|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
US6794390B2
(en)
*
|
1996-08-02 |
2004-09-21 |
Cv Therapeutics, Inc. |
Purine inhibitors of cyclin dependent kinase 2 & ikappabalpha
|
|
US6790958B2
(en)
*
|
1996-08-02 |
2004-09-14 |
Robert T. Lum |
Purine inhibitors of cyclin dependent kinase 2 & IKBA
|
|
US5866702A
(en)
*
|
1996-08-02 |
1999-02-02 |
Cv Therapeutics, Incorporation |
Purine inhibitors of cyclin dependent kinase 2
|
|
WO1998016528A1
(en)
*
|
1996-10-11 |
1998-04-23 |
Chiron Corporation |
Purine inhibitors of glycogen synthase kinase 3 (gsk3)
|
|
US6432947B1
(en)
*
|
1997-02-19 |
2002-08-13 |
Berlex Laboratories, Inc. |
N-heterocyclic derivatives as NOS inhibitors
|
|
US6255485B1
(en)
|
1997-08-07 |
2001-07-03 |
The Regents Of The University Of California |
Purine inhibitors of protein kinases, G proteins and polymerases
|
|
US6573044B1
(en)
|
1997-08-07 |
2003-06-03 |
The Regents Of The University Of California |
Methods of using chemical libraries to search for new kinase inhibitors
|
|
PL342447A1
(en)
|
1997-10-27 |
2001-06-04 |
Agouron Pharma |
Substituted 4-amino thiazol-2-yl compounds as inhibitors of cyclin-dependent kinases
|
|
WO1999031072A1
(en)
*
|
1997-12-18 |
1999-06-24 |
E.I. Du Pont De Nemours And Company |
Cyclohexylamine arthropodicides and fungicides
|
|
US6642231B2
(en)
*
|
1998-02-26 |
2003-11-04 |
Aventis Pharmaceuticals Inc. |
6,9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
|
|
TR200002482T2
(tr)
*
|
1998-02-26 |
2002-10-21 |
Aventis Pharmaceuticals Inc. |
6,9-Diikameli 2-(Trans-(4-Aminosiklohekzil) Amino)Pürinler
|
|
UA66840C2
(uk)
*
|
1998-02-26 |
2004-06-15 |
Авентіс Фармасьютікалз Інк. |
6,9-дизаміщені 2-[транс-(4-аміноциклогексил)аміно]пурини, фармацевтична композиція та способи лікування проліферативного розладу, попередження апоптозу нервових клітин, захисту нервових клітин від руйнування
|
|
US6479487B1
(en)
|
1998-02-26 |
2002-11-12 |
Aventis Pharmaceuticals Inc. |
6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
|
|
US6413974B1
(en)
*
|
1998-02-26 |
2002-07-02 |
Aventis Pharmaceuticals Inc. |
6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
|
|
CZ27399A3
(cs)
*
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
|
GB9903762D0
(en)
*
|
1999-02-18 |
1999-04-14 |
Novartis Ag |
Organic compounds
|
|
US7125875B2
(en)
|
1999-04-15 |
2006-10-24 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
|
FR2793794B1
(fr)
*
|
1999-05-21 |
2001-07-27 |
Hoechst Marion Roussel Inc |
Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
|
|
GB9918035D0
(en)
*
|
1999-07-30 |
1999-09-29 |
Novartis Ag |
Organic compounds
|
|
IL150594A0
(en)
*
|
2000-01-07 |
2003-02-12 |
Ustav Ex Botan Adademie Ved Ce |
Purine derivatives, process for their preparation and use
|
|
WO2001082967A1
(fr)
*
|
2000-04-28 |
2001-11-08 |
Yamanouchi Pharmaceutical Co., Ltd. |
Compositions medicinales destinees a supprimer la production de ?-amyloide
|
|
US6861524B2
(en)
|
2000-10-31 |
2005-03-01 |
Aventis Pharmaceuticals Inc. |
Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
|
|
FR2818642B1
(fr)
|
2000-12-26 |
2005-07-15 |
Hoechst Marion Roussel Inc |
Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion
|
|
PE20030008A1
(es)
|
2001-06-19 |
2003-01-22 |
Bristol Myers Squibb Co |
Inhibidores duales de pde 7 y pde 4
|
|
DE60205376T2
(de)
|
2001-06-27 |
2006-04-06 |
Cyclacel Ltd. |
2,6,9-substituierte purinderivate und ihre verwendung bei der behandlung proliferativer krankheiten
|
|
CZ294535B6
(cs)
*
|
2001-08-02 |
2005-01-12 |
Ústav Experimentální Botaniky Avčr |
Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
|
|
US20040248906A1
(en)
|
2001-08-10 |
2004-12-09 |
Donato Nicholas J |
Use of c-src inhibitors alone or in combination with st1571 for the treatment of leukaemia
|
|
EP1578722A4
(en)
*
|
2001-10-12 |
2006-09-06 |
Irm Llc |
KINASEINHIBITOR SCAFFOLD AND METHOD FOR THE PRODUCTION THEREOF
|
|
GB0219052D0
(en)
|
2002-08-15 |
2002-09-25 |
Cyclacel Ltd |
New puring derivatives
|
|
GB0219054D0
(en)
|
2002-08-15 |
2002-09-25 |
Cyclacel Ltd |
New purine derivatives
|
|
AR041292A1
(es)
|
2002-09-19 |
2005-05-11 |
Schering Corp |
Pirazolopiridinas como inhibidores de quinasa dependientes de ciclina
|
|
EP1556129A4
(en)
*
|
2002-10-15 |
2011-02-09 |
Irm Llc |
COMPOSITIONS AND METHODS OF INDUCING OSTEOGENESIS
|
|
US7223766B2
(en)
|
2003-03-28 |
2007-05-29 |
Scios, Inc. |
Bi-cyclic pyrimidine inhibitors of TGFβ
|
|
US7439246B2
(en)
|
2004-06-28 |
2008-10-21 |
Bristol-Myers Squibb Company |
Fused heterocyclic kinase inhibitors
|
|
US7173031B2
(en)
*
|
2004-06-28 |
2007-02-06 |
Bristol-Myers Squibb Company |
Pyrrolotriazine kinase inhibitors
|
|
WO2007070872A1
(en)
|
2005-12-15 |
2007-06-21 |
Rigel Pharmaceuticals, Inc. |
Kinase inhibitors and their uses
|
|
NZ577197A
(en)
|
2006-12-08 |
2011-02-25 |
Irm Llc |
Pyrimidine compounds especially 4-phenylamino-2-arylamino-pyrimidine derivatives and compositions as protein kinase inhibitors
|
|
EA017405B9
(ru)
*
|
2006-12-08 |
2014-05-30 |
АйАрЭм ЭлЭлСи |
Соединения и композиции в качестве ингибиторов протеинкиназы
|
|
EP2144911A2
(en)
|
2007-03-28 |
2010-01-20 |
NeuroSearch AS |
Purinyl derivatives and their use as potassium channel modulators
|
|
KR101564233B1
(ko)
*
|
2007-03-28 |
2015-10-29 |
뉴로서치 에이/에스 |
푸리닐 유도체 및 칼륨 채널 조절제로서의 이의 용도
|
|
CZ302225B6
(cs)
*
|
2007-07-04 |
2010-12-29 |
Univerzita Palackého v Olomouci |
Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny
|
|
MX2010010968A
(es)
*
|
2008-04-07 |
2010-10-26 |
Irm Llc |
Compuestos y composiciones como inhibidores de cinasa de proteina.
|
|
US20110237607A1
(en)
*
|
2008-09-26 |
2011-09-29 |
Neurosearch A/S |
Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators
|
|
US8268838B2
(en)
|
2008-09-26 |
2012-09-18 |
Neurosearch A/S |
Substituted purinyl-pyrazole derivatives and their use as potassium channel modulators
|
|
AU2012225232B2
(en)
|
2011-03-09 |
2016-05-12 |
Richard G. Pestell |
Prostate cancer cell lines, gene signatures and uses thereof
|
|
US9382239B2
(en)
|
2011-11-17 |
2016-07-05 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-Jun-N-terminal kinase (JNK)
|
|
JP6518585B2
(ja)
|
2012-05-14 |
2019-05-22 |
リチャード ジー． ペステル |
がんの治療のためのｃｃｒ５の修飾薬の使用
|
|
US9475797B2
(en)
|
2012-06-26 |
2016-10-25 |
Saniona A/S |
Phenyl triazole derivative and its use for modulating the GABAA receptor complex
|
|
KR101652010B1
(ko)
*
|
2013-03-27 |
2016-08-29 |
재단법인 아산사회복지재단 |
p34의 발현 억제제 또는 활성 억제제를 유효성분으로 포함하는 암의 치료 또는 전이 억제용 조성물
|
|
EP3057956B1
(en)
|
2013-10-18 |
2021-05-05 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7)
|
|
CN108064274A
(zh)
|
2014-07-30 |
2018-05-22 |
耶达研究及发展有限公司 |
用于培养多能干细胞的培养基
|
|
JP6854762B2
(ja)
|
2014-12-23 |
2021-04-07 |
ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド |
サイクリン依存性キナーゼ７（ｃｄｋ７）の阻害剤
|
|
USRE50776E1
(en)
|
2015-03-27 |
2026-02-03 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
AU2016319125B2
(en)
|
2015-09-09 |
2021-04-08 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
|
US10722515B2
(en)
*
|
2016-09-30 |
2020-07-28 |
Sri International |
Dual CLK/CDK1 inhibitors for cancer treatment
|
|
EP3810132A4
(en)
|
2018-06-25 |
2022-06-22 |
Dana-Farber Cancer Institute, Inc. |
TAIRE FAMILY KINASE INHIBITORS AND RELATED USES
|
|
EP3914698B1
(en)
|
2019-01-23 |
2024-12-11 |
Yeda Research and Development Co. Ltd |
Culture media for pluripotent stem cells
|
|
CN120289460A
(zh)
*
|
2024-01-09 |
2025-07-11 |
中国科学院合肥物质科学研究院 |
含有嘌呤环的化合物及其用途
|