|
US5840294A
(en)
*
|
1993-03-29 |
1998-11-24 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
US20040208875A1
(en)
*
|
1995-03-15 |
2004-10-21 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
GB9610829D0
(en)
*
|
1996-05-23 |
1996-07-31 |
Medical Res Council |
Screening of agents for treatment of azlheimers disease
|
|
DK1014996T3
(da)
*
|
1997-08-28 |
2003-09-29 |
Univ Washington |
Præparater indeholdende saccharid til behandling af Alzheimers sygdom og andre amyloidoser
|
|
AU2006228064C1
(en)
*
|
1998-02-11 |
2009-01-29 |
Bhi Limited Partnership |
Method for modulating macrophage activation
|
|
DK1054664T3
(da)
*
|
1998-02-11 |
2012-11-05 |
Bhi Ltd Partnership |
Fremgangsmåde til modulering af makrofagaktivering
|
|
US20020022657A1
(en)
*
|
1998-02-11 |
2002-02-21 |
Francine Gervais |
Methods for modulating neuronal cell death
|
|
US6329356B1
(en)
|
1998-04-10 |
2001-12-11 |
Neurochem, Inc. |
Phosphono-carboxylate compounds for treating amyloidosis
|
|
IL139688A0
(en)
*
|
1998-05-15 |
2002-02-10 |
Neurochem Inc |
Use of amyloid inhibitors for modulating neuronal cell death
|
|
AU2006203051C1
(en)
*
|
1998-05-15 |
2009-01-22 |
Bhi Limited Partnership |
Use of amyloid inhibitors for modulating neuronal cell death
|
|
US6310073B1
(en)
*
|
1998-07-28 |
2001-10-30 |
Queen's University At Kingston |
Methods and compositions to treat glycosaminoglycan-associated molecular interactions
|
|
EP1609467A1
(en)
*
|
1998-07-28 |
2005-12-28 |
Neurochem (International) Limited |
Compositions for treating diseases associated with glycosaminoglycan-associated molecular interactions
|
|
CA2369997C
(en)
*
|
1999-04-28 |
2009-11-17 |
Queen's University At Kingston |
Compositions and methods for treating amyloidosis
|
|
AU2005203635B2
(en)
*
|
1999-05-24 |
2008-08-07 |
Bellus Health (International) Limited |
Methods and compounds for inhibiting amyloid deposits
|
|
US6562836B1
(en)
|
1999-05-24 |
2003-05-13 |
Queen's University Of Kingston |
Methods and compounds for inhibiting amyloid deposits
|
|
HK1051137A1
(zh)
*
|
1999-07-09 |
2003-07-25 |
Isis Innovation Limited |
抑制疾病的化合物和製備移植用的細胞
|
|
US6310048B1
(en)
|
1999-12-09 |
2001-10-30 |
St. Louis University |
Antisense modulation of amyloid beta protein expression
|
|
BR0016652A
(pt)
*
|
1999-12-23 |
2002-11-19 |
Neurochem Inc |
Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo
|
|
JP2005231998A
(ja)
*
|
2000-02-01 |
2005-09-02 |
Zeria Pharmaceut Co Ltd |
透析アミロイド線維重合核の製造方法及び透析アミロイド−シス治療剤のスクリーニング方法並びに透析アミロイドーシス治療剤
|
|
US20020115717A1
(en)
*
|
2000-07-25 |
2002-08-22 |
Francine Gervais |
Amyloid targeting imaging agents and uses thereof
|
|
US7311893B2
(en)
*
|
2000-07-25 |
2007-12-25 |
Neurochem (International) Limited |
Amyloid targeting imaging agents and uses thereof
|
|
US20070208087A1
(en)
|
2001-11-02 |
2007-09-06 |
Sanders Virginia J |
Compounds, compositions and methods for the treatment of inflammatory diseases
|
|
US20040006092A1
(en)
*
|
2001-08-31 |
2004-01-08 |
Neurochem, Inc. |
Amidine derivatives for treating amyloidosis
|
|
KR100994748B1
(ko)
|
2002-04-19 |
2010-11-17 |
더 가버닝 카운실 오브 더 유니버시티 오브 토론토 |
알쯔하이머병의 치료를 위한 면역학적 방법 및 조성물
|
|
PT1511710E
(pt)
*
|
2002-05-31 |
2014-02-26 |
Proteotech Inc |
Compostos, composições e métodos para o tratamento de doenças da amiloide e sinucleínopatias tais como doença de alzheimer, diabetes do tipo 2, e doença de parkinson
|
|
US20040057949A1
(en)
*
|
2002-09-23 |
2004-03-25 |
Depaolis Potito U. |
Hemodialysis method for improving immune system function
|
|
KR20050101537A
(ko)
*
|
2002-12-24 |
2005-10-24 |
뉴로켐 (인터내셔널) 리미티드 |
베타-아밀로이드 관련 질환의 치료를 위한 치료 제제
|
|
US20050031651A1
(en)
*
|
2002-12-24 |
2005-02-10 |
Francine Gervais |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7521481B2
(en)
*
|
2003-02-27 |
2009-04-21 |
Mclaurin Joanne |
Methods of preventing, treating and diagnosing disorders of protein aggregation
|
|
CN1805743A
(zh)
*
|
2003-05-20 |
2006-07-19 |
特兰斯泰克制药公司 |
用作逆转淀粉样变性及其他与之相关疾病的rage拮抗剂
|
|
US20060079578A1
(en)
*
|
2003-06-23 |
2006-04-13 |
Julie Laurin |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
US7253306B2
(en)
|
2003-06-23 |
2007-08-07 |
Neurochem (International) Limited |
Pharmaceutical drug candidates and methods for preparation thereof
|
|
US20050142191A1
(en)
*
|
2003-06-23 |
2005-06-30 |
Neurochem (International) Limited |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
US20070010573A1
(en)
*
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
|
EP1646659B1
(en)
*
|
2003-06-23 |
2014-05-14 |
Kiacta Sàrl |
Method for the preparation of 1,3-propane disulfonic acid compounds
|
|
HRP20140442T1
(hr)
*
|
2003-06-23 |
2014-07-04 |
Kiacta Sàrl |
Metoda za pripremu spoja 1,3-propan disulfonske kiseline
|
|
AU2004249529A1
(en)
*
|
2003-06-23 |
2004-12-29 |
Bellus Health (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US7244764B2
(en)
*
|
2003-06-23 |
2007-07-17 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US7414076B2
(en)
*
|
2003-06-23 |
2008-08-19 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
AU2011250847B2
(en)
*
|
2003-06-23 |
2013-06-20 |
Bhi Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
MXPA05013692A
(es)
*
|
2003-06-23 |
2006-03-13 |
Neurochem Int Ltd |
Metodos para tratar trastornos por acumulacion de proteina.
|
|
US7262223B2
(en)
*
|
2004-01-23 |
2007-08-28 |
Neurochem (International) Limited |
Amidine derivatives for treating amyloidosis
|
|
JP4753022B2
(ja)
*
|
2004-02-17 |
2011-08-17 |
独立行政法人産業技術総合研究所 |
プリオン増殖抑制剤
|
|
CA2560618A1
(en)
*
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
AU2005310986A1
(en)
*
|
2004-11-12 |
2006-06-08 |
Bellus Health (International) Limited |
Methods and fluorinated compositions for treating amyloid-related diseases
|
|
AU2005310979A1
(en)
*
|
2004-11-16 |
2006-06-08 |
Bellus Health (International) Limited |
Compounds for the treatment of CNS and amyloid associated diseases
|
|
EP2186518A1
(en)
*
|
2004-11-17 |
2010-05-19 |
McLaurin, Joanne |
Composition and methods for treatment of disorders of protein aggregation
|
|
EP1836161B1
(en)
*
|
2004-12-22 |
2016-07-20 |
BHI Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
US20060251714A1
(en)
*
|
2005-04-12 |
2006-11-09 |
Julie Laurin |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
TW200716088A
(en)
*
|
2005-04-15 |
2007-05-01 |
Neurochem Int Ltd |
Formulations and methods for treating amyloidosis
|
|
JP2008545663A
(ja)
*
|
2005-05-27 |
2008-12-18 |
クイーンズ ユニバーシティ アット キングストン |
タンパク質フォールディング障害の治療
|
|
WO2007023389A2
(en)
*
|
2005-07-21 |
2007-03-01 |
Neurochem (International) Limited |
Polymorphic forms of 3-amino-1-propanesulfonic acid
|
|
AU2006321294A1
(en)
*
|
2005-09-30 |
2007-06-07 |
Bellus Health (International) Limited |
Pharmaceutical compositions comprising carboxyalkylsulfonic acids
|
|
WO2007041855A1
(en)
*
|
2005-10-13 |
2007-04-19 |
Waratah Pharmaceuticals, Inc. |
Scyllo-inositol derivatives and their use in the treatment of diseases characterised by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
|
|
PL1976877T5
(pl)
|
2005-11-30 |
2017-09-29 |
Abbvie Inc |
Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania
|
|
RU2442793C2
(ru)
|
2005-11-30 |
2012-02-20 |
Эбботт Лэборетриз |
АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ
|
|
ATE481094T1
(de)
*
|
2005-12-22 |
2010-10-15 |
Kiacta Sarl |
Behandlung von diabetischer nephropathie
|
|
US20100048713A1
(en)
*
|
2006-01-06 |
2010-02-25 |
Aarhus Universitet |
Compounds acting on the serotonin transporter
|
|
US20070197452A1
(en)
*
|
2006-02-17 |
2007-08-23 |
Mclaurin Joanne |
Treatment of amyloid-related diseases
|
|
WO2007101353A1
(en)
*
|
2006-03-09 |
2007-09-13 |
Waratah Pharmaceuticals Inc. |
A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation
|
|
US20110028719A1
(en)
*
|
2006-05-19 |
2011-02-03 |
Jacek Slon-Usakiewicz |
Screening methods for amyloid beta modulators
|
|
US20100173960A1
(en)
*
|
2006-09-21 |
2010-07-08 |
Antonio Cruz |
The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
|
|
SI2089417T1
(sl)
*
|
2006-10-12 |
2015-04-30 |
Bhi Limited Partnership |
Metode, spojine, sestavki in vektorji za dostavo 3-amino-1-propansulfonske kisline
|
|
US20100292157A1
(en)
*
|
2006-11-24 |
2010-11-18 |
Antonio Cruz |
Combination Treatments for Alzheimer's Disease and Similar Diseases
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
JP2010513219A
(ja)
*
|
2006-12-22 |
2010-04-30 |
ベラス ヘルス （インターナショナル） リミテッド |
腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療
|
|
CA2673022A1
(en)
*
|
2006-12-22 |
2008-07-03 |
Bellus Health (International) Limited |
Methods, compounds, and compositions for treating metabolic disorders and diabetes
|
|
US8895004B2
(en)
|
2007-02-27 |
2014-11-25 |
AbbVie Deutschland GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
AR060412A1
(es)
*
|
2007-04-10 |
2008-06-18 |
Creactivar S A |
Una composicion farmaceutica utilizable para inhibir o evitar la formacion no deseada de tejido fibroso y uso de la n- sulfoetilnicotinamida para inhibir o evitar la formacion no deseada de tejido fibroso
|
|
AR060411A1
(es)
*
|
2007-04-10 |
2008-06-18 |
Creactivar S A |
Una composicion farmaceutica utilizable en el tratamiento o prevencion de una enfermedad pulmonar y uso de la n-sulfoetilnicotinamida en el tratamiento o prevencion de dicha enfermedad
|
|
CA2683546A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives in the treatment of .alpha.-synucleinopathies
|
|
US20110105626A1
(en)
*
|
2007-04-12 |
2011-05-05 |
Mclaurin Joanne |
Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
|
|
EP2148667B1
(en)
*
|
2007-04-12 |
2013-05-22 |
Waratah Pharmaceuticals, Inc. |
Use of cyclohexanehexol derivatives in the treatment of ocular diseases
|
|
WO2008124931A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis
|
|
US8613923B2
(en)
|
2007-06-12 |
2013-12-24 |
Ac Immune S.A. |
Monoclonal antibody
|
|
US8048420B2
(en)
|
2007-06-12 |
2011-11-01 |
Ac Immune S.A. |
Monoclonal antibody
|
|
PL2238166T3
(pl)
|
2007-10-05 |
2014-07-31 |
Genentech Inc |
Zastosowanie przeciwciała anty-Beta amyloidowego w chorobach oczu
|
|
EP2349233A4
(en)
*
|
2008-10-09 |
2012-04-18 |
Waratah Pharmaceuticals Inc |
USE OF SCYLLO-INOSITOLS FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH MACULAR DEGENERATION
|
|
CN102471248B
(zh)
*
|
2009-08-10 |
2015-01-07 |
Bhi有限合伙公司 |
用于递送1,3-丙二磺酸的方法、化合物和组合物
|
|
CA2774375C
(en)
*
|
2009-09-17 |
2018-02-13 |
Bespoke Bioscience, Llc |
Role of n-2 hydroxy-ethyl-piperazine-n'-2-ethane sulfonic acid (hepes) in pain control and reversal of demyelinization injury
|
|
CA2772797C
(en)
|
2009-09-30 |
2018-09-25 |
Transtech Pharma, Inc. |
Substituted imidazole derivatives
|
|
KR101173677B1
(ko)
*
|
2009-12-11 |
2012-08-13 |
한국과학기술연구원 |
Ｅｐｐｓ를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물
|
|
WO2011130377A2
(en)
|
2010-04-15 |
2011-10-20 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
|
US9221900B2
(en)
|
2010-07-30 |
2015-12-29 |
Ac Immune S.A. |
Methods for identifying safe and functional humanized antibodies
|
|
US9062101B2
(en)
|
2010-08-14 |
2015-06-23 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
|
KR20150064743A
(ko)
|
2012-10-05 |
2015-06-11 |
트랜스테크 파르마 엘엘씨 |
경도 및 중등도 알츠하이머 병의 치료
|
|
CA3054370A1
(en)
|
2017-02-24 |
2018-08-30 |
Alzheon, Inc. |
Methods for treating neurodegenerative disorders
|
|
CN114805211B
(zh)
|
2017-03-21 |
2024-08-23 |
润佳（苏州）医药科技有限公司 |
同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途
|
|
CN109394746A
(zh)
*
|
2017-08-15 |
2019-03-01 |
江西青峰药业有限公司 |
乙基硫酸铵在制备用于预防或治疗炎症性疾病药物中的应用
|
|
WO2019190822A1
(en)
|
2018-03-28 |
2019-10-03 |
Vtv Therapeutics Llc |
Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
|
|
WO2019190823A1
(en)
|
2018-03-28 |
2019-10-03 |
Vtv Therapeutics Llc |
Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
|
|
SI4296670T1
(sl)
*
|
2018-08-01 |
2026-04-30 |
Alzheon, Inc. |
Derivati sulfopropanojske kisline za zdravljenje nevrodegenerativnih motenj
|
|
MX2021001287A
(es)
*
|
2018-08-01 |
2021-07-15 |
Alzheon Inc |
Métodos para tratar trastornos neurodegenerativos.
|
|
JP7464591B2
(ja)
|
2018-10-10 |
2024-04-09 |
ブイティーブイ・セラピューティクス・エルエルシー |
［３－（４－｛２－ブチル－１－［４－（４－クロロ－フェノキシ）－フェニル］－１ｈ－イミダゾール－４－イル｝－フェノキシ）－プロピル］－ジエチル－アミンの代謝産物
|
|
CN112791078B
(zh)
|
2019-11-13 |
2022-12-06 |
润佳（苏州）医药科技有限公司 |
同位素富集的3-氨基-1-丙磺酸及其衍生物的用途
|