NO951772L - Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye taxaner samt antitumor- og antileukemipreparater inneholdende taxanene - Google Patents
Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye taxaner samt antitumor- og antileukemipreparater inneholdende taxaneneInfo
- Publication number
- NO951772L NO951772L NO951772A NO951772A NO951772L NO 951772 L NO951772 L NO 951772L NO 951772 A NO951772 A NO 951772A NO 951772 A NO951772 A NO 951772A NO 951772 L NO951772 L NO 951772L
- Authority
- NO
- Norway
- Prior art keywords
- residue
- taxanes
- general formula
- tumor
- leukemia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B3/00—Electrolytic production of organic compounds
- C25B3/20—Processes
- C25B3/25—Reduction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
- C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
- C25B11/042—Electrodes formed of a single material
- C25B11/046—Alloys
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
- C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
- C25B9/17—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
- C25B9/19—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
- C25B9/23—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Metallurgy (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
En fremgangsmåte for fremstilling av taxanderlvater med den generelle formel (I): der R betyr et hydrogenatom eller en acetyl- eller alkoksyacetylrest, et av symbolene R^ og R2 betyr et hydrogenatom og den andre betyr en hydroksyrest, R3 betyr et hydrogenatom eller en rest med den generelle formel (II): R4-NH R-,-0" HO OCOCH- Ar HO ococ6H5 der Ar betyr en arylrest og R4 betyr en benzoylrest eller en rest Rs-O-CO-, der RS betyr en alkyl-, alkenyl-, cykloalkyl-, cykloalkenyl, blcykloalkyl-, fenyl eller heterocyklylrest, på elektrokjemisk måte fra et taxan- derlvat med den generelle formel (III): der substltuentene har den ovenfor angitte betydning. R-0 -K2 R-,-0" Farmasøytiske preparater som Inneholder en ny forbindelse med den generelle formel (I) der R3 betyr en rest med den generelle formel (II), oppviser Interessante antltumorale og antlleukemlske egenskaper.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9213586A FR2697841B1 (fr) | 1992-11-12 | 1992-11-12 | Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent. |
PCT/FR1993/001102 WO1994011547A1 (fr) | 1992-11-12 | 1993-11-10 | Procede de preparation de derives du taxane, nouveaux taxanes ainsi obtenus et les compositions antitumorales et antileucemiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
NO951772D0 NO951772D0 (no) | 1995-05-05 |
NO951772L true NO951772L (no) | 1995-05-05 |
Family
ID=9435452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO951772A NO951772L (no) | 1992-11-12 | 1995-05-05 | Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye taxaner samt antitumor- og antileukemipreparater inneholdende taxanene |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0667922A1 (no) |
JP (1) | JPH08503261A (no) |
KR (1) | KR950704540A (no) |
AU (1) | AU5425794A (no) |
CA (1) | CA2149240A1 (no) |
CZ (1) | CZ122495A3 (no) |
FI (1) | FI952294A (no) |
FR (1) | FR2697841B1 (no) |
MX (1) | MX9306883A (no) |
NO (1) | NO951772L (no) |
PL (1) | PL308957A1 (no) |
RU (1) | RU95112464A (no) |
SK (1) | SK60895A3 (no) |
WO (1) | WO1994011547A1 (no) |
ZA (1) | ZA938366B (no) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
FR2710642B1 (fr) * | 1993-09-29 | 1995-11-17 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
FR2711369B1 (fr) * | 1993-10-20 | 1995-11-17 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent. |
US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
EP0914116B1 (en) * | 1996-05-22 | 2000-10-11 | Protarga Inc. | Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere |
US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US7235583B1 (en) | 1999-03-09 | 2007-06-26 | Luitpold Pharmaceuticals, Inc., | Fatty acid-anticancer conjugates and uses thereof |
US8309603B2 (en) | 2004-06-07 | 2012-11-13 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
MXPA06008293A (es) * | 2004-01-22 | 2007-06-11 | Univ Miami | Formulaciones topicas de coenzima q10 y metodos de uso. |
US9889110B2 (en) | 2004-06-07 | 2018-02-13 | University Of Tennessee Research Foundation | Selective androgen receptor modulator for treating hormone-related conditions |
US9884038B2 (en) | 2004-06-07 | 2018-02-06 | University Of Tennessee Research Foundation | Selective androgen receptor modulator and methods of use thereof |
US9730908B2 (en) | 2006-08-24 | 2017-08-15 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US10010521B2 (en) | 2006-08-24 | 2018-07-03 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US9844528B2 (en) | 2006-08-24 | 2017-12-19 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
EA201101522A1 (ru) | 2009-05-11 | 2012-09-28 | БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи | Способы лечения болезней с использованием эпиметаболического переключателя (коэнзим q10) |
EP2694463B8 (en) | 2011-04-04 | 2019-10-09 | Berg LLC | Treating central nervous system tumors with coenzyme q10 |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
WO2014168993A1 (en) | 2013-04-08 | 2014-10-16 | Berg Llc | Treatment of cancer using coenzyme q10 combination therapies |
WO2015035094A1 (en) | 2013-09-04 | 2015-03-12 | Berg Llc | Methods of treatment of cancer by continuous infusion of coenzyme q10 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
-
1992
- 1992-11-12 FR FR9213586A patent/FR2697841B1/fr not_active Expired - Fee Related
-
1993
- 1993-11-04 MX MX9306883A patent/MX9306883A/es unknown
- 1993-11-09 ZA ZA938366A patent/ZA938366B/xx unknown
- 1993-11-10 EP EP93924688A patent/EP0667922A1/fr not_active Withdrawn
- 1993-11-10 WO PCT/FR1993/001102 patent/WO1994011547A1/fr not_active Application Discontinuation
- 1993-11-10 PL PL93308957A patent/PL308957A1/xx unknown
- 1993-11-10 JP JP6511786A patent/JPH08503261A/ja active Pending
- 1993-11-10 CA CA002149240A patent/CA2149240A1/fr not_active Abandoned
- 1993-11-10 AU AU54257/94A patent/AU5425794A/en not_active Abandoned
- 1993-11-10 RU RU95112464/04A patent/RU95112464A/ru unknown
- 1993-11-10 KR KR1019950701883A patent/KR950704540A/ko not_active Application Discontinuation
- 1993-11-10 SK SK608-95A patent/SK60895A3/sk unknown
- 1993-11-10 CZ CZ951224A patent/CZ122495A3/cs unknown
-
1995
- 1995-05-05 NO NO951772A patent/NO951772L/no unknown
- 1995-05-11 FI FI952294A patent/FI952294A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO951772D0 (no) | 1995-05-05 |
FI952294A0 (fi) | 1995-05-11 |
CZ122495A3 (en) | 1995-12-13 |
KR950704540A (ko) | 1995-11-20 |
FR2697841B1 (fr) | 1995-01-13 |
CA2149240A1 (fr) | 1994-05-26 |
SK60895A3 (en) | 1996-03-06 |
MX9306883A (es) | 1995-01-31 |
ZA938366B (en) | 1994-06-13 |
WO1994011547A1 (fr) | 1994-05-26 |
FR2697841A1 (fr) | 1994-05-13 |
PL308957A1 (en) | 1995-09-04 |
EP0667922A1 (fr) | 1995-08-23 |
FI952294A (fi) | 1995-05-11 |
JPH08503261A (ja) | 1996-04-09 |
RU95112464A (ru) | 1997-02-20 |
AU5425794A (en) | 1994-06-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO951772L (no) | Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye taxaner samt antitumor- og antileukemipreparater inneholdende taxanene | |
BR9307613A (pt) | Novos taxóides processo de preparação de um taxóide e composição farmacêutica | |
AU2212392A (en) | Novel alkoxy substituted taxanes and pharmaceutical compositions containing them | |
AU2212292A (en) | Novel furyl and thienyl substituted taxanes and pharmaceutical compositions containing them | |
EP0356214A3 (en) | Thiazolidine dione derivatives | |
NO951283L (no) | Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivatene | |
PL310441A1 (en) | Novel taxoides, method of obtaining them and pharmaceutical compositions containing such compounds | |
TW427988B (en) | Process for the preparation of taxane derivatives | |
HUT41713A (en) | Process for production of //arol-cyclobutyl/ alkyl/-amins and medical preparatives containing thereof | |
NO974563L (no) | Nye taxoider, deres fremstilling samt farmasöytiske preparater inneholdende forbindelsene | |
RU94041682A (ru) | Способ получения производных таксана | |
IL81733A0 (en) | Penem derivatives,their preparation and pharmaceutical compositions containing them | |
MX9604465A (es) | Procedimiento de preparacion de 7-hidroxi-taxanos. |