MX9306883A - Nuevos derivados de taxano, procedimiento para su obtencion y composicionfarmaceutica que los contiene. - Google Patents

Nuevos derivados de taxano, procedimiento para su obtencion y composicionfarmaceutica que los contiene.

Info

Publication number
MX9306883A
MX9306883A MX9306883A MX9306883A MX9306883A MX 9306883 A MX9306883 A MX 9306883A MX 9306883 A MX9306883 A MX 9306883A MX 9306883 A MX9306883 A MX 9306883A MX 9306883 A MX9306883 A MX 9306883A
Authority
MX
Mexico
Prior art keywords
radical
general formula
taxane
hydrogen atom
procedure
Prior art date
Application number
MX9306883A
Other languages
English (en)
Inventor
Jean-Dominique Bourzat
Alain Commercon
Dominique Deprez
Jean-Pierre Pulicani
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9306883A publication Critical patent/MX9306883A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
    • C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
    • C25B11/042—Electrodes formed of a single material
    • C25B11/046—Alloys
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/17—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
    • C25B9/19—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
    • C25B9/23—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded

Abstract

La presente invención se refiere a un procedimiento de preparación dederivados de taxano de la fórmula general (I), por vía electroquímica, apartir de un derivado de taxano de la fórmula general (III) y acomposiciones farmacéuticas que contienen un nuevo producto de la fórmulageneral (I) en donde R3 representa un radical de la formula general (II),las cuales presentan propiedades antitumorales y antileucémicasremarcables. En las fórmulas generales (I) y (III), R representa un átomode hidrógeno o un radical acetilo o alcoxiacetilo, R1 o R2 representa unátomo de hidrógeno y el otro representa un radical hidroxilo. R3representa un átomo de hidrógeno o un radical de la fórmula general (II)en donde: Ar representa un radical arilo y R4 representa un radicalbenzoilo o un radical R5-O-CO, en donde R5 representa un radical alquilo,alquenilo, cicloalquilo, cicloalquenilo, bicicloalquilo, fenilo oheterociclilo.
MX9306883A 1992-11-12 1993-11-04 Nuevos derivados de taxano, procedimiento para su obtencion y composicionfarmaceutica que los contiene. MX9306883A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213586A FR2697841B1 (fr) 1992-11-12 1992-11-12 Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
MX9306883A true MX9306883A (es) 1995-01-31

Family

ID=9435452

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306883A MX9306883A (es) 1992-11-12 1993-11-04 Nuevos derivados de taxano, procedimiento para su obtencion y composicionfarmaceutica que los contiene.

Country Status (15)

Country Link
EP (1) EP0667922A1 (es)
JP (1) JPH08503261A (es)
KR (1) KR950704540A (es)
AU (1) AU5425794A (es)
CA (1) CA2149240A1 (es)
CZ (1) CZ122495A3 (es)
FI (1) FI952294A0 (es)
FR (1) FR2697841B1 (es)
MX (1) MX9306883A (es)
NO (1) NO951772L (es)
PL (1) PL308957A1 (es)
RU (1) RU95112464A (es)
SK (1) SK60895A3 (es)
WO (1) WO1994011547A1 (es)
ZA (1) ZA938366B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
FR2710642B1 (fr) * 1993-09-29 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2711369B1 (fr) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
DE69703294T2 (de) * 1996-05-22 2001-05-17 Protarga Inc Zusammensetzungen die konjugate von cis-docosahexaenoic-säure und taxotere enthalten
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US8309603B2 (en) 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
EP2371364B1 (en) * 2004-01-22 2016-10-19 University of Miami Topical or intravenous co-enzyme q10 formulations for use in treating cancer
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
EA201101519A1 (ru) 2009-05-11 2012-10-30 БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи Способы диагностики метаболических нарушений, использующие эпиметаболические переключатели, многоаспектные внутриклеточные молекулы или факторы влияния
ES2762451T3 (es) 2011-04-04 2020-05-25 Berg Llc Tratamiento de tumores del sistema nervioso central con coenzima Q10
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
CN105338973A (zh) 2013-04-08 2016-02-17 博格有限责任公司 使用辅酶q10联合疗法治疗癌症
EP3041496B1 (en) 2013-09-04 2020-04-29 Berg LLC Methods of treatment of cancer by continuous infusion of coenzyme q10

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NO951772D0 (no) 1995-05-05
FI952294A (fi) 1995-05-11
RU95112464A (ru) 1997-02-20
EP0667922A1 (fr) 1995-08-23
SK60895A3 (en) 1996-03-06
FR2697841A1 (fr) 1994-05-13
FR2697841B1 (fr) 1995-01-13
JPH08503261A (ja) 1996-04-09
AU5425794A (en) 1994-06-08
NO951772L (no) 1995-05-05
WO1994011547A1 (fr) 1994-05-26
FI952294A0 (fi) 1995-05-11
PL308957A1 (en) 1995-09-04
KR950704540A (ko) 1995-11-20
ZA938366B (en) 1994-06-13
CZ122495A3 (en) 1995-12-13
CA2149240A1 (fr) 1994-05-26

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