JP2000500145A5 - - Google Patents

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Publication number
JP2000500145A5
JP2000500145A5 JP1997518542A JP51854297A JP2000500145A5 JP 2000500145 A5 JP2000500145 A5 JP 2000500145A5 JP 1997518542 A JP1997518542 A JP 1997518542A JP 51854297 A JP51854297 A JP 51854297A JP 2000500145 A5 JP2000500145 A5 JP 2000500145A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997518542A
Other languages
English (en)
Japanese (ja)
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JP2000500145A (ja
JP4638560B2 (ja
Filing date
Publication date
Priority claimed from DE1995142189 external-priority patent/DE19542189A1/de
Priority claimed from DE1996112298 external-priority patent/DE19612298A1/de
Application filed filed Critical
Priority claimed from PCT/EP1996/004776 external-priority patent/WO1997018194A1/de
Publication of JP2000500145A publication Critical patent/JP2000500145A/ja
Publication of JP2000500145A5 publication Critical patent/JP2000500145A5/ja
Application granted granted Critical
Publication of JP4638560B2 publication Critical patent/JP4638560B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP51854297A 1995-11-13 1996-11-04 環式および複素環式のN−置換α−イミノヒドロキサム酸およびカルボン酸 Expired - Fee Related JP4638560B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19542189.2 1995-11-13
DE1995142189 DE19542189A1 (de) 1995-11-13 1995-11-13 Cyclische N-substituierte alpha-Iminohydroxamsäuren
DE1996112298 DE19612298A1 (de) 1996-03-28 1996-03-28 Heterocyclische N-substituierte alpha-Iminohydroxamsäuren
DE19612298.8 1996-03-28
PCT/EP1996/004776 WO1997018194A1 (de) 1995-11-13 1996-11-04 CYCLISCHE UND HETEROCYCLISCHE N-SUBSTITUIERTE α-IMINOHYDROXAM- UND CARBONSÄUREN

Publications (3)

Publication Number Publication Date
JP2000500145A JP2000500145A (ja) 2000-01-11
JP2000500145A5 true JP2000500145A5 (OSRAM) 2004-10-14
JP4638560B2 JP4638560B2 (ja) 2011-02-23

Family

ID=26020318

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51854297A Expired - Fee Related JP4638560B2 (ja) 1995-11-13 1996-11-04 環式および複素環式のN−置換α−イミノヒドロキサム酸およびカルボン酸

Country Status (20)

Country Link
US (3) US6207672B1 (OSRAM)
EP (1) EP0861236B2 (OSRAM)
JP (1) JP4638560B2 (OSRAM)
KR (1) KR100475206B1 (OSRAM)
CN (1) CN1131215C (OSRAM)
AT (1) ATE213232T1 (OSRAM)
AU (1) AU707707B2 (OSRAM)
BR (1) BR9611479B1 (OSRAM)
CA (1) CA2237590C (OSRAM)
CZ (1) CZ297550B6 (OSRAM)
DE (1) DE59608740D1 (OSRAM)
DK (1) DK0861236T4 (OSRAM)
ES (1) ES2170884T5 (OSRAM)
HU (1) HU223086B1 (OSRAM)
MX (1) MX9803753A (OSRAM)
PL (1) PL186869B1 (OSRAM)
PT (1) PT861236E (OSRAM)
RU (1) RU2164914C2 (OSRAM)
TR (1) TR199800849T2 (OSRAM)
WO (1) WO1997018194A1 (OSRAM)

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FR2771095B1 (fr) * 1997-11-14 1999-12-17 Adir Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6335329B1 (en) 1997-12-19 2002-01-01 Amgen Inc. Carboxylic acid substituted heterocycles, derivatives thereof and methods of use
US6107291A (en) * 1997-12-19 2000-08-22 Amgen Inc. Azepine or larger medium ring derivatives and methods of use
BR9907746A (pt) * 1998-01-27 2000-10-17 American Cyanamid Co ácidos 2,3,4,5-tetraidro-1h[1,4]-benzodiazepina-3-hidroxâmic os como inibidores de matriz de metaloproteinase
US6071903A (en) * 1998-01-27 2000-06-06 American Cyanamid Company 2,3,4,5-tetrahydro-1H-[1,4]-benzodiazepine-3-hydroxyamic acids
JP2002514647A (ja) 1998-05-14 2002-05-21 デュポン ファーマシューティカルズ カンパニー メタロプロテイナーゼ阻害薬としての新規な置換アリールヒドロキサム酸
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US20040122011A1 (en) * 1998-12-23 2004-06-24 Pharmacia Corporation Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
US6358980B1 (en) 1999-01-27 2002-03-19 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
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GB9903598D0 (en) * 1999-02-18 1999-04-07 Univ Manchester Connective tissue healing
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MXPA01013172A (es) 2001-02-14 2002-08-21 Warner Lambert Co Inhibidores sulfonamida de metaloproteinasa de matriz.
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WO2003016248A2 (en) 2001-08-17 2003-02-27 Bristol-Myers Squibb Company Patent Department Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or tnf-$g(a) converting enzyme (tace)
CN1610661A (zh) 2001-11-01 2005-04-27 惠氏控股公司 用作基质金属蛋白酶和tace的抑制剂的丙二烯芳基磺酰胺异羟肟酸
RU2223703C2 (ru) * 2002-02-13 2004-02-20 Иркутский государственный институт усовершенствования врачей Способ лечения передней хронической нестабильности коленного сустава
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