CA2149240A1 - Procede de preparation de derives du taxane, nouveaux taxanes ainsi obtenus et les compositions antitumorales et antileucemiques qui les contiennent - Google Patents

Procede de preparation de derives du taxane, nouveaux taxanes ainsi obtenus et les compositions antitumorales et antileucemiques qui les contiennent

Info

Publication number
CA2149240A1
CA2149240A1 CA002149240A CA2149240A CA2149240A1 CA 2149240 A1 CA2149240 A1 CA 2149240A1 CA 002149240 A CA002149240 A CA 002149240A CA 2149240 A CA2149240 A CA 2149240A CA 2149240 A1 CA2149240 A1 CA 2149240A1
Authority
CA
Canada
Prior art keywords
radical
carbon atoms
alkyl
radicals
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002149240A
Other languages
English (en)
French (fr)
Inventor
Jean-Dominique Bourzat
Alain Commercon
Dominique Deprez
Jean-Pierre Pulicani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2149240A1 publication Critical patent/CA2149240A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B11/00—Electrodes; Manufacture thereof not otherwise provided for
    • C25B11/04—Electrodes; Manufacture thereof not otherwise provided for characterised by the material
    • C25B11/042—Electrodes formed of a single material
    • C25B11/046—Alloys
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/17—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
    • C25B9/19—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
    • C25B9/23—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
CA002149240A 1992-11-12 1993-11-10 Procede de preparation de derives du taxane, nouveaux taxanes ainsi obtenus et les compositions antitumorales et antileucemiques qui les contiennent Abandoned CA2149240A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR92/13586 1992-11-12
FR9213586A FR2697841B1 (fr) 1992-11-12 1992-11-12 Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
CA2149240A1 true CA2149240A1 (fr) 1994-05-26

Family

ID=9435452

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002149240A Abandoned CA2149240A1 (fr) 1992-11-12 1993-11-10 Procede de preparation de derives du taxane, nouveaux taxanes ainsi obtenus et les compositions antitumorales et antileucemiques qui les contiennent

Country Status (15)

Country Link
EP (1) EP0667922A1 (es)
JP (1) JPH08503261A (es)
KR (1) KR950704540A (es)
AU (1) AU5425794A (es)
CA (1) CA2149240A1 (es)
CZ (1) CZ122495A3 (es)
FI (1) FI952294A (es)
FR (1) FR2697841B1 (es)
MX (1) MX9306883A (es)
NO (1) NO951772D0 (es)
PL (1) PL308957A1 (es)
RU (1) RU95112464A (es)
SK (1) SK60895A3 (es)
WO (1) WO1994011547A1 (es)
ZA (1) ZA938366B (es)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9278914B2 (en) 2004-06-07 2016-03-08 University Of Tennessee Research Foundation SARMs and method of use thereof
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US11090283B2 (en) 2007-09-11 2021-08-17 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
FR2710642B1 (fr) * 1993-09-29 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2711369B1 (fr) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
CA2255615C (en) * 1996-05-22 2006-08-29 Neuromedica, Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and docetaxel
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
KR20160106194A (ko) * 2004-01-22 2016-09-09 유니버시티 오브 마이애미 국소용 코-엔자임 큐10 제형 및 그의 사용 방법
BRPI1010648A2 (pt) 2009-05-11 2016-03-15 Berg Biosystems Llc métodos para o diagnóstico de distúrbios oncológicos usando transferidores epimetabólicos, moléculas intracelulares multidimensionais ou influenciadores ambientais
KR101933732B1 (ko) 2011-04-04 2018-12-28 버그 엘엘씨 중추 신경 시스템 종양들의 치료 방법
CA2909094C (en) 2013-04-08 2023-06-27 Berg Llc Methods for the treatment of cancer using coenzyme q10 combination therapies
EP3730131A1 (en) 2013-09-04 2020-10-28 Berg LLC Methods of treatment of cancer by continuous infusion of coenzyme q10

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9278914B2 (en) 2004-06-07 2016-03-08 University Of Tennessee Research Foundation SARMs and method of use thereof
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
US10053418B2 (en) 2004-06-07 2018-08-21 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US10662148B2 (en) 2004-06-07 2020-05-26 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US10300037B2 (en) 2006-08-24 2019-05-28 University Of Tennessee Research Foundation SARMs and method of use thereof
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
US11090283B2 (en) 2007-09-11 2021-08-17 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)

Also Published As

Publication number Publication date
MX9306883A (es) 1995-01-31
AU5425794A (en) 1994-06-08
EP0667922A1 (fr) 1995-08-23
ZA938366B (en) 1994-06-13
NO951772L (no) 1995-05-05
PL308957A1 (en) 1995-09-04
CZ122495A3 (en) 1995-12-13
JPH08503261A (ja) 1996-04-09
WO1994011547A1 (fr) 1994-05-26
FI952294A0 (fi) 1995-05-11
FR2697841B1 (fr) 1995-01-13
RU95112464A (ru) 1997-02-20
FR2697841A1 (fr) 1994-05-13
NO951772D0 (no) 1995-05-05
FI952294A (fi) 1995-05-11
KR950704540A (ko) 1995-11-20
SK60895A3 (en) 1996-03-06

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Legal Events

Date Code Title Description
FZDE Discontinued