JPH08507549A - 水溶性の非免疫原性ポリアミド架橋剤 - Google Patents
水溶性の非免疫原性ポリアミド架橋剤Info
- Publication number
- JPH08507549A JPH08507549A JP7518149A JP51814995A JPH08507549A JP H08507549 A JPH08507549 A JP H08507549A JP 7518149 A JP7518149 A JP 7518149A JP 51814995 A JP51814995 A JP 51814995A JP H08507549 A JPH08507549 A JP H08507549A
- Authority
- JP
- Japan
- Prior art keywords
- polyamide
- group
- water
- soluble
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Polyamides (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17388293A | 1993-12-27 | 1993-12-27 | |
US08/173,882 | 1993-12-27 | ||
PCT/US1994/014821 WO1995017886A1 (fr) | 1993-12-27 | 1994-12-20 | Agents de reticulation a base de polyamides non immunogene hydrosoluble |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH08507549A true JPH08507549A (ja) | 1996-08-13 |
Family
ID=22633907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7518149A Pending JPH08507549A (ja) | 1993-12-27 | 1994-12-20 | 水溶性の非免疫原性ポリアミド架橋剤 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0702553A1 (fr) |
JP (1) | JPH08507549A (fr) |
AU (1) | AU1444095A (fr) |
CA (1) | CA2156924A1 (fr) |
WO (1) | WO1995017886A1 (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1400551B1 (fr) * | 1998-08-28 | 2007-06-13 | Amylin Pharmaceuticals, Inc. | Procédé de fabrication de chaines polyamides de longueur définie et leur conjugués avec des protéines |
AU764144B2 (en) | 1998-08-28 | 2003-08-14 | Gryphon Therapeutics, Inc. | Polyamide chains of precise length, methods to manufacture them and their conjugates |
WO2011034605A2 (fr) | 2009-09-16 | 2011-03-24 | Genentech, Inc. | Complexes protéiques contenant une super-hélice et/ou une attache et leurs utilisations |
AR080793A1 (es) | 2010-03-26 | 2012-05-09 | Roche Glycart Ag | Anticuerpos biespecificos |
WO2012085111A1 (fr) | 2010-12-23 | 2012-06-28 | F. Hoffmann-La Roche Ag | Complexe polypeptide-polynucléotide et son utilisation dans l'administration d'une fraction effectrice ciblée |
BR112013032235A2 (pt) | 2011-06-15 | 2016-11-22 | Hoffmann La Roche | anticorpos do receptor de epo anti-humano e métodos de uso |
RU2644341C2 (ru) | 2012-02-10 | 2018-02-08 | Дженентек, Инк. | Одноцепочечные антитела и другие гетеромультимеры |
CA2871882A1 (fr) | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Methode de fabrication de conjugues d'anticorps a region fc comprenant au moins une entite de liaison qui se lie specifiquement a une cible et leurs utilisations |
EP2867253B1 (fr) | 2012-06-27 | 2016-09-14 | F. Hoffmann-La Roche AG | Méthode de sélection et de production d'entités de ciblage personnalisées fortement sélectives et multi-spécifiques renfermant au moins deux entités de liaison différentes et leurs utilisations |
JP6445429B2 (ja) | 2012-06-27 | 2018-12-26 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 少なくとも2つの異なる標的化実体を含むテーラーメイドで選択的かつ多重特異性治療用分子を選択および作製するための方法およびその使用 |
SI3151921T1 (sl) | 2014-06-06 | 2019-12-31 | Bristol-Myers Squibb Company | Protitelesa proti z glukortikoidom induciranim receptorjem za faktor nekroze tumorja(GITR) in njihova uporaba |
HUE050596T2 (hu) | 2014-11-21 | 2020-12-28 | Bristol Myers Squibb Co | Antitestek CD73 ellen és azok felhasználásai |
EP3224277B1 (fr) | 2014-11-25 | 2020-08-26 | Bristol-Myers Squibb Company | Nouveaux polypeptides fixant pd-l1 pour l'imagerie |
CN107001482B (zh) | 2014-12-03 | 2021-06-15 | 豪夫迈·罗氏有限公司 | 多特异性抗体 |
JP6738348B2 (ja) | 2014-12-19 | 2020-08-12 | リジェネサンス ベスローテン フェンノートシャップ | ヒトc6に結合する抗体およびその使用 |
WO2016127052A1 (fr) | 2015-02-05 | 2016-08-11 | Bristol-Myers Squibb Company | Cxcl11 et smica comme biomarqueurs prédictifs de l'efficacité de l'immunothérapie anti-ctla-4 |
HRP20230060T1 (hr) | 2015-05-29 | 2023-03-17 | Bristol-Myers Squibb Company | Antitijela protiv ox40 i njihova primjena |
MX2018006072A (es) | 2015-11-19 | 2018-08-01 | Squibb Bristol Myers Co | Anticuerpos contra receptor de factor de necrosis de tumor inducido por glucocorticoides (gitr) y usos de los mismos. |
US20190284293A1 (en) | 2016-03-04 | 2019-09-19 | Bristol-Myers Squibb Company | Combination therapy with anti-cd73 antibodies |
KR102397783B1 (ko) | 2016-06-01 | 2022-05-12 | 브리스톨-마이어스 스큅 컴퍼니 | Pd-l1 결합 폴리펩티드에 의한 pet 영상화 |
TWI780057B (zh) | 2016-07-14 | 2022-10-11 | 美商必治妥美雅史谷比公司 | 針對tim3之抗體及其用途 |
JP7045724B2 (ja) | 2016-11-07 | 2022-04-01 | ニューラクル サイエンス カンパニー リミテッド | 配列類似性を持つ抗ファミリー19、メンバーa5抗体及びその用途 |
SG11201906947SA (en) | 2017-02-17 | 2019-08-27 | Bristol Myers Squibb Co | Antibodies to alpha-synuclein and uses thereof |
WO2019075090A1 (fr) | 2017-10-10 | 2019-04-18 | Tilos Therapeutics, Inc. | Anticorps anti-lap et leurs utilisations |
KR20200108870A (ko) | 2018-01-12 | 2020-09-21 | 브리스톨-마이어스 스큅 컴퍼니 | Tim3에 대한 항체 및 그의 용도 |
MX2020009861A (es) | 2018-03-23 | 2020-10-08 | Bristol Myers Squibb Co | Anticuerpos contra el complejo principal de histocompatibilidad relacionado con las cadenas a y b clase i (mica) y/o (micb) y sus usos. |
MA52190A (fr) | 2018-04-02 | 2021-02-17 | Bristol Myers Squibb Co | Anticorps anti-trem-1 et utilisations associées |
KR102661891B1 (ko) | 2018-05-10 | 2024-05-23 | 주식회사 뉴라클사이언스 | 서열 유사성 19, 멤버 a5 항체를 갖는 항-패밀리 및 그의 사용 방법 |
EP3841124A4 (fr) | 2018-06-29 | 2022-03-23 | ApitBio, Inc. | Anticorps anti-l1cam et leurs utilisations |
EP3863722A2 (fr) | 2018-10-10 | 2021-08-18 | Tilos Theapeutics, Inc. | Variants d'anticorps anti-lap et leurs utilisations |
US20210403602A1 (en) | 2018-12-03 | 2021-12-30 | Bristol-Myers Squibb Company | Anti-ido antibody and uses thereof |
PE20212305A1 (es) | 2019-01-22 | 2021-12-10 | Bristol Myers Squibb Co | Anticuerpos contra subunidad alfa il-7r y usos de estos |
CN114144435B (zh) | 2019-07-15 | 2024-06-25 | 百时美施贵宝公司 | 针对人trem-1的抗体及其用途 |
CN114174536A (zh) | 2019-07-15 | 2022-03-11 | 百时美施贵宝公司 | 抗trem-1抗体及其用途 |
WO2021207449A1 (fr) | 2020-04-09 | 2021-10-14 | Merck Sharp & Dohme Corp. | Anticorps anti-lap à maturation d'affinité et leurs utilisations |
JP2024514530A (ja) | 2021-04-02 | 2024-04-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 切断型cdcp1に対する抗体およびその使用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4168602A (en) * | 1975-03-11 | 1979-09-25 | Sun Ventures, Inc. | Block copolymer of poly (dioxaarylamide) and polyamide and fibers and fibrous material produced therefrom |
US5053520A (en) * | 1988-09-22 | 1991-10-01 | Abbott Laboratories | Heterobifunctional maleimido containing coupling agents |
-
1994
- 1994-12-20 AU AU14440/95A patent/AU1444095A/en not_active Abandoned
- 1994-12-20 WO PCT/US1994/014821 patent/WO1995017886A1/fr not_active Application Discontinuation
- 1994-12-20 JP JP7518149A patent/JPH08507549A/ja active Pending
- 1994-12-20 EP EP95906090A patent/EP0702553A1/fr not_active Withdrawn
- 1994-12-20 CA CA 2156924 patent/CA2156924A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1995017886A1 (fr) | 1995-07-06 |
CA2156924A1 (fr) | 1995-07-06 |
EP0702553A4 (fr) | 1996-01-19 |
EP0702553A1 (fr) | 1996-03-27 |
AU1444095A (en) | 1995-07-17 |
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