JPH10506791A - 治療用送達系としての微生物 - Google Patents
治療用送達系としての微生物Info
- Publication number
- JPH10506791A JPH10506791A JP8512318A JP51231896A JPH10506791A JP H10506791 A JPH10506791 A JP H10506791A JP 8512318 A JP8512318 A JP 8512318A JP 51231896 A JP51231896 A JP 51231896A JP H10506791 A JPH10506791 A JP H10506791A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- lactobacillus
- bacillus
- bacillus subtilis
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
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- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
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- Molecular Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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IT94A002025 | 1994-10-05 | ||
ITMI942025A IT1270123B (it) | 1994-10-05 | 1994-10-05 | Composizioni farmaceutiche contenenti microorganismi ingegnerizzati e loro uso per terapia |
PCT/EP1995/003921 WO1996011277A1 (en) | 1994-10-05 | 1995-10-04 | Microorganisms as therapeutic delivery systems |
Publications (1)
Publication Number | Publication Date |
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JPH10506791A true JPH10506791A (ja) | 1998-07-07 |
Family
ID=11369649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP8512318A Pending JPH10506791A (ja) | 1994-10-05 | 1995-10-04 | 治療用送達系としての微生物 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0784689A1 (it) |
JP (1) | JPH10506791A (it) |
AU (1) | AU3745395A (it) |
CA (1) | CA2201721A1 (it) |
IT (1) | IT1270123B (it) |
WO (1) | WO1996011277A1 (it) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002528392A (ja) * | 1998-10-20 | 2002-09-03 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー | 大腸炎処置のためのサイトカイン産生性ラクトコッカス株の使用 |
JP2003504025A (ja) * | 1999-07-05 | 2003-02-04 | フラームス・インテルウニフェルシタイル・インスティチュート・フォール・ビオテヒノロヒー | トレフォイルペプチドの送達 |
WO2006028214A1 (ja) | 2004-09-10 | 2006-03-16 | Asahi Glass Company, Limited | 経口投与ワクチン |
JP2008067708A (ja) * | 1995-10-20 | 2008-03-27 | Actogenix Nv | 生物学的に活性のあるポリペプチドのデリバリー |
JP2013517256A (ja) * | 2010-01-14 | 2013-05-16 | インセルム(インスティチュート ナショナル デ ラ サンテ エ デ ラ リシェルシェ メディカル) | 炎症性腸疾患(ibd)及び過敏性腸症候群(ibs)の予防及び治療のための組換体プロバイオティック細菌 |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6190657B1 (en) | 1995-06-07 | 2001-02-20 | Yale University | Vectors for the diagnosis and treatment of solid tumors including melanoma |
US6080849A (en) * | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
AU749695B2 (en) | 1997-09-10 | 2002-07-04 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
FR2791998B1 (fr) * | 1999-04-07 | 2001-06-08 | Agronomique Inst Nat Rech | Lactocoques modifies exprimant une catalase et leurs utilisations |
US6962696B1 (en) | 1999-10-04 | 2005-11-08 | Vion Pharmaceuticals Inc. | Compositions and methods for tumor-targeted delivery of effector molecules |
ATE381351T1 (de) * | 2000-07-27 | 2008-01-15 | Univ Pennsylvania | Anwendung des herpes simplex virus glykoproteins- d zur unterdrückung von immunantworten |
CA2342040C (en) | 2000-09-21 | 2012-07-10 | Kyowa Hakko Kogyo Co., Ltd. | Anaerobic bacterium as a drug for cancer gene therapy |
US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
WO2003063786A2 (en) * | 2002-01-31 | 2003-08-07 | Symbigene, Inc. | Methods and composition for delivering nucleic acids and/or proteins to the respiratory system |
WO2004007695A2 (en) * | 2002-03-08 | 2004-01-22 | Osel, Inc. | Lactobacilli expressing biologically active polypeptides and uses thereof |
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Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CA1321962C (en) * | 1985-03-20 | 1993-09-07 | Aizo Matsushiro | Dental caries preventive preparations and method for preparing said preparations |
-
1994
- 1994-10-05 IT ITMI942025A patent/IT1270123B/it active IP Right Grant
-
1995
- 1995-10-04 EP EP95935431A patent/EP0784689A1/en not_active Withdrawn
- 1995-10-04 CA CA002201721A patent/CA2201721A1/en not_active Abandoned
- 1995-10-04 JP JP8512318A patent/JPH10506791A/ja active Pending
- 1995-10-04 WO PCT/EP1995/003921 patent/WO1996011277A1/en not_active Application Discontinuation
- 1995-10-04 AU AU37453/95A patent/AU3745395A/en not_active Abandoned
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JP2008067708A (ja) * | 1995-10-20 | 2008-03-27 | Actogenix Nv | 生物学的に活性のあるポリペプチドのデリバリー |
JP2002528392A (ja) * | 1998-10-20 | 2002-09-03 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー | 大腸炎処置のためのサイトカイン産生性ラクトコッカス株の使用 |
JP2010222364A (ja) * | 1998-10-20 | 2010-10-07 | Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) | 大腸炎処置のためのサイトカイン産生性ラクトコッカス株の使用 |
JP2003504025A (ja) * | 1999-07-05 | 2003-02-04 | フラームス・インテルウニフェルシタイル・インスティチュート・フォール・ビオテヒノロヒー | トレフォイルペプチドの送達 |
JP4644401B2 (ja) * | 1999-07-05 | 2011-03-02 | アクトジェニックス・エヌブイ | トレフォイルペプチドの送達 |
WO2006028214A1 (ja) | 2004-09-10 | 2006-03-16 | Asahi Glass Company, Limited | 経口投与ワクチン |
US8282936B2 (en) | 2004-09-10 | 2012-10-09 | Asahi Glass Company, Ltd. | Human papillomavirus vaccine for oral administration |
JP2013517256A (ja) * | 2010-01-14 | 2013-05-16 | インセルム(インスティチュート ナショナル デ ラ サンテ エ デ ラ リシェルシェ メディカル) | 炎症性腸疾患(ibd)及び過敏性腸症候群(ibs)の予防及び治療のための組換体プロバイオティック細菌 |
Also Published As
Publication number | Publication date |
---|---|
ITMI942025A1 (it) | 1996-04-05 |
AU3745395A (en) | 1996-05-02 |
IT1270123B (it) | 1997-04-28 |
EP0784689A1 (en) | 1997-07-23 |
WO1996011277A1 (en) | 1996-04-18 |
CA2201721A1 (en) | 1996-04-18 |
ITMI942025A0 (it) | 1994-10-05 |
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