NO951283L - Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivatene - Google Patents
Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivateneInfo
- Publication number
- NO951283L NO951283L NO951283A NO951283A NO951283L NO 951283 L NO951283 L NO 951283L NO 951283 A NO951283 A NO 951283A NO 951283 A NO951283 A NO 951283A NO 951283 L NO951283 L NO 951283L
- Authority
- NO
- Norway
- Prior art keywords
- residue
- derivatives
- general formula
- preparation
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/20—Processes
- C25B3/25—Reduction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Electrochemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Nye taxanderivater med den generelle formel (I): fremstilles ved elektrokjemisk reduksjon av et taxanderlvat med den HO. R generelle formel (III): OK Rl-Ot HO I formel (I) betyr et av symbolene % og R2 et hydrogenatom og det andre en hydrokfiyrest, R3 et hydrogenatom eller en rest med den generelle formel (II): der Ar betyr en arylrest, R*'N? f? fy betyr en benzylrest eller en rest R5-0-CO-der R5 betyr en alkyl-, Arx>*X!x^\. ¿¿ alkenyl-, cykloalkyl-, cykloalkenyl-, blcykloalkyl-, fenyl- eller 5H heterocyklylrest og 6° betyr en alkyl-, alkenyl-, cykloalkyl-, cykloalkenyl-, blcyklo- alkyl-, eventuelt substituert aryl- eller heterocyklylrest. Forbindelser med den generelle formel (I) der R3 betyr en rest med den generelle formel (II) oppviser bemerkelsesverdige antltumorale og antlleukemlske egenskaper.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9212331A FR2697019B1 (fr) | 1992-10-15 | 1992-10-15 | Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent. |
PCT/FR1993/001013 WO1994008984A1 (fr) | 1992-10-15 | 1993-10-13 | Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
NO951283L true NO951283L (no) | 1995-04-03 |
NO951283D0 NO951283D0 (no) | 1995-04-03 |
Family
ID=9434565
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO951283A NO951283D0 (no) | 1992-10-15 | 1995-04-03 | Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivatene |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0664800A1 (no) |
JP (1) | JPH08502280A (no) |
KR (1) | KR950703551A (no) |
AU (1) | AU5339594A (no) |
CA (1) | CA2146765A1 (no) |
CZ (1) | CZ95895A3 (no) |
FI (1) | FI951789A (no) |
FR (1) | FR2697019B1 (no) |
MX (1) | MX9306227A (no) |
NO (1) | NO951283D0 (no) |
PL (1) | PL308361A1 (no) |
SK (1) | SK49995A3 (no) |
TW (1) | TW250480B (no) |
WO (1) | WO1994008984A1 (no) |
ZA (1) | ZA937558B (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495704B1 (en) | 1991-09-23 | 2002-12-17 | Florida State University | 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes |
US6011056A (en) | 1991-09-23 | 2000-01-04 | Florida State University | C9 taxane derivatives and pharmaceutical compositions containing them |
US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
US6710191B2 (en) | 1993-03-05 | 2004-03-23 | Florida State University | 9β-hydroxytetracyclic taxanes |
AU689770B2 (en) * | 1993-03-05 | 1998-04-09 | Florida State University | Process for the preparation of 9-desoxotaxanes |
US5703247A (en) * | 1993-03-11 | 1997-12-30 | Virginia Tech Intellectual Properties, Inc. | 2-Debenzoyl-2-acyl taxol derivatives and methods for making same |
US5635531A (en) * | 1996-07-08 | 1997-06-03 | Bristol-Myers Squibb Company | 3'-aminocarbonyloxy paclitaxels |
US5773464A (en) * | 1996-09-30 | 1998-06-30 | Bristol-Myers Squibb Company | C-10 epoxy taxanes |
US5977386A (en) * | 1996-12-24 | 1999-11-02 | Bristol-Myers Squibb Company | 6-thio-substituted paclitaxels |
US5902822A (en) * | 1997-02-28 | 1999-05-11 | Bristol-Myers Squibb Company | 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels |
US5912264A (en) * | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
US6017935A (en) * | 1997-04-24 | 2000-01-25 | Bristol-Myers Squibb Company | 7-sulfur substituted paclitaxels |
PL1664033T3 (pl) | 2003-09-25 | 2008-04-30 | Tapestry Pharmaceuticals Inc | Analogi 9,10-alfa, alfa-OH-taksanu i sposoby ich wytwarzania |
SI1664033T1 (sl) * | 2003-09-25 | 2008-04-30 | Tapestry Pharmaceuticals Inc | Analogi 9,10-alfa,alfa-oh-taksana in postopki za proizvodnjo le-teh |
US11786504B2 (en) | 2006-09-28 | 2023-10-17 | Tapestry Pharmaceuticals, Inc. | Taxane analogs for the treatment of brain cancer |
WO2008121476A1 (en) | 2007-03-28 | 2008-10-09 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
US11873308B2 (en) | 2006-11-06 | 2024-01-16 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
WO2008109360A1 (en) | 2007-02-28 | 2008-09-12 | Tapestry Pharmaceuticals, Inc | Taxane analogs for the treatment of brain cancer |
CN108158991A (zh) | 2012-07-19 | 2018-06-15 | 富士胶片株式会社 | 含紫杉烷系活性成分的液体组合物、其制造方法及液体制剂 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
US5059699A (en) * | 1990-08-28 | 1991-10-22 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
MX9102128A (es) * | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
-
1992
- 1992-10-15 FR FR9212331A patent/FR2697019B1/fr not_active Expired - Fee Related
-
1993
- 1993-10-06 MX MX9306227A patent/MX9306227A/es unknown
- 1993-10-12 ZA ZA937558A patent/ZA937558B/xx unknown
- 1993-10-13 JP JP6509706A patent/JPH08502280A/ja active Pending
- 1993-10-13 AU AU53395/94A patent/AU5339594A/en not_active Abandoned
- 1993-10-13 EP EP93923578A patent/EP0664800A1/fr not_active Withdrawn
- 1993-10-13 CZ CZ95958A patent/CZ95895A3/cs unknown
- 1993-10-13 PL PL93308361A patent/PL308361A1/xx unknown
- 1993-10-13 WO PCT/FR1993/001013 patent/WO1994008984A1/fr not_active Application Discontinuation
- 1993-10-13 CA CA002146765A patent/CA2146765A1/fr not_active Abandoned
- 1993-10-13 KR KR1019950701443A patent/KR950703551A/ko not_active Application Discontinuation
- 1993-10-13 TW TW082108451A patent/TW250480B/zh active
- 1993-10-13 SK SK499-95A patent/SK49995A3/sk unknown
-
1995
- 1995-04-03 NO NO951283A patent/NO951283D0/no unknown
- 1995-04-13 FI FI951789A patent/FI951789A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW250480B (no) | 1995-07-01 |
MX9306227A (es) | 1994-05-31 |
EP0664800A1 (fr) | 1995-08-02 |
JPH08502280A (ja) | 1996-03-12 |
PL308361A1 (en) | 1995-07-24 |
WO1994008984A1 (fr) | 1994-04-28 |
KR950703551A (ko) | 1995-09-20 |
ZA937558B (en) | 1994-05-04 |
CZ95895A3 (en) | 1995-09-13 |
FI951789A0 (fi) | 1995-04-13 |
CA2146765A1 (fr) | 1994-04-28 |
AU5339594A (en) | 1994-05-09 |
FR2697019A1 (fr) | 1994-04-22 |
FR2697019B1 (fr) | 1994-11-25 |
SK49995A3 (en) | 1995-09-13 |
NO951283D0 (no) | 1995-04-03 |
FI951789A (fi) | 1995-04-13 |
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