|
US20040208875A1
(en)
*
|
1995-03-15 |
2004-10-21 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
US5840294A
(en)
*
|
1993-03-29 |
1998-11-24 |
Queen's University At Kingston |
Method for treating amyloidosis
|
|
GB9610829D0
(en)
*
|
1996-05-23 |
1996-07-31 |
Medical Res Council |
Screening of agents for treatment of azlheimers disease
|
|
ES2200366T3
(es)
*
|
1997-08-28 |
2004-03-01 |
University Of Washington |
Composiciones de sacaridos para el tratamiento de la enfermedad de alzheimer y otras amiloidoisis.
|
|
US20020022657A1
(en)
*
|
1998-02-11 |
2002-02-21 |
Francine Gervais |
Methods for modulating neuronal cell death
|
|
MX2008014823A
(es)
*
|
1998-02-11 |
2009-03-06 |
Neurochem Int Ltd |
Metodo para modular la activacion de macrofagos.
|
|
AU2006228064C1
(en)
*
|
1998-02-11 |
2009-01-29 |
Bhi Limited Partnership |
Method for modulating macrophage activation
|
|
US6329356B1
(en)
|
1998-04-10 |
2001-12-11 |
Neurochem, Inc. |
Phosphono-carboxylate compounds for treating amyloidosis
|
|
WO1999059571A1
(en)
*
|
1998-05-15 |
1999-11-25 |
Neurochem, Inc. |
Use of amyloid inhibitors for modulating neuronal cell death
|
|
AU2006203051C1
(en)
*
|
1998-05-15 |
2009-01-22 |
Bhi Limited Partnership |
Use of amyloid inhibitors for modulating neuronal cell death
|
|
EP1609467A1
(en)
*
|
1998-07-28 |
2005-12-28 |
Neurochem (International) Limited |
Compositions for treating diseases associated with glycosaminoglycan-associated molecular interactions
|
|
US6310073B1
(en)
*
|
1998-07-28 |
2001-10-30 |
Queen's University At Kingston |
Methods and compositions to treat glycosaminoglycan-associated molecular interactions
|
|
AU4282400A
(en)
*
|
1999-04-28 |
2000-11-10 |
Neurochem (International) Limited |
Compositions and methods for treating amyloidosis
|
|
AU2005203635B2
(en)
*
|
1999-05-24 |
2008-08-07 |
Bellus Health (International) Limited |
Methods and compounds for inhibiting amyloid deposits
|
|
US6562836B1
(en)
|
1999-05-24 |
2003-05-13 |
Queen's University Of Kingston |
Methods and compounds for inhibiting amyloid deposits
|
|
HK1051137A1
(zh)
*
|
1999-07-09 |
2003-07-25 |
Isis Innovation Limited |
抑制疾病的化合物和製備移植用的細胞
|
|
US6310048B1
(en)
|
1999-12-09 |
2001-10-30 |
St. Louis University |
Antisense modulation of amyloid beta protein expression
|
|
WO2001085093A2
(en)
*
|
1999-12-23 |
2001-11-15 |
Neurochem, Inc. |
Compounds and methods for modulating cerebral amyloid angiopathy
|
|
JP2005231998A
(ja)
*
|
2000-02-01 |
2005-09-02 |
Zeria Pharmaceut Co Ltd |
透析アミロイド線維重合核の製造方法及び透析アミロイド−シス治療剤のスクリーニング方法並びに透析アミロイドーシス治療剤
|
|
US20020115717A1
(en)
*
|
2000-07-25 |
2002-08-22 |
Francine Gervais |
Amyloid targeting imaging agents and uses thereof
|
|
US7311893B2
(en)
*
|
2000-07-25 |
2007-12-25 |
Neurochem (International) Limited |
Amyloid targeting imaging agents and uses thereof
|
|
US20070208087A1
(en)
|
2001-11-02 |
2007-09-06 |
Sanders Virginia J |
Compounds, compositions and methods for the treatment of inflammatory diseases
|
|
CA2455497A1
(en)
*
|
2001-08-31 |
2003-03-06 |
Neurochem (International) Limited |
Amidine derivatives for treating amyloidosis
|
|
AU2003218560B2
(en)
|
2002-04-19 |
2009-09-03 |
The Governing Council Of The University Of Toronto |
Immunological methods and compositions for the treatment of alzheimer's disease
|
|
DK2527315T3
(da)
|
2002-05-31 |
2014-06-02 |
Proteotech Inc |
Forbindelser, præparater og fremgangsmåder til behandling af amyloide sygdomme og synukleinopatier, såsom Alzheimers sygdom, type 2-diabetes og Parkinsons sygdom
|
|
US20040057949A1
(en)
*
|
2002-09-23 |
2004-03-25 |
Depaolis Potito U. |
Hemodialysis method for improving immune system function
|
|
US20050031651A1
(en)
*
|
2002-12-24 |
2005-02-10 |
Francine Gervais |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
MXPA05006940A
(es)
*
|
2002-12-24 |
2006-02-22 |
Neurochem Int Ltd |
Formulaciones terapeuticas para el tratamiento de enfermedades relacionadas con beta - amiloide.
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7521481B2
(en)
*
|
2003-02-27 |
2009-04-21 |
Mclaurin Joanne |
Methods of preventing, treating and diagnosing disorders of protein aggregation
|
|
WO2005000295A1
(en)
*
|
2003-05-20 |
2005-01-06 |
Transtech Pharma, Inc. |
Rage antagonists as agents to reverse amyloidosis and diseases associated therewith
|
|
US20060079578A1
(en)
*
|
2003-06-23 |
2006-04-13 |
Julie Laurin |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
US7253306B2
(en)
|
2003-06-23 |
2007-08-07 |
Neurochem (International) Limited |
Pharmaceutical drug candidates and methods for preparation thereof
|
|
MXPA05013977A
(es)
*
|
2003-06-23 |
2006-03-09 |
Neurochem Int Ltd |
Metodos y composiciones para tratar enfermedades relacionadas con amiloide.
|
|
US20070010573A1
(en)
*
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
|
EP1646375A2
(en)
*
|
2003-06-23 |
2006-04-19 |
Neurochem (International) Limited |
Treatment of protein aggregation disorders
|
|
AU2011250847B2
(en)
*
|
2003-06-23 |
2013-06-20 |
Bhi Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
US7244764B2
(en)
*
|
2003-06-23 |
2007-07-17 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US7414076B2
(en)
*
|
2003-06-23 |
2008-08-19 |
Neurochem (International) Limited |
Methods and compositions for treating amyloid-related diseases
|
|
US20050142191A1
(en)
*
|
2003-06-23 |
2005-06-30 |
Neurochem (International) Limited |
Pharmaceutical formulations of amyloid inhibiting compounds
|
|
BRPI0411800A
(pt)
*
|
2003-06-23 |
2006-08-08 |
Neurochem Int Ltd |
candidatos a fármacos e métodos para sua preparação
|
|
HRP20140442T1
(hr)
*
|
2003-06-23 |
2014-07-04 |
Kiacta Sàrl |
Metoda za pripremu spoja 1,3-propan disulfonske kiseline
|
|
US7262223B2
(en)
*
|
2004-01-23 |
2007-08-28 |
Neurochem (International) Limited |
Amidine derivatives for treating amyloidosis
|
|
WO2005077382A1
(ja)
*
|
2004-02-17 |
2005-08-25 |
National Institute Of Advanced Industrial Science And Technology |
プリオン増殖抑制剤
|
|
WO2005095633A1
(en)
*
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
EP1828111A2
(en)
*
|
2004-11-12 |
2007-09-05 |
Neurochem (International) Limited |
Methods and fluorinated compositions for treating amyloid-related diseases
|
|
AU2005310979A1
(en)
*
|
2004-11-16 |
2006-06-08 |
Bellus Health (International) Limited |
Compounds for the treatment of CNS and amyloid associated diseases
|
|
EP2186518A1
(en)
*
|
2004-11-17 |
2010-05-19 |
McLaurin, Joanne |
Composition and methods for treatment of disorders of protein aggregation
|
|
CA2900876A1
(en)
|
2004-12-22 |
2006-08-17 |
Bhi Limited Partnership |
Methods and compositions for treating amyloid-related diseases
|
|
KR20070120190A
(ko)
*
|
2005-04-12 |
2007-12-21 |
뉴로켐 (인터내셔널) 리미티드 |
아밀로이드 억제 화합물의 제약 제제
|
|
TW200716088A
(en)
*
|
2005-04-15 |
2007-05-01 |
Neurochem Int Ltd |
Formulations and methods for treating amyloidosis
|
|
AU2006251832A1
(en)
*
|
2005-05-27 |
2006-11-30 |
Queen's University At Kingston |
Treatment of protein folding disorders
|
|
WO2007023389A2
(en)
*
|
2005-07-21 |
2007-03-01 |
Neurochem (International) Limited |
Polymorphic forms of 3-amino-1-propanesulfonic acid
|
|
EP1937239A2
(en)
*
|
2005-09-30 |
2008-07-02 |
Neurochem (International) Limited |
Pharmaceutical compositions comprising carboxyalkylsulfonic acids
|
|
US20090170957A1
(en)
*
|
2005-10-13 |
2009-07-02 |
Antonio Cruz |
Scyllo-inositol derivatives and their use in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
|
|
EP1954718B1
(en)
|
2005-11-30 |
2014-09-03 |
AbbVie Inc. |
Anti-a globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies
|
|
WO2007064972A2
(en)
|
2005-11-30 |
2007-06-07 |
Abbott Laboratories |
Monoclonal antibodies against amyloid beta protein and uses thereof
|
|
ES2352801T3
(es)
*
|
2005-12-22 |
2011-02-23 |
Kiacta Sàrl |
Tratamiento de nefropatía diabética.
|
|
EP1976495A2
(en)
*
|
2006-01-06 |
2008-10-08 |
Aarhus Universitet |
Compounds acting on the serotonin transporter
|
|
US20070197452A1
(en)
*
|
2006-02-17 |
2007-08-23 |
Mclaurin Joanne |
Treatment of amyloid-related diseases
|
|
CN103054837A
(zh)
*
|
2006-03-09 |
2013-04-24 |
瓦拉塔药品公司 |
用于治疗蛋白积聚病症的环己烷多元醇制剂
|
|
WO2007134449A1
(en)
*
|
2006-05-19 |
2007-11-29 |
Waratah Pharmaceuticals Inc. |
Screening methods for amyloid beta modulators
|
|
WO2008034244A1
(en)
*
|
2006-09-21 |
2008-03-27 |
Waratah Pharmaceuticals Inc. |
The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases
|
|
DK3851447T3
(da)
|
2006-10-12 |
2023-12-04 |
Bellus Health Inc |
Fremgangsmåder, forbindelser, sammensætninger og vehikler til administration af 3-amino-1-propansulfonsyre
|
|
EP2091566A4
(en)
*
|
2006-11-24 |
2011-07-06 |
Waratah Pharmaceuticals Inc |
COMBINATION THERAPIES AGAINST ALZHEIMER DISEASE AND SIMILAR ILLNESSES
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
JP2010513219A
(ja)
*
|
2006-12-22 |
2010-04-30 |
ベラス ヘルス （インターナショナル） リミテッド |
腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療
|
|
AU2007337806A1
(en)
*
|
2006-12-22 |
2008-07-03 |
Bellus Health (International) Limited |
Methods, compounds, and compositions for treating metabolic disorders and diabetes
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
AR060412A1
(es)
*
|
2007-04-10 |
2008-06-18 |
Creactivar S A |
Una composicion farmaceutica utilizable para inhibir o evitar la formacion no deseada de tejido fibroso y uso de la n- sulfoetilnicotinamida para inhibir o evitar la formacion no deseada de tejido fibroso
|
|
AR060411A1
(es)
*
|
2007-04-10 |
2008-06-18 |
Creactivar S A |
Una composicion farmaceutica utilizable en el tratamiento o prevencion de una enfermedad pulmonar y uso de la n-sulfoetilnicotinamida en el tratamiento o prevencion de dicha enfermedad
|
|
CA2683548A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
|
|
PL2148667T3
(pl)
*
|
2007-04-12 |
2013-11-29 |
Waratah Pharmaceuticals Inc |
Stosowanie pochodnych cycloheksanoheksolu w leczeniu chorób oczu
|
|
WO2008124929A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
USE OF CYCLOHEXANEHEXOL DERIVATIVES IN THE TREATMENT OF α-SYNUCLEINOPATHIES
|
|
WO2008124931A1
(en)
*
|
2007-04-12 |
2008-10-23 |
Joanne Mclaurin |
Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis
|
|
US8613923B2
(en)
|
2007-06-12 |
2013-12-24 |
Ac Immune S.A. |
Monoclonal antibody
|
|
US8048420B2
(en)
|
2007-06-12 |
2011-11-01 |
Ac Immune S.A. |
Monoclonal antibody
|
|
PT2238166E
(pt)
|
2007-10-05 |
2014-02-11 |
Genentech Inc |
Utilização do anticorpo anti-amilóide beta em doenças oculares
|
|
US20100093648A1
(en)
*
|
2008-10-09 |
2010-04-15 |
Antonio Cruz |
Treatment of macular degeneration-related disorders
|
|
CN102471248B
(zh)
*
|
2009-08-10 |
2015-01-07 |
Bhi有限合伙公司 |
用于递送1,3-丙二磺酸的方法、化合物和组合物
|
|
NZ598861A
(en)
*
|
2009-09-17 |
2013-01-25 |
North Texas Medical Ass |
Role of n-2 hydroxy-ethyl-piperazine-n'-2-ethane sulfonic acid (hepes) in pain control and reversal of demyelinization injury
|
|
ES2467923T3
(es)
|
2009-09-30 |
2014-06-13 |
Transtech Pharma, Llc |
Derivados de imidazol substituidos para el tratamiento de la enfermedad de Alzheimer
|
|
KR101173677B1
(ko)
*
|
2009-12-11 |
2012-08-13 |
한국과학기술연구원 |
Ｅｐｐｓ를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물
|
|
WO2011130377A2
(en)
|
2010-04-15 |
2011-10-20 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
|
RU2607368C2
(ru)
|
2010-07-30 |
2017-01-10 |
Ац Иммуне С.А. |
Безопасные и функциональные гуманизированные антитела
|
|
MX358739B
(es)
|
2010-08-14 |
2018-09-03 |
Abbvie Inc Star |
Proteinas de union a amiloide beta.
|
|
US9717710B2
(en)
|
2012-10-05 |
2017-08-01 |
Vtv Therapeutics Llc |
Treatment of mild and moderate Alzheimer's disease
|
|
CA3054370A1
(en)
|
2017-02-24 |
2018-08-30 |
Alzheon, Inc. |
Methods for treating neurodegenerative disorders
|
|
CN114805211B
(zh)
|
2017-03-21 |
2024-08-23 |
润佳（苏州）医药科技有限公司 |
同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途
|
|
CN109394746A
(zh)
*
|
2017-08-15 |
2019-03-01 |
江西青峰药业有限公司 |
乙基硫酸铵在制备用于预防或治疗炎症性疾病药物中的应用
|
|
WO2019190822A1
(en)
|
2018-03-28 |
2019-10-03 |
Vtv Therapeutics Llc |
Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
|
|
WO2019190823A1
(en)
|
2018-03-28 |
2019-10-03 |
Vtv Therapeutics Llc |
Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
|
|
AU2019315853B2
(en)
*
|
2018-08-01 |
2025-05-01 |
Alzheon, Inc. |
Methods for treating neurodegenerative disorders
|
|
LT3829568T
(lt)
*
|
2018-08-01 |
2023-12-27 |
Alzheon, Inc. |
Sulfopropano rūgšties dariniai, skirti neurodegeneraciniams sutrikimams gydyti
|
|
JP7464591B2
(ja)
|
2018-10-10 |
2024-04-09 |
ブイティーブイ・セラピューティクス・エルエルシー |
［３－（４－｛２－ブチル－１－［４－（４－クロロ－フェノキシ）－フェニル］－１ｈ－イミダゾール－４－イル｝－フェノキシ）－プロピル］－ジエチル－アミンの代謝産物
|
|
CN116059192B
(zh)
|
2019-11-13 |
2024-10-29 |
润佳（苏州）医药科技有限公司 |
同位素富集的3-氨基-1-丙磺酸及其衍生物的用途
|