JPH08502280A - 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物 - Google Patents

新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物

Info

Publication number
JPH08502280A
JPH08502280A JP6509706A JP50970694A JPH08502280A JP H08502280 A JPH08502280 A JP H08502280A JP 6509706 A JP6509706 A JP 6509706A JP 50970694 A JP50970694 A JP 50970694A JP H08502280 A JPH08502280 A JP H08502280A
Authority
JP
Japan
Prior art keywords
group
carbon atoms
alkyl
general formula
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6509706A
Other languages
English (en)
Japanese (ja)
Inventor
ブルザ，ジヤン−ドミニク
コメルソン，アラン
ドプレ，ドミニク
ピユリカニ，ジヤン−ピエール
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH08502280A publication Critical patent/JPH08502280A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction
JP6509706A 1992-10-15 1993-10-13 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物 Pending JPH08502280A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR92/12331 1992-10-15
FR9212331A FR2697019B1 (fr) 1992-10-15 1992-10-15 Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1993/001013 WO1994008984A1 (fr) 1992-10-15 1993-10-13 Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
JPH08502280A true JPH08502280A (ja) 1996-03-12

Family

ID=9434565

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6509706A Pending JPH08502280A (ja) 1992-10-15 1993-10-13 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物

Country Status (15)

Country Link
EP (1) EP0664800A1 (fr)
JP (1) JPH08502280A (fr)
KR (1) KR950703551A (fr)
AU (1) AU5339594A (fr)
CA (1) CA2146765A1 (fr)
CZ (1) CZ95895A3 (fr)
FI (1) FI951789A (fr)
FR (1) FR2697019B1 (fr)
MX (1) MX9306227A (fr)
NO (1) NO951283L (fr)
PL (1) PL308361A1 (fr)
SK (1) SK49995A3 (fr)
TW (1) TW250480B (fr)
WO (1) WO1994008984A1 (fr)
ZA (1) ZA937558B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US6011056A (en) * 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
JP3892481B2 (ja) * 1993-03-05 2007-03-14 フロリダ・ステート・ユニバーシティー ９−デスオキソタキサンの製法
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
US5635531A (en) * 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
US5977386A (en) * 1996-12-24 1999-11-02 Bristol-Myers Squibb Company 6-thio-substituted paclitaxels
US5902822A (en) * 1997-02-28 1999-05-11 Bristol-Myers Squibb Company 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US6017935A (en) * 1997-04-24 2000-01-25 Bristol-Myers Squibb Company 7-sulfur substituted paclitaxels
EP1894921A3 (fr) * 2003-09-25 2008-03-12 Tapestry Pharmaceuticals, Inc. Analogues de 9,10-alpha, alpha-Oh-Taxane et procédés de fabrication correspondants
EP1664033B1 (fr) 2003-09-25 2007-11-07 Tapestry Pharmaceuticals, Inc. Analogues de 9,10-alpha,alpha-oh-taxane et procedes de fabrication correspondants
WO2008106621A1 (fr) 2007-02-28 2008-09-04 Tapestry Pharmaceuticals, Inc Analogues de taxane destinés à traiter un cancer du cerveau
US11786504B2 (en) 2006-09-28 2023-10-17 Tapestry Pharmaceuticals, Inc. Taxane analogs for the treatment of brain cancer
US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
WO2008121476A1 (fr) 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Analogues de taxane biologiquement actifs, et procédés de traitement par administration orale
JP5847942B2 (ja) 2012-07-19 2016-01-27 富士フイルム株式会社 タキサン系活性成分含有液体組成物、その製造方法及び液体製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene

Also Published As

Publication number Publication date
PL308361A1 (en) 1995-07-24
EP0664800A1 (fr) 1995-08-02
FR2697019A1 (fr) 1994-04-22
NO951283D0 (no) 1995-04-03
SK49995A3 (en) 1995-09-13
CZ95895A3 (en) 1995-09-13
CA2146765A1 (fr) 1994-04-28
KR950703551A (ko) 1995-09-20
FR2697019B1 (fr) 1994-11-25
ZA937558B (en) 1994-05-04
FI951789A0 (fi) 1995-04-13
NO951283L (no) 1995-04-03
FI951789A (fi) 1995-04-13
MX9306227A (es) 1994-05-31
TW250480B (fr) 1995-07-01
WO1994008984A1 (fr) 1994-04-28
AU5339594A (en) 1994-05-09

Similar Documents

Publication Publication Date Title
JPH08502280A (ja) 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物
JPH08503261A (ja) タキサン誘導体の製造法、それにより得られる新規タキサンならびにそれらを含む抗腫瘍及び抗白血病性組成物
JP3782443B2 (ja) 新規タキソイド類、それらの製造及びそれらを含む製薬学的組成物
JPH09504801A (ja) 新規なタキソイド類、それらの製造およびそれらを含有する製剤組成物
CN102574861B (zh) 甲基吡咯并嘧啶甲酰胺
JPH07504461A (ja) タキサン誘導体の製造法
BG62697B1 (bg) Нови таксоиди, получаването им и фармацевтични състави, които ги съдържат
FR2711369A1 (fr) Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
JP2017522383A (ja) 酵素阻害に用いられるエポキシケトン化合物
CA2153419C (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
Tomilov et al. Electrochemical synthesis of diethyl fluoromethanephosphonate
WO1995009163A1 (fr) Procede de preparation de taxoides
HUT73250A (en) Novel taxoids, preparation thereof and pharmaceutical compositions containing same
FR2721025A1 (fr) Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
JP2006506096A (ja) ジオキソランヌクレオシド類似体の立体選択的製造方法
JPH07173118A (ja) 不斉的に置換されたジアミノジカルボン酸誘導体とそれらの製造方法