a supprimer la production de ?-amyloide
|
|
US6861524B2
(en)
|
2000-10-31 |
2005-03-01 |
Aventis Pharmaceuticals Inc. |
Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
|
|
FR2818642B1
(fr)
|
2000-12-26 |
2005-07-15 |
Hoechst Marion Roussel Inc |
Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion
|
|
PE20030008A1
(es)
|
2001-06-19 |
2003-01-22 |
Bristol Myers Squibb Co |
Inhibidores duales de pde 7 y pde 4
|
|
EP1399446B1
(en)
|
2001-06-27 |
2005-08-03 |
Cyclacel Limited |
2,6,9-substituted purine derivatives and their use in the treatment of proliferative disorders
|
|
CZ294535B6
(cs)
*
|
2001-08-02 |
2005-01-12 |
Ústav Experimentální Botaniky Avčr |
Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
|
|
CA2450777C
(en)
|
2001-08-10 |
2013-04-09 |
Novartis Ag |
Use of c-src inhibitors alone or in combination with sti571 for the treatment of leukaemia
|
|
EP1578722A4
(en)
*
|
2001-10-12 |
2006-09-06 |
Irm Llc |
KINASEINHIBITOR SCAFFOLD AND METHOD FOR THE PRODUCTION THEREOF
|
|
GB0219054D0
(en)
|
2002-08-15 |
2002-09-25 |
Cyclacel Ltd |
New purine derivatives
|
|
GB0219052D0
(en)
|
2002-08-15 |
2002-09-25 |
Cyclacel Ltd |
New puring derivatives
|
|
AR041292A1
(es)
|
2002-09-19 |
2005-05-11 |
Schering Corp |
Pirazolopiridinas como inhibidores de quinasa dependientes de ciclina
|
|
WO2004035132A2
(en)
*
|
2002-10-15 |
2004-04-29 |
Irm Llc |
Compositions and methods for inducing osteogenesis
|
|
JP2006521398A
(ja)
*
|
2003-03-28 |
2006-09-21 |
サイオス・インコーポレーテツド |
ＴＧＦβの二−環式ピリミジン阻害剤
|
|
US7173031B2
(en)
*
|
2004-06-28 |
2007-02-06 |
Bristol-Myers Squibb Company |
Pyrrolotriazine kinase inhibitors
|
|
US7439246B2
(en)
|
2004-06-28 |
2008-10-21 |
Bristol-Myers Squibb Company |
Fused heterocyclic kinase inhibitors
|
|
JP5400388B2
(ja)
*
|
2005-12-15 |
2014-01-29 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
キナーゼインヒビターおよびその利用
|
|
BRPI0720264B1
(pt)
*
|
2006-12-08 |
2022-03-03 |
Novartis Ag |
Compostos e composições como inibidores de proteína cinase
|
|
EP2311807B1
(en)
|
2006-12-08 |
2015-11-11 |
Novartis AG |
Compounds and composition as protein kinase inhibitors
|
|
EP2132208A1
(en)
*
|
2007-03-28 |
2009-12-16 |
NeuroSearch AS |
Purinyl derivatives and their use as potassium channel modulators
|
|
JP2010522719A
(ja)
*
|
2007-03-28 |
2010-07-08 |
ノイロサーチ アクティーゼルスカブ |
プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用
|
|
CZ302225B6
(cs)
*
|
2007-07-04 |
2010-12-29 |
Univerzita Palackého v Olomouci |
Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny
|
|
US8592432B2
(en)
*
|
2008-04-07 |
2013-11-26 |
Bei Chen |
Compounds and compositions as protein kinase inhibitors
|
|
EP2344501A1
(en)
*
|
2008-09-26 |
2011-07-20 |
NeuroSearch A/S |
Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators
|
|
WO2010034707A1
(en)
|
2008-09-26 |
2010-04-01 |
Neurosearch A/S |
Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators
|
|
BR112013023050A8
(pt)
|
2011-03-09 |
2018-09-25 |
G Pestell Richard |
antagonista de ccr5, método para determinar se um indivíduo humano tendo câncer de próstata está sofrendo de ou sob o risco de desenvolver metástase, para identificar um antagonista de ccr5, método para determinar se um indivíduo humano tendo câncer de próstata está sofrendo de ou sob o risco de desenvolver metástase, para identificar um composto candidato, para produzir in vitro células epiteliais primárias, para diagnosticar câncer de próstata, para selecionar um tratamento para um indivíduo tendo um câncer/tumor de próstata, linhagem de célula, e, modelo animal
|
|
CA2856291C
(en)
|
2011-11-17 |
2020-08-11 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-jun-n-terminal kinase (jnk)
|
|
AU2013262977A1
(en)
|
2012-05-14 |
2015-01-22 |
Prostagene, Llc |
Using modulators of CCR5 for treating cancer
|
|
CA2876780A1
(en)
|
2012-06-26 |
2014-01-03 |
Saniona Aps |
A phenyl triazole derivative and its use for modulating the gabaa receptor complex
|
|
CN105283206B
(zh)
*
|
2013-03-27 |
2019-11-08 |
财团法人峨山社会福祉财团 |
包含p34的表达抑制剂或活性抑制剂作为有效成分的用于治疗或转移抑制癌的组合物
|
|
US10047070B2
(en)
|
2013-10-18 |
2018-08-14 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
US11920164B2
(en)
|
2014-07-30 |
2024-03-05 |
Yeda Research And Development Co. Ltd. |
Media for culturing naive human pluripotent stem cells
|
|
AU2015371251B2
(en)
|
2014-12-23 |
2020-06-11 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (CDK7)
|
|
HK1246645A1
(zh)
*
|
2015-03-27 |
2018-09-14 |
达纳-法伯癌症研究所股份有限公司 |
细胞周期蛋白依赖性激酶的抑制剂
|
|
EP3347018B1
(en)
|
2015-09-09 |
2021-09-01 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
CN114149432B
(zh)
*
|
2016-09-30 |
2024-07-05 |
斯坦福国际研究院 |
用于癌症治疗的双重clk/cdk1抑制剂
|
|
US12187701B2
(en)
|
2018-06-25 |
2025-01-07 |
Dana-Farber Cancer Institute, Inc. |
Taire family kinase inhibitors and uses thereof
|
|
WO2020152686A1
(en)
|
2019-01-23 |
2020-07-30 |
Yeda Research And Development Co. Ltd. |
Culture media for pluripotent stem cells
|
|
CN120289460A
(zh)
*
|
2024-01-09 |
2025-07-11 |
中国科学院合肥物质科学研究院 |
含有嘌呤环的化合物及其用途
|