|
US6309669B1
(en)
*
|
1984-03-16 |
2001-10-30 |
The United States Of America As Represented By The Secretary Of The Army |
Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
|
|
US6406689B1
(en)
|
1995-10-03 |
2002-06-18 |
Frank W. Falkenberg |
Compositions and methods for treatment of tumors and metastatic diseases
|
|
US5942253A
(en)
*
|
1995-10-12 |
1999-08-24 |
Immunex Corporation |
Prolonged release of GM-CSF
|
|
JP3263399B2
(ja)
*
|
1996-05-23 |
2002-03-04 |
サムヤン コーポレーション |
局所投与型生分解性徐放型歯周炎用薬剤組成物及びその製造方法
|
|
KR0181252B1
(ko)
*
|
1996-12-31 |
1999-03-20 |
박원훈 |
에멀젼 방법에 의한 다공성 매트릭스형 서방성 제제의 제조방법
|
|
US7192984B2
(en)
*
|
1997-06-17 |
2007-03-20 |
Fziomed, Inc. |
Compositions of polyacids and polyethers and methods for their use as dermal fillers
|
|
US20040096422A1
(en)
*
|
1997-06-17 |
2004-05-20 |
Schwartz Herbert E. |
Compositions of polyacids and polyethers and methods for their use in reducing pain
|
|
US6869938B1
(en)
*
|
1997-06-17 |
2005-03-22 |
Fziomed, Inc. |
Compositions of polyacids and polyethers and methods for their use in reducing adhesions
|
|
US20050074495A1
(en)
*
|
1997-06-17 |
2005-04-07 |
Fziomed, Inc. |
Compositions of polyacids and methods for their use in reducing adhesions
|
|
AU760034B2
(en)
*
|
1997-08-29 |
2003-05-08 |
Corixa Corporation |
Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of using thereof
|
|
WO1999013865A1
(en)
|
1997-09-18 |
1999-03-25 |
Depotech Corporation |
Sustained-release liposomal anesthetic compositions
|
|
ATE554748T1
(de)
|
1997-11-14 |
2012-05-15 |
Pacira Pharmaceuticals Inc |
Herstellung von multivesikulären liposomen
|
|
US6423345B2
(en)
*
|
1998-04-30 |
2002-07-23 |
Acusphere, Inc. |
Matrices formed of polymer and hydrophobic compounds for use in drug delivery
|
|
US6730322B1
(en)
|
1998-04-30 |
2004-05-04 |
Acusphere, Inc. |
Matrices formed of polymer and hydrophobic compounds for use in drug delivery
|
|
EP1117720A4
(en)
*
|
1998-07-13 |
2001-11-14 |
Expression Genetics Inc |
POLYESTER POLY-L-LYSINE ANALOG USED AS A BIODEGRADABLE SOLUBLE GENE CONVEYOR
|
|
WO2000003660A1
(en)
*
|
1998-07-17 |
2000-01-27 |
Skyepharma, Inc. |
Biodegradable compositions for the controlled release of encapsulated substances
|
|
US6916490B1
(en)
*
|
1998-07-23 |
2005-07-12 |
UAB Research Center |
Controlled release of bioactive substances
|
|
US6610317B2
(en)
|
1999-05-27 |
2003-08-26 |
Acusphere, Inc. |
Porous paclitaxel matrices and methods of manufacture thereof
|
|
US6395300B1
(en)
*
|
1999-05-27 |
2002-05-28 |
Acusphere, Inc. |
Porous drug matrices and methods of manufacture thereof
|
|
US6521431B1
(en)
*
|
1999-06-22 |
2003-02-18 |
Access Pharmaceuticals, Inc. |
Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
|
|
EP1074248A1
(en)
*
|
1999-07-08 |
2001-02-07 |
Arnold Hilgers |
Delivery system for biological material
|
|
US6465425B1
(en)
|
2000-02-10 |
2002-10-15 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
|
|
US6284235B1
(en)
*
|
2000-02-11 |
2001-09-04 |
National Starch And Chemical Company Investment Holding Corporation |
Bioadhesive composition
|
|
AU2001244584B2
(en)
*
|
2000-03-31 |
2006-01-19 |
Kirin Pharma Kabushiki Kaisha |
Powdery preparation for transmucosal administration containing a polymeric form of drug and exhibiting improved storage stability
|
|
US6264987B1
(en)
*
|
2000-05-19 |
2001-07-24 |
Alkermes Controlled Therapeutics Inc. Ii |
Method for preparing microparticles having a selected polymer molecular weight
|
|
US6495164B1
(en)
|
2000-05-25 |
2002-12-17 |
Alkermes Controlled Therapeutics, Inc. I |
Preparation of injectable suspensions having improved injectability
|
|
US6362308B1
(en)
|
2000-08-10 |
2002-03-26 |
Alkermes Controlled Therapeutics Inc. Ii |
Acid end group poly(d,l-lactide-co-glycolide) copolymers high glycolide content
|
|
HK1052314A1
(zh)
*
|
2000-08-11 |
2003-09-11 |
Favrille, Inc. |
改变t细胞介导的病理的方法和组合物
|
|
US6911204B2
(en)
*
|
2000-08-11 |
2005-06-28 |
Favrille, Inc. |
Method and composition for altering a B cell mediated pathology
|
|
US6824822B2
(en)
*
|
2001-08-31 |
2004-11-30 |
Alkermes Controlled Therapeutics Inc. Ii |
Residual solvent extraction method and microparticles produced thereby
|
|
US6471995B1
(en)
|
2000-09-27 |
2002-10-29 |
Alkermes Controlled Therapeutics, Inc. Ii |
Apparatus and method for preparing microparticles using liquid-liquid extraction
|
|
ATE409465T1
(de)
|
2000-10-06 |
2008-10-15 |
Pacira Pharmaceuticals Inc |
Parenteral verabreichbare mikropartikel- zubereitung mit kontrollierter freisetzung
|
|
WO2002036169A2
(en)
|
2000-10-31 |
2002-05-10 |
Pr Pharmaceuticals, Inc. |
Methods and compositions for enhanced delivery of bioactive molecules
|
|
DE10055857A1
(de)
*
|
2000-11-10 |
2002-08-22 |
Creative Peptides Sweden Ab Dj |
Neue pharmazeutische Depotformulierung
|
|
US20040115277A1
(en)
*
|
2000-12-13 |
2004-06-17 |
Thomas Kissel |
Microparticles with an improved release profile and method for the production thereof
|
|
AU2001298061A1
(en)
|
2000-12-13 |
2003-07-09 |
Purdue Research Foundation |
Microencapsulation of drugs by solvent exchange
|
|
US20020114843A1
(en)
*
|
2000-12-27 |
2002-08-22 |
Ramstack J. Michael |
Preparation of microparticles having improved flowability
|
|
US6652886B2
(en)
*
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
|
CN1537018A
(zh)
|
2001-05-23 |
2004-10-13 |
田边制药株式会社 |
一种用于软骨疾病再生治疗的组合物
|
|
CN1520313A
(zh)
*
|
2001-05-23 |
2004-08-11 |
������ҩ��ʽ���� |
一种加速骨折愈合的组合物
|
|
US20030124149A1
(en)
*
|
2001-07-06 |
2003-07-03 |
Shalaby Shalaby W. |
Bioactive absorbable microparticles as therapeutic vaccines
|
|
US20030083286A1
(en)
*
|
2001-08-22 |
2003-05-01 |
Ching-Leou Teng |
Bioadhesive compositions and methods for enhanced intestinal drug absorption
|
|
US20030124196A1
(en)
*
|
2001-08-22 |
2003-07-03 |
Susan Weinbach |
Pulsatile release compositions and methods for enhanced intestinal drug absorption
|
|
CA2822457C
(en)
*
|
2001-12-14 |
2016-03-08 |
The University Of Wyoming |
Methods and compositions for controlled resease of drugs
|
|
EP1465596A1
(en)
*
|
2002-01-18 |
2004-10-13 |
Control Delivery Systems, Inc. |
Polymeric gel system for the controlled delivery of codrugs
|
|
US7635463B2
(en)
*
|
2002-02-27 |
2009-12-22 |
Pharmain Corporation |
Compositions for delivery of therapeutics and other materials
|
|
EP1478406B1
(en)
*
|
2002-02-27 |
2011-01-05 |
PharmaIN Corporation |
Compositions for delivery of therapeutics and other materials, and methods of making and using the same
|
|
KR100508911B1
(ko)
*
|
2002-05-09 |
2005-08-18 |
주식회사 펩트론 |
서방성 단백질 약물 제형 및 이의 제조방법
|
|
US7037983B2
(en)
|
2002-06-14 |
2006-05-02 |
Kimberly-Clark Worldwide, Inc. |
Methods of making functional biodegradable polymers
|
|
US20040001889A1
(en)
|
2002-06-25 |
2004-01-01 |
Guohua Chen |
Short duration depot formulations
|
|
AU2003284246A1
(en)
|
2002-10-16 |
2004-05-04 |
Samuel F. Hunter |
Method for treatment of demyelinating central nervous system disease using gm-csf
|
|
US7718189B2
(en)
|
2002-10-29 |
2010-05-18 |
Transave, Inc. |
Sustained release of antiinfectives
|
|
BRPI0409322B8
(pt)
|
2003-04-11 |
2021-05-25 |
Antriabio Inc |
método para preparar um conjugado de insulina-polímero
|
|
JP4763459B2
(ja)
*
|
2003-05-29 |
2011-08-31 |
株式会社東京大学Ｔｌｏ |
安定化高分子ミセル
|
|
GB0317999D0
(en)
*
|
2003-07-31 |
2003-09-03 |
Univ Liege |
Improvements in or relating to drug delivery systems
|
|
WO2005040199A1
(en)
*
|
2003-10-27 |
2005-05-06 |
Medvet Science Pty Ltd |
A bidentate motif and methods of use
|
|
EP1586334A1
(en)
*
|
2004-04-15 |
2005-10-19 |
TRASTEC scpa |
G-CSF conjugates with peg
|
|
CN1968700A
(zh)
|
2004-04-15 |
2007-05-23 |
阿尔克姆斯有限公司 |
聚合物基的持续释放装置
|
|
WO2005112977A2
(en)
*
|
2004-04-23 |
2005-12-01 |
Pharmain, Ltd. |
Compositions for treatment with glucagon-like peptide, and methods of making and using the same
|
|
EP1768700B1
(en)
*
|
2004-07-16 |
2010-12-15 |
Nektar Therapeutics |
Conjugates comprising gm-csf and a polymer
|
|
EP1674077A1
(en)
*
|
2004-12-27 |
2006-06-28 |
Université de Liège |
Mucoadhesive pharmaceutical compositions comprising chemoattractants
|
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
|
US9205046B2
(en)
*
|
2005-04-25 |
2015-12-08 |
The Governing Council Of The University Of Toronto |
Enhanced stability of inverse thermal gelling composite hydrogels
|
|
EP2099495A2
(en)
*
|
2005-08-04 |
2009-09-16 |
Nektar Therapeutics AL, Corporation |
Conjugates of a g-csf moiety and a polymer
|
|
US20070081972A1
(en)
*
|
2005-09-30 |
2007-04-12 |
The University Of Iowa Research Foundation |
Polymer-based delivery system for immunotherapy of cancer
|
|
US7585675B2
(en)
*
|
2005-11-15 |
2009-09-08 |
University Of Kansas Medical Center |
Inhibition of HIV and SHIV replication with antisense interleukin-4
|
|
DK1962805T3
(en)
|
2005-12-08 |
2016-09-26 |
Insmed Inc |
Lipid-based compositions of the anti-infective agents for the treatment of lung infections
|
|
AU2006330610B2
(en)
|
2005-12-19 |
2012-08-16 |
Pharmain Corporation |
Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same
|
|
ITMI20061545A1
(it)
*
|
2006-08-02 |
2008-02-03 |
Mediolanum Pharmaceuticals Ltd |
Particelle in grado di rilasciare il principio attivo per un periodo prolungato di tempo
|
|
KR101200728B1
(ko)
|
2006-08-09 |
2012-11-13 |
인타르시아 세라퓨틱스 인코포레이티드 |
삼투성 전달 시스템 및 피스톤 조립체
|
|
AU2008231093A1
(en)
*
|
2007-03-22 |
2008-10-02 |
Alkermes, Inc. |
Coacervation process
|
|
RU2440097C2
(ru)
|
2007-04-23 |
2012-01-20 |
Интарсия Терапьютикс, Инк. |
Способ лечения диабета ii типа и ожирения, осмотическое устройство для доставки и способ его изготовления
|
|
WO2008137717A1
(en)
|
2007-05-04 |
2008-11-13 |
Transave, Inc. |
Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
|
|
US9114081B2
(en)
|
2007-05-07 |
2015-08-25 |
Insmed Incorporated |
Methods of treating pulmonary disorders with liposomal amikacin formulations
|
|
US9119783B2
(en)
|
2007-05-07 |
2015-09-01 |
Insmed Incorporated |
Method of treating pulmonary disorders with liposomal amikacin formulations
|
|
US9333214B2
(en)
|
2007-05-07 |
2016-05-10 |
Insmed Incorporated |
Method for treating pulmonary disorders with liposomal amikacin formulations
|
|
US20080317865A1
(en)
*
|
2007-06-20 |
2008-12-25 |
Alkermes, Inc. |
Quench liquids and washing systems for production of microparticles
|
|
US7960336B2
(en)
*
|
2007-08-03 |
2011-06-14 |
Pharmain Corporation |
Composition for long-acting peptide analogs
|
|
US8563527B2
(en)
*
|
2007-08-20 |
2013-10-22 |
Pharmain Corporation |
Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same
|
|
US20090176892A1
(en)
|
2008-01-09 |
2009-07-09 |
Pharmain Corporation |
Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same
|
|
CA2726861C
(en)
|
2008-02-13 |
2014-05-27 |
Intarcia Therapeutics, Inc. |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
|
GB0814302D0
(en)
*
|
2008-08-05 |
2008-10-01 |
Coretherapix Slu |
Compounds and methods
|
|
CA2750003A1
(en)
*
|
2009-01-23 |
2010-07-29 |
Surmodics Pharmaceuticals, Inc. |
Controlled release systems from polymer blends
|
|
EP2396365A4
(en)
*
|
2009-02-11 |
2013-10-30 |
Univ Houston |
REDUCABLE POLYMERS FOR NONVIRAL GENEAL RELIEF
|
|
KR101233352B1
(ko)
*
|
2009-04-22 |
2013-02-25 |
(주)비씨월드제약 |
유전자 재조합 과립구-대식세포 집락 촉진인자를 함유하는 정제
|
|
EP2437879B1
(en)
*
|
2009-06-05 |
2017-07-26 |
Nanyang Technological University |
Multi-phase microparticles and method of manufacturing multi-phase microparticles
|
|
JP5376543B2
(ja)
|
2009-07-01 |
2013-12-25 |
独立行政法人科学技術振興機構 |
ポリイオンデンドリマー、及びそれよりなるハイドロゲル
|
|
HRP20171801T1
(hr)
|
2009-09-28 |
2017-12-29 |
Intarcia Therapeutics, Inc. |
Brzo uspostavljanje i/ili brzo završavanje uglavnom stabilne primjene lijeka
|
|
CA2780294C
(en)
|
2009-11-09 |
2018-01-16 |
Spotlight Technology Partners Llc |
Polysaccharide based hydrogels
|
|
CN107033368A
(zh)
|
2009-11-09 |
2017-08-11 |
聚光灯技术合伙有限责任公司 |
碎裂水凝胶
|
|
US8546353B2
(en)
|
2010-05-06 |
2013-10-01 |
Glykos Finland Oy |
Compounds and combinations
|
|
EP2384759A1
(en)
*
|
2010-05-06 |
2011-11-09 |
Suomen Punainen Risti Veripalvelu |
Sulphated hyaluronic acid in combination with G-CSF for use in mobilising blood stem cells
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
HRP20220158T1
(hr)
|
2012-05-21 |
2022-04-15 |
Insmed Incorporated |
Sustavi za liječenje plućnih infekcija
|
|
CA2891487A1
(en)
|
2012-11-29 |
2014-06-05 |
Insmed Incorporated |
Stabilized vancomycin formulations
|
|
EP3662924A1
(en)
*
|
2014-03-07 |
2020-06-10 |
Reponex Pharmaceuticals A/S |
Compositions for treating lung infections by airway administration
|
|
ES2926985T3
(es)
|
2014-05-15 |
2022-10-31 |
Insmed Inc |
Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas
|
|
US10105415B2
(en)
|
2014-07-24 |
2018-10-23 |
Reponex Pharmaceuticals A/S |
Compositions comprising granulocyte-macrophage colony-stimulating factor for the treatment of inflammatory bowel disease
|
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
|
CN113598842A
(zh)
|
2015-06-03 |
2021-11-05 |
因塔西亚制药公司 |
植入物放置和移除系统
|
|
RU2760007C2
(ru)
|
2016-05-16 |
2021-11-22 |
Интарсия Терапьютикс, Инк. |
Полипептиды, селективные к рецепторам глюкагона, и способы их применения
|
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
|
WO2018129058A1
(en)
|
2017-01-03 |
2018-07-12 |
Intarcia Therapeutics, Inc. |
Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
|
|
US11571386B2
(en)
|
2018-03-30 |
2023-02-07 |
Insmed Incorporated |
Methods for continuous manufacture of liposomal drug products
|
|
WO2020002650A1
(en)
*
|
2018-06-29 |
2020-01-02 |
Targovax Asa |
A formulation
|
|
JP7383264B2
(ja)
*
|
2018-09-28 |
2023-11-20 |
株式会社カネカ |
樹脂組成物およびその成形体
|
|
DE102019126672B4
(de)
*
|
2019-10-02 |
2021-07-01 |
Universität Rostock |
Wirkstoffdepotsystem sowie Kit zur in situ Polymerisation des Wirkstoffdepotsystems
|
|
BR112022013784A2
(pt)
|
2020-01-13 |
2022-10-11 |
Durect Corp |
Sistemas de distribuição de fármacos de liberação prolongada com impurezas reduzidas e métodos relacionados
|
|
JP2024503402A
(ja)
|
2021-01-12 |
2024-01-25 |
デュレクト コーポレーション |
徐放性薬物送達システム及び関連の方法
|
|
US11033495B1
(en)
|
2021-01-22 |
2021-06-15 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
|
US11278494B1
(en)
|
2021-01-22 |
2022-03-22 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
|
US11357727B1
(en)
|
2021-01-22 |
2022-06-14 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
|
US12151024B2
(en)
|
2021-01-22 |
2024-11-26 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
|
CN117979970A
(zh)
|
2021-10-14 |
2024-05-03 |
帕西拉制药有限公司 |
布比卡因多囊脂质体制剂及其用途
|
|
US12251472B1
(en)
|
2024-05-20 |
2025-03-18 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
|
US12251468B1
(en)
|
2024-05-20 |
2025-03-18 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
|
US12156940B1
(en)
|
2024-05-20 |
2024-12-03 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|