JPH11507017A5 - - Google Patents

Info

Publication number
JPH11507017A5
JPH11507017A5 JP1996534120A JP53412096A JPH11507017A5 JP H11507017 A5 JPH11507017 A5 JP H11507017A5 JP 1996534120 A JP1996534120 A JP 1996534120A JP 53412096 A JP53412096 A JP 53412096A JP H11507017 A5 JPH11507017 A5 JP H11507017A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1996534120A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11507017A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1996/006119 external-priority patent/WO1996035678A1/en
Publication of JPH11507017A publication Critical patent/JPH11507017A/ja
Publication of JPH11507017A5 publication Critical patent/JPH11507017A5/ja
Withdrawn legal-status Critical Current

Links

JP8534120A 1995-05-08 1996-05-03 ウイルス逆転写酵素の阻害剤としてのα−置換のピリミジン−チオアルキルおよびアルキルエーテル化合物 Withdrawn JPH11507017A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43670895A 1995-05-08 1995-05-08
US08/436,708 1995-05-08
PCT/US1996/006119 WO1996035678A1 (en) 1995-05-08 1996-05-03 Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase

Publications (2)

Publication Number Publication Date
JPH11507017A JPH11507017A (ja) 1999-06-22
JPH11507017A5 true JPH11507017A5 (OSRAM) 2004-07-08

Family

ID=23733510

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8534120A Withdrawn JPH11507017A (ja) 1995-05-08 1996-05-03 ウイルス逆転写酵素の阻害剤としてのα−置換のピリミジン−チオアルキルおよびアルキルエーテル化合物

Country Status (26)

Country Link
US (1) US6043248A (OSRAM)
EP (2) EP0824524B1 (OSRAM)
JP (1) JPH11507017A (OSRAM)
KR (1) KR100445498B1 (OSRAM)
CN (2) CN1152022C (OSRAM)
AT (1) ATE275550T1 (OSRAM)
AU (1) AU712404B2 (OSRAM)
BR (1) BR9608265A (OSRAM)
CA (1) CA2216099C (OSRAM)
CZ (1) CZ293135B6 (OSRAM)
DE (1) DE69633332T2 (OSRAM)
ES (1) ES2227586T3 (OSRAM)
GE (1) GEP20002297B (OSRAM)
HU (1) HUP9801995A3 (OSRAM)
IL (1) IL118075A0 (OSRAM)
MX (1) MX9708582A (OSRAM)
NO (1) NO310287B1 (OSRAM)
NZ (1) NZ307089A (OSRAM)
PL (1) PL323240A1 (OSRAM)
PT (1) PT824524E (OSRAM)
RU (1) RU2167155C2 (OSRAM)
SK (1) SK150297A3 (OSRAM)
TW (1) TW450962B (OSRAM)
UA (1) UA56992C2 (OSRAM)
WO (1) WO1996035678A1 (OSRAM)
ZA (1) ZA963281B (OSRAM)

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KR20010024271A (ko) * 1997-09-25 2001-03-26 로렌스 티. 마이젠헬더 티오알킬 알파 치환된 피리미딘 화합물
US6111111A (en) * 1997-10-23 2000-08-29 Kuraray Co., Ltd. Intermediates for producing pyridine derivatives
US7358254B2 (en) 2001-07-13 2008-04-15 Bristol-Myers Squibb Company Method for treating atherosclerosis employing an aP2 inhibitor and combination
EE200100155A (et) 1998-09-17 2002-08-15 Bristol-Myers Squibb Company Ateroskleroosi ravimeetod, kasutades aP2 inhibiitorit ja selle kombinatsiooni
JP2003503354A (ja) 1999-06-30 2003-01-28 メルク エンド カムパニー インコーポレーテッド Srcキナーゼ阻害剤化合物
US6498165B1 (en) 1999-06-30 2002-12-24 Merck & Co., Inc. Src kinase inhibitor compounds
WO2001000207A1 (en) 1999-06-30 2001-01-04 Merck & Co., Inc. Src kinase inhibitor compounds
US7138404B2 (en) * 2001-05-23 2006-11-21 Hoffmann-La Roche Inc. 4-aminopyrimidine derivatives
WO2006060711A2 (en) * 2004-12-03 2006-06-08 Merck & Co., Inc. Pharmaceutical formulation of carboxamide hiv integrase inhibitors containing a release rate controlling composition
ES2347815T3 (es) * 2005-03-04 2010-11-04 Tibotec Pharmaceuticals 2-(4-cianofenil)-6-hidroxilaminopirimidinas inhibidoras de hiv.
US7923056B2 (en) 2007-06-01 2011-04-12 Illinois Tool Works Inc. Method and apparatus for dispensing material on a substrate
TW201100411A (en) 2009-05-21 2011-01-01 Chlorion Pharma Inc Pyrimidines as novel therapeutic agents
CN101638391B (zh) * 2009-08-21 2011-04-27 山东大学 2-[(取代苯氨基)羰基甲硫基]-6-(2,6-二氯苄基)-3h-嘧啶-4-酮类衍生物及其制备方法与应用
US9226970B2 (en) 2010-02-22 2016-01-05 Nektar Therapeutics Oligomer modified diaromatic substituted compounds
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
EP2588450B1 (en) * 2010-07-02 2017-05-24 Gilead Sciences, Inc. Napht-2-ylacetic acid derivatives to treat aids
PL2691530T3 (pl) 2011-06-10 2019-02-28 Oregon Health & Science University Glikoproteiny i rekombinowane wektory CMV
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
EP2586461A1 (en) 2011-10-27 2013-05-01 Christopher L. Parks Viral particles derived from an enveloped virus
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
KR101360587B1 (ko) * 2012-11-01 2014-03-10 현대자동차주식회사 스마트 도어 언록 시스템
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
PL3324977T3 (pl) 2015-07-22 2022-11-14 Enanta Pharmaceuticals, Inc. Pochodne benzodiazepiny jako inhibitory rsv
GB201807898D0 (en) * 2018-05-15 2018-06-27 Kancera Ab New processes and products with increased chiral purity
WO2021066922A1 (en) * 2019-10-04 2021-04-08 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
EP4093198A4 (en) * 2020-01-20 2024-01-24 Agrematch Ltd. Compositions for crop protection
CN114057707A (zh) * 2021-11-24 2022-02-18 上海应用技术大学 一种n-4-吲哚基-2-呋喃甲酰胺化合物的制备方法
JP2025504415A (ja) * 2022-01-12 2025-02-12 アイエフエム デュー インコーポレイテッド Sting活性に関連する病態を治療するための化合物及び組成物

Family Cites Families (19)

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US2295560A (en) * 1941-06-18 1942-09-15 Gen Electric Pyrimidine derivatives
GB744867A (en) * 1952-10-29 1956-02-15 American Cyanamid Co Improvements relating to 2-substituted-mercapto-4-amino-6-disubstituted-aminopyrimidines and acid addition salts thereof
US3940394A (en) * 1972-03-31 1976-02-24 Santilli Arthur A 2-pyrimidinylthio)alkanoic acids, esters, amides and hydrazides
US3940240A (en) * 1974-07-11 1976-02-24 Ina Seito Co., Ltd. Baking method and kiln for tile
EP0124630B1 (de) * 1983-05-05 1987-01-28 LUDWIG HEUMANN & CO GMBH Pyrimidin-Thioalkylpyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindung enthaltende Arzneimittel
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
JPS62209062A (ja) * 1986-03-10 1987-09-14 Yamanouchi Pharmaceut Co Ltd 2−ピリジルメチルチオ−または2−ピリジルメチルスルフイニル−置換縮合環化合物
JPH07107056B2 (ja) * 1987-01-30 1995-11-15 日清製粉株式会社 4(3h)−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍剤
WO1989011279A1 (en) * 1988-05-16 1989-11-30 Georgia State University Foundation, Inc. Nucleic acid interacting unfused heteropolycyclic compounds
HU203736B (en) * 1989-04-06 1991-09-30 Gyogyszerkutato Intezet Process for producing new thiouracil-derivatives and pharmaceutical compositions containing them
WO1991009849A1 (en) * 1989-12-28 1991-07-11 The Upjohn Company Diaromatic substituted anti-aids compounds
US5668136A (en) * 1990-09-25 1997-09-16 Eisai Co., Ltd. Trisubstituted benzene derivatives, composition and methods of treatment
AU653855B2 (en) * 1991-07-03 1994-10-13 Pharmacia & Upjohn Company Indolyl carbonyl pyridinyl-poperazine/piperidine derivatives
GB2266716A (en) * 1992-05-05 1993-11-10 Merck & Co Inc Inhibitors of HIV reverse transcriptase
JP3077046B2 (ja) * 1992-08-31 2000-08-14 久光製薬株式会社 新規なキナゾリン誘導体
EP0720607A1 (en) * 1993-09-17 1996-07-10 PHARMACIA & UPJOHN COMPANY Substituted tetronic acids useful for treating hiv and other retroviruses
AU698625B2 (en) * 1993-11-12 1998-11-05 Pharmacia & Upjohn Company Pyrimidine-thioalkyl and alkylether compounds
US5945425A (en) * 1994-04-29 1999-08-31 G.D. Searle & Co. Method of using (H+ /K+)ATPase inhibitors as antiviral agents
PL318298A1 (en) * 1994-07-20 1997-06-09 Byk Gulden Lomberg Chem Fab Thiopyridil compounds for fighting against heliobacter

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