|
US20040208875A1
(en)
*
|
1995-03-15 |
2004-10-21 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
US5840294A
(en)
*
|
1993-03-29 |
1998-11-24 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
GB9610829D0
(en)
*
|
1996-05-23 |
1996-07-31 |
Medical Res Council |
Screening of agents for treatment of azlheimers disease
|
|
EP1014996B1
(en)
*
|
1997-08-28 |
2003-05-28 |
University of Washington |
Saccharide-containing compositions for treating alzheimer's disease and other amyloidoses
|
|
MXPA00007815A
(es)
*
|
1998-02-11 |
2002-04-24 |
Neurochem Inc |
Metodo para modular la activacion de macrofagos.
|
|
US20020022657A1
(en)
*
|
1998-02-11 |
2002-02-21 |
Francine Gervais |
Methods for modulating neuronal cell death
|
|
AU2006228064C1
(en)
*
|
1998-02-11 |
2009-01-29 |
Bhi Limited Partnership |
Method for modulating macrophage activation
|
|
US6329356B1
(en)
|
1998-04-10 |
2001-12-11 |
Neurochem, Inc. |
Phosphono-carboxylate compounds for treating amyloidosis
|
|
AU2006203051C1
(en)
*
|
1998-05-15 |
2009-01-22 |
Bhi Limited Partnership |
Use of amyloid inhibitors for modulating neuronal cell death
|
|
WO1999059571A1
(en)
*
|
1998-05-15 |
1999-11-25 |
Neurochem, Inc. |
Use of amyloid inhibitors for modulating neuronal cell death
|
|
EP1609467A1
(en)
*
|
1998-07-28 |
2005-12-28 |
Neurochem (International) Limited |
Compositions for treating diseases associated with glycosaminoglycan-associated molecular interactions
|
|
US6310073B1
(en)
*
|
1998-07-28 |
2001-10-30 |
Queen's University At Kingston |
Methods and compositions to treat glycosaminoglycan-associated molecular interactions
|
|
NZ543319A
(en)
*
|
1999-04-28 |
2007-06-29 |
Neurochem Int Ltd |
Compositions and methods for treating amyloidosis using sulphonate derivatives
|
|
US6562836B1
(en)
*
|
1999-05-24 |
2003-05-13 |
Queen's University Of Kingston |
Methods and compounds for inhibiting amyloid deposits
|
|
AU2005203635B2
(en)
*
|
1999-05-24 |
2008-08-07 |
Bellus Health (International) Limited |
Methods and compounds for inhibiting amyloid deposits
|
|
AU5994900A
(en)
*
|
1999-07-09 |
2001-01-30 |
Isis Innovation Limited |
Compounds for inhibiting diseases and preparing cells for transplantation
|
|
US6310048B1
(en)
|
1999-12-09 |
2001-10-30 |
St. Louis University |
Antisense modulation of amyloid beta protein expression
|
|
WO2001085093A2
(en)
|
1999-12-23 |
2001-11-15 |
Neurochem, Inc. |
Compounds and methods for modulating cerebral amyloid angiopathy
|
|
JP2005231998A
(ja)
*
|
2000-02-01 |
2005-09-02 |
Zeria Pharmaceut Co Ltd |
透析アミロイド線維重合核の製造方法及び透析アミロイド−シス治療剤のスクリーニング方法並びに透析アミロイドーシス治療剤
|
|
US7311893B2
(en)
*
|
2000-07-25 |
2007-12-25 |
Neurochem (International) Limited |
Amyloid targeting imaging agents and uses thereof
|
|
US20020115717A1
(en)
*
|
2000-07-25 |
2002-08-22 |
Francine Gervais |
Amyloid targeting imaging agents and uses thereof
|
|
US20070208087A1
(en)
|
2001-11-02 |
2007-09-06 |
Sanders Virginia J |
Compounds, compositions and methods for the treatment of inflammatory diseases
|
|
MXPA04001153A
(es)
*
|
2001-08-31 |
2005-02-17 |
Neurochem Int Ltd |
Derivados de amidina para tratar la amiloidosis.
|
|
CN100360555C
(zh)
|
2002-04-19 |
2008-01-09 |
多伦多大学董事局 |
治疗阿尔茨海默氏病的免疫学方法及组合物
|
|
WO2003101927A1
(en)
|
2002-05-31 |
2003-12-11 |
Proteotech, Inc. |
Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease
|
|
US20040057949A1
(en)
*
|
2002-09-23 |
2004-03-25 |
Depaolis Potito U. |
Hemodialysis method for improving immune system function
|
|
US20050031651A1
(en)
*
|
2002-12-24 |
2005-02-10 |
Francine Gervais |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
WO2004058239A1
(en)
*
|
2002-12-24 |
2004-07-15 |
Neurochem (International) Limited |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7521481B2
(en)
|
2003-02-27 |
2009-04-21 |
Mclaurin Joanne |
Methods of preventing, treating and diagnosing disorders of protein aggregation
|
|
CN1805743A
(zh)
*
|
2003-05-20 |
2006-07-19 |
特兰斯泰克制药公司 |
用作逆转淀粉样变性及其他与之相关疾病的rage拮抗剂
|
|
US20050142191A1
(en)
*
|
2003-06-23 |
2005-06-30 |
Neurochem (International) Limited |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
SI1646659T1
(sl)
*
|
2003-06-23 |
2014-07-31 |
Kiacta Sarl |
Postopek za pripravo spojin 1,3-propan disulfonske kisline
|
|
MXPA05013607A
(es)
*
|
2003-06-23 |
2006-04-06 |
Neurochem Int Ltd |
Candidatos de farmaco farmaceuticos mejorados y metodos para preparar los mismos.
|
|
US20060079578A1
(en)
*
|
2003-06-23 |
2006-04-13 |
Julie Laurin |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
US7414076B2
(en)
*
|
2003-06-23 |
2008-08-19 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US7253306B2
(en)
|
2003-06-23 |
2007-08-07 |
Neurochem (International) Limited |
Pharmaceutical drug candidates and methods for preparation thereof
|
|
AU2011250847B2
(en)
*
|
2003-06-23 |
2013-06-20 |
Bhi Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
WO2005000288A2
(en)
*
|
2003-06-23 |
2005-01-06 |
Neurochem (International) Limited |
Treatment of protein aggregation disorders
|
|
EP1658264A2
(en)
*
|
2003-06-23 |
2006-05-24 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US20070010573A1
(en)
*
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
|
US7244764B2
(en)
|
2003-06-23 |
2007-07-17 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US7262223B2
(en)
*
|
2004-01-23 |
2007-08-28 |
Neurochem (International) Limited |
Amidine derivatives for treating amyloidosis
|
|
JP4753022B2
(ja)
*
|
2004-02-17 |
2011-08-17 |
独立行政法人産業技術総合研究所 |
プリオン増殖抑制剤
|
|
US20050267029A1
(en)
*
|
2004-04-02 |
2005-12-01 |
Ancsin John B |
Compounds which modulate amyloidogenesis and methods for their identification and use
|
|
BRPI0517790A
(pt)
*
|
2004-11-12 |
2008-10-21 |
Neurochem Int Ltd |
métodos e composições fluoradas para tratar doenças relacionadas à amilóide
|
|
CA2586334A1
(en)
*
|
2004-11-16 |
2006-06-08 |
Neurochem (International) Limited |
Compounds for the treatment of cns and amyloid associated diseases
|
|
US20060189582A1
(en)
*
|
2004-11-17 |
2006-08-24 |
Mclaurin Joanne |
Compositions and methods for treatment of disorders of protein aggregation
|
|
WO2006085149A2
(en)
|
2004-12-22 |
2006-08-17 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US20060257480A1
(en)
*
|
2005-04-12 |
2006-11-16 |
Julie Laurin |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
TW200716088A
(en)
|
2005-04-15 |
2007-05-01 |
Neurochem Int Ltd |
Formulations and methods for treating amyloidosis
|
|
EP1893576A4
(en)
*
|
2005-05-27 |
2010-03-17 |
Univ Kingston |
TREATMENT OF PROTEIN DISORDERING
|
|
US20070049638A1
(en)
*
|
2005-07-21 |
2007-03-01 |
Neurochem (International) Limited |
Polymorphic forms of 3-amino-1-propanesulfonic acid
|
|
CA2624693A1
(en)
*
|
2005-09-30 |
2007-06-07 |
Neurochem (International) Limited |
Pharmaceutical compositions comprising carboxyalkylsulfonic acids
|
|
WO2007119108A2
(en)
*
|
2005-10-13 |
2007-10-25 |
Waratah Pharmaceuticals Inc. |
Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
|
|
BRPI0619249A2
(pt)
|
2005-11-30 |
2011-09-20 |
Abbott Lab |
anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
|
|
PT1976877E
(pt)
|
2005-11-30 |
2014-04-29 |
Abbvie Inc |
Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações
|
|
MX2008008213A
(es)
*
|
2005-12-22 |
2008-09-03 |
Neurochem Int Ltd |
Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias.
|
|
EP1976495A2
(en)
*
|
2006-01-06 |
2008-10-08 |
Aarhus Universitet |
Compounds acting on the serotonin transporter
|
|
US20070197452A1
(en)
*
|
2006-02-17 |
2007-08-23 |
Mclaurin Joanne |
Treatment of amyloid-related diseases
|
|
EP1996175A4
(en)
*
|
2006-03-09 |
2009-06-10 |
Waratah Pharmaceuticals Inc |
CYCLOHEXAN POLYALKOHOL FORMULATION FOR THE TREATMENT OF PROTEIN AGGREGATION DISORDERS
|
|
CA2652449A1
(en)
*
|
2006-05-19 |
2007-11-29 |
Waratah Pharmaceuticals Inc. |
Screening methods for amyloid beta modulators
|
|
WO2008034244A1
(en)
*
|
2006-09-21 |
2008-03-27 |
Waratah Pharmaceuticals Inc. |
The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases
|
|
KR101608445B1
(ko)
*
|
2006-10-12 |
2016-04-01 |
비에이치아이 리미티드 파트너쉽 |
3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클
|
|
WO2008061373A1
(en)
*
|
2006-11-24 |
2008-05-29 |
Waratah Pharmaceuticals Inc. |
Combination treatments for alzheimer's disease and similar diseases
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
EP2120905A1
(en)
*
|
2006-12-22 |
2009-11-25 |
BELLUS Health (International) Limited |
Methods, compounds, and compositions for treating metabolic disorders and diabetes
|
|
JP2010513219A
(ja)
*
|
2006-12-22 |
2010-04-30 |
ベラス ヘルス （インターナショナル） リミテッド |
腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
AR060412A1
(es)
*
|
2007-04-10 |
2008-06-18 |
Creactivar S A |
Una composicion farmaceutica utilizable para inhibir o evitar la formacion no deseada de tejido fibroso y uso de la n- sulfoetilnicotinamida para inhibir o evitar la formacion no deseada de tejido fibroso
|
|
AR060411A1
(es)
*
|
2007-04-10 |
2008-06-18 |
Creactivar S A |
Una composicion farmaceutica utilizable en el tratamiento o prevencion de una enfermedad pulmonar y uso de la n-sulfoetilnicotinamida en el tratamiento o prevencion de dicha enfermedad
|
|
WO2008124931A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis
|
|
US20100331267A1
(en)
*
|
2007-04-12 |
2010-12-30 |
Mclaurin Joanne |
Use of cyclohexanehexol derivatives in the treatment of alpha-synucleinopathies
|
|
EP2148667B1
(en)
*
|
2007-04-12 |
2013-05-22 |
Waratah Pharmaceuticals, Inc. |
Use of cyclohexanehexol derivatives in the treatment of ocular diseases
|
|
CA2683548A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
|
|
US8613923B2
(en)
|
2007-06-12 |
2013-12-24 |
Ac Immune S.A. |
Monoclonal antibody
|
|
US8048420B2
(en)
|
2007-06-12 |
2011-11-01 |
Ac Immune S.A. |
Monoclonal antibody
|
|
EP2586795B1
(en)
|
2007-10-05 |
2018-05-16 |
Genentech, Inc. |
Use of anti-amyloid beta antibody in ocular diseases
|
|
JP2012505162A
(ja)
*
|
2008-10-09 |
2012-03-01 |
ワラタ ファーマシューティカルズ， インコーポレイテッド |
黄斑変性症関連障害を処置するためのｓｃｙｌｌｏ−イノシトールの使用
|
|
EA201290007A1
(ru)
*
|
2009-08-10 |
2013-01-30 |
Беллус Хелс Инк. |
Способы, соединения и композиции для доставки 1,3-пропандисульфокислоты
|
|
CN107260740A
(zh)
*
|
2009-09-17 |
2017-10-20 |
比斯普科生物科学有限公司 |
N‑2‑羟基‑乙基‑哌嗪‑n’‑2‑乙磺酸(hepes) 在疼痛控制和脱髓鞘损伤逆转中的作用
|
|
CA2772797C
(en)
|
2009-09-30 |
2018-09-25 |
Transtech Pharma, Inc. |
Substituted imidazole derivatives
|
|
KR101173677B1
(ko)
*
|
2009-12-11 |
2012-08-13 |
한국과학기술연구원 |
Ｅｐｐｓ를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물
|
|
EP2558494B1
(en)
|
2010-04-15 |
2018-05-23 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
|
AU2011282536B2
(en)
|
2010-07-30 |
2015-12-24 |
Ac Immune S.A. |
Safe and functional humanized anti beta-amyloid antibody
|
|
CN105348387B
(zh)
|
2010-08-14 |
2020-08-25 |
Abbvie 公司 |
β淀粉样蛋白结合蛋白
|
|
US9717710B2
(en)
|
2012-10-05 |
2017-08-01 |
Vtv Therapeutics Llc |
Treatment of mild and moderate Alzheimer's disease
|
|
US11077095B2
(en)
|
2017-02-24 |
2021-08-03 |
Alzheon, Inc. |
Methods for treating neurodegenerative disorders
|
|
CN114805211B
(zh)
|
2017-03-21 |
2024-08-23 |
润佳（苏州）医药科技有限公司 |
同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途
|
|
CN109394746A
(zh)
*
|
2017-08-15 |
2019-03-01 |
江西青峰药业有限公司 |
乙基硫酸铵在制备用于预防或治疗炎症性疾病药物中的应用
|
|
WO2019190823A1
(en)
|
2018-03-28 |
2019-10-03 |
Vtv Therapeutics Llc |
Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
|
|
WO2019190822A1
(en)
|
2018-03-28 |
2019-10-03 |
Vtv Therapeutics Llc |
Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
|
|
AU2019314323B2
(en)
*
|
2018-08-01 |
2025-05-01 |
Alzheon, Inc. |
Sulfopropanoic acid derivatives for treating neurodegenerative disorders
|
|
DK3829563T3
(en)
|
2018-08-01 |
2025-02-24 |
Alzheon Inc |
3-sulfopropanoic acid for treating neurodegenerative disorders
|
|
JP7464591B2
(ja)
|
2018-10-10 |
2024-04-09 |
ブイティーブイ・セラピューティクス・エルエルシー |
［３－（４－｛２－ブチル－１－［４－（４－クロロ－フェノキシ）－フェニル］－１ｈ－イミダゾール－４－イル｝－フェノキシ）－プロピル］－ジエチル－アミンの代謝産物
|
|
CN116059192B
(zh)
|
2019-11-13 |
2024-10-29 |
润佳（苏州）医药科技有限公司 |
同位素富集的3-氨基-1-丙磺酸及其衍生物的用途
|