AR004134A1 - Derivados 2-amino-6-anilino-purina y procedimiento y nuevos intermediarios para su preparacion, formulaciones farmaceuticas que comprenden talesderivados y el uso de estos derivados como medicamentos. - Google Patents

Derivados 2-amino-6-anilino-purina y procedimiento y nuevos intermediarios para su preparacion, formulaciones farmaceuticas que comprenden talesderivados y el uso de estos derivados como medicamentos.

Info

Publication number
AR004134A1
AR004134A1 ARP960104961A ARP960104961A AR004134A1 AR 004134 A1 AR004134 A1 AR 004134A1 AR P960104961 A ARP960104961 A AR P960104961A AR P960104961 A ARP960104961 A AR P960104961A AR 004134 A1 AR004134 A1 AR 004134A1
Authority
AR
Argentina
Prior art keywords
derivatives
amino
aniline
medicines
procedure
Prior art date
Application number
ARP960104961A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR004134A1 publication Critical patent/AR004134A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen derivados 2-amino-6-anilino-purina de la fórmula (I), en donde los símbolos son como se definió en la descripción. Estos compuestosinhiben la p34(cdc2)/ciclina B(cdc13) quinasa y pueden ser usados para el tratamiento deenfer medades hiperproliferativas, por ejemplo, enfermedadestumorales.
ARP960104961A 1995-11-01 1996-10-30 Derivados 2-amino-6-anilino-purina y procedimiento y nuevos intermediarios para su preparacion, formulaciones farmaceuticas que comprenden talesderivados y el uso de estos derivados como medicamentos. AR004134A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH309495 1995-11-01
CH221396 1996-09-10

Publications (1)

Publication Number Publication Date
AR004134A1 true AR004134A1 (es) 1998-09-30

Family

ID=25689809

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960104961A AR004134A1 (es) 1995-11-01 1996-10-30 Derivados 2-amino-6-anilino-purina y procedimiento y nuevos intermediarios para su preparacion, formulaciones farmaceuticas que comprenden talesderivados y el uso de estos derivados como medicamentos.

Country Status (14)

Country Link
US (1) US7091346B1 (es)
EP (1) EP0874846B1 (es)
JP (2) JP4004066B2 (es)
CN (1) CN1066147C (es)
AR (1) AR004134A1 (es)
AT (1) ATE236161T1 (es)
AU (1) AU7296896A (es)
BR (1) BR9611157A (es)
CA (1) CA2234609C (es)
DE (1) DE69627195T2 (es)
ES (1) ES2196181T3 (es)
HK (1) HK1016580A1 (es)
PT (1) PT874846E (es)
WO (1) WO1997016452A1 (es)

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US6573044B1 (en) 1997-08-07 2003-06-03 The Regents Of The University Of California Methods of using chemical libraries to search for new kinase inhibitors
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CZ20022353A3 (cs) * 2000-01-07 2003-02-12 Universitaire Instelling Antwerpen Deriváty purinu, způsob jejich přípravy a jejich použití
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PE20030008A1 (es) 2001-06-19 2003-01-22 Bristol Myers Squibb Co Inhibidores duales de pde 7 y pde 4
ATE301123T1 (de) 2001-06-27 2005-08-15 Cyclacel Ltd 2,6,9-substituierte purinderivate und ihre verwendung bei der behandlung proliferativer krankheiten
CN1523991A (zh) 2001-08-10 2004-08-25 ��˹��ŵ�� 单独的c-Src抑制剂或其与STI571的组合用于治疗白血病的用途
AU2002342051B2 (en) * 2001-10-12 2009-06-11 Irm Llc Kinase inhibitor scaffolds and methods for their preparation
GB0219052D0 (en) 2002-08-15 2002-09-25 Cyclacel Ltd New puring derivatives
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US7151104B2 (en) * 2002-09-19 2006-12-19 Schering Corporation Pyrazolopyridines as cyclin dependent kinase inhibitors
AU2003301407B2 (en) * 2002-10-15 2010-04-22 Irm Llc Compositions and methods for inducing osteogenesis
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US7173031B2 (en) * 2004-06-28 2007-02-06 Bristol-Myers Squibb Company Pyrrolotriazine kinase inhibitors
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CA2873743C (en) 2012-05-14 2022-12-06 Prostagene, Llc Using modulators of ccr5 for treating cancer
US9475797B2 (en) 2012-06-26 2016-10-25 Saniona A/S Phenyl triazole derivative and its use for modulating the GABAA receptor complex
KR101652010B1 (ko) * 2013-03-27 2016-08-29 재단법인 아산사회복지재단 p34의 발현 억제제 또는 활성 억제제를 유효성분으로 포함하는 암의 치료 또는 전이 억제용 조성물
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Also Published As

Publication number Publication date
JP2007231023A (ja) 2007-09-13
CA2234609C (en) 2006-11-28
EP0874846A1 (en) 1998-11-04
AU7296896A (en) 1997-05-22
BR9611157A (pt) 1999-03-30
WO1997016452A1 (en) 1997-05-09
DE69627195D1 (de) 2003-05-08
JPH11514336A (ja) 1999-12-07
HK1016580A1 (en) 1999-11-05
PT874846E (pt) 2003-08-29
ATE236161T1 (de) 2003-04-15
DE69627195T2 (de) 2004-01-29
JP4004066B2 (ja) 2007-11-07
US7091346B1 (en) 2006-08-15
CA2234609A1 (en) 1997-05-09
EP0874846B1 (en) 2003-04-02
ES2196181T3 (es) 2003-12-16
CN1066147C (zh) 2001-05-23
CN1202896A (zh) 1998-12-23

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